33 research outputs found
Policy application to RTI pooler networks for optimized relocation planning: Optimizing RTI pooling management for reducing operational costs and increasing sustainability in supply chains
No full textIn this thesis, the optimization of inventory management within RTI pooler networks is considered. The inventory management by RTI poolers consists of the network configurations on which the network relies, as well as the relocation schedule of RTI poolers that determines the functionality of the system.Engineering and Policy Analysi
Biographical sketch of Levi Myers ...
No full textAutographed letter of the author inserted.Mode of access: Internet
Communicative Practices in Nurse vs. GP-Led Telephone Triage: A Comparative Investigation
No full textA pre–post intervention study of pulmonary rehabilitation for adults with post-tuberculosis lung disease in Uganda
No full textRupert Jones,1 Bruce J Kirenga,2 Wincelsas Katagira,2 Sally J Singh,3 Jill Pooler,4 Alphonse Okwera,2 Richard Kasiita,5 Doyo G Enki,6 Siobhan Creanor,6 Andy Barton4 1Population Studies and Clinical Trials, Peninsula Schools of Medicine and Dentistry, Plymouth University, Plymouth, UK; 2Population Studies and Clinical Trials, Makerere Lung Institute, Makerere University College of Health Sciences, Mulago Hospital, Kampala, Uganda; 3Cardio-Respiratory Directorate, University Hospitals of Leicester NHS Trust, Leicester, 4Population Studies and Clinical Trials, Peninsula Schools of Medicine and Dentistry, Plymouth University, Plymouth, UK; 5Department of Physiotherapy, Mulago Hospital, Kampala, Uganda; 6Medical Statistics, Peninsula Schools of Medicine and Dentistry, Plymouth University, Plymouth, UK Setting: The study was conducted at Mulago Hospital, Kampala, Uganda.Objective: As chronic respiratory disease (CRD) is a huge, growing burden in Africa, with few available treatments, we aimed to design and evaluate a culturally appropriate pulmonary rehabilitation (PR) program in Uganda for people with post-tuberculosis lung disorder (p-TBLD).Design: In a pre–post intervention study, a 6-week, twice-weekly PR program was designed for people with p-TBLD. Outcome measures included recruitment, retention, the Clinical COPD Questionnaire (CCQ), tests of exercise capacity, and biometrics. Given this was a developmental study, no formal statistical significance testing was undertaken.Results: In all, 34 participants started PR and 29 (85%) completed all data collection. The mean age of the 29 participants was 45 years, and 52% were female. The mean (95% confidence interval) CCQ score at baseline was 1.8 (1.5, 2.0), at the end of PR was 1.0 (0.8, 1.2), and at 6 weeks after the end of PR was 0.8 (0.7, 1.0). The Incremental Shuttle Walking Test (ISWT) was 299 m (268.5, 329.4) at baseline, 377 (339.6, 413.8) at the end of PR, and 374 (334.2, 413.5) at 6 weeks after the end of PR. Improvements were seen in measures of chest pain; 13/29 (45%) participants reported chest pain at baseline but only 7/29 (24%) at the end of PR, and in those with persistent pain, the mean pain scores decreased. Mild hemoptysis was reported in 4/29 (17%) participants at baseline and in 2/29 (7%) at the end of PR.Conclusion: PR for people with p-TBLD in Uganda was feasible and associated with clinically important improvements in quality of life, exercise capacity, and respiratory outcomes. PR uses local resources, requires little investment, and offers a new, sustainable therapy for p-TBLD in resource-limited settings. With the rising global burden of CRD, further studies are needed to assess the value of PR in p-TBLD and other prevalent forms of CRD. Keywords: tuberculosis, exercise training, self-management, nonpharmacological intervention 
"The history of a poet's mind" : the autobiographical writing of Henry James, Siegried Sassoon and Dorothy Richardson
No full textThis thesis considers the method and motivation of the self-representation of the author as a literary artist-hero in the autobiographical sequences of Henry James, Siegfried Sassoon and Dorothy Richardson, and in particular it traces the parallels between these texts and the model of the German Romantic Künstlerroman. In so doing, I show that the tropes and themes of the Künstlerroman genre assist the autobiographers’ representation of artistic identity in a period of increasingly fragmented conceptions of selfhood. Underlying my hermeneutic approach is the concept of literary inheritance as a movement from tradition to individual innovation, reflected in a motif of the parent-child relationship, and in autobiographical tropes, and language usage. These are traced in each text under review and weave together issues of historical context, genre innovation, and literary self-invention. The three authors demonstrate a shared preoccupation with the role of life experience in the creation of art, and with the interconnection of personality and style. This study concludes that an understanding of the relation of the artist to the literary account of their own life creates a challenge to poststructuralist perceptions of the gap between author and text. The introduction outlines the particular relevance of the historical moment between 1910 and 1920 for the study of these autobiographical works. Chapter one presents my methodological approach in relation to pertinent autobiography theory and provides an overview of the Künstlerroman genre, its transference from German to English literature, and the changing intentions of autobiographers between the nineteenth and twentieth centuries as demonstrated in Edmund Gosse’s Father and Son. Chapters two and three consider James’s A Small Boy and Others, Notes of a Son and Brother and The Middle Years, while chapters four and five examine Sassoon’s The Old Century and Seven More Years, The Weald of Youth and Siegfried’s Journey. These four chapters analyse the narrative technique employed in each case and its intimate relationship with the authors’ self-image. Chapter six focuses on the stylistic innovations of Richardson’s Pilgrimage. The conclusion then addresses the idea that ‘style is the man himself’, that a second ‘portrait’ can be read in the formal choices made in the text’s construction, and, as a result, considers the particular role of autobiographical writing for our reading of the artist.EThOS - Electronic Theses Online ServiceGBUnited Kingdo
Town of Cumberland Town Council Special Meeting May 21, 2007
No full textTown of Cumberland Town Council Special Meeting May 21, 2007 is the complete packet for the Cumberland Town Council special meeting for May 21, 2007, and includes the minutes of the Town Council meetings of April 23, 2007 and May 14, 2007. Agenda items include: 07 – 058. To hold public hearing to consider and act on a Victualer\u27s License, Class XI Restaurant/Lounge license, and Special Amusement Permit for Bittersweet, Inc., d/b/a The Slow Bell Cafe, 2 Walker Road, Chebeague Island, for the month of June, 2007. 07 – 059. To authorize the Town Manager to enter into a EWP Project Agreement with the Natural Resources Conservation Service and to accept surety from Rod and Jill Pooler, 218 Range Road, for repairs to their property caused by the May, 2006, storm event. 07 – 060. To hold public hearing to consider and act on the Assignment and Bill of Sale to the Town of Chebeague Island for the MDOT Cousins Island Blanchard lot. 07 – 061. To hold public hearing to consider and act on Service Agreements between the Town of Cumberland and the Town of Chebeague Island for the following services: Tax Bills FY \u2708 Town Clerk Services Mooring and Shellfish Fees Building Permits Equipment Trade Municipal Releas
High-Resolution Melting Analysis Enables Efficient Detection and Differentiation of Two Boxwood Blight Pathogens by qPCR Assays
No full textBoxwood blight is a devastating disease caused by the fungal pathogens Calonectria henricotiae (Che) and C. pseudonaviculata (Cps). Identification and detection of these pathogens from infected plant material could play a significant role in breeding and selection of resistant cultivars and development of disease management strategies in the ornamental nursery industry. We designed a simple, single-tube method for extraction of PCR-amplifiable DNA from boxwood leaves and cultures of the Calonectria pathogens. Previously developed fungal-specific primers based on histone and calmodulin regions were used to detect and distinguish between Che and Cps using real-time PCR and high-resolution melting (HRM) analysis, with discernable melting temperature differences of 0.5°C between amplified products. Here, we describe a single-tube acetone-based DNA extraction method and qPCR-HRM assay targeting single nucleotide polymorphisms within the calmodulin and histone H3 DNA regions as a fast and highly sensitive molecular method to detect and differentiate between Che and Cps species directly from plant tissue. [Figure: see text] Copyright © 2022 The Author(s). This is an open access article distributed under the CC BY-NC-ND 4.0 International license
Erratum: The Perfect Storm? COVID-19 and Substance Use amongst Social Work Students in the USA (The British Journal of Social Work (2021) DOI: 10.1093/bjsw/bcab192)
No full textIn the originally published manuscript, the affiliation for co-author Dr Arati Maleku contained an error. This should read: College of Social Work instead of College only. This error is now corrected in the article online
How patient participation was used to develop a questionnaire that is fit for purpose for assessing quality of life in severe asthma
No full textAbstract Background Previous research shows that existing asthma quality of life questionnaires fail to measure the burden of oral corticosteroids that can be used to treat severe asthma, and are therefore not fit for purpose for severe asthma according to the USA’s Food and Drug Administration (FDA) criteria for content validity. Patient input and documentation of that input is key to achieving content validity according to FDA guidelines. This paper describes the process of constructing a new questionnaire to measure the burden of asthma symptoms and burden of treatment in severe asthma, using criteria specified by the FDA. Methods A draft severe asthma questionnaire (SAQ) was constructed using qualitative input from severe asthma patients who took part in an earlier study. The aim of this study was to improve that draft questionnaire using a further group of patients. In four iterative focus groups, 16 people with severe asthma completed the draft questionnaire, discussed the wording and structure and suggested changes that were incorporated into the final version. Results The original intention to ask patients to identify whether problems were caused by asthma symptoms or side effects of medication was abandoned as the attribution of cause was found to be difficult and inconsistent. The recall period of 2 weeks was acceptable but fails to reflect the patients’ desire to express the variability of severe asthma. Patients suggested improvements to the wording of the draft questionnaire, including splitting some items in two, combining two items in one, and changes to some of the words in individual items and the response scale. Conclusions The final version of the questionnaire was substantially different from one constructed using only qualitative reports from patients about the quality of life deficits of severe asthma. Patients make a valuable contribution to the questionnaire if they are asked to comment and improve an initial draft and where patients are treated as partners in the process of questionnaire construction, rather than only as a source of information to experts who construct the questionnaire
