13 research outputs found

    sj-docx-3-tag-10.1177_17562848221101722 – Supplemental material for SARS-CoV-2-inactivated vaccine hesitancy and the safety in inflammatory bowel disease patients: a single-center study

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    Supplemental material, sj-docx-3-tag-10.1177_17562848221101722 for SARS-CoV-2-inactivated vaccine hesitancy and the safety in inflammatory bowel disease patients: a single-center study by Yubin Cao, Jiaming Feng, Shihao Duan, Yi Yang and Yan Zhang in Therapeutic Advances in Gastroenterology</p

    sj-docx-2-tag-10.1177_17562848221101722 – Supplemental material for SARS-CoV-2-inactivated vaccine hesitancy and the safety in inflammatory bowel disease patients: a single-center study

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    Supplemental material, sj-docx-2-tag-10.1177_17562848221101722 for SARS-CoV-2-inactivated vaccine hesitancy and the safety in inflammatory bowel disease patients: a single-center study by Yubin Cao, Jiaming Feng, Shihao Duan, Yi Yang and Yan Zhang in Therapeutic Advances in Gastroenterology</p

    sj-docx-1-tag-10.1177_17562848221101722 – Supplemental material for SARS-CoV-2-inactivated vaccine hesitancy and the safety in inflammatory bowel disease patients: a single-center study

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    Supplemental material, sj-docx-1-tag-10.1177_17562848221101722 for SARS-CoV-2-inactivated vaccine hesitancy and the safety in inflammatory bowel disease patients: a single-center study by Yubin Cao, Jiaming Feng, Shihao Duan, Yi Yang and Yan Zhang in Therapeutic Advances in Gastroenterology</p

    Fertility, Education, and Market Failures

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    We show that coordination failures may be part of an explanation for the demographic differences between rich and poor countries and their differing attitudes towards the use of child labor. Our analysis is carried out within a two-period, general equilibrium model with endogenous fertility, parental investment in children's education and firms' tradeoff between traditional technologies and the adoption of skill-intensive, modern ones. The model exhibits multiple equilibria due to the lack of a coordination mechanism between parental decisions on the quantity and the quality of children and entrepreneurs' technology choices.Endogenous fertility, education, child labor, skill-biased technology, welfare, multiple equilibria, coordination

    Table_1_The application of metagenomic next-generation sequencing in pathogen diagnosis: a bibliometric analysis based on Web of Science.docx

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    BackgroundInfectious disease is a large burden on public health globally. Metagenomic next-generation sequencing (mNGS) has become popular as a new tool for pathogen diagnosis with numerous advantages compared to conventional methods. Recently, research on mNGS increases yearly. However, no bibliometric analysis has systematically presented the full spectrum of this research field. Therefore, we reviewed all the publications associated with this topic and performed this study to analyze the comprehensive status and future hotspots of mNGS for infectious disease diagnosis.MethodsThe literature was searched in the Web of Science Core Collection and screened without year or language restrictions, and the characteristics of the studies were also identified. The outcomes included publication years, study types, journals, countries, authorship, institutions, frontiers, and hotspots with trends. Statistical analysis and visualization were conducted using VOSviewer (version 1.6.16) and CiteSpace (version 6.1. R3).ResultsIn total, 325 studies were included in the analysis after screening. Studies were published between 2009 and 2022 with a significantly increasing number from 1 to 118. Most of the studies were original articles and case reports. Frontiers in Cellular and Infection Microbiology and Clinical Infectious Disease were the most commonly cited and co-cited journals. Institutions and researchers from China contributed the most to this field, followed by those from the USA. The hotspots and frontiers of these studies are pneumonia, tuberculosis, and central nervous system infections.ConclusionThis study determined that mNGS is a hot topic in the diagnosis of infectious diseases with development trends and provides insights into researchers, institutions, hotspots and frontiers in mNGS, which can offer references to related researchers and future research.</p

    Graphite Nanoflake-Modified Mo<sub>2</sub>C with Ameliorated Interfacial Interaction as an Electrocatalyst for Hydrogen Evolution Reaction

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    Molybdenum carbide (Mo2C) is anticipated to be a promising electrocatalyst for electrocatalytic hydrogen production due to its low cost, resourceful property, prominent stability, and Pt-like electrocatalytic activity. The rational design of Mo2C-based electrocatalysts is expected to improve hydrogen evolution reaction (HER) performance, especially by constructing ultrasmall Mo2C particles and appropriate interfaces. Herein, composites of molybdenum carbide (Mo2C) quantum dots anchored on graphite nanoflakes (Mo2C/G) were fabricated, which realized a stable overpotential of 136 mV at 10 mA cm–2 for the HER with a small Tafel slope of 76.81 mV dec–1 in alkaline media, and operated stably over 10 h and 2000 cycles. The superior HER performance can be attributed to the fact that graphite nanoflakes could act as a matrix to disperse Mo2C as quantum dots to expose more active sites and guarantee high electronic conductivity and, more importantly, provide ameliorated interfacial interaction between Mo2C and graphite nanoflakes with appropriate hydrogen binding energy and charge density distribution. To further explore which kind of interfacial interaction is more favorable to improve the HER performance, density functional theory calculations and corresponding contrast experiments were also performed, and it was interesting to prove that Mo2C quantum dots anchored to the basal planes of defective graphite nanoflakes exhibit better electrochemical performance than those anchored on the edges

    Additional file 1 of Diagnostic performance of metagenomic next-generation sequencing for the detection of pathogens in cerebrospinal fluid in pediatric patients with central nervous system infection: a systematic review and meta-analysis

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    Additional file 1: Supplementary file. The command used in Stata Software. Supplementary Figure 1. The certainty of evidence measure by GRADE score system. Supplementary Figure 2. Forest plot for the positive likelihood ratio (PLR) of mNGS for the diagnosis of pediatric CNSI. Supplementary Figure 3. Forest plot for the negative likelihood ratio (NLR) of mNGS for the diagnosis of pediatric CNSI. Supplementary Figure 4. Forest plot for the Diagnostic Odd’s Ratio (DOR) Supplementary Table 1. Leave-one-out analysis depicting the pooled sensitivity and specificity
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