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    Study of titania modified porous alumina membranes for protein transport and separation

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    Monessha Nambiar, Peter J. Evans, Gerry Triani, Joe G. Shapter, Dusan Losi

    Gold Nanotube Membranes: membrane materials, characterization, and module design

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    AbstractIn this review, we discuss gold nanotube membranes, which are of interest in the field of membrane separations. The review briefly describes the template synthesis approach based on electroless gold deposition for production of these membranes using polymer track‐etched and porous alumina membranes as a template. Separation using gold nanotube membranes based on strategies such as molecular size exclusion, charge, and molecular recognition are also presented. Gold nanotube membranes can perform various separations of ions, organic molecules, proteins, and nucleic acid. This review covers the concepts underlying the separation mechanisms as well as representative applications of gold nanotube membranes in biosensing, catalysis, and biomedical applications. The review concludes with an outlook providing a perspective for further developments and applications of gold nanotube membranes.Leonora Velleman, Joe G. Shapter, Dusan Losi

    Electron transfer through alpha-peptides attached to vertically aligned carbon nanotube arrays: a mechanistic transition

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    This article is part of the Artificial photosynthesis web themed issueThe mechanism of electron transfer in α-aminoisobutyric (Aib) homoligomers is defined by the extent of secondary structure, rather than just chain length. Helical structures (Aib units ≥3) undergo an electron hopping mechanism, while shorter disordered sequences (Aib units <3) undergo an electron superexchange mechanism.Jingxian Yu, Ondrej Zvarec, David M. Huang, Mark A. Bissett, Denis B. Scanlon, Joe G. Shapter and Andrew D. Abel

    Integration of enzyme immobilised single-walled carbon nanotube arrays into microfluidic devices for glucose detection

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    Microfluidic devices for glucose detection have been constructed and developed by integration of glucose oxidase covalently immobilised single-walled carbon nanotube arrays into a poly (dimethylsiloxane)-based microfluidic channel. This microfluidic device was tested for electrochemical glucose detection, and the results showed that the glucose can be detected with a linear response up to a concentration of 5times10-3 mol L-1. Because of the small amounts of fluids and enzyme used in microchannels, this approach offers a number of technical advantages, such as portability, shorter analysis time and lower consumption of expensive analytes.Jingxian Yu, Rudolph Le Roux, Yunfeng Gu, Kamran Yunus, Sinéad Matthews, Joe G. Shapter and Adrian C. Fishe

    The effect of a macrocyclic constraint on electron transfer in helical peptides: a step towards tunable molecular wires

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    Two helical peptides, one constrained by a covalent side-chain staple, exhibit vastly different electronic properties despite adopting essentially the same backbone conformation. High level calculations confirm that these differences are due to the additional backbone rigidity imparted by the macrocyclic constraint.Jingxian Yu, John R. Horsley, Katherine E. Moore, Joe G . Shapter and Andrew D. Abel

    Nanoporous anodic aluminium oxide membranes with layered surface chemistry

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    A new and facile method is described to prepare Janus-like nanoporous anodic aluminium oxide (AAO) membranes with distinctly different internal and external surface chemistry.Abdul Mutalib Md Jani, Emily J. Anglin, Steven J. P. McInnes, Dusan Losic, Joe G. Shapter and Nicolas H. Voelcke

    Self-ordering electrochemistry: a simple approach for engineering nanopore and nanotube arrays for emerging applications

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    In this paper, we present recent work from our group focussed on the fabrication of nanopore and nanotube arrays using self-ordered electrochemistry, and their application in several key areas including template synthesis, molecular separation, optical sensing, and drug delivery. We have fabricated nanoporous anodic aluminium oxide (AAO) with controlled pore dimensions (20–200 nm) and shapes, and used them as templates for the preparation of gold nanorod/nanotube arrays and gold nanotube membranes with characteristic properties such as surface enhanced Raman scattering and selective molecular transport. The application of AAO nanopores as a sensing platform for reflective interferometric detection is demonstrated. Finally, a drug release study on fabricated titania nanotubes confirms their potential for implantable drug delivery applications.Dusan Losic, Leonara Velleman, Krishna Kant, Tushar Kumeria, Karan Gulati, Joe G. Shapter, David A. Beattie and Spomenka Simovi
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