1,720,984 research outputs found
LA NOSTRA ESPERIENZA CON IL LATANOPROST NEL GLAUCOMA AD ANGOLO APERTO
No full textGli Autori, allo scopo di studiare la possibilità di applicare il Latanoprost ad una terapia antiglaucomatosa massimale, dimostratasi insufficiente a tenere sotto controllo la IOP, hanno esaminato 55 pazienti (109 occhi) affetti da GAA.
In base ai risultati preliminari ottenuti in questo studio (durata di osservazione: 9 mesi), si può affermare che il Latanoprost, somministrato in unica dose giornaliera, in associazione con altri 2 o 3 farmaci antiglaucomatosi come additivo o come sostituto di altro farmaco già in uso, si è dimostrato efficace nel ridurre ulteriormente la IOP (23,15%) già dopo un mese, risultando inoltre ben tollerato dal punto di vista locale e generale e consentendo così di evitare la miosi indotta dai parasimpaticomimetici e di semplificare lo schema terapeutico.With the aim of studying the possibility of application of Latanoprost to a maximum tolerated antiglaucomatous treatment which had proven to be unable to control IOP, 110 eyes suffering from Open-angle Glaucoma were examined. On the basis of the preliminary data obtained in an observation time of 9 months, it was established that Latanoprost, administered once daily at night-time, in association with 2 or 3 antiglaucomatous drugs as adjunctive of substitutive therapy, proved to be effective in furtherly reducing IOP (by 23.15%). Latanoprost was shown to be well tolerated both topically and systemically allowing thus to avoid miosis induced by parasympathomimetics and to semplify the therapeutic protocol
“ Importanza dei fattori emodinamici nel follow-up della patologia glaucomatosa”
No full textInfluenza dei fattori emodinamici nel glaucoma ad angolo apert
Timololo maleato: due anni di osservazioni nel glaucoma ad angolo aperto.
No full textThe Authors refer the results obtained in 96 patienrs suffering from open-angle glaucoma by means of treatment with timolol alone and ìn association with the usual antiglaucomatous drugs, in a period of two years. Besides the excellent topical tolerability of timolol, the indications for its use are pointe out
Le Beta-bloquant lévomoprolol dans le traitment du glaucome
No full textRésumé : Les auteurs illustrent les résultats favorables obtenus chez 44 malades ave c glaucome à angle ouvert au moyen d'un nouveau béta-bloquant en collyre , le lévomoprolol. On a employé une solution à 2 %. administrée I à 3 fois par jour pendant une période de plus de 9 mois. Les paramètres pris en considération ont été: la tension oculaire , l'examen biomicroscopique du segment antérieur. la sécrétion Iacryrnale , la kérato-esthésie, la tension artérielle générale et la fréquence du pouls. On a pu mettre en évidence que Je médicament provoque une hypotension oculaire significative et durable , que sa tolérabilité locale est optimale et qu'il n'y a pas d'effets collatéraux systémiques
Crioapplicazioni circonferenziali sull' occhio di coniglio. Modello sperimentale nella profilassi del distacco di retina.
No full textNella chirurgia del distacco di retina e nella sua profilassi sono d' uso comune le applicazioni criogeniche.
Nella presente ricerca gli A.A. valutano mediante la tecnica del blu di Evans, un colorante che si lega interamente all' albumina serica e che pertanto è indice della integrità delle barriere emato-oculari, la risposta vasomotoria e di apertura della barriera dopo brevi intervalli di tempo dai criotrattamenti retinici praticati con metodiche differentiIn surgery for retinal detachment and its prophylaxis are common use cryogenic applications.In this research the A.A. evaluated by the technique of Evans Blue, a dye that binds entirely to serum albumin and therefore is indicative of the integrity of the blood-ocular barrier, the vasomotor response and the opening of the barrier after short intervals of time by cryo-treatment of the retina with different methods
La brinzolamide come valida terapia sostitutiva nel glaucoma ad angolo aperto
No full textÈ stata valutata razione ipotensiva oculare a lungo termine (18 mesi) della brinzolamide, un inibitore dell' anidrasi carbonica di recente introduzione in terapia, in 50 pazienti affetti da GAA.
È stata riscontrata già dal primo mese una riduzione del 20.84% della IOP nell'81 % degli occhi esaminati che si è mantenuta costante per la durata dell'osservazione. Nell' Il % dei casi si sono verificati effetti collaterali locali e sistemici. Nell' 8ge degli occhi il farmaco si è dimostrato inefficace. Pertanto la brinzolamide rappresenta una valida alternativa nel trattamento del GAA.The long-term (18 months) oeular tension-Iowering effeet of brinzolarnide, a topieal earbonic anhydrase inhibitor reeently introdueed in the antiglaucomatous treatment, in 50 patients suffering from Open-angle Glaucoma was evaluated. Following one-month treatment a reduction in IOP of 22% was already observed in 81 % of the eyes examined. Such reduction was maintained throughout the observation time. In I 1% of cases topical side-effects were observed and treatment was diseontinued. In 8% of the eyes the drug was shown to be unable to control IOP. Brinzolamide represents a valuable alternative in the antiglaucomatous therapy
"Timolol, Betaxolol und Befunolol in der Glaukombehandlung, Untersuchungüber die bronchopulmonalen Effekte".
No full textTimolol, Betaxolol und Befunolol in der Glaukombehandlung, Untersuchungüber di
The combination latanoprost-timolol versus twice daily 0.50% timolol administration either associated or not with latanoprost: efficacy and tolerability in the Primary Open-Angle Glaucoma
No full textAims: To evaluate the ocular hypotensive effects and tolerability of the once daily fixed combination latanoprost-timolol versus twice daily 0.50% timolol associated or not with once daily latanoprost in patients suffering from Primary Open-Angle Glaucoma (POAG). Methods: We compared the effects of such a combination with those of 0.50% timolol alone twice daily in a group of 24 patients and with the effects of timolol 0.50% twice daily associated with once daily latanoprost in a second group of 20 patients with a follow-up of 24 months. Results: In the first group of patients after one month the Intraocular Pressure (IOP) was reduced from a mean of 19.93 to a 17.04 mmHg. This reduction remained stable with a mean value of 17.00 mmHg at the third month, of 16.49 mmHg at the sixth month, of 17.04 at the twelfth month, 16.00 at the eighteenth month, and of 15.86 mmHg in the twenty-fourth month. In the second group there was a statistically significant reduction from 19.4 to 16.84 mmHg after one month. This reduction remained constant with mean values of 16.47 at the sixth month, of 16.20 at the twelfth month and of 16.00 mmHg at the twentyfourth month of treatment. Conclusions: The once daily latanoprost-timolol combination was shown to furtherly reduce the Intraocular Pressure (IOP) (p=0.001) and to maintain under control the intraocular pressure for the observation period (24 months). Both topical and systemic side-effects were scarse and tolerability was good
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