239 research outputs found

    An integrated approach to studying the positional candidate gene 1-deoxyxylulose-5-phosphate synthase (VvDXS) involved in Muscat flavor determination

    No full text
    Corresponding author: [email protected] audienceFragrance in table grapes and a persistent and complex aroma in wine are both sought after by the modern consumer. In particular, the floral flavor typical of Muscat varieties, due to high levels of monoterpenoids (geraniol, linalool and nerol), is highly distinct and has been greatly appreciated since ancient times. Muscat flavor determination in grapevine (Vitis vinifera L.) has up to now been studied by evaluating monoterpenoid quantity through QTL analysis. These studies have revealed co-localization of 1-deoxyxylulose-5-phosphate synthase (VvDXS) with the major QTL positioned on chromosome 5. The aim of the present study was to assess the connection between the positional candidate gene VvDXS and muscat flavor by investigating the nucleotide diversity of VvDXS ORF and its expression profiles in the grape berry. Association between VvDXS polymorphisms and muscat flavor was evaluated through a structured association analysis. A putative causal SNP responsible for a predicted non-neutral substitution was found to be significantly associated with muscat-flavored varieties. Moreover, muscat-like aromatic mutants displayed unique heterozygous non-synonymous mutations near the mutated site of Muscat genotypes. The relationship between the transcription profile of VvDXS alleles and monoterpenoid accumulation was investigated over an extended period of berry development. It is possible that a particular trend in expression rather than the level of expression ratio affects monoterpenoid accumulation in Moscato Bianco. In vivo experiments using transgenic tobacco and in vitro enzymatic assays suggest that the putative causal SNP raises monoterpenoid accumulation by changing the 3D protein structure and by increasing VvDXS activity in Muscat enzyme form

    An integrated approach to studying the positional candidate gene 1-deoxyxylulose-5-phosphate synthase (VvDXS) involved in Muscat flavor determination

    No full text
    Corresponding author: [email protected] audienceFragrance in table grapes and a persistent and complex aroma in wine are both sought after by the modern consumer. In particular, the floral flavor typical of Muscat varieties, due to high levels of monoterpenoids (geraniol, linalool and nerol), is highly distinct and has been greatly appreciated since ancient times. Muscat flavor determination in grapevine (Vitis vinifera L.) has up to now been studied by evaluating monoterpenoid quantity through QTL analysis. These studies have revealed co-localization of 1-deoxyxylulose-5-phosphate synthase (VvDXS) with the major QTL positioned on chromosome 5. The aim of the present study was to assess the connection between the positional candidate gene VvDXS and muscat flavor by investigating the nucleotide diversity of VvDXS ORF and its expression profiles in the grape berry. Association between VvDXS polymorphisms and muscat flavor was evaluated through a structured association analysis. A putative causal SNP responsible for a predicted non-neutral substitution was found to be significantly associated with muscat-flavored varieties. Moreover, muscat-like aromatic mutants displayed unique heterozygous non-synonymous mutations near the mutated site of Muscat genotypes. The relationship between the transcription profile of VvDXS alleles and monoterpenoid accumulation was investigated over an extended period of berry development. It is possible that a particular trend in expression rather than the level of expression ratio affects monoterpenoid accumulation in Moscato Bianco. In vivo experiments using transgenic tobacco and in vitro enzymatic assays suggest that the putative causal SNP raises monoterpenoid accumulation by changing the 3D protein structure and by increasing VvDXS activity in Muscat enzyme form

    Impact of Innovative and Creative leadership on Employee morale: A study in Bank Muscat

    No full text
    Abstract: The aim of this study is to investigate the impact of innovative and creative leadership on employee morale in Bank Muscat. Innovation leadership is a method and concept that combines a variety of leadership approaches to motivate and inspire people to produce new products, services, and ideas. People that are creative are innovators who can come up with new ideas that serve as the foundation for innovation. Job satisfaction, employee attitude, employee thoughts about his or her health, and happiness during his or her time at work are all examples of employee morale. The objectives includes identifying the various characteristics of innovative and creative leadership influencing employee morale and exploring how innovative and creative leadership effecting employee morale. Type of Research is quantitative method. Exploratory research was conducted. The research Respondent was 105 employees from the main branch of Bank Muscat. Sampling Procedure is Convenience Sampling. This paper examines the effect of creative and innovative leadership on employee morale, as well as the characteristics that influence leadership and employee morale of Bank Muscat workers. Keywords: Bank Muscat, Creative leadership, Employee morale, Innovative leadership, Job Satisfaction, Multiple Regression analysis. Title: Impact of Innovative and Creative leadership on Employee morale: A study in Bank Muscat Author: Ms. Noor Mahmood AlRawahi, Ms. Atka Suliman AlGhabshi, Ms. Kholood Hamood AlHasani, Ms.Noor Abdullah AlWahaibi, Dr.Anitha Ravikumar International Journal of Recent Research in Commerce Economics and Management (IJRRCEM) ISSN 2349-7807 Vol. 9, Issue 2, April 2022 - June 2022 Page No: 89-95 Paper Publications Website: www.paperpublications.org Published Date: 04-June-2022 DOI: https://doi.org/10.5281/zenodo.6613865 Paper Download Link (Source) https://www.paperpublications.org/upload/book/Impact%20of%20Innovative%20and-04062022-7.pdfInternational Journal of Recent Research in Commerce Economics and Management (IJRRCEM), ISSN 2349-7807, Paper Publications, Website: www.paperpublications.org

    Erratum: Public health digitalization in Europe: EUPHA vision, action and role in digital public health (European Journal of Public Health (2019) DOI: 10.1093/eurpub/ckz161)

    No full text
    In the original article, one of author Walter Ricciardi's affiliations (number 4) was incorrect. This has now been corrected in the online version of the article

    Education and Lung Cancer Among Never Smokers

    No full text
    Menvielle, G., Truong, T., Jellouli, F., Stüeker, I., Brenner, H., Field, J.K., Hosgood, H.D., Lan, Q., Landi, M.T., Hung, R.J., Lazarus, P., McLaughlin, J., Morgenstern, H., Muscat, J.E., Ruano-Ravina, A., Schwartz, A.G., Seow, A., Spitz, M.R., Tardon, A., Zhang, Z.-F., Luce, D

    Effects of Glutathione and Ascorbic Acid Addition on the CIELab Chromatic Characteristics of Muscat Ottonel Wines

    No full text
    AbstractGlutathione (GSH) and ascorbic acid (AA) are often added as antioxidants in wines for a better preservation of aroma. However, depending on the dosage of these substances, changes in colour may occur in the wines. The paper presents the effect of the addition of glutathione, with or without ascorbic acid, on the colour of Muscat Ottonel wines after 4 months of ageing in bottles. The dosage of ascorbic acid varied between 30 and 70 mg/l and that of glutathione between 10 and 100 mg/l, while in the samples where both glutathione and ascorbic acid were added the latter was kept constant at 30 mg/l. All wines contained the same amount of sulphur dioxide at the moment of addition, namely 80 mg/l total and 42 mg/l free, respectively. The analysis took into account 3 groups of samples: only with glutathione, only with ascorbic acid and with combination of glutathione and ascorbic acid. The CIELab colour parameters were determined and the colour components compared for the three groups and the control. The results showed that during storage the colour of wines evolved, parameter a showing in most samples a shift toward more red component. The most significant colour change was recorded for the samples treated only with glutathione, while the presence of ascorbic acid, with or without glutathione, lowered the value of parameter a. A synergistic effect in lowering the values of both parameter a and b was observed in the samples treated with combinations of ascorbic acid and glutathione at higher concentrations. The results suggest that a combination of glutathione and ascorbic acid may confer better stability of colour of white wines during storage

    Imam Salim b. Rashid and the Imamate revival in Oman 1331/1913 - 1338/1920

    No full text
    The principal aim of this thesis is to assess the performance of Imam Salim b.Rashid and the Imamate revival in Oman during the second decade of the 20th century. It presents biographical information about Imam Salim, with special reference to the military and political policies by which he established and consolided his Imamate in the Interior Province, and his relations with the Sultan and the latter's British supporters. An attempt is also made to explore the relationship between the Imam and the Omani tribes and to evaluate his administrative success. This thesis comprises eight chapters, and the introduction and conclusion. The introduction reviews the relevant literature on the topic. The first chapter describes the geographical setting and provides a historical background, relating to three principal matters: the rise of the Iba<;liyyah and the development of the Imamate in Oman; the events in Oman after Sd. Sa'id's death up to 1913; and the effects of the First World War. The second chapter seeks to give an account of the career of Imam Salim's life and the Imamate revival. The third chapter discusses the manner in which the Imam was elected, private and public allegiance (bay'ah) and the Imam's aims and policy programme. Chapter Four deals with the Imam's military operations and the spread of his authority over Oman. Chapter Five examines the attempts at negotiation between the Imam and the Sultan, and the role of the British Government and the local figures in this regard. Chapter Six is devoted to a discussion of the role of the tribes in support of Imam Salim, and the extent of the Imam's influence over these tribes. Chapter Seven assesses the Imam's administrative machinery, including the political system, the bureaucracy, education policy, and financial apparatus. Chapter Eight examines the causes behind the assassination of Imam Salim and the signing of the Treaty of al-Sib. In the conclusion, we present the findings of the research as they have emerged from the assessment of the course of events in Oman. We have said that the Omanis succeeded in reviving the Imamate and elected Imam Salim al-KharU~i who devoted his efforts to establish the foundations of the state, and peace prevailed in the country after the treaty of al-Sib in 1920

    Chemisorption on contaminated metals

    No full text
    PT: J; CR: ANDERSON PW, 1961, PHYS REV, V124, P41 DAVISON SG, 1968, INT J QUANTUM CHEM S, V2, P313 DAVISON SG, 1972, INT J QUANTUM CHEM, V6, P549 EINSTEIN TL, 1973, PHYS REV B, V7, P3629 EINSTEIN TL, 1978, SURF SCI, V75, L161 EINSTEIN TL, 1980, THEORY CEHMISORPTION, CH7 FAIRBAIRN WM, 1971, SURFACE SCI, V25, P587 GERLACH E, 1969, SURFACE SCI, V13, P446 GODWIN VE, 1973, SURF SCI, V34, P108 LAU KH, 1978, SURF SCI, V75, P69 MASUDA K, 1979, PHYS STATUS SOLIDI B, V92, K103 MUSCAT JP, 1978, PROG SURF SCI, V9, P1 MUSCAT JP, 1983, J PHYS C SOLID STATE, V16, P3641 NEWNS DM, 1969, PHYS REV, V178, P1123 UEBA H, 1980, PHYS STATUS SOLIDI B, V99, P763; NR: 15; TC: 18; J9: SURFACE SCI; PG: 10; GA: AAH42Source type: Electronic(1

    The spectrum of Ischemia-induced white matter injury varies with age

    No full text
    Stroke is a neurological condition that targets the whole range of the human population, from the pre-term infant to the elderly and is a major cause of death worldwide (Ingall 2004). During its lifespan, the brain's vulnerability to hypoxia-ischemia varies. Term infants who suffer this insult usually exhibit widespread neuronal injury in the cerebral cortex with a stroke-like distribution of damage (Deng 2008), whereas in pre-term infants immature oligodendrocytes and subplate neurons below the neocortex are most vulnerable and result in Periventricular Leukomalacia (PVL) (Back et al. 2007; McQuillen et al. 2005). The incidence of stroke decreases in young adulthood, but peaks again in the elderly. Moreover, the underlying pathological mechanisms that occur following ischemia are different at each stage. Experimental stroke research on stroke has traditionally focused on grey matter injury, but recent evidence indicates that white matter injury is a critical part of its pathophysiology. In this debilitating condition the mechanisms of ischemia-induced damage differ with age and all cellular components of white matter (axons, oligodendrocytes and astrocytes) are affected. This review paper focuses on the relative vulnerability to ischemia of white matter during the course of development and on our recent findings of how individual cellular components are affected during each stage.peer-reviewe
    corecore