323,522 research outputs found
Jobling, E M, VX25508
No full textThis record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/395295Surname: JOBLING. Given Name(s) or Initials: E M. Military Service Number or Last Known Location: VX25508. Missing, Wounded and Prisoner of War Enquiry Card Index Number: 42557.229536
Item: [2016.0049.27588] "Jobling, E M, VX25508
A parametric analysis of a tunnel climatic prediction and planning model
No full textI.S. Lowndes, Z.Y. Yang, S. Jobling, C. Yate
Seasonal effects of treated sewage effluents upon the reproduction and development of European freshwater molluscs
No full textThis thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The most widespread evidence of environmental endocrine disruption in aquatic wildlife is from the feminising effects of oestrogenic endocrine disrupting compounds. However, very little is known of the effects of these chemicals (and others) upon freshwater molluscs found in our river and lakes. This thesis aimed at evaluating the effects of treated sewage effluent upon the reproductive and developmental cycle of a range of commonly found European freshwater gastropod molluscs. Initial mesocosm experiments were undertaken to test a range of mollusc species for their the suitability to the experimental system, and to test adult snails for their reproductive and developmental responses during spring to summer time. With suitable species chosen, P.corneus, a pulmonate species (sequential hermaphrodite), and V. Viviparus a prosobranch species (dioeious; separate sexes), full reproductive output was assessed over summertime and into autumn, along with developmental responses amongst the F1 generation of snails.
My results suggest that the affects of effluent upon the reproductive and developmental cycle of P. corneus are strongly mitigated by both day length and water temperature (day length is most important with V. viviparus); results are sensitive to seasonal effects. However, at the peak of reproduction mid summer, P. corneus produced significantly more egg masses in effluent (100% effluent particularly), and more than one parameter of reproduction was affected. Egg masses were significantly smaller in effluent and contained significantly fewer eggs per mass. Further, there were indications that total reproductive output was increased (100% effluent significantly) in effluent compared to the river water control. In the prosobranch species V. viviparus results were less convincing, however, in 100% effluent a second reproductive peak occurred that was not seen in river water. Further, in both species there was a failure of certain reproductive parameters to observe the normal seasonal decline towards winter. In P. corneus there was a failure to stop producing egg masses in effluent, in V. viviparus the second reproductive peak in effluent could also threaten their survival with winter approaching. Developmental effects in the F1 generation were the subject of preliminary investigations, however, F1 V. viviparus demonstrated a higher than normal incidence of intersex (male and female developmental features) in effluent, and P. corneus appeared to have disturbed reproductive function (disturbance of both male and female reproductive function in the ovotestis).
Therefore, both of these species of molluscs demonstrated that they are sensitive to the effects of effluent in mesocosm studies. However, we need to understand much more about their responses to effluent; in particular whether these effects could have repercussions for wild mollusc populations, and whether these effects could occur over more than one generation of snail threatening the survival of wild populations of molluscs
An active microelectrode array to detect extracellular nervous activity
No full textThe detection of extracellular potentials in nervous tissue using conventional methods has many limitations. In particular, it is extremely difficult to detect potentials simultaneously at more than two or three sites on one tissue preparation, and elaborate precautions are needed to reduce electrostatic interference. This thesis describes the development of an active array of nine microelectrodes with buffer amplifiers for detecting extracellular potentials. Integrated circuit technology has been used, enabling the microelectrodes and buffer amplifiers to be made on the same silicon substrate at different stages of one fabrication process. The characteristics of the interface of the evaporated gold microelectrodes and physiological saline were measured, and it was found that the interface impedance was higher than that reported for other gold electrodes. A variety of surface coatings to insulate and passivate the integrated circuit buffer amplifiers were investigated so that they could be operated submerged in saline. Connections to the buffer amplifiers were made using low resistance diffused layers coated with thermally grown silicon dioxide. Photoresist was used to insulate other parts of the circuit. The integrated buffer amplifiers were formed by using MS transistors in the source follower configuration. Each microelectrode was part of the gate electrode of an underlying transistor. The micrcroectrode array was used with off-chip voltage amplifiers and a multiplexer to permit a simultaneous display of the potentials at each electrode. In experiments with nervous tissue, results which would have been almost impossible to obtain with conventional electrodes were achieved. Experiments showed that the threshold voltages of the M S transistors in the array changed slightly during their operation in saline, but the devices performed satisfactorily throughout several hundred hours of continuous operation.</p
Addendum to Kirwan et al. (2016, Zootaxa 4121 (1): 89 – 94)
No full textDavid, Normand, Gregory, Steven M. S., Kirwan, Guy M., Jobling, James A., Steinheimer, Frank D., Brito, Guilherme Renzo Rocha (2017): Addendum to Kirwan et al. (2016, Zootaxa 4121 (1): 89 – 94). Zootaxa 4216 (3): 299-300, DOI: 10.5281/zenodo.23185
Reproductive effects in two species of native freshwater gastropod mollusc exposed to 17β-oestradiol or an environmentally relevant mixture of oestrogenic chemicals in outdoor mesocosms
No full textThis thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Recent evidence suggests that molluscs may be sensitive to the effects of endocrine
disrupting chemicals (EDCs) in a similar manner to vertebrates, such as fish. Despite this
(with the exception of TBT-induced imposex in marine gastropods), molluscs have been
largely overlooked in the field of endocrine disruption. Life-cycle studies were conducted
in which two species of native UK freshwater gastropod molluscs (the hermaphrodite
Planorbarius corneus and the gonochorist Viviparus viviparus) were exposed to either
17β-oestradiol or environmentally relevant mixtures of chemicals known to be oestrogenic
to vertebrates and to be present in UK treated sewage effluents (TSE) and rivers. Adult
snails were exposed for four months in outdoor mesocosms, fed by river water, over the
spring and summer (breeding season) in order to examine effects on reproductive output,
growth and mortality. Furthermore, offspring (F1s) were also developmentally exposed
over the same period. F1 juvenile snails were then depurated in river water for nine months
(over winter) after which time their growth, survival, and reproductive success were
measured in further un-dosed river water mesocosm studies in the following
spring/summer. Histopathology was used to determine immediate effects of chemical
exposure on adult and F1 snails’ reproductive health. Histopathology was also used to
determine long lasting effects of chemical exposure on depurated F1s. Exposure to
oestrogenic chemicals resulted in a range of effects, including modulated fecundity and
growth in F0 adults, to retardation of growth, sexual development and fecundity in
developmentally exposed F1s. Exposure to mixtures of oestrogenic chemicals also resulted
in possible modulation of the immune system, resulting in increased parasitism and over
winter mortality of exposed F1s compared to snails exposed to river water alone.
Differences in sensitivity and response to exposure between the two species and the
generations were also observed
Down Syndrome Across the Life Span
No full textBeyond the myths: representing people with Down syndrome / Jan Gothard -- Learning in young children with Down syndrome: public perceptions, empirical evidence / Jennifer G. Wishart -- Self-regulation in children and young people with Down syndrome / Sheila Glenn and Cliff Cunningham -- What matters most? A reflection on a quarter century of early childhood intervention / Robin Treloar and Susan Cairns -- Making inclusion work: improving educational outcomes for students with Down syndrome in the regular classroom / Loretta R. Giorcelli -- Cognitive development and education: perspectives on Down syndrome from a twenty-year research programme / Susan Buckley and Gillian Bird -- Broadening approaches to literacy education for young adults with Down syndrome / Christina E. van Kraayenoord ... [et al.] -- Numeracy and money management skills in young adults with Down syndrome / Sandra Bochner ... [et al.] -- Life styles of adults with Down syndrome living at home / Anne Jobling and Monica Cuskelly -- Some studies involving individuals with Down syndrome and their relevance to a quality of life model / Verity Bottroff ... [et al.] -- From autonomy to work placement / Anna Contardi -- An appreciative inquiry about adults with Down syndrome / Susanne Muirhead -- Multiple perspectives of family life / Monica Cuskelly ... [et al.] -- Verbal-motor behaviour in persons with Down syndrome / Brian K.V. Maraj ... [et al.]
The mistaken manakin: a new genus-group name for Parus pipra Linnaeus, 1758 (Aves: Passeriformes: Pipridae)
No full textKirwan, Guy M., David, Normand, Gregory, Steven M. S., Jobling, James A., Steinheimer, Frank D., Brito, Guilherme Renzo Rocha (2016): The mistaken manakin: a new genus-group name for Parus pipra Linnaeus, 1758 (Aves: Passeriformes: Pipridae). Zootaxa 4121 (1): 89-94, DOI: 10.11646/zootaxa.4121.1.
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