2,222 research outputs found
Alumni Highlight: Sandeep Chadha
Get PDFSandeep Chadha is a Partner at Milestone Capital Advisors (AUM $800 million) and has 14-plus years of experience in fund raising, investments, asset management and divestments. As a part of senior management at Milestone, he oversees the private REIT portfolio including investments and asset management. Sandeep is responsible for setting up a domestic private REIT focused on investments in commercial assets. His past assignments include managing 25 million square feet of commercial real estate for Unitech and asset management of assets for Everstone Capital and IL&FS Milestone Realty
An Asymptotic Framework for Fox's H-Fading Channel With Application to Diversity-Combining Receivers
No full textUnified statistics are valuable in the performance analysis of communication systems. In this context, Fox's H-function has been shown to be eminently suitable for diverse scenarios. Another pivotal requirement is to have a low computational complexity, which is often hard to achieve for generalized models. Given this motivation, in this article we have presented high-power, low-complexity solutions for the outage probability (OP) and the average symbol error probability (SEP). Additionally, diversity techniques are harnessed for mitigating the effect of fading, which are then analysed based on the results derived. The entire methodology is governed by the origin probability density function rather than approximating the performance metrics under high-power. All the presented mathematical expressions are compared and validated through computer simulations (Monte-Carlo) to verify the accuracy of the proposed framework
Glycemic management during Jain fasts
No full textThis review describes the various fasts observed by adherents of the Jain religion. It attempts to classify them according to their suitability for people with diabetes and suggests appropriate regime and dose modification for those observing these fasts. The review is an endeavor to encourage rational and evidence-based management in this field of diabetology
Proceedings of ASME Turbo Expo 2013: Power for Land, Sea and Air, Volume 1A: Combustion, Fuels and Emissions
No full textShahrokh Etemad (with Sandeep Alavandi and Benjamin Baird) is a contributing author, Fuel Flexible Rich Catalytic Lean Burn System for Low Btu Fuels
Learning materials on railway transport
No full textThe learning materials were developed for capacity building activities to strengthen subregional connectivity in East and North-East Asia through effective economic corridor management. ESCAP East and North-East Asia Office worked with Mr. Goran Andreev under the supervision of Mr. Sandeep Raj Jain, Economic Affairs Officer, Transport Connectivity and Logistics Section (TCLS), ESCAP Transport Division in developing the learning materials.</p
Higher Himalayan Crystalline (HHC) Belt: its shear sense indicators and their implications on its tectonic evolution
No full textMitigation of Motion Sickness Using Optimal Speed Profiling in Automated Vehicles
No full textIt is anticipated that for the automated driving industry to grow, public acceptance is required. The trust and acceptance of automated vehicles are primarily dependent on the travelling experience of people. In automated vehicles, passengers are expected to be engaged in non-driving tasks that are likely to decrease their predictability of the vehicle manoeuvre. This would greatly increase their sensitivity to motion sickness, which a large population already suffers in manual driving. Developing a control algorithm to reduce motion sickness in automated vehicles is an absolute necessity. In this research, first, a novel method is proposed to design a test road profile. Next, the study presents an optimal control strategy that implements a speed profiling method to minimise Motion Sickness Dose Value (MSDV), suitable for objective evaluation of motion sickness; on the test road. The resulting manoeuvre from the proposed control algorithm is an 'active mode driving.' A time minimisation manoeuvre defined as 'passive mode driving' is also simulated on the same test road to examine the efficiency of the proposed algorithm. For validation, a subjective assessment is carried out with 16 participants using a driving simulator in a comparative study between the two driving modes. Subjective responses are recorded with MIsery SCale (MISC) during the exposure and with a Motion Sickness Assessment Questionnaire (MSAQ) at the end of the experiment. It is found that active mode driving resulted in 38% MSDV reduction than passive mode driving. Further, the mean MISC rating in active mode was 62% lower than passive mode driving.Mechanical Engineerin
Acute Ethanol Administration Rapidly Increases Phosphorylation of Conventional Protein Kinase C in Specific Mammalian Brain Regions in Vivo
Get PDFBackground
Protein kinase C (PKC) is a family of isoenzymes that regulate a variety of functions in the central nervous system including neurotransmitter release, ion channel activity, and cell differentiation. Growing evidence suggests that specific isoforms of PKC influence a variety of behavioral, biochemical, and physiological effects of ethanol in mammals. The purpose of this study was to determine whether acute ethanol exposure alters phosphorylation of conventional PKC isoforms at a threonine 674 (p-cPKC) site in the hydrophobic domain of the kinase, which is required for its catalytic activity.
Methods
Male rats were administered a dose range of ethanol (0, 0.5, 1, or 2 g/kg, intragastric) and brain tissue was removed 10 minutes later for evaluation of changes in p-cPKC expression using immunohistochemistry and Western blot methods.
Results
Immunohistochemical data show that the highest dose of ethanol (2 g/kg) rapidly increases p-cPKC immunoreactivity specifically in the nucleus accumbens (core and shell), lateral septum, and hippocampus (CA3 and dentate gyrus). Western blot analysis further showed that ethanol (2 g/kg) increased p-cPKC expression in the P2 membrane fraction of tissue from the nucleus accumbens and hippocampus. Although p-cPKC was expressed in numerous other brain regions, including the caudate nucleus, amygdala, and cortex, no changes were observed in response to acute ethanol. Total PKC? immunoreactivity was surveyed throughout the brain and showed no change following acute ethanol injection
Imatinib-associated massive upper gastrointestinal hemorrhage and hepatic encephalopathy in a child with Philadelphia positive acute lymphoblastic leukemia: A case report and review of the literature
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