29,240 research outputs found
Molecular perspective of protein-ligand selectivity in host and parasitic plants
No full textSubmission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2024-12-01The student, Jiming Chen, accepted the attached license on 2022-09-26 at 17:06.The student, Jiming Chen, submitted this Dissertation for approval on 2022-09-26 at 17:21.This Dissertation was approved for publication on 2022-10-04 at 13:56.DSpace SAF Submission Ingestion Package generated from Vireo submission #18504 on 2023-04-12 at 08:10:28Witchweed, or Striga hermonthica, is a parasite that destroys $10 billion worth of crops annually. It detects its hosts by detecting strigolactone hormone exuded into the soil by its hosts and using it as a germination stimulant, after which it attaches itself to the root of the host crop and absorbs its nutrients. Despite high sequence, structure, and binding site conservation across different plant species, one strigolactone receptor found in witchweed, ShHTL7 uniquely exhibits picomolar sensitivity to strigolactones, compared to micromolar levels observed in homologs. Previously, the prevailing hypothesis was that this million-fold sensitivity difference is the result of its larger binding pocket volume compared to other receptors, however, this does not account for the dynamics of each of the mechanistic steps of strigolactone signaling. The early steps of strigolactone signaling are binding of the substrate to the receptor, enzymatic hydrolysis of the substrate by the receptor, a conformational change of the receptor to its active state, and association of the active-conformation receptor to its signaling partner. Using a combination of long-timescale molecular dynamics (~3 ms aggregate), QM/MM, and umbrella sampling simulations, we have elucidated mechanistic details of the strigolactone signaling process at atomic resolution in AtD14, a strigolactone receptor found in the non-parasitic plant Arabidopsis thaliana, and ShHTL7. These mechanistic details indicate that while ShHTL7 is more binding with the strigolactone substrate than AtD14, signaling steps that occur after substrate hydrolysis are also key drivers of the selectivity in strigolactone signaling between parasite and host. These mechanistic insights have the potential to aid the design of selective control agents to control witchweed with minimal effect on surrounding host crops
Systematically Challenging Three Prevailing Notions About Entropy and Life
No full textThis article reveals the original, fundamental, and uncontroversial nature of entropy and systematically challenges three
notions prevailing in diverse disciplines: (1) entropy is a measure of disorder; (2) life relies on negative entropy; (3)
many systems tend to become increasingly disordered due to the second law of thermodynamics. The challenge is
supported by numerous compelling facts and the modern explanation of the second law of thermodynamics. The
challenge, if widely accepted, could facilitate the eradication of the entrenched misleading effects of the three
misconceptions in diverse disciplines and facilitate relevant research and education on complexity, entropy, disorder,
order, evolution, life, and thermodynamics
The Promise of Beijing: Evaluating the Impact of the 2008 Olympic Games on Air Quality
No full textTo prepare for the 2008 Olympic Games, China adopted a number of radical measures to improve air quality. Using officially reported air pollution index (API) from 2000 to 2009, we show that these measures improved the API of Beijing during and after the Games, but 60% of the effect faded away by the end of October 2009. Since the credibility of API data has been questioned, an objective and indirect measure of air quality at a high spatial resolution – aerosol optimal depth (AOD), derived using the data from the NASA satellites – was analyzed and compared with the API trend. The analysis confirms that the improvement was real but temporary and most improvement was attributable to plant closure and traffic control. Our results suggest that it is possible to achieve real environmental improvement in an authoritarian regime but the magnitude of the effect and how long it lasts depend on the political motivation behind the policy interventions.
Chen Chen, 42nd Annual ODU Literary Festival
No full textChen Chen is the author of When I Grow Up I Want to Be a List of Further Possibilities (BOA Editions, 2017), which was long-listed for the National Book Award and won the Thom Gunn Award, among other honors. Bloodaxe Books published a UK edition in June. He is also the author of four chapbooks, most recently You MUST Use the Word Smoothie (Sundress Publications, 2019) and Gesundheit! (in collaboration with Sam Herschel Wein and forthcoming from Glass Poetry Press, fall 2019). His work appears in many publications, including Poem-a-Day, The Massachusetts Review, The Best American Poetry, and The Best American Nonrequired Reading. He has received a Pushcart Prize and fellowships from Kundiman and the National Endowment for the Arts. He holds an MFA from Syracuse University and a PhD from Texas Tech University. He teaches at Brandeis University as the Jacob Ziskind Poet-in-Residence and co-runs the journal, Underblong. He lives in Waltham, Massachusetts, with his partner, Jeff Gilbert, and their pug, Mr. Rupert Gile
Supporting data used in the paper: Xi Chen, 2020, The LMARS based shallow-water dynamical core on generic gnomonic cubed-sphere geometry
No full text# Simulation results of the unstaggered shallow water model
This repository contains the supporting data used in the paper: Xi Chen, 2020, The LMARS based shallow‐water dynamical core on generic gnomonic cubed‐sphere geometry, DOI: 10.1029/2020MS002280
Organization of the repository:
The tar archive with this data submission has a:
doc directory contains a README.md with information regarding naming conventions to label the model configurations for a shallow water test simulation. Additional information can also be found in README.md. Table 4 in the paper provides additional details.
The data directory contains the supporting data files (NetCDF format).Disclaimer: "This was prepared by Xi Chen under award NA18OAR4320123 from the National Oceanic and Atmospheric Administration, U.S. Department of Commerce. The statements, findings, conclusions, and recommendations are those of the author(s) and do not necessarily reflect the views of the National Oceanic and Atmospheric Administration, or the U.S. Department of Commerce.
Artimpaza brevilineata Tian & Chen, 2012 in Tian, Chen & Li 2012
No full textArtimpaza brevilineata Tian & Chen, 2012 in Tian, Chen & Li, 2012: 43, figs. 1–9. (Figs. 28a, b) Type locality: China, Yunnan, Pu’er City, Yutang. Gender: female. Date collected: 2011.V.25 (2010.V.25, in the original description, is incorrect). Collector: Li-Chao TIAN & Gui-Qiang HUANG. Paratypes: 1 female, China, Yunnan, Lincang City, 1980.VI.1, Fen LIU leg. Remarks: In the original description, the type locality is “ Yunnan, Jinghong” while it is “ Yunnan, Yutang” according to the label. “Yutang” is actually in Pu’er, not Jinghong. The first author described the type locality by mistake. In the original description, the collector was only listed as Li-Chao TIAN, which was a mistake.Published as part of Li, Zhu & Chen, Li, 2020, Primary types of longhorned beetles (Coleoptera, Cerambycidae, Vesperidae and Disteniidae) of Southwest University (SWU), pp. 25-46 in Zootaxa 4718 (1) on page 33, DOI: 10.11646/zootaxa.4718.1.2, http://zenodo.org/record/360220
Author contributions
No full textPlease browse the "Files" tag to access the appendix specifying the author - Chen Hsi Tsai's contributions to the seven papers included in the thesis
Ying Chen\u27s Impressions of Summer
No full textChapbook of narrative/personal poems by Ying Chen originally published by Finishing Line Press in 2013. Translated from the French by Peter Schulman, ODU Professor of French and International Studies.https://digitalcommons.odu.edu/worldlanguages_books/1016/thumbnail.jp
《在中法之间 — 陈伟农的艺术体验》 Zai Zhong Fa zhi jian: Chen Weinong de yishu tijian / “Between China and France. The Artistic Experience of Chen Weinong”
No full textThe author analizes the artistic production of the Chinese contemporary artist Chen Weinong, who has travelled between China and France for more ten years. In his ink paintings and calligraphies, Chen Weinong reflects the essence of both Western and Eastern cultures, succeeding in refreshing the ancient tradition as well as blazing new trails in Chinese art
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