2,382 research outputs found

    Oral history interview with William Doyle

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    William Doyle is the author of An American Insurrection

    Supplementary data for Coiro, Doyle and Hilton

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    Data and script used to generate the graph in Figure 4 in Coiro, Doyle and Hilton.data.csv : Pollen data in a tabular formattree.nex: tree for analysisScript.r: R scriptmagallon_tree aperture data.nex : nexus version of the data and tree including only angiosperms.</div

    Sir Arthur Conan Doyle

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    Sir Arthur Conan Doyle (right) was a doctor and an author

    Cupiennin 1a, an antimicrobial peptide from the venom of the neotropical wandering spider Cupiennius salei, also inhibits the formation of nitric oxide by neuronal nitric oxide synthase

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    The definitive version is available at www.blackwell-synergy.comCupiennin 1a (GFGALFKFLAKKVAKTVAKQAAKQGAKYVVNKQME-NH2) is a potent venom component of the spider Cupiennius salei. Cupiennin 1a shows multifaceted activity. In addition to known antimicrobial and cytolytic properties, cupiennin 1a inhibits the formation of nitric oxide by neuronal nitric oxide synthase at an IC50 concentration of 1.3 ± 0.3 µm. This is the first report of neuronal nitric oxide synthase inhibition by a component of a spider venom. The mechanism by which cupiennin 1a inhibits neuronal nitric oxide synthase involves complexation with the regulatory protein calcium calmodulin. This is demonstrated by chemical shift changes that occur in the heteronuclear single quantum coherence spectrum of 15N-labelled calcium calmodulin upon addition of cupiennin 1a. The NMR data indicate strong binding within a complex of 1 : 1 stoichiometry.Tara L. Pukala, Jason R. Doyle, Lyndon E. Llewellyn, Lucia Kuhn-Nentwig, Margit A. Apponyi, Frances Separovic and John H. Bowi

    Aftermath: Lost in a forest

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    Briohny Doyle (Victoria), author of Echolalia, reflects on the seductive myth of renewal in our personal and planetary lives.Griffith ReviewNo Full Tex

    A PSYCHOANALYSIS AND BIOGRAPHICAL ANALYSIS ON THE MAIN CHARACTER AS WELL AS THE AUTHOR OF SHERLOCK HOLMES : A STUDY IN SCARLET BY SIR ARTHUR CONAN DOYLE

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    A PSYCHOANALYSIS AND BIOGRAPHICAL ANALYSIS ON THE MAIN CHARACTER AS WELL AS THE AUTHOR OF SHERLOCK HOLMES : A STUDY IN SCARLET BY SIR ARTHUR CONAN DOYLE

    Reactivity and selectivity in intermolecular insertion reactions of chlorophenylcarbene

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    PT: J; CR: DOYLE MP, 1987, CHEM DIAZIRINES, CH8 DOYLE MP, 1987, J ORG CHEM, V52, P1619 GOULD IR, 1985, TETRAHEDRON, V41, P1587 GRAHAM WH, 1965, J AM CHEM SOC, V87, P4396 KIRMSE W, 1964, CARBENE CHEM MOSS RA, 1985, REACTIVE INTERMEDIAT, V3, CH3 MOSS RA, 1986, J AM CHEM SOC, V108, P7028 PADWA A, 1969, J ORG CHEM, V34, P2728 SEYFERTH D, 1967, J ORGANOMET CHEM, V7, P405 SEYFERTH D, 1968, J AM CHEM SOC, V90, P2944 SEYFERTH D, 1970, J ORG CHEM, V35, P1989 SEYFERTH D, 1973, J AM CHEM SOC, V75, P6763 SOUNDARARAJAN N, IN PRESS J AM CHEM S STANG PJ, 1987, J AM CHEM SOC, V109, P5019 STEINBECK K, 1978, TETRAHEDRON LETT, P1103 STEINBECK K, 1981, ANGEW CHEM INT EDIT, V20, P773; NR: 16; TC: 18; J9: TETRAHEDRON LETT; PG: 4; GA: R2217Source type: Electronic(1

    Constitutional Futures Podcast: Episode 15

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    In this episode, Prof Colin Harvey speaks with Oran Doyle.Oran Doyle is Professor in Law at Trinity College Dublin. He also holds a dual appointment as a research professor at the Academia Sinica in Taipei. Prof Doyle is an expert in comparative constitutional law, with a particular focus on the issues of constitutional amendment, territory and Irish unification. He is the author of 'The Irish Constitution: A Contextual Analysis' and (with Tom Hickey) 'Constitutional Law: Text, Cases and Materials'. Prof Doyle is a regular contributor to public debates on issues of constitutional law in Ireland

    Constitutional Futures Podcast: Episode 15

    No full text
    In this episode, Prof Colin Harvey speaks with Oran Doyle.Oran Doyle is Professor in Law at Trinity College Dublin. He also holds a dual appointment as a research professor at the Academia Sinica in Taipei. Prof Doyle is an expert in comparative constitutional law, with a particular focus on the issues of constitutional amendment, territory and Irish unification. He is the author of 'The Irish Constitution: A Contextual Analysis' and (with Tom Hickey) 'Constitutional Law: Text, Cases and Materials'. Prof Doyle is a regular contributor to public debates on issues of constitutional law in Ireland
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