504 research outputs found
Buddhism and the emerging world civilization essays in honor of Nolan Pliny Jacobson
No full textThis captivating new book, a milestone in Buddhist and comparative studies, is a compilation of seventeen essays celebrating the work and thought of Nolan Pliny Jacobson. The essays in this volume are organized around Jacobson's activities, publications, and interests. Authored by an impressive selection of scholars, the essays are grouped into four sections - "Historical Context," "Central Issues," "Practical Implications," and "The Japan Emphasis." Hajime Nakamura, Charles Hartshorne, Kenneth K. Inada, Seizo Ohe, and thirteen other philosophers discuss freedom, creativity, and Buddhism's self-corrective nature, setting forth their reasons for sharing Jacobson's ideas and visions
Multivariate elliptically contoured stable distributions: theory and estimation
No full textPublished in:
Nolan, J.P. Comput Stat (2013) 28: 2067. doi:10.1007/s00180-013-0396-7Stable distributions with elliptical contours are a class of distributions that are useful for modeling heavy tailed multivariate data. This paper describes the theory of such distributions, presents formulas for calculating their densities, and methods for fitting the data and assessing the fit. Efficient numerical routines are implemented and evaluated in simulations. Applications to data sets of a financial portfolio with 30 assets and to a bivariate radar clutter data set are presented
Safety and security review for the process industries : application of HAZOP, PHA, what-if and SVA reviews /
No full textDrawing on decades of industry experience, well-known safety author and senior Loss Prevention specialist at Saudi Aramco Dennis Nolan has distilled the essential procedures and checklists into this practical guide. As well as guiding the reader through the selection and efficient and complete execution of the alphabet soup of Hazard Analysis and Safety Reviews (HAZOP, PHA, What-IF, SVA, LOPA, Bowtie ...), Nolan shares his personal experience and illustrates otherwise dry procedures with real-world examples. Written from the perspective of the author's extensive experience in loss prevention and safety engineering, this comprehensive manual is intended to provide guidance on all the qualitative hazard analyses conducted for industrial and commercial processes, specifically for Preliminary Hazard Analysis (PHA), What-If, and Hazard and Operability (HAZOP) review teams. It also demonstrates how the methodology and procedures used for these reviews can be adopted and applied to the Security Vulnerability Analysis (SVA) and Site Security Plan (SSP), requirements under the US Department of Homeland Security's Chemical Facility Anti-Terrorism Standard (CFATS) of 2007. The book's pragmatic approach describes the responsibilities, methods, and documentation required for the performance of such procedures and demonstrates how to conduct them in a timely, effective, objective, and consistent manner as may be prescribed by a company's Process Safety Management (PSM) policy and security requirements. As well as updates throughout to reflect changing practices, the third edition incorporates a new section on cost/benefit analysis and descriptions of new qualitative and quantitative safety reviews such as LOPA (Layer of Protection Analysis) and Bow-Tie (a graphical alternative to HAZOP) and a new chapter to address revalidation of studies/reports after 5 years. As well as providing invaluable personal insights from his career in the process industries, Dennis Nolan has also added a wealth of new real-world examples, bringing the form-filling to life. And for the first time, the forms and checklists are available for purchasers of the book to download - making this a complete safety review toolkit. Helps you to achieve compliance and avoid disasters: Dennis Nolan combines his extensive personal experience with relevant industry examples to provide the checklists and best-practice guidance needed to negotiate the labyrinth of Hazard Analysis and Safety Review procedures. Keeps your knowledge up-to-date: Coverage of the latest forms of Hazard Analysis and Safety Review, including LOPA and Bowtie Saves time ... and money: Demonstrates how each of the typically required reviews is related, so that information and conclusions used on one may be transferred or adapted for another. Also helps you avoid the fines associated with non-compliance, e.g. fines of up to 25k per day imposed by the Department of Homeland Security in the USA for non-compliance with the Chemical Facility Anti-Terrorism Standard (CFATS).Previous edition: 2008.Includes bibliographical references and index.Print version record.Elsevie
An analysis of the effects of various compounds on alcohol and high-fat-diet-induced steatosis in rats and mice:
No full textExcessive alcohol consumption is known to result in fatty liver, or steatosis. A high-fat, low-carbohydrate diet also results in fatty liver. Furthermore, fatty liver is known to precede cirrhosis in both animals and humans, and cirrhosis precedes primary hepatocellular carcinoma in humans. A series of studies was first undertaken to determine whether exercise and/or certain dietary manipulations could affect fatty liver. Long-Evans rats were given either a high-fat, low-carbohydrate or a high-carbohydrate, low-fat version of liquid diet with or without alcohol. Livers were analyzed for fat and measures of carbohydrate metabolism in liver and plasma were taken, as well as blood glucose alcohol concentrations. Next, added exercise (run wheel), caffeine, antioxidants such as Vitamin E, diphenyl-para-phenylene diamine (DPPD), and selenium were examined as were the dietary additives cranberry powder and soy protein. Finally, based on ambiguous results involving each agent separately, caffeine and DPPD were combined. Following the conclusion of rat studies, C57BL6 mice were given a modified version of the Leiber-deCarli liquid diet with alcohol. The calorie manipulation described above was repeated in mice to determine whether alcohol-induced fatty liver would be exacerbated in the presence of a high-fat diet. Subsequently, the dietary additives Vitamin E, DPPD and Trolox were added. Striatum was taken for HPLC, and livers were taken for liver fat analysis and malondialdehyde (MDA) assay (as a measure of oxidative stress) respectively. Finally, an experiment was undertaken to determine a time course for withdrawal seizures in mice.
In rats, differences in liver glycogen did not account for differences in liver fat. Exercise and caffeine both resulted in significant changes in weight gain, and while combined they appeared to reduce alcohol-induced fatty liver, the effect was not significant. Separately, no protective properties of either exercise or caffeine were observed. Vitamin E and selenium were found to exacerbate alcohol-induced fatty liver, while DPPD did not. Neither cranberry powder nor soy protein affected alcohol-induced fatty liver. DPPD combined with caffeine reduced alcohol-induced fatty liver significantly (p<0.05).
Adult mice were able to tolerate 4.5% ethanol in a high-fat liquid diet. The high-fat diet resulted in liver fat values significantly higher than high-carbohydrate when combined with alcohol. Vitamin E appeared to exacerbate fatty liver in mice, but differences were not significant. There were significant differences in oxidative stress; Vitamin E and Trolox reduced MDA significantly over diet plus alcohol alone. All animals experienced withdrawal seizures between 3 and 5 hours after removal of alcohol. There were significant differences in serotonin turnover (5HIAA/5HT) in animals fed a high-fat diet without alcohol vs. chow controls.Ph.D.Includes bibliographical references (p. 52-60)by Bonnie Nola
Industrial policy and development in late industrializing countries: a case study of the motor industry
No full textIn recent times, literature - favouring a neo-classical
perspective - on industrialization in developing nations
has been the subnect of increasing criticism. The opponents of the neo-classical approach argue that outward-looking free market policies do not offer the best prospects for self-sustaining growth. In a straight forward manner, Chapter 1 airs the views of economists of both perspectives. Subsequently, a framework for a general discussion is provided.
Outward-looking industrial policies m Ireland, have
led to the emergence of a vibrant foreign-owned manufacturing sector. As Chapter 2 points out, there is
considerable evidence that outward-looking industrialization
has thus far been unsuccessful in developing strong native companies capable of entering export markets. Chapter 3 suggests that this may be a common experience among late industrializing countries (LICs). In fact, the creation of a competitive indigenous manufacturing base may be contingent upon a departure from strict neo-classical guidelines.
Chapter 4 shows that the development of the motor industry
in LICs has usually taken place under the auspices
of large transnational corporations (TNCs) from developed
countries. Only with active state intervention have
domestic firms - with the assistance of foreign capital
and technology - shown an ability to compete on the
world market. As Chapter 5 indicates, assembly of
motor vehicles in Ireland was dominated by the subsidiaries
of foreign companies. This is also true of the Irish automotive components sector, which has evolved in recent years. The analysis of this sector, contained m Chapter 5, is based largely on unpublished material. It is clear that this industry suffers from many of the short-comings often associated with foreign dominated sectors of Irish manufacturing.
By way of a conclusion, Chapter 6 argues that a role
exists for more state intervention. However, it warns
that government intervention in the system is not without
risk. The task facing policy makers is to design a constructive role for the state. With respect to the Irish manufacturing industry, m the absence of more state intervention, the development of export markets will remain beyond the reach of most indigenous producers
First estimates of age, growth, and maturity of boarfish (Capros aper): a species newly exploited in the Northeast Atlantic
No full textThis is a pre-copy-editing, author-produced PDF of an article accepted for publication in ICES Journal of Marine Science following peer review. The definitive publisher-authenticated version “White, E., Minto, C., Nolan, C. P., King, E., Mullins, E., and Clarke, M. 2011. First estimates of age, growth, and maturity of boarfish (Capros aper): a species newly exploited in the Northeast Atlantic. – ICES Journal of Marine Science, 68: 61–66” is available online at: http://icesjms.oxfordjournals.org/content/68/1/61peer-reviewedBoarfish in the Northeast Atlantic have recently been exploited commercially for fishmeal. It is a sexually dimorphic species with an estimated maximum age of 26 years, late age at maturity (A50 = 5.25 years), relatively fast rate of growth (K = 0.186 year−1), and a small asymptotic length (L∞ = 128.9 mm)
Knowing the code
No full textPublished in:
Cytometry part A, Volume 85, Issue 1, January 2014, Pages 10–1
Bark type classification product from Fuller et al. (manuscript in preparation). Biogeography of eucalypt bark types in south-eastern Australia.
No full textBark type classifications of eucalypt species (within the genera Eucalyptus, Corymbia, and Angophora), created as part of the following publication. See Supporting Information Appendix S1 or contact the corresponding author for further information:
Fuller, KJ, RH Nolan, MJ Aspinwall, MG Tjoelker, K Calders and MM Boer. (manuscript in preparation). Biogeography of eucalypt bark types in south-eastern Australia.
This work was funded by the Bushfire Risk Management Research Hub and Western Sydney University. Computing resources were provided by the National Center for Atmospheric Research.</p
Map product from Fuller et al. (manuscript in preparation). Biogeography of eucalypt bark types in south-eastern Australia.
No full textPredictions of euclaypt (species in the genera Eucalyptus, Corymbia, and Angophora) bark type distributions across forests and woodlands in the state of New South Wales, created as part of the following publication. See Supporting Information Appendix S1 or contact the corresponding author for further information:
Fuller, KJ, RH Nolan, MJ Aspinwall, MG Tjoelker, K Calders and MM Boer. (manuscript in preparation). Biogeography of eucalypt bark types in south-eastern Australia.
This work was funded by the Bushfire Risk Management Research Hub and Western Sydney University. Computing resources were provided by the National Center for Atmospheric Research.</p
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