47 research outputs found
End-Stage Renal Disease From Cast Nephropathy in a Teenager With Neuroendocrine Carcinoma
No full textPrimary Renal Lymphoma Presenting as End-Stage Renal Disease
No full textPrimary renal lymphoma is a rare entity, even more so in children. Children with primary renal lymphoma present with variable clinical features such as constitutional signs and symptoms, acute kidney injury, palpable abdominal masses, and gross hematuria. Herein we report a child who presented with seemingly advanced chronic kidney disease and was eventually diagnosed with primary lymphoma. He responded well to intensive chemotherapy and recovered renal function, although he was left with some functional limitations as a consequence of his treatment regimen. Our report highlights the importance of keeping neoplastic conditions under consideration when taking care of children with severe kidney disease of unclear etiology
WHOLE GENOME COMPARISONS REVEALS A POSSIBLE CHIMERIC ORIGIN FOR A MAJOR METAZOAN ASSEMBLAGE
No full text The availability of whole genome sequences from multiple metazoan phyla is making it possible to determine their phylogeny. We have found that a sea urchin and human define a clade that excludes a tunicate, contradicting both classical and recent molecular studies that place the tunicate and vertebrate in the Chordate phylum. Intriguingly, by means of a novel four taxa analysis, we have partitioned the 2000 proteins responsible for this assignment into two groups. One group, containing about 40% of the proteins, supports the classical assemblage of the tunicate with vertebrates, while the remaining group places the tunicate outside of the chordate assemblage. The existence of these two phylogenetic groups is robustly maintained in five, six and nine taxa analyses. These results suggest that major horizontal gene transfer events occurred during the emergence of one of the metazoan phyla. The simplest explanation is that the modern tunicate (as represented by Ciona intestinalis) began as a hybrid between a primitive vertebrate and some other organism, perhaps from an extinct and unidentified protostome phylum, at a time close to but after the diversification of the chordates and echinoderms and before the lineages leading to Drosophila melanogaster and Caenorhabditis elegans diverged. </jats:p
EDTA alkaline elution characteristics and measurement of DNA damage in unlabeled DNA using hoechst 33258 fluorescence
No full textINDUCTION OF DNA STRAND BREAKS IN NORMAL HUMAN FIBROBLASTS EXPOSED TO MONOCHROMATIC ULTRAVIOLET AND VISIBLE WAVELENGTHS IN THE 240–546 nm RANGE
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Assessing Safe Discharge Criteria for Pediatric Oncology Patients Admitted for Febrile Neutropenia
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