476 research outputs found
Slovenia as a narrative space of a spy novel
Roman Davida Millerja Spoznaj svojega sovražnika je poleti 1983 izhajal v podlistku časnika Delo. Objavljenih je bilo 67 nadaljevanj, v knjižni obliki pa ni izšel. Žanrsko gre za vohunski roman, zaradi česar ga uvrščamo med trivialno literaturo. Pisatelj, po narodnosti Anglež, si je za dogajalni prostor romana izbral Slovenijo oziroma njena turistično najbolj obiskana kraja Bohinj in Bled, zato se je potrebno seznaniti z nekaterimi osnovnimi pojmi komparativistične vede, imenovane imagologija, ki preučuje podobe tujega v nekem literarnem delu. Skozi zgodbo namreč spremljamo raziskovanje umora angleškega veljaka, hkrati pa spoznavamo lepote Slovenije, njene prebivalce, izpuščen ni niti največji slovenski pesnik France Prešeren. Ker jebila Slovenija takrat še ena izmed držav skupne države Socialistične federativne republike Jugoslavije, se pripovedovalec nekoliko dotakne tudi politične ureditve države in njenega gospodarskega stanja. V romanu se pojavlja tudi kar nekaj znanih predvsem angleških osebnosti, med katerimi gre izpostaviti zelo popularno pisateljico vohunskih romanov Agatho Christie.David Miller\u27s novel Meet your enemy came out in the feuilleton of Delo newspaper in the summer of 1983. 67 sequels were published but the novel has never come out in book form. As for the genre, it is a spy novel which makes it classified as trivial literature. The author, Englishman by nationality, chose Slovenia, strictly speaking, its most visited tourist sites Bled and Bohinj, for the narrative space of the novel. Therefore, it is necessary to be familiarized with some basic concepts of comparatist discipline called imagology which studies images of foreign in a literary work. Through the story we follow a murder investigation of an English personage and at the same time discover the beauties of Slovenia and its inhabitantseven the greatest Slovenian poet France Prešeren is not omitted. Since Slovenia was one of the republics in the Socialist Federal Republic of Yugoslavia at that period, the narrator also slightly touches the political organization of the country and its economic situation. In the novel, there are also several famous, mostly English personalities among which Agatha Christie, very popular author of spy novels, should be highlighted
The role of natural plant Compounds in autophagy
Eden izmed ključnih, evolucijsko ohranjenih, preživetvenih procesov je avtofagija,
katero lahko induciramo tudi s pomočjo naravnih spojin rastlinskega izvora. Le-te
najpogosteje izvirajo iz rastlin in so del tradicionalne kitajske medicine. Najbolj
preučene so resveratrol, DMC, berberin in celastrol, ki delujejo na zelo različne
načine. Resveratrol inducira avtofagijo preko mTOR kompleksa ter razgradnje
klasičnega receptorja avtofagije p62, DMC deluje odvisno od Atg proteinov, celastrol
preko inhibicije signalne poti Akt/mTOR in povečanja izražanja avtofagosomov in
p62, berberin pa preko hranilnega senzorja SIRT1. Vsem štirim naravnim spojinam je
skupno, da učinkovito inducirajo avtofagijo tarčnih celic in ne poškodujejo sosednjih,
zdravih celic. Tako predstavljajo velik potencial v medicini za zdravljenje rakavih in
drugih obolenj, zato je bil naš namen pregled literature o vlogi naravnih spojin
rastlinskega izvora v avtofagiji ter pregled že izvedenih študij o potencialni uporabi le-teh pri kemoterapiji. Zaradi dvoličnosti avtofagije, ki je lahko zaviralec, a tudi
spodbujevalec raka, je zelo pomembno poznavanje stadija tumorja, makrookolja ter
ustrezne kombinacije med avtofagija-inducirajočo spojino in kemterapevtikom. Kot
najboljše naravne spojine so se izkazali resveratrol, celastrol in DMC, ki inducirajo
avtofagijo v rakavih celicah ter zmanjšajo citotoksičen učinek kemoterapevtika na
okoljske zdrave celice. Naravne spojine same po sebi sicer že inducirajo avtofagijo, a
je njihov učinek na omejitev rasti rakavih celic boljši takrat, ko so uporabljene v
kombinaciji z ustreznim kemoterapevtikom.One of the crucial evolutionarily preserved survival processes is autophagy, which can
also be induced with the help of natural compounds of plant origin. These most
commonly originate from plants and are part of Chinese traditional medicine. The
most studied compounds are resveratrol, DMC, berberine and ceastrol, which work in
very different ways. Resveratrol induces autophagy via the mTOR complex and
degradation of the classical p62 autophagy receptor, DMC works dependent of Atg
proteins, celastrol inhibits Akt/mTOR signaling pathway and increases expression of
autophagosomes and p62 proteins and berberin works via the SIRT1 nutrient sensor.
All four natural compounds have in common that they effectively induce target cell
autophagy and do not damage neighboring, healthy cells. Thus, they represent a great
potential in medicine for the treatment of cancer and other diseases, so our purpose
was to review the literature on natural compounds of plant origin and review already
conducted studies on their potential use in chemotherapy. Due to the hypocrisy of
autophagy that can be inhibits or promotes cancer, it is very important to know the
stage of the tumor, the microenvironment and the appropriate combination of cancer
inhibitors based on autophagy and chemotherapeutics. Resveratrol, celastrol and DMC
have been shown to be the best natural compounds, inducing autophagy in tumor cells
and preventing the cytotoxic effect of the chemotherapeutic on healthy cells. It is
known that natural compounds already induce autophagy themselves, but have a better
effect on limiting the growth of cancer cells when used in a combination with
appropriate chemotherapeutics
Coordination of social security systems of Slovenia and those of former Yugoslavian countries
Svoboda gibanja spada med temeljne človekove pravice. Te pravice je le izjemoma mogoče omejiti. Zaradi želje po boljšem življenju, ob razvoju globalizacije, se ljudje vse pogosteje selijo in zaposlujejo v tujini. Večja mobilnost družbe je vplivala tudi na razvoj prava socialne varnosti, ki je prav zaradi migracij moral v smer vse višje ravni mednarodnega sodelovanja. V ta namen države sklepajo mednarodne sporazume s področja socialne varnosti, ki omogočajo, da osebe, ki dopolnijo dobo v različnih državah, pridobijo pravice s področja socialne varnosti, v enaki meri in pod enakimi pogoji kot osebe, ki dobo dopolnijo le v eni državi in uživajo pridobljene pravice zunaj domače države. Same pravice še vedno urejajo zakonodaje posameznih držav. Znotraj Evropske unije to področje urejajo koordinacijske uredbe, ki povezujejo različne sisteme socialne varnosti držav članic, ne uvajajo pa novih pravic, saj je materialno pravo prepuščeno posameznim državam članicam.
Z namenom varovanja svojih državljanov ter zaradi ekonomskih interesov, države sklepajo tudi bilateralne sporazume z državami izven Evropske unije. Dvostranski ali bilateralni sporazumi, ki jih sklepa Slovenija morajo biti seveda skladni z evropskim pravnim redom. Od vseh sklenjenih bilateralnih sporazumov, so najpogosteje uporabljeni sporazumi sklenjeni z državami bivše Jugoslavije, na podlagi katerih so varovane pravice delavcev, ki so dopolnili zavarovalno dobo v državah pogodbenicah.
V magistrskem delu je obravnavano področje uporabe bilateralnih sporazumov v kombinaciji s slovenskim oziroma evropskim pravnim redom, saj so v realnosti pogoste tudi kombinacije dopolnjene zavarovalne dobe v več državah Evropske unije ter državah, s katerimi ima Republika Slovenija sklenjene mednarodne sporazume.Freedom of movement is considered a fundamental human right. These rights can only be restricted in exceptional cases. Due to the development of globalization and people’s desire for a better life, people have increasingly started to move and work abroad. Society’s greater mobility has also had an impact on the development of social security law which, due to the increasing number of migrations, needed to increase the level of international cooperation. To this end, Member States conclude international agreements in the field of social security which allow persons who complete the required years of service in different countries to acquire social security rights to the same extent and under the same conditions as persons who complete their years of service in a single country, and to enjoy vested rights outside of their home state. The rights themselves are still governed by individual countries’ legislations.
Within the European Union, the field of social security is regulated by the Coordination Regulations, linking the various social security systems of the Member States. However, these regulations are not permitted to introduce new rights, as substantive law is left to be determined by individual Member States. In order to protect their citizens and due to economic interests, countries also conclude bilateral agreements with countries outside the European Union. Bilateral agreements concluded by the Slovenia must, of course, be in line with the Union acquis. Of all the bilateral agreements concluded, which protect the rights of workers who completed periods of insurance in the Contracting States, the most frequently used are those concluded with the countries of the former Yugoslavia.
This master\u27s thesis deals with the scope of bilateral agreements in combination with the Slovenian and Union acquis, as in practice, combinations of completed insurance periods are also common in several European Union countries as well as countries with which Slovenia concluded international agreements
Analysis of lifestyle habits of male and female students at Gimnazija Vič and differences between gender
Namen diplomskega dela je bil ugotoviti značilnosti vedenjskega sloga dijakov in dijakinj Gimnazije Vič v Ljubljani. V raziskavi je sodelovalo 100 dijakov in dijakinj prvega ter tretjega letnika. Uporabili smo prirejen anketni vprašalnik »Z zdravjem povezan vedenjski slog« (CINDI, 2017). Vprašalnik je vseboval 44 spremenljivk, s katerimi smo ugotavljali nekatere dejavnike vedenjskega sloga, ki so povezane z zdravjempredvsem pa njihove prehranjevalne navade, pogostost njihove telesne aktivnosti, konzumiranje tobaka, uživanje alkohola, količino nočnega počitka, doživljanje stresa, uspešnosti in samopodobe. Pridobljene podatke smo obdelali s programom SPSS za Windows. Za izračun razlik med spoloma, smo uporabili dvovzorčni t-test, zvezne numerične spremenljivke smo predstavili z uporabo srednje vrednosti in standardnega odklona. Podatke smo prikazali v preglednicah. Ugotovili smo, da dijaki (M = 4,78) zaužijejo več obrokov na dan kot dijakinje (M = 3,56) ter da dijakinje
(M = 2,66M = 3,40) pojedo več zelenjave in sadja kot dijaki (M = 2,663,32). Ugotovili smo tudi, da so na splošno dijaki bolj telesno aktivni kot dijakinje (dijaki v povprečju 4- do 6-krat na teden, dijakinje 2- do 3-krat na teden). Pri konzumiranju tobaka nismo ugotovili bistvenih razlik med spoloma, skupno pa kadi 33,0 % dijakov in dijakinj. Naša raziskava je pokazala, da 42,0 % dijakov in 26,4 % dijakinj občasno uživa alkohol. Ugotovili smo, da ima 32,0 % dijakov in 37,0 % dijakinj ustrezno količino nočnega počitka. Raziskava je pokazala, da so dijakinje v povprečju manj zadovoljne s svojo postavo, imajo nižjo samopodobo in so posledično bolj pod stresom v primerjavi z dijaki. Ugotovitve raziskave so uporabne za širšo in ožjo strokovno javnost.The purpose of my degree was to research what kind of lifestyle habits have high school students at Gimnazija Vič in Ljubljana. Our research involved 100 students, from first and third year of high school. We used a questionnaire, in which we also included some questions from questionnaire »Z zdravjem povezan vedenjski slog« (CINDI, 2017). The questionnaire contained 44 questions, from which we try to explore some of the factors of lifestyle habits that are connect with healthwhat kind of nutrition, sport, smoking, alcohol, sleep habits, stress experiences students have, if they feel successful and what kind of self-image they have. All datas in our research were analysed with IBM SPSS Statistics. Differences between male and female students were calculated with Two Sample t-test, numeric variables we introduced with mean and standard deviation. Datas were intoduced in tables. The research has shown that male students ate more meals during the day, than female students (M=4,78M=3,56) and it also shown that female students ate more vegetables (M=2,44M=2,66) and fruits (M=3,32M=3,40) than male students. The research has shown that male students were more often involved in physical and sport activities than female students (male students – 4 to 6 times per week, female students 2 to 3 times per week). Smoking habits were similar among male and female students, in total smoked 33,0% male and female students. Our research has shown that 42,0% male students and 26,4% female students consumed alcohol occasionaly. Healthy sleep habits had 32,0% male students and 37,0% female students. Female students were less satisfied with their bodies, they also had negative self-image and they were more stressed out in comparsion to male students. Findings of our analysis are useful for professional public
Dopad Rusko-Ukrajinské války na formování a obsah vládní energetické politiky České republiky
CHARLES UNIVERSITY FACULTY OF SOCIAL SCIENCES Institute of Social Studies Department of Public and Social Policy Master's Thesis 2023 Ema Brunovská CHARLES UNIVERSITY FACULTY OF SOCIAL SCIENCES Institute of Social Sciences Department of Public and Social Policy The impact of the Russian-Ukrainian war on the formation of the energy policy in the European Union Master's thesis Author: Ema Brunovská Study programme: Public and Social Policy Supervisor: prof. PhDr. František Ochrana, DrSc. Year of the defence: 2023 Abstract The Russia-Ukraine conflict has caused substantial problems to the European Union's energy policy, disrupting the region's energy security and posing repercussions for the transition to a lowering the heavily carbon energy system. The purpose of this thesis is to assess the influence of the Russia-Ukraine war on EU energy policy and prospective changes as a result of the situation. The study investigates the development of energy policy inside the EU using retrograde analysis and a historical institutionalism approach. It examines the implications of Russian gas and oil supply constraints, the possible implications on energy affordability and security, and the necessity for alternative energy sources. The thesis gives insights into the evolving dynamics of EU energy security by analysing...CHARLES UNIVERSITY FACULTY OF SOCIAL SCIENCES Institute of Social Studies Department of Public and Social Policy Master's Thesis 2023 Ema Brunovská CHARLES UNIVERSITY FACULTY OF SOCIAL SCIENCES Institute of Social Sciences Department of Public and Social Policy The impact of the Russian-Ukrainian war on the formation of the energy policy in the European Union Master's thesis Author: Ema Brunovská Study programme: Public and Social Policy Supervisor: prof. PhDr. František Ochrana, DrSc. Year of the defence: 2023 Abstrakt Rusko-ukrajinský konflikt spôsobil značné problémy v kontexte energetickej politiky Európskej únie, narušil energetickú bezpečnosť regiónu a má vplyv na doterajšie vízie v oblasti energetiky. Cieľom tejto práce je predostrieť vplyv rusko-ukrajinskej vojny na energetickú politiku EÚ a perspektívne zmeny v dôsledku vzniknutej situácie. Práca skúma vývoj energetickej politiky v rámci EÚ s využitím retrográdnej analýzy a prístupu historického inštitucionalizmu. Skúma dôsledky obmedzenia dodávok ruského plynu a ropy, možné vplyvy na dostupnosť a bezpečnosť energie a potrebu alternatívnych zdrojov energie. Práca poskytuje pohľad na vyvíjajúcu sa dynamiku energetickej bezpečnosti EÚ analýzou dokumentov zo zasadnutí Energetickej rady od apríla 2021 do júna 2023 s využitím obsahovej analýzy...Katedra veřejné a sociální politikyDepartment of Public and Social PolicyFaculty of Social SciencesFakulta sociálních vě
Le travail du coton chez les Ema de Timor portugais
2. Brigitte Clamagirand (C.N.R.S., Paris) telah dua kali tinggal dalam watu jang lama di daerah penduduk Kemak, Timor Portugis, untuk mengadakan penjelidikan. Penulis memaparkan berbagai tahap pengerdjaan kapas, jang hanja dikerdjakan oleh kaum wanita; untuk tiap tahap jang penting, mulai dari membersihkan kapas dari bidji2-nja sampai memberi warna (proses ikai) dan waktu penenunan, penulis memberikan semua istilah tehniknja beserta photo dan skemanja.(2) Brigitte Clamagirand (CRNS, Paris) has made two field trips of long duration among the Ema (Kemak) of Portuguese Timor; she presents us with the diverse phases of working of cotton, which, there, is exclusively the work of women. For each of the principal phases, from the gining of the wad, to the tinting (ikat process), to the weaving (with a back strap loom), the author gives us the technical terms with photographs and schémas.Clamagirand Brigitte. Le travail du coton chez les Ema de Timor portugais. In: Archipel, volume 3, 1972. pp. 55-80
The impact of the Russian-Ukrainian war on the formation of the energy policy of the European Union.
CHARLES UNIVERSITY FACULTY OF SOCIAL SCIENCES Institute of Social Studies Department of Public and Social Policy Master's Thesis 2023 Ema Brunovská CHARLES UNIVERSITY FACULTY OF SOCIAL SCIENCES Institute of Social Sciences Department of Public and Social Policy The impact of the Russian-Ukrainian war on the formation of the energy policy in the European Union Master's thesis Author: Ema Brunovská Study programme: Public and Social Policy Supervisor: prof. PhDr. František Ochrana, DrSc. Year of the defence: 2023 Abstract The Russia-Ukraine conflict has caused substantial problems to the European Union's energy policy, disrupting the region's energy security and posing repercussions for the transition to a lowering the heavily carbon energy system. The purpose of this thesis is to assess the influence of the Russia-Ukraine war on EU energy policy and prospective changes as a result of the situation. The study investigates the development of energy policy inside the EU using retrograde analysis and a historical institutionalism approach. It examines the implications of Russian gas and oil supply constraints, the possible implications on energy affordability and security, and the necessity for alternative energy sources. The thesis gives insights into the evolving dynamics of EU energy security by analysing..
Modeling of animal groups based on individual goals
Title: Modeling of animal groups based on individual goals Author: Ema Wayan Danielová Department: Department of Macromolecular Physics Supervisor: doc. RNDr. Viktor Holubec, Ph.D. Abstract: Collective motion represents a fascinating example of self-organization in non-equilibrium systems. This work introduces and examines a modified Vicsek model of collective motion, enhanced with alignment-induced local attractive and repulsive interactions. Numerical simulations demonstrate that such a system spontaneously forms stable clusters with a characteristic size determined by the interaction radius. The results show that group cohesion can be achieved even without periodic boundary conditions and by using using finite-range interactions that are reasonable from a biological perspective. Keywords: collective motion, Vicsek model, active matter, numerical simulations, self-organization, cohesion, interaction radius, non-equilibrium systemsNázev práce: Modelování skupin zvířat na základě cílů jednotlivců Autor: Ema Wayan Danielová Katedra: Katedra makromolekulární fyziky Vedoucí bakalářské práce: doc. RNDr. Viktor Holubec, Ph.D. Abstrakt: Kolektivní pohyb představuje fascinující příklad samoorganizace v nerovnovážných systémech. V této práci je navržena a zkoumána modifikace Vicsekova modelu kolektivního pohybu doplněná o lokální přitažlivé a odpudivé interakce vyvolané optimalizací směru. Numerické simulace ukazují, že takový systém spontánně vytváří stabilní skupiny s charakteristickou velikostí určenou interakčním poloměrem. Získané výsledky demonstrují, že koheze skupiny může být dosažena i bez použití periodických okrajových podmínek a s z biologického hlediska rozmumnými konečně-dosahovými interakcemi. Klíčová slova: kolektivní pohyb, Vicsekův model, aktivní hmota, numerické simualce, samoorganizace, koheze, interakční poloměr, nerovnovážné systémyDepartment of Macromolecular PhysicsKatedra makromolekulární fyzikyFaculty of Mathematics and PhysicsMatematicko-fyzikální fakult
Fictional persuasion, transparency, and the aim of belief
In this chapter we argue that some beliefs present a problem for the truth-aim teleological account of belief, according to which it is constitutive of belief that it is aimed at truth. We draw on empirical literature which shows that subjects form beliefs about the real world when they read fictional narratives, even when those narratives are presented as fiction, and subjects are warned that the narratives may contain falsehoods. We consider Nishi Shah’s teleologist’s dilemma and a response to it from Asbjørn Steglich-Petersen which appeals to weak truth regulation as a feature common to all belief. We argue that beliefs from fiction indicate that there is not a basic level of truth regulation common to all beliefs, and thus the teleologist’s dilemma remains.
We consider two objections to our argument. First, that the attitudes gained through reading fiction are not beliefs, and thus teleologists are not required to account for them in their theory. We respond to this concern by defending a doxastic account of the attitudes gained from fiction. Second, that these beliefs are in fact appropriately truth-aimed, insofar as readers form beliefs upon what they take to be author testimony. We respond to this concern by suggesting that the conditions under which one can form justified beliefs upon testimony are not met in the cases we discuss.
Lastly, we gesture towards a teleological account grounded in biological function, which is not vulnerable to our argument. We conclude that beliefs from fiction present a problem for the truth-aim teleological account of belief
Fictional Persuasion, Transparency, and the Aim of Belief
In this paper we argue that some beliefs present a problem for the truth-aim teleological account of belief, according to which it is constitutive of belief that it is aimed at truth. We draw on empirical literature which shows that subjects form beliefs about the real world when they read fictional narratives, even when those narratives are presented as fiction, and subjects are warned that the narratives may contain falsehoods. We consider Nishi Shah’s ‘teleologist’s dilemma’ and a response to it from Steglich-Petersen which appeals to weak truth regulation as a feature common to all belief. We argue that beliefs from fiction indicate that there is not a basic level of truth regulation common to all beliefs, and thus the teleologist’s dilemma remains. We consider two objections to our argument. First, that the attitudes gained through reading fiction are not beliefs, and thus teleologists are not required to account for them in their theory. We respond to this concern by defending a doxastic account of the attitudes gained from fiction. Second, that these beliefs are in fact appropriately truth-aimed, insofar as readers form beliefs upon what they take to be author testimony. We respond to this concern by suggesting that the conditions under which one can form justified beliefs upon testimony are not met in the cases we discuss.Lastly, we gesture towards a teleological account grounded in biological function, which is not vulnerable to our argument. We conclude that beliefs from fiction present a problem for the truth-aim teleological account of belief.<br/
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