10 research outputs found
Fine-grained entity typing system - design and analysis
Named entity recognition (NER) is a natural language processing (NLP) task that involves identifying mentions (spans of text) denoting entities in a given text document and assigning them a semantic category/type from a given taxonomy. It is considered to be one of the fundamental tasks in NLP and forms the basis for higher level understanding. In this thesis, we deal with fine-grained entity type recognition, which is a variant of the classic NER task where the usual types are sub-divided into fine-grained types. We show that the current approaches, which address this problem using only local context, are insufficient to completely address the problem. We systematically identify the fundamental challenges and misconceptions that underlie the assumptions, approaches and evaluation methodologies of this task and propose improvements and alternatives. We do this by first analyzing the role of context and background knowledge in the task of fine-grained entity typing. Second, we introduce a modular architecture for fine-grained typing of entities and show that a rather simple instantiation of these modules reaches the state-of-the-art performance.Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2020-05-01The student, Pavankumar Reddy Muddireddy, accepted the attached license on 2018-04-23 at 17:30.The student, Pavankumar Reddy Muddireddy, submitted this Thesis for approval on 2018-04-23 at 17:42.This Thesis was approved for publication on 2018-04-24 at 09:20.DSpace SAF Submission Ingestion Package generated from Vireo submission #12436 on 2018-08-31 at 17:21:20Made available in DSpace on 2018-09-04T20:36:52Z (GMT). No. of bitstreams: 2
MUDDIREDDY-THESIS-2018.pdf: 446805 bytes, checksum: 30dc454cac28cfff02a4762ba75d774a (MD5)
LICENSE.txt: 4224 bytes, checksum: b8203e25ef7f7ebfd07f9694a6abae27 (MD5)
Previous issue date: 2018-04-24Embargo set by: Seth Robbins for item 107298
Lift date: 2020-09-04T20:37:00Z
Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD systemEmbargo set by: Seth Robbins for item 107298
Lift date: 2020-09-04T20:42:08Z
Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD systemU of I Only Restriction Lifted for Item 107298 on 2020-09-05T09:15:29Z
QTL Mapping and Identification of QTLs Linked to Yield and Yield Attributing Traits in Chickpea
Influence of ZnO and TiO2 nanoparticles in the establishment and growth of in vitro callus cultures of coffee
Comparative genomic analysis and phylogeny of NAC25 gene from cultivated and wild Coffea species
Coffee is a high value agricultural commodity grown in about 80 countries. Sustainable coffee cultivation is hampered by multiple biotic and abiotic stress conditions predominantly driven by climate change. The NAC proteins are plants specific transcription factors associated with various physiological functions in plants which include cell division, secondary wall formation, formation of shoot apical meristem, leaf senescence, flowering embryo and seed development. Besides, they are also involved in biotic and abiotic stress regulation. Due to their ubiquitous influence, studies on NAC transcription factors have gained momentum in different crop plant species. In the present study, NAC25 like transcription factor was isolated and characterized from two cultivated coffee species, Coffea arabica and Coffea canephora and five Indian wild coffee species for the first time. The full-length NAC25 gene varied from 2,456 bp in Coffea jenkinsii to 2,493 bp in C. arabica. In all the seven coffee species, sequencing of the NAC25 gene revealed 3 exons and 2 introns. The NAC25 gene is characterized by a highly conserved 377 bp NAM domain (N-terminus) and a highly variable C terminus region. The sequence analysis revealed an average of one SNP per every 40.92 bp in the coding region and 37.7 bp in the intronic region. Further, the non-synonymous SNPs are 8-11 fold higher compared to synonymous SNPs in the non-coding and coding region of the NAC25 gene, respectively. The expression of NAC25 gene was studied in six different tissue types in C. canephora and higher expression levels were observed in leaf and flower tissues. Further, the relative expression of NAC25 in comparison with the GAPDH gene revealed four folds and eight folds increase in expression levels in green fruit and ripen fruit, respectively. The evolutionary relationship revealed the independent evolution of the NAC25 gene in coffee
Table_5_Comparative genomic analysis and phylogeny of NAC25 gene from cultivated and wild Coffea species.DOCX
Coffee is a high value agricultural commodity grown in about 80 countries. Sustainable coffee cultivation is hampered by multiple biotic and abiotic stress conditions predominantly driven by climate change. The NAC proteins are plants specific transcription factors associated with various physiological functions in plants which include cell division, secondary wall formation, formation of shoot apical meristem, leaf senescence, flowering embryo and seed development. Besides, they are also involved in biotic and abiotic stress regulation. Due to their ubiquitous influence, studies on NAC transcription factors have gained momentum in different crop plant species. In the present study, NAC25 like transcription factor was isolated and characterized from two cultivated coffee species, Coffea arabica and Coffea canephora and five Indian wild coffee species for the first time. The full-length NAC25 gene varied from 2,456 bp in Coffea jenkinsii to 2,493 bp in C. arabica. In all the seven coffee species, sequencing of the NAC25 gene revealed 3 exons and 2 introns. The NAC25 gene is characterized by a highly conserved 377 bp NAM domain (N-terminus) and a highly variable C terminus region. The sequence analysis revealed an average of one SNP per every 40.92 bp in the coding region and 37.7 bp in the intronic region. Further, the non-synonymous SNPs are 8-11 fold higher compared to synonymous SNPs in the non-coding and coding region of the NAC25 gene, respectively. The expression of NAC25 gene was studied in six different tissue types in C. canephora and higher expression levels were observed in leaf and flower tissues. Further, the relative expression of NAC25 in comparison with the GAPDH gene revealed four folds and eight folds increase in expression levels in green fruit and ripen fruit, respectively. The evolutionary relationship revealed the independent evolution of the NAC25 gene in coffee.</p
The RNA workbench: best practices for RNA and high-throughput sequencing bioinformatics in Galaxy
RNA-based regulation has become a major research topic in molecular biology. The analysis of epigenetic and expression data is therefore incomplete if RNA-based regulation is not taken into account. Thus, it is increasingly important but not yet standard to combine RNA-centric data and analysis tools with other types of experimental data such as RNA-seq or ChIP-seq. Here, we present the RNA workbench, a comprehensive set of analysis tools and consolidated workflows that enable the researcher to combine these two worlds. Based on the Galaxy framework the workbench guarantees simple access, easy extension, flexible adaption to personal and security needs, and sophisticated analyses that are independent of command-line knowledge. Currently, it includes more than 50 bioinformatics tools that are dedicated to different research areas of RNA biology including RNA structure analysis, RNA alignment, RNA annotation, RNA-protein interaction, ribosome profiling, RNA-seq analysis and RNA target prediction. The workbench is developed and maintained by experts in RNA bioinformatics and the Galaxy framework. Together with the growing community evolving around this workbench, we are committed to keep the workbench up-to-date for future standards and needs, providing researchers with a reliable and robust framework for RNA data analysis. Availability: The RNA workbench is available at https://github.com/bgruening/galaxy-rna-workbench.© The Author(s) 201
