341 research outputs found
Family Assessment- Author Index
Author Index (12 pages)
A-Z
A
Abbott, D.: 263 Abery, B.: 242 Abidin, R: 81, 265 Abramovitch, R: 134, 135, 136, 137, 139,142,143,144,145,146 Abril, s.: 118 Achenbach, T. M.: 12,47, 118, 223, 265 Acock, A. c.: 206 Adams, G. R: 205 Adams, S. J.: 226 Al-Khayyal, M.: 74 Alexander, J. F.: 75 Allisson, P. D.: 185 Alwin, D. F.: 182,191,194 Amato, P. R: 205- 231, 206, 207, 210, 213,215,216, 219, 221, 222, 224, 227,230 Ammerman, R : 263 Amoloza, T. 0 .: 170, 171,172,176, 179, 187, 188 Anastasi, A.: 265 Anderson, B. J.: 85 Anderson, c.: 117 Anderson, P. P.: 104 Anderson, S. A.: 79, 168, 177 Anthony, J.: 117 Apley, J.: 84 Aponte, H. J.: 117 Appelbaum, M.: 263 Arrington, A.: 11 Asher, S.: 82 Asterita, M. F. : 92 Attneave, c.: 121 Auslander, W. F: 85
Z
Zane, N .: 107, 119 Zetlin, A.: 263 Zill, N.: 83 Zuo, J.: 171, 180, 18
Family Assessment- Author Index
Author Index (12 pages)
A-Z
A
Abbott, D.: 263 Abery, B.: 242 Abidin, R: 81, 265 Abramovitch, R: 134, 135, 136, 137, 139,142,143,144,145,146 Abril, s.: 118 Achenbach, T. M.: 12,47, 118, 223, 265 Acock, A. c.: 206 Adams, G. R: 205 Adams, S. J.: 226 Al-Khayyal, M.: 74 Alexander, J. F.: 75 Allisson, P. D.: 185 Alwin, D. F.: 182,191,194 Amato, P. R: 205- 231, 206, 207, 210, 213,215,216, 219, 221, 222, 224, 227,230 Ammerman, R : 263 Amoloza, T. 0 .: 170, 171,172,176, 179, 187, 188 Anastasi, A.: 265 Anderson, B. J.: 85 Anderson, c.: 117 Anderson, P. P.: 104 Anderson, S. A.: 79, 168, 177 Anthony, J.: 117 Apley, J.: 84 Aponte, H. J.: 117 Appelbaum, M.: 263 Arrington, A.: 11 Asher, S.: 82 Asterita, M. F. : 92 Attneave, c.: 121 Auslander, W. F: 85
Z
Zane, N .: 107, 119 Zetlin, A.: 263 Zill, N.: 83 Zuo, J.: 171, 180, 18
Intentions And Information In Discourse
This paper is about the flow of inference between communicative intentions, discourse structure and the domain during discourse processing. We augment a theory of discourse interpretation with a theory of distinct mental attitudes and reasoning about them, in order to provide an account of how the attitudes interact with reasoning about discourse structure. INTRODUCTION The flow of inference between communicative intentions and domain information is often essential to discourse processing. It is well reflected in this discourse from Moore and Pollack (1992): (1)a. George Bush supports big business. b. He's sure to veto House Bill 1711. There are at least three different interpretations. Consider Context 1: in this context the interpreter I believes that the author A wants to convince him that (1b) is true. For example, the context is one in which I has already uttered Bush won't veto any more bills. I reasons that A's linguistic behavior was intentional, and therefore that A believ..
Creighton University School of Law Class of 1999
Graduates|Ackley, Thomas F.; Allen, Misty M.; Ambrose, Maureen A. (Vice President); Bennett, Oral R.; Bennington, Travis; Benson, Jason; Beuerlein, Rebecca; Birgeles, Joseph J.; Bogenrief, Jennifer J.; Bortolotti, Rebecca; Boylston, Charles P.; Boylston, Jennifer R.; Bradley, Sean; Burt, Bruce C.; Buzicky, Jody L.; Carroll, Thalia Downing; Caster, Kimberly K.; Caturano, Joseph M., Jr.; Caturano, Kristi M.; Chipps, Leanne M.; Christensen, Leslie Perkins; Chrystal-Clark, Jennifer; Clinger, Christian W.; Cole, Roy D.; Colemere, Jeffrey T.; Crowder, Thomas J.; Cuvelier, Shari F.; D'Angelo, Maryann J.; Dawson, Justin C.; Delfin, Elvie E.; Diamond David M.; Dickinson, Joshua C.; Dunn, Martha J.; Dworak, Don; Eckel, Gene; Faltin, Polly M.; Fehringer, Thomas M.; Fehringer, Thomas M.; Feistner, Dan; Flores, Oscar R.; Forehand, Mark Alan; Franek, Robert; Franzen, Marc; Frick, Robert J.; Furches, Christopher A.; Garza, Eli E.; Gill, Misty L.; Giroux, Daniel B.; Guerber, Shannon McGuire; Guilliatt, Scott M.; Guinan, Daniel J.; Gunem, Scott G.; Ham, Artemus W.; Hauptman, Kristin A.; Heronimus, Diana; Hess, Steven L.; Hilliard, Laura M.; Hiser, Mary Vizioli; Hoffman, Douglas; Holthe, Jonathan D.; Huff, Sterling T.; Hughes, Kimberley; Hult-Norris, Catherine E.; Jann, Douglas; Jemsek, Benjamin R.; Jones, Erin D.; Keating, Sean M.; Keim, Marcela A.; Kessler, Jay L.; Kotrapu, Dan; Kwong, Carmen; Larson, Jerry C.; Lau, Gary H. (Representative); Leighty, Shannon M.; Lennon, Noreen C.; Lentz, Carrie E.; Lisec, Angela M.; Lohr, John L., Jr.; Lorenz, Ryan J.; Lowe, Michael S.; Makens, Thomas J.; Mead, Michael O.; Meckna, Michael P.; Miller, J. Kevin; Miller, Johnathan B.; Mills, Dana Lavine; Miskulin, Teddi Ann (Representative); Mitilier, Jared J.; Moler-Lewis, Wendy; Morris, Mari Casi; Neumann, Pamela; Novak, Brian J.; O'Loughlin, April; Olson, Stephen J.; Oquist, Sarah L. (President); Osborne, Quinn M.; Ostrom, Kristin Anderson; Ottley, Samuel J., III; Paulson, David C.; Pecoraro, Marlo; Perez, David L.; Petersen, Erik S.; Post, Michael K.; Quedensley, Kimberly; Reefe, Patrick J.; Robbins, Charles McMahon; Roth, Benjamin J.; Roubal, Brett W.; Rowen, Thomas M.; Sall, David J.; Scheef, Joni R.; Sengstock, David M.; Sibert, Raynette; Steininger, Erika; Stockmann, Daniel; Stoller, Asher L.; Strickland, Darwin; Tanck-Adams, Jennifer; Teigen, Margaret E.; Ternent, Linda; Thibodeau, James R., Jr.; Thomas, Christopher D.; Tingey, David B.; Toon, Jason M.; Trefts, Steven; Troia, J. E.; Villebro, Jennifer; Watson, Evan C.; Weight, Rachelle; Weimer, Derek C.; Welsh, Joseph T.; Wilker, Kimberly; Will, Eric; Williamson, Dean E.; Wilson, Cynthia G.; Winterhof, Janis J.; Wiseman, Charles; Yocom, Jerry; Young, Michele; Zelda, Jeffrey M.; Brown, Mary (not pictured); Cleverly, Ivard (not pictured); Korte, Andrew (not pictured); Richardson, Jennifer A. (not pictured)|38 x 31 in. (landscape
Engineering microorganisms for the efficient synthesis of capsular polysaccharides and related enzymes
May 2020School of EngineeringHeparin and chondroitin sulfate (CS) are glycosaminoglycans (GAGs) with many biological and physiological functions that contribute to their widespread utilization as anticoagulants and anti-inflammatory drugs. These sulfated polysaccharides are primarily extracted and purified from animal tissues, where factors such as source material, manufacturing processes, and the presence of contaminants impact overall safety and biological and pharmacological efficacy. The past few years have seen an increased interest in the development of alternative GAG production methods, including chemical and chemo-enzymatic synthesis and biosynthesis from GAG-producing cells. As part of ongoing efforts to separate the food chain from the drug chain, we are engineering microbial metabolism in order to produce CS in Escherichia coli, and heparosan, a valuable precursor to heparin, in Bacillus megaterium.These efforts all fall under the umbrella of advances in the production, biosynthesis, and analysis of GAGs through engineering microorganisms.Chondroitinase ACII, a polysaccharide lyase isolated from Arthrobacter aurescens, has been widely used to aid the analysis and study of chondroitin and CS structure, but it is no longer commercially available. Two versions of recombinant chondroitinase ACII were prepared in E. coli and their activity, stability, specificity and action pattern were examined in order to fill this great need within the glycobiology research community. They were compared to a natively secreted A. aurescens enzyme, which displayed some subtle specificity differences towards uncommon CS substrates and can serve as a suitable replacement for the original, discontinued enzyme. Furthermore, the recombinant E. coli expressed versions of chondroitinase ACII developed and characterized herein, are suitable for general application in the structural determination of most standard chondroitin sulfatesFurthermore, although heparosan production in engineered Bacillus subtilis has been previously reported, the larger GRAS organism, Bacillus megaterium, is a more attractive alternative for industrial scale production since it possesses the intrinsic favorable properties of low protease activity and high secretion capability. We have engineered B. megaterium for heparosan production to exploit these attributes. The T7 RNA polymerase (T7 RNAP) expression system for B. megaterium, which allows tightly regulated and efficient induction of genes of interest, has been co-opted for control of heparosan synthase (PmHS2). Specifically, we show that B. megaterium MS941 cells co-transformed with pT7-RNAP and pPT7-PmHS2 plasmids can produce heparosan upon induction with xylose, providing an alternative, safe source of heparosan as a precursor for heparin production.Together with non-sulfated chondroitin produced by co-expression of E. coli strain K4 genes kfoA, kfoC, and kfoE in the non-pathogenic strain E. coli BL21, two important components of the biotransformation scheme are made available for in vitro CS production. This proof of principle represents an important checkpoint on the path toward de novo biosynthesis of chondroitin sulfate from simple carbon sources like glucose and glycerol in a single microbial host.The engineered production of non-sulfated chondroitin in moderate quantities (~1 g/L) in various microorganisms has been reported, but no industrial scale biotechnological process using E. coli to produce CS has been established to date. We are engineering E. coli for the production of CS through a biotransformation scheme, where the microbial non-sulfated chondroitin backbone, in either its normal or perdeuterated form, is sulfated in vitro using multiple E. coli strains to generate the required components. The utility of this system involves the expression of several active biosynthetic pathway enzymes and requires an examination of their specificity and stability. To this end, chondroitin 6-sulfotransferase, which catalyzes the transfer of sulfate to position-6 of N-acetylgalactosamine residues of chondroitin, was expressed by E. coli in active form. Additionally, activity improvements were made to another E. coli-expressed sulfotransferase, chondroitin-4-sulfotransferase, which catalyzes the transfer of sulfate to position-4 of N-acetylgalactosamine residues of chondroitin, through protein engineering strategies adopted to develop more stable mutants.Ph
The Effects of Bullying on Hannah Baker Reflected on Jay Asher’s Thirteen Reasons Why Novel (2007): A Sociological Perspective
This study focuses on the effect of bullying on Hannah Baker reflected on Jay Asher’s Thirteen Reason Why novel (2007). This study is a sociological perspective. This study aims to explain Hannah Baker’s bullying indicators, to depict the bullyingon Hannah Baker on Jay Asher’s Thirteen Reasons Why, to interpret the reasons of Jay Asher chooses bullying on Thirteen Reasons Why novel. There are two types of data, primary data and secondary data. There are three results of research from this novel. First, the indicators of bullying found in Thirteen Reasons Whythe novel by Jay Asher as follows gives an unpleasant look, body shaming, physical violence, ridicule, and touch a body part without permission. Second, the author describes the issue of bullying through character, events and setting. Third, the author addressed the bullying based on one of his relative's experience
Comparative transcriptomics and co-expression networks reveal tissue- and genotype-specific responses of QDTYS to reproductive-stage drought stress in rice (Oryza sativa l.)
Rice (Oryza sativa L.) is more sensitive to drought stress than other cereals. Particularly during reproductive stages, drought causes yield reductions of 50-80%. With at least 25 million hectares of drought-prone rainfed rice, drought remains a major environmental constraint to rice production. While a few gene-expression profiling studies in rice in response to drought at the reproductive stage have been conducted, our knowledge of biological mechanisms in this respect is limited. Analysis tends to be restricted relative to the drought susceptible Nipponbare-reference genome, potentially missing genes unique to tolerant donor genomes. The objectives of this Ph.D. research were i) understand the genome-wide transcriptional changes at the reproductive-stage using above-ground tissues, ii) identify drought-responsive modules and pathways and assess their potential role and contribution for reproductive-stage drought tolerance, and iii) evaluate the similarities and dissimilarities of drought quantitative trait loci, across three representative genomes and discuss the potential involvement of the identified candidate genes for drought tolerance. The research objectives were addressed through RNA-Sequencing the flag-leaf and panicle tissues using a Drought-Tolerant Yield introgression line, DTY-IL, and the recurrent parent Swarna, under moderate reproductive-stage drought stress. Also, RNA-Sequencing analysis was done using the Nipponbare-reference approach and analyzed using the representative genome from indica and aus subpopulation.
We employed RNA-Seq to independently analyzed transcriptomes of flag-leaf and panicle tissues of DTY-IL and Swarna under the well-watered condition and after two weeks of moderate reproductive-stage drought stress. Differential expression analysis showed a distinct gene expression profile between the two genotypes and tissues. In flag-leaf, Differentially Expressed Genes (DEGs) downregulated in Swarna under drought were related to post-translational modifications and photosynthesis. At the same time, upregulated DEGs in DTY-IL were enriched for antioxidant enzymes. In panicle, DEGs downregulated in Swarna under drought were involved in DNA damage repair pathways and photosynthesis. Simultaneously, DEGs upregulated in DTY-IL under drought were enriched for post-translational modification, especially ‘phosphorylation.’
A co-expression network approach across flag-leaf and panicle tissues in drought-stressed and control plants identified drought-responsive modules of putatively co-regulated genes within each network. In flag leaf, M14 showed distinct upregulation of cell-wall biogenesis and cytoskeleton-related genes in DTY-IL under drought. This lack of cell wall remodeling in Swarna was suggested to contribute to the leaf-rolling phenotype observed under drought. M16, on the other hand, was associated with the downregulation of photosynthesis-related genes in Swarna under drought. In the panicle, modules M10 and M15 showed upregulation of several secondary metabolic pathway genes in DTY-IL. M10 further showed significant upregulation of several receptor kinases in DTY-IL. Hub genes of importance in differential drought responses included an expansion in the flag leaf and two peroxidases in the panicle.
Overlaying differential expression data with allelic variation in DTY-IL quantitative trait loci allowed for the prioritization of candidate genes. They included a differentially regulated auxin-responsive protein, with DTY-IL-specific amino acid changes in conserved domains, as well as a protein kinase with a DTY-IL-specific frameshift in the C-terminal region. An additional candidate gene was identified in MH63 in the indica genome to be a potential negative regulator of drought. The approach highlights how the integration of differential expression and allelic variation can help discover mechanisms and putative causal contributions underlying quantitative trait loci for drought-tolerant yield.Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2023-05-01The student, Jeshurun Asher Tarun, accepted the attached license on 2021-04-07 at 15:38.The student, Jeshurun Asher Tarun, submitted this Dissertation for approval on 2021-04-07 at 15:38.This Dissertation was approved for publication on 2021-04-15 at 16:05.DSpace SAF Submission Ingestion Package generated from Vireo submission #16187 on 2021-09-16 at 17:01:54Made available in DSpace on 2021-09-17T02:34:15Z (GMT). No. of bitstreams: 3
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Lessons for Asian Countries from Pension Reforms in Chile
Chile's 1981 reform revolutionized pension design and created a system that was lauded and emulated widely. The main feature of the system was the creation of state-mandated, privately managed individual pension capitalization accounts based on contributions of employees. After nearly three decades of experience, there is a reassessment of the extent to which the pension system has achieved its objectives, particularly with respect to coverage and adequacy. In March 2006, the newly elected President Bachelet set up a Presidential Advisory Council on Pension Reform under the chairmanship of Mario Marcel to evaluate the existing pension system. This paper examines the rationale and the nature of the recommendations made by the Council. The analysis focuses on the structure of the proposed new pension system and risk-sharing implications of different pillars of the system, the accessibility of the existing pension system in terms of coverage, particularly for women and self-employed persons, the impact of reform on transaction costs; investment policies and management and their implications for rates of return and financial market development. The implications of the new system on pension design and policy debate in Asian countries are addressed. The paper suggests that must imbibe lessons from countries such as Chile and urgently undertake the task of constructing sustainable, robust and adequate pension systems and social safety nets.Chile, Asia, Pension Reform
Modelling and control of a variable-speed switched reluctance generator based wind turbine
This paper studies the system modelling and control aspects of switched reluctance generator (SRG) based variable speed wind turbines. A control system is implemented to provide proper operation of the SRG as well as power tracking capabilities for varying wind speeds. The control system for the grid side inverter that will allow the SRG to properly generate power to the system is also presented. Studies are presented of both the SRG and inverter control systems capabilities during a balanced three-phase fault. The paper will demonstrate that the SRG based wind turbine presents a feasible variable wind speed solution with good fault response capabilities
Most older pedestrians are unable to cross the road in time: a cross-sectional study
to compare walking speed in the UK older population with the speed required to utilise pedestrian crossings (≥1.2 m/s), and determine health and socio-demographic associations with walking impairment
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