3,201 research outputs found
Mesoscale folding: A physical realization of an abstract, 2D lattice model for molecular folding
No full textLarge-area patterning by vacuum-assisted micromolding
No full textCommunication: Rapid micropatterning of polymers on rigid and flexible substrates can be achieved by the method-vacuum-assisted micromolding in capillaries (MIMIC)-introduced here. The Figure shows an oblique-view SEM image of a single hexagonal cell of a pattern produced by vacuum-assisted MIMIC. The use of vacuum reduced the time taken to fill the pattern with UV-curable polyurethane from similar to 30 min to similar to 15 s
Mesoscopic, templated self-assembly at the fluid-fluid interface
No full textThis paper demonstrates templated self-assembly-based on capillary forces-of millimeter-scale poly-(dimethylsiloxane) plates suspended at the water-perfluorodecalin interface. The system described abstracts the concept of "templating" from molecular templating and uses it to design millimeter-scale aggregates that self-assemble in ordered structures. This work points the way to new strategies for organizing complex, millimeter-scale structures
Guide for the program Exact-NL
No full textA detailed description is given of a set of programs called EXACT-NL, which computes fetch- or duration limited wave growth with an explicit expression for the resonant four-wave interactions. This guide is meant as a user's manual. lt describes the principles and usage of each program of the EXACT-NL model. We used the EXACT-NL model for the computation of shallow water growth curves (Weber) and for the investigation of the directional response of waves to variations in the wind field (Van Vledder) . The modifications necessary for these specific purposes are also described
Next, Chinatown: community design for transforming Rotterdam Chinatown
No full textThis report examines the role of an urban designer in a multicultural society. When an urban society is overlapped with a spatial and diverse cultural layer, a cultural community is seen as the essential unit for outreaching and interacting with this complex environment. Community design is required for an urban designer to explore the intersection of spatial design and community development methodologies, top-down and bottom-up decision-making. In this report, the author takes use of the case of Rotterdam Chinatown to develop an experimental community design methodology and apply it to the on-site practice. It aims to stimulate communication and resource links within the Chinese community in a globalization context by utilizing open spaces as a medium.This research starts with the preliminary background study, followed by creating a set of customized pattern languages as the communication, learning, and design tools to engage the Rotterdam Chinatown community and the Chinese community in Rotterdam. A live event held in public spaces of Rotterdam Chinatown is embodied as a performance to evaluate the efficiency of the vision co-created by stakeholders. The final outcome learns about the requirements of the Chinese community of Rotterdam and concludes with refined pattern language and scenario design based on the conditions of Rotterdam Chinatown. This participatory design methodology featured for the Rotterdam Chinatown community fosters a sense of ownership and empowerment among the community members and encourages active participation in shaping the future of the community in a pure bottom-up approach. Keywords: community design, cultural glocalization, Chinatown, pattern language, public spacehttps://www.goethe.de/ins/nl/nl/ver.cfm?event_id=24703855 this project is collected as one project of Goethe Investigation https://www.instagram.com/chinatown.r.comm/ this Instagram account recorded how this project was developingArchitecture, Urbanism and Building Sciences | Urbanis
Generation of solution and surface gradients using microfluidic systems
No full textThis paper describes a simple, versatile method of generating gradients in composition in solution or on surfaces using microfluidic systems. This method is based on controlled diffusive mixing of species in solutions that are flowing laminarly, at low Reynolds number, inside a network of microchannels. We demonstrate the use of this procedure to generate (1) gradients in the compositions of solutions, measured directly by colorimetric assays and (2) gradients in topography of the surfaces produced by generating concentration gradients of etching reagents, and then using these gradients to etch profiles into the substrate. The lateral dimensions of the gradients examined here, which went from 350 to 900 mum, are determined by the width of the microchannels. Gradients of different size, resolution, arid shape have been generated using this method. The shape of the gradients can be changed continuously (dynamic gradients) by varying the relative flow velocities of the input streams of fluids. The method is experimentally simple and highly adaptable, and requires no special equipment except for an elastomeric relief structure that can be readily prepared by rapid prototyping. This technique provides a new platform with which to study phenomena that depend on gradients in concentration, especially dynamic phenomena in cell biology (chemotaxis and haptotaxis) and surface chemistry (nucleation and growth of crystals, etching, and Marangoni effects)
Patterned deposition of cells and proteins onto surfaces by using three-dimensional microfluidic systems
No full textThree-dimensional microfluidic systems were fabricated and used to pattern proteins and mammalian cells on a planar substrate. The three-dimensional topology of the microfluidic network in the stamp makes this technique a versatile one with which to pattern multiple types of proteins and cells in complex, discontinuous structures on a surface. The channel structure, formed by the stamp when it is in contact with the surface of the substrate, limits migration and growth of cells in the channels. With the channel structure in contact with the surface, the cells stop dividing once they form a confluent layer. Removal of the stamp permits the cells to spread and divide
EPOS-NL is the Dutch solid earth science infrastructure for research on georesources and geohazards
No full textThe European Plate Observing System - Netherlands (EPOS-NL) is the Dutch research infrastructure for solid Earth sciences. EPOS-NL is a cluster of large-scale geophysical facilities for research on georesources and geohazards. It is a partnership between Delft University of Technology (TU Delft), the Royal Netherlands Meteorological Institute (KNMI) and Utrecht University (UU) and is funded by NWO, as part of the national roadmap for large-scale research infrastructure. EPOS-NL facilities include 1) The Earth Simulation Lab at UU, 2) The Groningen gas field seismological network and the ORFEUS Data Centre at KNMI, 3) The deep geothermal (DAP-)well to be installed on the TU Delft campus, and 4) A distributed facility for multi-scale imaging and tomography (MINT) at UU and TU Delft. EPOS-NL aims to further develop the infrastructure for solid Earth scientific research. It also makes cutting-edge research facilities and data available to (inter)national researchers, aiming to address key geo-societal challenges, notably: • Exploration for (renewable) geo-energy resources • Storage of fuels, CO2 and wastewater in the sub-surface, and • Hazards such as induced or natural earthquakes Addressing these challenges requires a multi-physics, multi-scale approach, and open access to state-of-the-art research facilities and data. EPOS-NL contributes to addressing these needs.Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Applied Geophysics and PetrophysicsGeo-engineeringReservoir EngineeringImPhys/Medical Imagin
Accelerating Building Energy Retrofitting with BIM-Enabled BREEAM-NL Assessment
No full textThe Paris Agreement requires building retrofitting practices to be more efficient and effective. However, the current practice for building energy retrofitting is lacking behind, and one reason for that is the time-consuming process of energy credit evaluation. Energy performance assessment such as BREEAM-NL in the Netherlands could apply a more automatic approach with the help of building information modelling (BIM) for an efficient building energy retrofitting evaluation process. However, to what extent BIM can help in accelerating energy performance evaluation in the BREEAM-NL certification process is under-examined. This paper first combines literature findings with practical interviews from a case study organization to present a holistic overview of the potential for automating energy-related credits evaluation in BREEAM-NL using BIM. To understand the possible impacts of such transition, a responsible, accountable, consulted, and informed (RACI) matrix is developed to map the impacts on different actors involved. Furthermore, to help practitioners in an organizational context to adopt a BIM-enabled energy credits assessment workflow, the case study organization is studied to (1) understand their current BIM use status; (2) propose a suitable starting point to take toward a BIM-enabled energy performance assessment for building energy retrofitting. Finally, the proposed starting point is demonstrated using a customized application, and the project team’s feedback is used to verify its efficiency and future directions are identified.Design & Construction ManagementIntegral Design & Managemen
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