1,720,984 research outputs found
Understanding a role of folliculotropic viral infections in the pathogenesis of psoriasis
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Topical treatment of actinic keratosis with 3.0% diclofenac in 2.5% hyaluronan gel: review of the literature about the cumulative evidence of its efficacy and safety
No full textTopical 3% diclofenac in 2.5% hyaluronic acid (HA) gel is a nonsteroidal anti-inflammatory drug approved for the treatment of actinic keratosis (AK). It has been shown to be a safe and effective for treatment of AK on both skin and mucosal lip
Atypical exanthems associated with parvovirus B19 infection: similarities and differences between adults and children
No full textGianotti-Crosti syndrome as presenting sign of cytomegalovirus infection: A case report and a critical appraisal of its possible cytomegalovirus etiology
No full textGianotti-Crosti syndrome (GCS) is a self-limiting exanthem of acute onset with a characteristic acral distribution, usually occurring in children. It is characterized by symmetric pink to red-brown papular or papulovesicular lesions that are a few millimetres in diameter, distributed on the face, buttocks and limbs. It may be accompanied by low-grade fever, hepato-splenomegaly and lymphadenopathy. GCS is considered a unique cutaneous response to viral infection, mostly associated with hepatitis B virus and Epstein-Barr virus (EBV), but other viruses, bacterial infections and recent immunizations may be inciting factors. We report a case of a 3-year-old girl presenting generalized, pruritic, papulovesicular eruption on the face and extremities for one month. In our case, GCS was related to cytomegalovirus (CMV) primary infection and may be considered the presenting sign of the infection. (C) 2016 Elsevier B.V. All rights reserved
Pustolosi cutanea e malattia di Crohn; Lupus subacuto indotto da minociclina; Una voluminosa massa del piede in una donna di 100 anni.
No full textPazopanib induced hand-food syndrome in a patient previously treated wiyh sunitinib:a possible cumulative skin toxicity ?
No full textHand-foot syndrome (HFS), also known as palmar-plantar erythrodysesthesia, is a skin toxicity that could be observed during target therapies such as with tyrosine-kinase inhibitors (TKI). It usually develops within the first 2 - 4 weeks of drug administration. We present a case of HFS induced by Pazopanib after 2 months of treatment, in patients previously treated with Sunitinib, suggesting a possible cumulative toxicity of two drugs. The clinical and therapeutic management of skin adverse reactions during TKI therapy usually requires 25% dose reduction and adequate local treatment. It is important for the clinicians to recognize clinical signs and symptoms of such skin toxicities. Attention should be paid especially when two or more drugs from the same class are used in combined treatment
Lightning discharges and discharges from overhead power lines with human burn injuries as consequences
No full textAbstract: Discharges from overhead power lines and lightning discharges may severely endanger human life and health. If non-lethal, burn injuries may also last for a lifetime, so as Lichtenberg figures caused by lightning discharges. Some accidents with burns are discussed in this paper and recommendations given for safety reasons. Specific energy transferred by typical lightning strokes currents given in the standard IEC 62305 is calculated. The aim of the paper is to suggest a simple expression for the estimation of safe approach distances to overhead lines, especially if high temperatures and changes in terrain reduced the secure height above ground, or if carrying elevated objects. Results of these calculations are compared to safe approach distances given in regulations of different countries. Safe distances from railway power lines are also considered
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