14 research outputs found
Translating sex culture: Transnational sex education and the U.S.-Swedish relationship, 1910s–1960s
No full text“Translating Sex Culture: Transnational Sex Education and the U.S.-Swedish Relationship, 1910s–1960s” traces the history of American-Swedish sex education relations; the exchange, modification, and reception of sex instruction material; and the opponents of the subject who connected sex education to larger cultural issues. I demonstrate that from the 1910s–1960s, the establishment and growth of American sex education resulted from international collaboration, with special attention paid to Swedish sex education cultures and their integration into the American landscape. In the 1910s–1930s American sex education organizations and filmmakers crafted sex instruction films, pamphlets, and lectures and exported them across the globe. Swedish critics and physicians responded positively to American sex education cultures in Sweden. After World War II, however, American organizations imported Swedish ideas into the American landscape. Thus, Swedish sex education culture influenced American sex education and sexuality culture, shaping how countless citizens thought about sex in the post-World War II era. Conservative activists in the 1950s–1960s turned their ire about school sex education towards Sweden, contending that the American sex education culture had become too much like the Swedish system. This controversy stemmed from larger Cold War geopolitics and provoked a conservative cultural backlash against sex education. More broadly, this dissertation demonstrates that historians can no longer tell the history of sex education without examining the transnational relationship, as American sex education has never been divorced from outside perspectives.Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2023-05-01The student, Saniya Ghanoui, accepted the attached license on 2021-04-15 at 16:54.The student, Saniya Ghanoui, submitted this Dissertation for approval on 2021-04-15 at 17:16.This Dissertation was approved for publication on 2021-04-16 at 13:35.DSpace SAF Submission Ingestion Package generated from Vireo submission #16359 on 2021-09-16 at 20:10:06Made available in DSpace on 2021-09-17T04:04:27Z (GMT). No. of bitstreams: 3
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Previous issue date: 2021-04-16Embargo set by: Seth Robbins for item 118664
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Reason: Author requested closed access (OA after 2yrs) in Vireo ETD systemEmbargo set by: Seth Robbins for item 118664
Lift date: 2023-09-17T04:07:01Z
Reason: Author requested closed access (OA after 2yrs) in Vireo ETD systemAuthor requested closed access (OA after 2yrs) in Vireo ETD systemLimite
Novel 3D printed capsule to work as an auxiliary for enteric-coating for gastroprotective drug delivery system.
No full textIn the current research work, 3d printed capsules were printed by using FDM based 3D printer. A model drug punched into matrix tablets was put inside and encapsulated in the capsule. It was compared with the highly advanced ready-to-fill enteric-coated capsule Eudracap™ capsule. Solid Works and slicing software were used to design and cast off the shape of the capsule shell. The design of the cap and body was made and capsules were printed accordingly. All were evaluated for acid uptake and disintegration tests. In an acidic medium at pH 1.2, it has not been disintegrated or opened. While in the intestinal pH at 6.8 body and cap got separated after 45 ± 05 min. All sizes of capsules were also assessed for dosage form they can uphold. This could be a good option for customized drug delivery for human and animal studies
The transgenerational effects of Di(2-ethylhexyl) phthalate on female reproduction in mice
Get PDFDi(2-ethylhexyl) phthalate (DEHP) is a plasticizer used to confer flexibility and stability in common polyvinyl chloride products. DEHP can be found in numerous consumer products and is a ubiquitous chemical. Humans are exposed to DEHP daily due to its widespread use and ability to leach from out of products. DEHP and its bioactive metabolites are found in human tissues such as amniotic fluid, cord blood, breast milk, and human follicular fluid. Exposure to DEHP is a public health concern because DEHP is a known endocrine disrupting chemical and reproductive toxicant in females. The presence of DEHP in tissues vital for reproduction and development suggests that DEHP exposure occurs at various developmental stages; thus, posing as a potential toxicant for several generations.
Multiple organs are required to facilitate healthy reproduction. Organs within the hypothalamic-pituitary-ovary axis consist of the hypothalamus, anterior pituitary, and the ovary and are vulnerable to toxicant exposure. Specifically, the ovary is a heterogeneous organ composed of follicles, oocytes, corpora lutea, and interstitial tissue. The primary roles of the ovary are to produce sex steroid hormones and maintain a steady stream of growing follicles. Normal sex steroid hormone production by the mature follicles is essential for the maintenance of normal menstrual/estrous cyclicity, reproductive tract tissues, and non-reproductive tissues such as bones, the heart, and the brain. In addition, the mature antral follicle is the only follicle type capable of ovulating and releasing an oocyte for potential fertilization. Therefore, female fertility is dependent on the maintenance of a constant stream of growing follicles and sex steroid hormone secretion throughout the reproductive lifespan.
The ability of endocrine disruptors to cause disease and infertility is a major concern, but even more troubling is that some of the effects of DEHP may be multigenerational or transgenerational in nature. To obtain a multigenerational or transgenerational effect, the phenotype or the effect must be passed from one generation to a subsequent generation. During prenatal exposure, the F0 generation is exposed to DEHP during pregnancy. The F1 generation is exposed as a developing fetus and the F2 generation is exposed as the developing germ cells inside the fetus. Both the F1 and F2 generations are directly exposed and effects observed in these generations are considered multigenerational effects. The subsequent generation, the F3 generation, is the first generation that is not directly exposed to DEHP and any effects observed are considered transgenerational effects. The transgenerational phenomena does not involve direct exposure and usually involves epigenetic changes induced in the germline.
Limited information is available on the effects of environmentally relevant DEHP exposure on female reproduction and even less information is available on the effects of DEHP on female reproduction across generations. Therefore, the goal of my doctoral dissertation work was to investigate the multigenerational and transgenerational toxicant effects of DEHP on female reproduction. Specifically, I investigated the effects of prenatal and ancestral DEHP on ovarian steroidogenesis and folliculogenesis and how DEHP exposure affects female reproductive outcomes in the F1 – F3 generation of mice. Additionally, I investigated how prenatal and ancestral DEHP exposure disrupts gene expression and DNA methylation in juvenile mouse ovaries across generations.
First, I tested the hypothesis that prenatal and ancestral exposure to environmentally relevant doses of DEHP decreases folliculogenesis and impairs steroidogenesis in the F1 – F3 generations. Folliculogenesis is the process in which follicles in the ovary develop and mature towards ovulation to release the oocyte for fertilization. Steroidogenesis involves the production of sex steroid hormones by the mature follicle type. I found that prenatal DEHP exposure decreased folliculogenesis and the percentage of atretic follicles in adult ovaries the F1 generation. DEHP exposure disrupted folliculogenesis in adult ovaries in the F2 generation. Ancestral DEHP exposure accelerated germ cell transition into primordial follicles in neonatal ovaries in the F3 generation. I also found that prenatal DEHP exposure increases serum 17β-estradiol levels in the F1 generation and altered serum progesterone levels in the F2 generation.
Next, I tested the hypothesis that prenatal and ancestral DEHP exposure to environmentally relevant doses impair reproductive outcomes in the F1 – F3 generations of female mice. Sex organs are particularly sensitive to endocrine disruptors and during a developmental window of exposure. I found that prenatal and ancestral DEHP exposure caused precocious puberty and disrupted normal estrous cyclicity in all three generations of mice. I also observed changes in birth outcomes such as increased litter size in the F2 generation and increased percentage of female pups per litter in the F3 generation. Additionally, I found that prenatal DEHP exposure decreased fertility in the F1 and F2 generations. Specifically, prenatal DEHP exposure decreased the mating index and pregnancy rate in the F1 generation and decreased the gestational index in the F2 generation.
Further, I tested the hypothesis that prenatal and ancestral exposure to environmentally relevant doses of DEHP differentially expressed genes in pathways critical for ovarian functions and increased DNA methylation in whole ovaries in the F1 – F3 generations. I found that prenatal and ancestral DEHP exposure disrupted gene expression in various pathways in the ovary. In the F1 generation, prenatal DEHP exposure increased the expression of Dnmt1 and increased the percentage of 5-mC in the whole ovary. In the F2 generation, DEHP exposure decreased the expression of Tets. In the F3 generation, ancestral DEHP exposure decreased the expression of Dnmts, Tets, and decreased the percentage of 5-mC in the whole ovary. Collectively, my doctoral dissertation work shows that prenatal and ancestral exposure to environmentally relevant doses of DEHP cause multigenerational and transgenerational impairment of ovarian health and function, female reproductive outcomes, ovarian gene expression, and ovarian DNA methylation levels.Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2021-05-01The student, Saniya Rattan, accepted the attached license on 2019-04-01 at 17:02.The student, Saniya Rattan, submitted this Dissertation for approval on 2019-04-01 at 17:05.This Dissertation was approved for publication on 2019-04-11 at 09:41.DSpace SAF Submission Ingestion Package generated from Vireo submission #13437 on 2019-08-22 at 15:05:05Made available in DSpace on 2019-08-23T20:29:29Z (GMT). No. of bitstreams: 2
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Previous issue date: 2019-04-11Embargo set by: Seth Robbins for item 112094
Lift date: 2021-08-23T20:29:33Z
Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD systemEmbargo set by: Seth Robbins for item 112094
Lift date: 2021-08-23T20:36:18Z
Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD systemU of I Only Restriction Lifted for Item 112094 on 2021-08-24T09:15:34Z
The future of workplace with focus on user demand and value delivery
Get PDFThe subject of the paper is the development of a Value Adding Workplace concept to provide guidance for the future of the workplace with focus on user needs and value delivery. As the current pandemic fundamentally questions the benefits of office workplace, the author is outlining the need to look beyond short-term responsive measures and to emphasize attention on to the long-term post-pandemic improvements. The thesis work is based on an extensive literature research in combination with the feedback and expertise of the industry professionals. The key findings of the research pointed out at the facts that, in order to provide organization with a coherent framework to develop their own optimized workplace environment a Value Adding Workplace Model is proposed. Based on the four value drivers(Creativity, Productivity, Cost efficiency and Quality of Life) work should beperformed at the workplace best fitted for the respective task. This inevitably leads to a hybrid workplace solution with the corporate office, coworking office and workingfrom-home bringing their respective advantages together. The main concept is to no longer assign employees to a fixed desk or even a building; but to provide flexibility and focus on the qualitative output rather than to means of its performance. AI and machine learning will be taking over many existing repetitive jobs but at the same time offering new opportunities. However, machine learning is predicted to be further expanded towards more complex knowledge workers field of expertise, meaning that increasingly less workplaces will be required for repetitive tasks in the future.The subject of the paper is the development of a Value Adding Workplace concept to provide guidance for the future of the workplace with focus on user needs and value delivery. As the current pandemic fundamentally questions the benefits of office workplace, the author is outlining the need to look beyond short-term responsive measures and to emphasize attention on to the long-term post-pandemic improvements. The thesis work is based on an extensive literature research in combination with the feedback and expertise of the industry professionals. The key findings of the research pointed out at the facts that, in order to provide organization with a coherent framework to develop their own optimized workplace environment a Value Adding Workplace Model is proposed. Based on the four value drivers(Creativity, Productivity, Cost efficiency and Quality of Life) work should beperformed at the workplace best fitted for the respective task. This inevitably leads to a hybrid workplace solution with the corporate office, coworking office and workingfrom-home bringing their respective advantages together. The main concept is to no longer assign employees to a fixed desk or even a building; but to provide flexibility and focus on the qualitative output rather than to means of its performance. AI and machine learning will be taking over many existing repetitive jobs but at the same time offering new opportunities. However, machine learning is predicted to be further expanded towards more complex knowledge workers field of expertise, meaning that increasingly less workplaces will be required for repetitive tasks in the future
ANALISIS STRATEGI SUPPLIER RELATIONSHIP MANAGEMENT UNTUK BAHAN PENOLONG COATING OIL NPK DAN KARUNG NPK SUBSIDI PADA PT PETROKIMIA GRESIK
No full textJika membutuhkan abstrak atau isi jurnal silahkan menghubungi author melalui e-mail [email protected] atau [email protected]
Dipublikasikan tanggal: 16 Juli 202
PENGARUH MOTIVASI KERJA TERHADAP KEPUASAN KERJA KARYAWAN (STUDI KASUS: PT. PAMELING AGRO NUSANTARA)
No full textJika membutuhkan abstrak atau isi jurnal silahkan menghubungi author melalui e-mail [email protected] atau [email protected] atau [email protected]
Dipublikasikan tanggal: 29 Juli 202
Perancangan Buku Dokumentasi Visual Kreasi Kemasan Produk Oleh-oleh Khas Jawa Timur
Get PDFKemasan saat ini memberikan pengaruh yang besar dalam peningkatan daya saing produk-produk lokal terutama pada produk yang dikonsumsi langsung seperti olahan pangan. Peningkatan desain kemasan produk pada merek lokal akan semakin mendukung aktivitas promosi dalam pengembangan produk hasil olahan negeri seperti oleh-oleh khas daerah. Jawa Timur menjadi salah satu provinsi dengan peningkatan kreatifitas kemasan yang baik. Ini ditunjukkan dengan adanya karya-karya kemasan oleh-oleh khas daerah oleh para desainer muda yang masuk dalam jajaran Asian Star Packaging Awards. Kemasan-kemasan yang telah mengalami peningkatan tersebut berpotensi dijadikan sebagai referensi kemasan produk oleh-oleh lainnya mengingat belum ada media yang secara spesifik mendokumentasikan ragam kreasi kemasan oleh-oleh daerah khususnya Provinsi Jawa Timur dan kemasan sebagai bahan materi dari segi desain belum banyak diadaptasi menjadi karya literatur.
Perancangan buku visual kreasi kemasan oleh-oleh Jawa Timur ini menggunakan metode depth-interview, analisis konten, dan studi literatur. Depth-interview dilakukan kepada penulis buku kemasan dan narasumber yang berkaitan langsung dengan desain kemasan oleh-oleh Jawa Timur seperti Kepala seksi desain UPTI Makanan, Minuman, dan Kemasan Jawa Timur, pelaku UMKM, dan desainer lokal untuk mengetahui beberapa pandangan terkait kemasan oleh-oleh khas di Jawa Timur. Metode analisis konten dilakukan pada sampel kemasan oleh-oleh yang diambil dari kota atau kabupaten di Jawa Timur dengan tujuan untuk dianalisa sesuai unit analisis yang ditentukan. Data yang didapatkan dikomparasikan dengan komparator untuk mendapatkan isi konten buku yang sesuai. Target utama perancangan buku ini adalah desainer kemasan, praktisi, maupun pelaku UMKM itu sendiri.
Luaran dari peracangan ini merupakan buku dokumentasi visual kumpulan kreasi kemasan oleh-oleh Jawa Timur yang informatif dan modern, serta sebagai media promosi untuk memperkenalkan oleh-oleh khas Jawa Timur yang ditujukan untuk dewasa muda usia 18-25 tahun, dengan isi konten mulai dari pembahasan tentang oleh-oleh khas, peran penting kemasan terhadap oleh-oleh, potensi desain kemasan oleh-oleh di Jawa Timur, dan pembahasan berbagai kreasi kemasan oleh-oleh khas Jawa timur yang didokumentasikan dengan teknik fotografi dan ilustrasi.
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Packaging gives a great effect in increasing local product’s competitiveness especially product that is consumed directly such as food. The enhancement of a product’s packaging design on a local brand will support promotion activity in enhancing domestic product like regional souvenirs. East Java becomes one of the provinces with good packaging creativity enhancement. It is shown by the souvenirs packaging creations made by young designers who are included in Asian Star Packaging Awards. The packaging that has been enhanced is potentially made as a reference by other souvenirs, considering there has not been any media that specifically documenting the variety of regional souvenirs packaging creation especially of East Java Province. Packaging as a resource material from a design’s perspective has not been much adapted into literary works.
Depth interviews were carried out to an author of a book about packaging, and resource persons who are directly related to the design of souvenir packaging in East Java such us the chief of package design in UPTI Makanan, Minuman, dan Kemasan Jawa Timur, UMKM, and local packaging designers to find out some views regarding souvenir packaging. The method of content analysis is carried out on samples of souvenir packages taken from cities or districts in East Java to be analyzed according to the specified unit analysis. Then, the obtained data was compared with comparison to get corresponding content. The main targets of this book are packaging designer, practitioner, and people who run UMKM.
The result of this design is an informative and modern visual documentation book of East Java souvenirs packaging creation. It is also used as a media to introduce souvenirs from East Java which is aimed at young adults of 18-25 year old. The content of the book includes the explanation of typical souvenirs, the importance of souvenirs packaging, packaging design potential of souvenirs in East Java, and the explanation of the variety souvenirs packaging creation of East Java which are documented by photography technique and illustration
Oppression and Alienation: A Study of Saniya Saleh’s Short Story Collection Al- Ġobār [The Dust]
No full textلم تحظ بعض النماذج القصصيّة بالاهتمام النقديّ عند صدورها، فاندثرت في زوايا النسيان دون أن تجد قارئًا يزيل عنها غبار الاهمال، أو ناقدًا يعيد اكتشافها عن طريق القراءة الهادفة المتفحّصة لما خلف السطور، تعدّ مجموعة سنية صالح القصصيّة من هذه الكتب التي لم تنل حقها من الدراسة.
يحاول البحث التعريف بالأديبة سنيّة صالح وأهم إبداعاتها، دلالة العنوان، تجربة سنيّة صالح في الكتابة القصصيّة. البناء القصصيّ للمجموعة، تقديم قراءة تحليليّة، مبرزة موضوعاتها ومضامينها.
يهدف البحث إلى الإجابة عن السؤال: ما الآليات التي اعتمدتها الكاتبة في توظيف ثيمتي الاغتراب والقهر في مجموعتها القصصيّة، من خلال تحليل عناصر البناء الفنيّ: المكان، الزمان، الأسلوب، وتوظيف اللغة، والكشف عن تجليات الفقر، الجوع، والألم في بنيّة الشخصيات والسرد.Not all short story collections receive enough critical attention when published, which can cause them to fade into obscurity due to a lack of readers or scholarly reevaluation. One such overlooked work is Saniyya Salih’s short story collection, al-Ġobār [The Dust], which has not been given the scholarly analysis it deserves. This study introduces the author Saniyya Salih and highlights her most important literary contributions, including the significance of the collection’s title and her experience writing short stories. The research examines the narrative structure of the collection and offers an interpretive reading that sheds light on its main themes and content. The main goal of this study is to answer the following question: What techniques did Salih use to portray the themes of alienation and oppression in her short story collection? This involves analyzing the aesthetic elements of the narrative—such as setting, time, style, and language—and showing how poverty, hunger, and suffering are portrayed through Salih’s characters and narrative framework
