20 research outputs found
Over 'countercurrent-distribution'
No full textAprès quelques remarques générales sur l'extraction par contre-courant, l'auteur décrit principalement la C.C.D. de Craig.
Les différents appareils en usage sont décrits brièvement ainsi que les principes théoriques à la base de cette nouvelle méthode de séparation. Le mode opératoire pour effectuer une séparation par C.C.D. est esquissé.
En conclusion, les avantages et désavantages ainsi que quelques exemples d'application de la C.C.D. sont examinés.After a few general remarks concerning the countercurrent extraction, the author describes principally Craig's C.C.D. The various utilized apparatuses are shortly described as well as the theoretic principles taken as basis for this new separation method. Further the operating process for a separation by C.C.D. is outlined. The author concludes with a survey of the advantages and disadvantages and a few examples of practical applications of this C.C.D. method.Nach einigen allgemeinen Bemerkungen über die Reingewinnung durch Gegenstrom beschreibt Verfasser hauptsächlich Craig's C.C.D. Die verschiedenen zur Anwendung kommenden Apparate werden kurz geschildert sowie die theoretischen Prinzipien dieser neuen Trennungsmethode. Er bringt ebenso das Schema des Verfahrens, das bei solch einer C.C.D. Trennung angewandt wird. Zum Schluss untersucht er die Vor-bzw, Nachteile und einige Anwendungsbeispiele der C.C.D
Letter from Natsue Okine to Seiichi Okine, May 6, 1948 [in Japanese]
No full textA letter from Natue Okine in Itsukaichi, Hiroshima, Japan to her uncle and aunt, Seiichi and Tomeyo Okine. She writes that they are going to start harvesting wheat soon in Japan. She thanks for the cloth that Tomeyo sent to her and informs her that she has made her clothes by using it. In the letter, she expresses her desire to immigrate to the U.S. The letter is resealed with the tape, "OPENED BY MIL. CEN. CIVIL MAILS," and stamped with "C.C.D. J-2903" by the Civil Censorship Detachment. The arrival date of the letter, June 28, 1948, is recorded on the backside of the envelope.The Okine Collection contains materials collected by Seiichi and Tomeyo Okine who were Issei flower growers in Whittier, California. It includes correspondence, photographs, financial documents, and a photo album. A large portion of the collection consists of family correspondence with Seiichi and Tomeyo Okine, including letters from their Nisei children, Masao and Makoto Okine, both soldiers overseas during World War II, to their Issei parents incarcerated in the Rohwer incarceration camp in McGehee, Arkansas. The correspondence also includes letters from their relatives and friends who are former incarcerees in the camps during the war and have “resettled” in Chicago, Illinois as well as letters from the Okines’ family members in Hiroshima, Japan during the Allied occupation of Japan. In addition, the collection includes a family photo album compiled by Dorothy Ai Aoki, a Nisei daughter to the Okines
Letter from Satoko Gyokusen to Mrs. Ayame Okine, July 5, 1948 [in Japanese]
No full textA letter from Satoko Gyokusen in Hiroshima, Japan to her relative, Ayame Okine. She laments the difficulties of her life in post-war Japan. The letter is resealed with the tape, "OPENED BY MIL. CEN. CIVIL MAILS," and stamped with "C.C.D. J-4408" by the Civil Censorship Detachment.The Okine Collection contains materials collected by Seiichi and Tomeyo Okine who were Issei flower growers in Whittier, California. It includes correspondence, photographs, financial documents, and a photo album. A large portion of the collection consists of family correspondence with Seiichi and Tomeyo Okine, including letters from their Nisei children, Masao and Makoto Okine, both soldiers overseas during World War II, to their Issei parents incarcerated in the Rohwer incarceration camp in McGehee, Arkansas. The correspondence also includes letters from their relatives and friends who are former incarcerees in the camps during the war and have “resettled” in Chicago, Illinois as well as letters from the Okines’ family members in Hiroshima, Japan during the Allied occupation of Japan. In addition, the collection includes a family photo album compiled by Dorothy Ai Aoki, a Nisei daughter to the Okines
Letter from Jokichi Yamanaka to Mr. S. Okine, May 17, 1948 [in Japanese]
No full textA letter from Jokichi Yamanaka in Hiroshima, Japan to his brother-in-law, Seiichi Okine. He thanks the Okines for the letter, the tobacco, and ajinomoto brought by the Nakano family. He also thanks Hatsuno Hotty Befu for the gifts. He informs that his daughter, Fumiko, has left for the U.S., but it is not clear when he is going to be permitted to return. The letter is resealed with the tape, "OPENED BY MIL. CEN. CIVIL MAILS," and stamped with "C.C.D. J-2967" by the Civil Censorship Detachment. The arrival date of the letter, June 14, and replied date, 22, are recorded on the backside of the envelope.The Okine Collection contains materials collected by Seiichi and Tomeyo Okine who were Issei flower growers in Whittier, California. It includes correspondence, photographs, financial documents, and a photo album. A large portion of the collection consists of family correspondence with Seiichi and Tomeyo Okine, including letters from their Nisei children, Masao and Makoto Okine, both soldiers overseas during World War II, to their Issei parents incarcerated in the Rohwer incarceration camp in McGehee, Arkansas. The correspondence also includes letters from their relatives and friends who are former incarcerees in the camps during the war and have “resettled” in Chicago, Illinois as well as letters from the Okines’ family members in Hiroshima, Japan during the Allied occupation of Japan. In addition, the collection includes a family photo album compiled by Dorothy Ai Aoki, a Nisei daughter to the Okines
Letter from Toshio Tamaoi [?] to Mrs. Seiichi Okine, December 1947 [in Japanese]
No full textA letter from Toshio Tamaoi in Itsukaichi, Hiroshima, Japan to his uncle, Seiichi Okine. The letter is mailed by Kenjiro Okine. In the letter, he thanks Seiichi for the gifts and laments the high inflation in post-war Japan. He also asks about Kimie Tanimoto who recently left for the U.S. and includes updates on his family: His wife is giving a birth in January and his elderly mother wishes the Okines would return to Japan. The letter is resealed with the tape, "OPENED BY MIL. CEN. CIVIL MAILS," and stamped with "C.C.D. J-4422" by the Civil Censorship Detachment. The arrival date of the letter, February 3, 1948, is recorded on the backside of the envelope.The Okine Collection contains materials collected by Seiichi and Tomeyo Okine who were Issei flower growers in Whittier, California. It includes correspondence, photographs, financial documents, and a photo album. A large portion of the collection consists of family correspondence with Seiichi and Tomeyo Okine, including letters from their Nisei children, Masao and Makoto Okine, both soldiers overseas during World War II, to their Issei parents incarcerated in the Rohwer incarceration camp in McGehee, Arkansas. The correspondence also includes letters from their relatives and friends who are former incarcerees in the camps during the war and have “resettled” in Chicago, Illinois as well as letters from the Okines’ family members in Hiroshima, Japan during the Allied occupation of Japan. In addition, the collection includes a family photo album compiled by Dorothy Ai Aoki, a Nisei daughter to the Okines
Letter from Minoru Sasaki to Mr. S. Okine, September 22, 1947 [in Japanese]
No full textA letter from Minoru Sasaki in Hiroshima, Japan, to his brother-in-law, Seiichi Okine. He thanks Seiichi for the gift, including ajinomoto [monosodium glutamate], sugar, candies, and pencils. He describes the shortages of basic necessities in Japan and states that all children under age 8 do not know the real taste of sugar. He also expresses his relief that they are able to exchange letters and send gifts between two countries again after the war. The letter is resealed with the tape, "OPENED BY MIL. CEN. CIVIL MAILS," and stamped with "C.C.D. J-4435" by the Civil Censorship Detachment. The arrival date of the letter, October 14, 1947, is recorded on the backside of the envelope.The Okine Collection contains materials collected by Seiichi and Tomeyo Okine who were Issei flower growers in Whittier, California. It includes correspondence, photographs, financial documents, and a photo album. A large portion of the collection consists of family correspondence with Seiichi and Tomeyo Okine, including letters from their Nisei children, Masao and Makoto Okine, both soldiers overseas during World War II, to their Issei parents incarcerated in the Rohwer incarceration camp in McGehee, Arkansas. The correspondence also includes letters from their relatives and friends who are former incarcerees in the camps during the war and have “resettled” in Chicago, Illinois as well as letters from the Okines’ family members in Hiroshima, Japan during the Allied occupation of Japan. In addition, the collection includes a family photo album compiled by Dorothy Ai Aoki, a Nisei daughter to the Okines
Letter from Jokichi Yamanaka to Mr. S. Okine, January 20, 1948 [in Japanese]
No full textA letter from Jokichi Yamanaka in Hiroshima, Japan to his brother-in-law and sister-in-law, Seiichi and Tomeyo Okine. Jokichi expresses his gratitude for the gifts that were sent by his niece, Hatsuno Hotty Befu. He explains that while the gifts from Seiichi mainly include clothing, he is often running out of food in Japan and is thus so thankful to receive the gift of food from Hatsuno. Jokichi also updates on the status of his application for a reentry permit to the U.S., assuming that he would be able to return in May or June. The letter is resealed with the tape, "OPENED BY MIL. CEN. CIVIL MAILS," and stamped with "C.C.D. J-2964" by the Civil Censorship Detachment. The arrival date of the letter, February 18, 1948, is recorded on the backside of the envelope.The Okine Collection contains materials collected by Seiichi and Tomeyo Okine who were Issei flower growers in Whittier, California. It includes correspondence, photographs, financial documents, and a photo album. A large portion of the collection consists of family correspondence with Seiichi and Tomeyo Okine, including letters from their Nisei children, Masao and Makoto Okine, both soldiers overseas during World War II, to their Issei parents incarcerated in the Rohwer incarceration camp in McGehee, Arkansas. The correspondence also includes letters from their relatives and friends who are former incarcerees in the camps during the war and have “resettled” in Chicago, Illinois as well as letters from the Okines’ family members in Hiroshima, Japan during the Allied occupation of Japan. In addition, the collection includes a family photo album compiled by Dorothy Ai Aoki, a Nisei daughter to the Okines
Letter from Megumi Sasaki to Mr. S. Okine, January 22, 1948 [in Japanese]
No full textA letter from Megumi Sasaki in Hiroshima, Japan to Seiichi and Tomeyo Okine. Megumi introduces himself as though he has never met them nor been in contact with them before. He is a son of Matsuyo Sasaki and a brother of Minoru Sasaki. He explains that he was drafted into the Japanese military in 1944 and finally returned to Hiroshima, Japan in 1947. When he returned he found that his wife and daughters had survived with some injuries, but that his home in Hiroshima has been destroyed by the atomic bomb. He then explains about the resulting hardships in post-war Japan, renting a room in a barrack, and lacking adequate food. The envelope is resealed with the tape, "OPENED BY MIL. CEN. CIVIL MAILS"and stamped with "C.C.D. J-2916" by the Civil Censorship Detachment. The arrival date of the letter, February 18, 1948, and replied date, March 1, are recorded on the backside of the envelope.The Okine Collection contains materials collected by Seiichi and Tomeyo Okine who were Issei flower growers in Whittier, California. It includes correspondence, photographs, financial documents, and a photo album. A large portion of the collection consists of family correspondence with Seiichi and Tomeyo Okine, including letters from their Nisei children, Masao and Makoto Okine, both soldiers overseas during World War II, to their Issei parents incarcerated in the Rohwer incarceration camp in McGehee, Arkansas. The correspondence also includes letters from their relatives and friends who are former incarcerees in the camps during the war and have “resettled” in Chicago, Illinois as well as letters from the Okines’ family members in Hiroshima, Japan during the Allied occupation of Japan. In addition, the collection includes a family photo album compiled by Dorothy Ai Aoki, a Nisei daughter to the Okines
Letter from Haruto Okine to Mr. Seichi Okine, January 29, 1948 [in Japanese]
No full textA letter from Haruto Okine in Hiroshima, Japan, to his uncle, Seiichi Okine. The letter is mailed by Naoji Okine, Seiichi's brother. In the letter, Haruto thanks Seiichi Okine for the gifts and gives congratulations to Masao Okine on his new baby. He hopes that Seiichi will return to Japan someday when Japan rebuilds from the war damage. He also requests some old winter clothes for his children to wear as it is difficult to attain basic necessities in Japan after the war. The letter is resealed with the tape, "OPENED BY MIL. CEN. CIVIL MAILS," and stamped with "C.C.D. J-4436" by the Civil Censorship Detachment. The arrival date of the letter, February 28, 1948, is recorded on the backside of the envelope.The Okine Collection contains materials collected by Seiichi and Tomeyo Okine who were Issei flower growers in Whittier, California. It includes correspondence, photographs, financial documents, and a photo album. A large portion of the collection consists of family correspondence with Seiichi and Tomeyo Okine, including letters from their Nisei children, Masao and Makoto Okine, both soldiers overseas during World War II, to their Issei parents incarcerated in the Rohwer incarceration camp in McGehee, Arkansas. The correspondence also includes letters from their relatives and friends who are former incarcerees in the camps during the war and have “resettled” in Chicago, Illinois as well as letters from the Okines’ family members in Hiroshima, Japan during the Allied occupation of Japan. In addition, the collection includes a family photo album compiled by Dorothy Ai Aoki, a Nisei daughter to the Okines
12-h clock regulation of genetic information flow by XBP1s
No full text© The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Pan, Y., Ballance, H., Meng, H., Gonzalez, N., Kim, S., Abdurehman, L., York, B., Chen, X., Schnytzer, Y., Levy, O., Dacso, C. C., McClung, C. A., O'Malley, B. W., Liu, S., & Zhu, B. 12-h clock regulation of genetic information flow by XBP1s. Plos Biology, 18(1), (2020): e3000580, doi:10.1371/journal.pbio.3000580.Our group recently characterized a cell-autonomous mammalian 12-h clock independent from the circadian clock, but its function and mechanism of regulation remain poorly understood. Here, we show that in mouse liver, transcriptional regulation significantly contributes to the establishment of 12-h rhythms of mRNA expression in a manner dependent on Spliced Form of X-box Binding Protein 1 (XBP1s). Mechanistically, the motif stringency of XBP1s promoter binding sites dictates XBP1s’s ability to drive 12-h rhythms of nascent mRNA transcription at dawn and dusk, which are enriched for basal transcription regulation, mRNA processing and export, ribosome biogenesis, translation initiation, and protein processing/sorting in the Endoplasmic Reticulum (ER)-Golgi in a temporal order consistent with the progressive molecular processing sequence described by the central dogma information flow (CEDIF). We further identified GA-binding proteins (GABPs) as putative novel transcriptional regulators driving 12-h rhythms of gene expression with more diverse phases. These 12-h rhythms of gene expression are cell autonomous and evolutionarily conserved in marine animals possessing a circatidal clock. Our results demonstrate an evolutionarily conserved, intricate network of transcriptional control of the mammalian 12-h clock that mediates diverse biological pathways. We speculate that the 12-h clock is coopted to accommodate elevated gene expression and processing in mammals at the two rush hours, with the particular genes processed at each rush hour regulated by the circadian and/or tissue-specific pathways.This study was supported by the American Diabetes Association junior faculty development award 1-18-JDF-025 to B.Z., by funding from National Institute of Health HD07879 and 1P01DK113954 to B.W.O, by funding from National Science Foundation award 1703170 to C.C.D. and B.Z., and by funding from Brockman Foundation to C.C.D and B.W.O. This work was further supported by the UPMC Genome Center with funding from UPMC’s Immunotherapy and Transplant Center. This research was supported in part by the University of Pittsburgh Center for Research Computing through the resources provided. Research reported in this publication was further supported by the National Institute of Diabetes And Digestive And Kidney Diseases of the National Institutes of Health under award number P30DK120531 to Pittsburgh Liver Research Center, in which both S.L. and B.Z. are members. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript
