6 research outputs found
Sexual dimorphism in visceral adiposity measures, parameters and biomarkers of metabolic syndrome among Hausa ethnic group in Kano, Nigeria
No full textEffect of aqueous seed extract of Nigella sativa on lead-induced cerebral cortex toxicity in Long Evans rats
No full textLead (Pb) is a widespread toxic metal found in the environment with potential danger to human health. It is used in the manufacture of batteries, metal products, paints and other domestic substances. This study investigated the effect of aqueous seed extract of Nigella sativa on leadinduced cerebral cortex toxicity in Long Evan’s rats. Twenty five Long Evans rats divided into five groups of five animals were used for the study. Group I received Distilled water, group II received aqueous seed extract of Nigella sativa (1000mg/kg), group III received lead (60mg/kg), group IV received lead (60mg/kg) followed by aqueous seed extract of Nigella sativa (1000mg/kg) and group V received lead (60mg/kg) followed by aqueous seed extract of Nigella sativa (500mg/kg) via oral intubation. Elevated Plus Maze (EPM) was used to study anxiety-like behaviour. Activities on the elevated plus maze showed that there was no statistically significant decreased rate of anxiety across the groups (P>0.05). The histology of the cerebral cortex of long Evans rats in group IV that received Lead (60 mg/kg) followed by aqueous seed extract of Nigella sativa (1000mg/kg) showed mild neuronal damage while the histology of group V animals that received lead (60mg/kg) followed by aqueous seed extract of Nigella sativa (500mg/kg) showed severe neuronal damage. It can be concluded that aqueous seed extract of Nigella sativa at high dose have more therapeutic effect than at low dose.Keywords: lead, Nigella sativa, elevated plus maze, cerebru
Attitude, perception and knowledge of menopause by women Ofkumana Chiefdom Kauru Local Government Area, Kaduna State, Nigeria
No full textNo Abstract
Sexual dimorphism in visceral adiposity measures, parameters and biomarkers of metabolic syndrome among Hausa ethnic group in Kano, Nigeria
No full textVisceral adipose tissue is considered the most important anatomic site of adipose tissue aggregation and is considered the hall mark of metabolic syndrome (MetS) phenotype. The aim of the study was to determine sexual dimorphism in visceral adiposity measures, parameters and biomarkers of metabolic syndrome among Hausa ethnic group in Kano, Nigeria. The study was a cross sectional study including 465 participants of Kano, with a mean age of 34.4 years and 32.0 years for males and females respectively. Systematic random sampling technique was employed for subject recruitment. Weight, height, waist circumference (WC) and body mass index BMI were obtained using standard protocol. Overnight fasting blood sample was obtained for high density lipoprotein cholesterol (HDL-c), total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDL-c), uric acid and adiponectin estimation using standard laboratory protocols. Visceral adipose tissue was estimated using visceral adiposity index (VAI) and WC. It was observed that VAI, FBG, HDL and TC were significantly higher in females. There was no significant sex difference in WC, TG, and LDL, Serum adiponectin, uric acid, systolic and diastolic blood pressure. In conclusion, the serum uric acid and adiponectin levels did not show sexual dimorphism. Only some of the MetS parameters are sexually dimorphic. While VAI was higher in females, WC did not show sexual dimorphism.Keywords: Biomarkers, metabolic syndrome indices, sexual dimorphism, visceral adiposit
Chronic Hepatotoxicity and Nephrotoxicity Study of Orally Administered Aqueous and Ethanolic Extracts of <em>Carica papaya</em> Seeds in Adult Wistar Rats
No full textSex estimation and sexual dimorphism analysis through hand anthropometry: Insights from a cross-sectional study
No full textOne crucial aspect of a forensic procedure is sex estimation during individual identification. Hand and its remains are usually among the common body parts found in scenes of mass disasters during forensic investigations. Hand outlines are also important in several biomedical fields such as prosthetics, plastic surgery, and ergonomics. This cross-sectional study was done to investigate sexual dimorphism and discriminate sex using hand and hand print dimensions of 283 male and 317 female subjects who were randomly selected. Bare hand measurement and bilateral hand prints were obtained using Vernier caliper, inked pad, and A4 plain paper. Data obtained were analyzed using SPSS version 23.0 IBM. Sexual dimorphism in all the hand dimensions and prints of both hands were observed. The binary logistic regression model showed that in the left hand, bare left-hand breadth (BLHB) was the single best variable to discriminate sex with a percentage accuracy of 69.5 %. Bare right-hand breadth (BRHB) was the best predictor in the right hand with a percentage accuracy of 71.8 %. The predicted probabilities of the binary logistic model (BLR) for the variables that contributed best to the prediction were analyzed using the receiver operating characteristic (ROC) curve. It was observed that the BLHB and BRHB had the highest area under the curve (above 0.5) in the hand and print variables respectively. Sexual dimorphism and sex determination were established in this study using hand dimensions and prints. The BLHB and BRHB were the best sex determinants in this study. Although the accuracies of sex estimation from both hands in this study are low, it does confirm and support previous reports of handbreadth being the best variable for sex estimation
