5,921 research outputs found

    Ebola epidemic over but flare-ups likely

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    The World Health Organisation says the world's worst Ebola epidemic to date is officially over. Dr Janet Scott is an Ebola expert from Liverpool University and spent a lot of time working in Sierra Leone during the epidemic. Is this really the good news the region's been waiting for

    Synthesis and structural characterization of two monomeric potassium phenolates

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    Copyright © 2005 Elsevier B.V. All rights reserved.Marcus L. Cole, Luke T. Higham, Peter C. Junk, Kathryn M. Proctor, Janet L. Scott and Christopher R. Strausshttp://www.elsevier.com/wps/find/journaldescription.cws_home/504086/description#descriptio

    La jolie fille de Perth / Walter Scott ; illustrée par Janet-Lange ; traduction de La Bédollière

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    Collection : Panthéon populaire illustré ; T. XV, N° 39Avec mode text

    Interview with Lawrence T. Scott on Fragments of fullerenes and carbon nanotubes: designed synthesis, unusual reactions, and coordination chemistry, edited by Marina A. Petrukhina and Lawrence T. Scott

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    As discussed in this interview, Fragments of Fullerenes and Carbon Nanotubes brings together international experts in the field to discuss their findings related to all aspects of this fascinating, beautiful and fairly recently discovered form of carbon. Familiarly known as "buckyballs" for their similarity in appearance to the highly symmetrical geodesic domes of Buckminster Fuller (and, also, soccer balls), fullerenes, and the related carbon nanotubes, hold out the tantalizing possibility of offering true superconductivity, with the potential to allow us to more efficiently harness our current electricity supply and to power the photovoltaic devices that could decrease our dependence upon oil and electricity. Professor Scott, widely recognized for his early and continued ground-breaking work in the "rational" synthesis of C60 (a spherical fullerene composed of 60 carbon atoms), serves as co-editor of this volume (and co-author of Chapter 9), along with his colleague, and long-time collaborator in the field, Professor Marina Petrukhina (University of Albany). With a foreword by Sir Harold Kroto, awarded the 1996 Nobel Prize in Chemistry (with Robert F. Curl and Richard E. Smalley, for their discovery of this class of compounds), this volume covers a wide range of topics including current methods of synthesis, molecular geometry, and reactivity with metals, as well as descriptions of newer members of the fullerene family of molecules and related compounds, including open geodesic polyarenes, called fullerene fragments or buckybowls.Title supplied by cataloger

    Dr. Scott Allison and Dr. Al Goethals – Faculty Author Interview

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    Dr. Scott Allison, Professor, Department of Psychology and Dr. Al Goethals, Professor, Jepson School of Leadership Studies discuss their recent book, Heroes: What They Do and Why We Need Them. Published by Oxford University Press, the book offers a stimulating tour of the psychology of heroism, shedding light on what heroism and villainy mean to most people and why heroes — both real people and fictional characters — are so vital to our lives. For more information on the book and project, connect to the “Heroes” blog

    Scott Urban

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    Photograph of Scott Urban. Scott Howard Urban (1961- ) is a poet, author, and educator in the Wilmington, NC area. He taught English at John T. Hoggard High School, and went to the University of North Carolina Wilmington to earn a Masters in School Administration. His works have been published in print magazines, horror anthologies, and online zines. He belonged to the Wilmington Writer's Forum and the Cape Fear Poetry Society, and currently lives out of state

    Measuring industry-science links through inventor-author relations: A profiling method

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    In this pilot study we examine the performance of text-based profiling in recovering a set of validated inventor-author links. In a first step we match patents and publications solely based on their similarity in content. Next, we compare inventor and author names on the highest ranked matches for the occurrence of name matches. Finally, we compare these candidate matches with the names listed in a validated set of inventor-author names. Our text-based profile methodology performs significantly better than a random matching of patents and publications, suggesting that text-based profiling is a valuable complementary tool to the name searches used in previous studies.innovation; industry-science links; text-based profiling;

    Kraichnan-Leith-Batchelor similarity theory and two-dimensional inverse cascades

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    We study the scaling properties and Kraichnan-Leith-Batchelor (KLB) theory of forced inverse cascades in generalized two-dimensional (2D) fluids (α\alpha-turbulence models) simulated at resolution 819228192^2. We consider α=1\alpha=1 (surface quasigeostrophic flow), α=2\alpha=2 (2D vorticity dynamics) and α=3\alpha=3. The forcing scale is well-resolved, a direct cascade is present and there is no large-scale dissipation. Coherent vortices spanning a range of sizes, most larger than the forcing scale, are present for both α=1\alpha=1 and α=2\alpha=2. The active scalar field for α=3\alpha=3 contains comparatively few and small vortices. The energy spectral slopes in the inverse cascade are steeper than the KLB prediction (7α)/3-(7-\alpha)/3 in all three systems. Since we stop the simulations well before the cascades have reached the domain scale, vortex formation and spectral steepening are not due to condensation effects; nor are they caused by large-scale dissipation, which is absent. One- and two-point pdfs, hyperflatness factors and structure functions indicate that the inverse cascades are intermittent and non-Gaussian over much of the inertial range for α=1\alpha=1 and α=2\alpha=2, while the α=3\alpha=3 inverse cascade is much closer to Gaussian and non-intermittent. For α=3\alpha=3 the steep spectrum is close to that associated with enstrophy equipartition. Continuous wavelet analysis shows approximate KLB scaling E(k)k2\mathcal{E}(k) \propto k^{-2} (α=1\alpha=1) and E(k)k5/3\mathcal{E}(k) \propto k^{-5/3} (α=2\alpha=2) in the interstitial regions between the coherent vortices. Our results demonstrate that coherent vortex formation (α=1\alpha=1 and α=2\alpha=2) and non-realizability (α=3\alpha=3) cause 2D inverse cascades to deviate from the KLB predictions, but that the flow between the vortices exhibits KLB scaling and non-intermittent statistics for α=1\alpha=1 and α=2\alpha=2. The results will appear in \cite{BurgessEA2015}, which has been accepted to the \emph{Journal of Fluid Mechanics}

    DNA fusion gene vaccination mobilizes effective anti-leukemic cytotoxic T lymphocytes from a tolerized repertoire

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    The majority of known human tumor-associated antigens derive from non-mutated self proteins. T cell tolerance, essential to prevent autoimmunity, must therefore be cautiously circumvented to generate cytotoxic T cell responses against these targets. Our strategy uses DNA fusion vaccines to activate high levels of peptide-specific CTL. Key foreign sequences from tetanus toxin activate tolerance-breaking CD4+ T cell help. Candidate MHC class Ibinding tumor peptide sequences are fused to the C terminus for optimal processing and presentation. To model performance against a leukemia-associated antigen in a tolerized setting, we constructed a fusion vaccine encoding an immunodominant CTL epitopederived from Friend murine leukemia virus gag protein (FMuLVgag) and vaccinated tolerant FMuLVgag-transgenic (gag-Tg) mice. Vaccination with the construct induced epitopespecificIFN-c-producing CD8+ T cells in normal and gag-Tg mice. The frequency and avidity of activated cells were reduced in gag-Tg mice, and no autoimmune injury resulted. However, these CD8+ T cells did exhibit gag-specific cytotoxicity in vitro and in vivo. Also, epitope-specific CTL killed FBL-3 leukemia cells expressing endogenous FMuLVgag antigen and protected against leukemia challenge in vivo. These results demonstrate a simple strategy to engage anti-microbial T cell help to activate epitope-specific polyclonal CD8+ T cell responses from a residual tolerized repertoire

    Pushing back the limits: the fantastic as transgression in contemporary women's fiction

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    Moving on from Jackson's belief in fantasy as the literature of subversion, this thesis argues that by filtering Todorov's concept of the fantastic through a contemporary theoretical understanding of transgression, the stasis which has resulted from the obsessive desire to pin down a single definition of literary fantasy can be transformed into a dynamic and interactive narrative process. This dynamism then provides a particularly useful strategy for the fictional exploration of the problematic positionality of women within patriarchal society. The Introduction sets out and contextualises this theoretical framework, the particular significance of transgression to socio-political marginalisation being illustrated by reference to the work of post-Bakhtinian theorists such as Stallybrass and White. The importance of the precarious threshold positionality offered by the adoption of fantastic hesitancy on the part of the woman writer is also introduced. The three main textual sections each focuses upon four novels by contemporary women writers, taking as their themes women and the domestic, women and nightmare and women who are "larger than life" respectively. In each case the intervention of the fantastic is seen to be inseparable from the problematic relationship between prohibition and transgression, a relationship largely set up and explored through a preoccupation with enclosure. Throughout there is a presiding concern with the importance of paradox and ambivalence as a radical literary and political strategy. To this end the concluding section sets this thesis within a feminist fantasy framework, arguing that the problematic dynamism of the fantastic offers far more transformative possibilities than the "closed-system" of the feminist utopia. The originality of this thesis resides in the fact that it adds two further dimensions to existing perspectives on the fantastic. By fully integrating the concept of transgression as a narrative positionality as well as a category of content, it aims to extricate fantasy criticism from the bounds of genre theory. In addition, by combining this with a variety of feminist theoretical perspectives and by taking as its focus contemporary women's fiction, this thesis provides something still not otherwise available: a full-length feminist reading of the application of the fantastic to contemporary women's fiction
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