454 research outputs found

    Shakespeare and child's play : performing lost boys on stage and screen

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    'Childness' - the essential nature of being a child - remains a vital critical issue for us today. In this text, Carol Rutter shows how recent performances on stage and film have used the range of Shakespeare's insights in order to re-examine and re-think these issues in terms of today's society and culture. Shakespeare wrote more than fifty parts for children, amounting to the first comprehensive portrait of childhood in the English theatre. Focusing mostly on boys, he put sons against fathers, servants against masters, innocence against experience, testing the notion of masculinity, manners, morals, and the limits of patriarchal power. He explored the nature of relationships and ideas about parenting in terms of nature and nurture, permissiveness and discipline, innocence and evil. He wrote about education, adolescent rebellion, delinquency, fostering, and child-killing, as well as the idea of the redemptive child who 'cures' diseased adult imaginations. 'Childness' - the essential nature of being a child - remains a vital critical issue for us today. In Shakespeare and Child's-Play Carol Rutter shows how recent performances on stage and film have used the range of Shakespeare's insights in order to re-examine and re-think these issues in terms of today's society and culture

    Análisis y preparación para la interpretación del Magnificat de John Rutter

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    El presente trabajo se centra en el Magníficat de John Rutter; compositor nacido en Londres (Inglaterra) el 24 de septiembre de 1945; y específicamente en su obra compuesta para orquesta, coro y voz femenina solista (soprano o mezzosoprano) en el año de 1990. En el cual, partiendo de una contextualización histórica y estética del compositor, y de un análisis musical de la misma, se busca profundizar en el conocimiento de esta obra contemporánea poco conocida e interpretada en Colombia y en Latinoamérica, y como consecuencia de ello, se busca visibilizar este tipo de repertorio sinfónico coral enmarcado dentro del repertorio sacro y brindar información que permita responder a las necesidades interpretativas y de preparación para el montaje de la obra. Como complemento, se adiciona un recorrido histórico del Magníficat como género musical religioso a lo largo de la historia y un análisis de los más importantes Magnificat para orquesta, coro y solistas, representantes de cada uno de los periodos de la música (barroco, clásico y romántico), los cuales serán comparados entre sí, incluyendo el Magnificat de John Rutter como obra analizada del período contemporáneo. Se encontrará en este trabajo cómo el Magnificat de Rutter, desde la mirada neotonalista del compositor, ofrece una obra ecléctica, con el empleo de técnicas modernas de composición que permite encontrar desde los elementos de la música contemporánea actual, el uso de polimétricas o métrica irregular, el empleo de ritmos exóticos, de elementos musicales propios del jazz, poliacordes o recursos del bitonalismo, diversas texturas corales y armonía modal. Desde los elementos propios a la tradición musical, incorpora acertadamente elementos del canto gregoriano, presenta tratamientos antifonales y con la incorporación de textos a la estructura del Magnificat, retoma el recurso utilizado en el siglo XV llamado, metáfora floral. Por lo anterior, este trabajo mostrará porqué el “Magnificat” de John Rutter posee elementos atractivos como obra contemporánea, de valor estético y belleza artística, que puede brindar a los músicos de hoy y a generaciones futuras, una experiencia musical interesante como reto artístico, y en el hoy, didácticamente refrescante para intérpretes y público en general. Es importante resaltar que este proceso que se describirá fue materializado gracias a que el autor de este trabajo, el 18 de noviembre de 2015, a las 7:00 PM, en el Teatro de Bogotá de la Universidad Central, presentó el montaje realizado durante 2015, del “Magnificat” de John Rutter, la cual se realizó con la Orquesta Sinfónica y el coro de la Universidad El Bosque, el Coro San Bartolomé y el Coro Institucional de la Universidad INCCA de Colombia. Soprano solista, la maestra Marissa Pérez.Abstract: This paper focuses on the Magnificat of John Rutter, composer born in London (England), on September 24, 1945, and specifically in his work, composed for orchestra, choir and voice female soloist (soprano or mezzo-soprano) in the year 1990. In which, it starting from a historical context and aesthetics of composer and musical analysis of it, seeks to deepen knowledge is little known and interpreted in our country and in Latin America contemporary work, and as a result it seeks to visualize this type of Orchestral and Choral Literature framed within the sacred repertoire, and provide information to answer the interpretative and preparation for assembly the work needs. As a complement, a historical approach of the Magnificat is added as a religious musical genre throughout history and an analysis of the most important Magnificat for orchestra, choir and soloists, representatives of each of the periods of music (baroque, classical and romantic), which will be compared with each other, including the Magnificat of John Rutter as work analyzed the contemporary period. You will find in this work as the Magnificat Rutter, from neotonalista look composer, it offers an eclectic work, with use of modern techniques of composition, to find from the elements of the current contemporary music, using polymetric or irregular rhythm, use of exotic rhythms, own musical elements of jazz, polychord or bitonalismo resources, various choral textures, modal harmony. And from the elements to the musical tradition, aptly it incorporates elements of Gregorian chant, has antiphonal treatments, and texts incorporating the structure of the Magnificat takes up the recuros used in XV century called floral matafora. Therefore, this paper will show why the "Magnificat" by John Rutter has attractive elements as contemporary work, aesthetic value and artistic beauty, which can give musicians of today and future generations, an interesting musical experience as an artistic challenge, and in today didactically refreshing for performers and public. It is important to highlight that this process to be described was materialized thanks to the author of this work on November 18, 2015, at 7:00 PM, at the Teatro de Bogota Central University, he presented the assembly carried out during 2015, the "Magnificat" by John Rutter, which was performed with the Symphony Orchestra and chorus of La Universidad El Bosque, San Bartolomé choir and the choir Institutional INCCA University of Colombia. Soprano Marissa Pérez.Maestrí

    Religion, cognition and author-function : Dyer, Southwell, Lodge and As You Like It.

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    The thesis incorporates the view that allegory as a mode of communication is impossible. Accordingly, religious meanings of Elizabethan literary texts usually read as "secular" works are registered herein without recourse to positing an allegorical level of meaning in those texts. In order to arrive at relatively secure readings, texts have been selected which have explicit interrelationships (for example, texts which are parodies or adaptations of earlier texts). Registering the tenor of the later texts' departures allows contemporary production of meaning from the earlier works to be traced. The aim, however, is not merely to show that Elizabethan "secular" texts are far more religious than tends to be supposed; the thesis seeks to demonstrate the extent to which theories of cognition were inseparable in the period from doctrinal issues. Early modems not only thought and read religiously, religious concepts informed their cognitive theories (and vice versa). The thesis culminates in a reading of As You Like It, arguing that the play employs facultative rhetoric (as derived from scholastic faculty psychology) in order to present human appetence as co-efficient in salvation. In doing so, the play downgrades the role of the intellectual faculty. The notion of author/dramatist as governing intellect is thereby brought into question. Accordingly, the thesis also traces the development of attitudes towards author-function in its study-texts, demonstrating the extent to which a given text's cognitive model and its rhetorical stance towards crucial doctrinal issues (relating to human participation in salvation) affect its deployment of, and attitude towards, author-function

    The LYR Factors SDHAF1 and SDHAF3 Mediate Maturation of the Iron-Sulfur Subunit of Succinate Dehydrogenase

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    SummaryDisorders arising from impaired assembly of succinate dehydrogenase (SDH) result in a myriad of pathologies, consistent with its unique role in linking the citric acid cycle and electron transport chain. In spite of this critical function, however, only a few factors are known to be required for SDH assembly and function. We show here that two factors, Sdh6 (SDHAF1) and Sdh7 (SDHAF3), mediate maturation of the FeS cluster SDH subunit (Sdh2/SDHB). Yeast and Drosophila lacking SDHAF3 are impaired in SDH activity with reduced levels of Sdh2. Drosophila lacking the Sdh7 ortholog SDHAF3 are hypersensitive to oxidative stress and exhibit muscular and neuronal dysfunction. Yeast studies revealed that Sdh6 and Sdh7 act together to promote Sdh2 maturation by binding to a Sdh1/Sdh2 intermediate, protecting it from the deleterious effects of oxidants. These studies in yeast and Drosophila raise the possibility that SDHAF3 mutations may be associated with idiopathic SDH-associated diseases

    What makes for stress or depression among select residents in rural western Wisconsin: namely Barron, Chippewa, Dunn, Pierce, Polk, and St. Croix county's population meeting the 1998 U. S. Department of Health and Services poverty guideline

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    Plan BEach of us encounters daily responsibilities and obligations, along with pressures that challenge are very existence called stress or depression. The purpose of this correlational study was to identify areas of need contributing to, or influencing stress or depression in the impoverished rural western Wisconsin residents. The randomly selected sample group for this study included 785 subjects age eighteen and older living in Barron, Chippewa, Dunn, Pierce, Pepin, Polk, and St. Croix counties. The subjects were selected from the West Central Wisconsin Community Action Agency’s, (West CAP), Client Intake System, (CIS), which included over 3,000 entries from these seven counties. Also, 310 subjects were selected from the Low Income, Housing, and Energy Assistance Program, (LIHEAP), listing in the seven counties. The results obtained by this author include all correlations among the 15 categories contained in this study, yielding a total of 225 inter-correlations. The author has presented an analysis of only those 15 variables, which are directly correlated with stress or depression. The discussion centered on the most critical needs identified which were the need for counseling, and food, and nutrition. The most significant of these need areas is counseling. The Pearson Product Moment Correlation Coefficient identified that all but one of the independent variables correlates with stress or depression. This author concludes that there is a need for additional and more specific research conducted with rural low-income populations. This study leaves question around how poverty level relates to the degree of self-reported stress or depression. Thus, the present study fills a need for information concerning degrees of stress and depression in rural populations

    Pancreatic and duodenal homeobox 1 (PDX1) phosphorylation at serine-269 is HIPK2-dependent and affects PDX1 subnuclear localization

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    Pancreatic and duodenal homeobox 1 (PDX1) regulates pancreatic development and mature beta-cell function. We demonstrate by mass spectrometry that serine residue at position 269 in the C-terminal domain of PDX1 is phosphorylated in beta-cells. Besides we show that the degree of phosphorylation, assessed with a phospho-Ser-269-specific antibody, is decreased by elevated glucose concentrations in both MIN6 beta-cells and primary mouse pancreatic islets. Homeodomain interacting protein kinase 2 (HIPK2) phosphorylates PDX1 in vitro; phosphate incorporation substantially decreases in PDX1 S269A mutant. Silencing of HIPK2 led to a 51+/-0.2% decrease in Ser-269 phosphorylation in MIN6 beta-cells. Mutation of Ser-269 to phosphomimetic residue glutamic acid (S269E) or de-phosphomimetic residue alanine (S269A) exerted no effect on PDX1 half-life. Instead, PDX1 S269E mutant displayed abnormal changes in subnuclear localization in response to high glucose. Our results suggest that HIPK2-mediated phosphorylation of PDX1 at Ser-269 might be a regulatory mechanism connecting signals generated by changes in extracellular glucose concentration to downstream effectors via changes in subnuclear localization of PDX1, thereby influencing islet cell differentiation and function

    Pressing Mitochondrial Genetics Forward

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    Mitochondria are crucial for many cellular functions. In this issue of Cell Reports, studies from Lanning et al. and Wolf and Mootha describe RNAi approaches to screening the mitochondrial proteome. Unexpectedly, they uncover key roles for two poorly characterized mitochondrial proteins: AK4 and FASTKD4. These studies provide examples of the power of forward genetic screens, even when screening a subset of genes, in deciphering functions of previously mysterious mitochondrial proteins

    LV21 Lightship - travelling collage installation - an evolving, collaborative and site responsive collage installation exploring ideas of narrative and context/history.

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    'Travelling Collage Installation' – an evolving, collaborative and site responsive collage installation exploring ideas of narrative and context/history. The objective is to create an evolving, changing artwork that responds to its location (and previous locations), that is temporary and is never resolved – a work that might last a lifetime. Contained within it, and hidden, is the narrative of its previous history. Ideas around narrative, 'back story' and incongruity, as well as the elements of chance and serendipity in its construction, are important to the project. The method thought most appropriate for this was the use of adapted and worked-over digital photographs and drawings which would be digitally printed at enlarged scale printed and collaged on to temporary constructions at a location. These drawn over and manipulated images were often made on mobile phones while travelling from the previous location, where the photographs were taken. This method also lends itself to the collaborative nature of the project (I work with my creative partner Chris Rutter). The work is portable and capable of being packed into a large suit case. Questions about how much information is required for a viewer to 'understand' a work and how much is, and should be, open to interpretation and 'projection' are implicit in the work. Ideas about the relationship between author(artist), audience and artwork, investigated by Umberto Ecco and Roland Barthes for example, are relevant here. The work so far has existed in a hotel room in Zurich (Limmathaus Hotel), a Duchamp Festival in Herne Bay, a decommissioned lightship on the River Medway (LV21), a gallery in Eindhoven (Kelderman en van Noort) and will be travelling to Cyprus in March 2018. The project has been supported by UCA Research Fund. link to LV21, Eindhoven, Duchamp Fest, Zurich
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