916 research outputs found

    Moderate and High Suspicion Lesions on Multi-Parametric Magnetic Resonance Imaging (MRI) Can Predict Prostate Cancer in the Majority of Men

    No full text
    Rastinehad, A. R., Baccala, A. A., Chung, P.H., Kruecker, J., Xu, S., Locklin, J.K., Gates, S.P., Williams, H., Turkbey, B. I., Shih, J., Linehan, W.M., Glossop, N. D., Choyke, P.L., Wood, B. J., Pinto, P. (2010). Moderate and High Suspicion Lesions on Multi-Parametric Magnetic Resonance Imaging (MRI) Can Predict Prostate Cancer in the Majority of Men. Presented at: The Third International Symposium on Focal Therapy and Imaging of Prostate and Kidney Cancer, Washington, DC

    Strategic management and international HRM

    No full text
    International Human Resource Management provides a critical assessment of contemporary international HRM. Written by leading international scholars, this text explores the challenges confronting organizations as they seek to develop effective resourcing strategies in a global environment. International Human Resource Management is an excellent companion text for upper level undergraduate, postgraduates and MBA students studying international or comparative HRM

    Estimation of the pulmonary capillary transport function in isolated rabbit lungs.

    No full text
    Recently, we presented a method for estimating the pulmonary capillary volume and transport function based on the use of a reference indicator and two or more indicators that rapidly equilibrate (radially) with the tissue (i.e., the concentrations in the vascular and extravascular spaces at a given axial location are in equilibrium) during transit through the capillaries in a bolus-injection indicator dilution method (S. H. Audi, G. S. Krenz, J. H. Linehan, D. A. Rickaby, and C. A. Dawson. J. Appl. Physiol. 77: 332-351, 1994). The objectives of the present study were 1) to determine whether [14C]diazepam and [3H]alfentanil equilibrate sufficiently rapidly between the vascular space and tissue and with sufficiently different pulmonary extravascular mean residence times to be used in a single bolus to estimate the pulmonary capillary volume and transport function using this method and 2) to estimate the pulmonary capillary volume and transit time distribution in isolated perfused rabbit lungs. Both [14C]diazepam and [3H]alfentanil were found to be rapidly equilibrating indicators by the criteria that, over a wide range of flow rates, their respective venous effluent concentration curves were nearly congruent on a time scale normalized to the lung mean transit time for the reference indicator (fluorescein isothiocyanate dextran). In addition, at a given plasma albumin concentration, [14C]diazepam had a significantly longer extravascular mean residence time than [3H]alfentanil, e.g., at 6% plasma albumin concentration, the extravascular mean residence time of [14C]diazepam was more than twice that of [3H]alfentanil. On average, the estimated pulmonary capillary volume for a 2.7- kg rabbit was ~4.2 ml or ~44% of the total pulmonary vascular volume (9.5 ml). The relative dispersion of the pulmonary capillary transport function of the rabbit was ~90%

    Intraluminal Pressure Measurements during Esophageal Peristalsis : An Analysis of the Infused Catheter Technique

    No full text
    Normal esophageal function is determined by the ability of the esophagus to generate a sequential muscle contraction along its length during a swallow (peristalsis). The degree of muscle contraction is normally quantitated as a pressure force as measured by a water infused catheter placed distally in the esophageal body and attached proximally, to a pressure transducer. The purpose of this study is to determine whether this is presently an accurate recording system to measure esophageal pressure, and, if not, to make specific recommendations to improve these measurements

    An Experimental Study of Inverted Annular Flow Hydrodynamics Utilizing An Adiabatic Simulation

    No full text
    Knowledge of inverted annular flow hydrodynamics is essential for the proper analysis of low quality, film boiling transport phenomena. This thesis details an experimental study in which the stability, shape and disintegration/entrainment of the liquid jet-like core of inverted annular flow was investigated, utilizing an adiabatic simulation. This work was performed at Argonne National Laboratory, under the auspices of the U.S. Nuclear Regulatory Commission

    An empirical study of the repatriation of female managers : an emerging issue for European multinationals

    No full text
    In recent years, researchers have paid considerable attention to the issues of adjustment to international assignments, while comparatively little research activity has been paid to the topic of repatriation. Despite the growth in numbers of women in international management, very few studies have been conducted outside North America on the topic of repatriation of female corporate executives. This paper reports on the experiences of re-entry to home organizations and home countries by an exclusively senior sample of female international managers based in western Europe. The findings establish that the repatriation stage of an international career move may be even more stressful than expatriation. The findings also establish that female international managers experience more difficulties than their male counterparts because of their pioneering roles. The paper suggests that home-based mentors and access to networks while abroad are important factors in contributing to the successful repatriation of international managers

    Flow-induced vasodilation in the ferret lung

    No full text
    Chammas, Joseph H., David. A. Rickaby, Margarita Guarin, John H. Linehan, Christopher C. Hanger, and Christopher A. Dawson.Flow-induced vasodilation in the ferret lung. J. Appl. Physiol. 83(2): 495–502, 1997.—To examine the possibility that shear stress may be a pulmonary vasodilator stimulus, we studied the effect of changing blood flow on the diameters of small pulmonary arteries in isolated perfused ferret lung lobes. The arteries studied were in the ∼0.3- to 1.3-mm-diameter range, and the diameters were measured by using microfocal X-ray imaging. The diameters were measured at two flow rates, 10 and 40 ml/min, with the intravascular pressure in the measured vessels the same at the two flow rates as the result of venous pressure adjustment. The response to a change in flow was studied under both normoxic and hypoxic conditions. Hypoxia was used to elevate pulmonary arterial tone to increase the likelihood of detecting a vasodilator response. Under normoxic conditions, changing flow had little effect on the arterial diameters, but under hypoxic conditions the arteries were consistently larger at the higher flow than at the lower flow, even though the distending pressure was the same at the two flow rates. The results are consistent with the hypothesis that shear stress is a pulmonary vasodilator stimulus. </jats:p

    The management of expatriates : contemporary developments and future challenges

    No full text
    The rapid growth of international business at a time when many multinational companies (MNCs) are under increasing cost pressures has led these organisations to take a much closer look at their expatriation policies and practices. Faced with unprecedented levels of foreign competition at home and abroad, firms are beginning to recognise not only that international business is high on top management's list of priorities but that finding and nurturing the human resources required to implement an international strategy is of critical importance (Dowling et al., 1994). Much of the research on the management of expatriates currently available is drawn from research focused on North American multinationals. Adler (1997) commented that most research on international human resource management was concerned with American expatriates and continues to be written from an American rather than an international perspective. This introduction seeks to highlight the growth of research into expatriation to set the context for the five papers in this special edition that both add to some traditional areas of expatriate research and open up new fields relevant to this area of enquiry in international management and international business
    corecore