127 research outputs found

    sj-docx-1-spp-10.1177_19485506221137161 – Supplemental material for Parental Transmission and the Importance of the (Noncausal) Effects of Education on Political Engagement: Missing the Forest for the Trees

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    Supplemental material, sj-docx-1-spp-10.1177_19485506221137161 for Parental Transmission and the Importance of the (Noncausal) Effects of Education on Political Engagement: Missing the Forest for the Trees by Stig Hebbelstrup Rye Rasmussen, Aaron Weinschenk, Christopher T. Dawes, Jacob v. B. Hjelmborg and Robert Klemmensen in Social Psychological and Personality Science</p

    Stability and C*-algebras arising from Graphs

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    This report is made for the midway qualifying exam that is part of the Ph.D. program at Department of Mathematics and Computer Science, Odense University, Denmark. The author wish to thank Mikael Rørdam for many helpful discussions and Lisbeth Larsen for typing the manuscript. 2 Introductio

    Pure infiniteness, stability and C*-algebras of graphs and dynamical systems

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    Pure infiniteness (in sense of [11]) is considered for C -algebras arising from singly generated dynamical systems. In particular, Cuntz-Krieger algebras and their generalizations, i.e., graph-algebras and OA of an infinite matrix A, admit characterizations of pure infiniteness. As a consequence, these generalized Cuntz-Krieger algebras are traceless if and only if they are purely infinite. In case of graph-algebras of locally finite graphs, stability is characterized by the absence of non-zero unital quotients and bounded trace. Also, graph-theoretical analogues of pure infiniteness and stability are obtained. 1 Introduction Following J. Renault [16] a singly generated dynamical system (SGDS), denoted (X; T ), consists in our setting of a locally compact, second countable Hausdorff space X and a local homeomorphism T from an open subset dom(T ) of X onto an open subset ran(T ) of X . One can associate a locally compact etale Hausdorff groupoid, denoted G(X;T ), that is also amena..

    Geners indflydelse på det lange liv

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    At flere bliver meget gamle skyldes ændringer i omgivelserne - spiller generne nogen rolle for levealderen, og navnligt blandt ældre? Udgivelsesdato: Mart

    Geners indflydelse på det lange liv

    No full text
    At flere bliver meget gamle skyldes ændringer i omgivelserne - spiller generne nogen rolle for levealderen, og navnligt blandt ældre? Udgivelsesdato: Mart

    Heritability of Caffeine Metabolism: Environmental Effects Masking Genetic Effects on CYP1A2 Activity but Not on NAT2

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    Heritability of caffeine pharmacokinetics and cytochrome P450 1A2 (CYP1A2) activity is controversial. Here, we analyzed the pharmacokinetics of caffeine, an in vivo probe drug for CYP1A2 and arylamine N-acetyltransferase 2 (NAT2) activity, in monozygotic (MZ) and dizygotic (DZ) twins. In the entire group, common and unique environmental effects explained most variation in caffeine area under the curve (AUC). Apparently, smoking and hormonal contraceptives masked the genetic effects on CYP1A2 activity. However, when excluding smokers and users of hormonal contraceptives, 89% of caffeine AUC variation was due to genetic effects and, even in the entire group, 8% of caffeine AUC variation could be explained by a CYP1A1/1A2 promotor polymorphism (rs2470893). In contrast, nearly all of the variations (99%) of NAT2 activity were explained by genetic effects. This study illustrates two very different situations in pharmacogenetics from an almost exclusively genetic determination of NAT2 activity with no environmental modulation to only moderate genetic effects on CYP1A2 activity with strong environmental modulation
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