11,132 research outputs found
BEfree : Contextualização e desenvolvimento de um programa de intervenção em grupo para a Ingestão Alimentar Compulsiva e Obesidade
No full textPinto-Gouveia, J., Ferreira, C., Matos, M., & Carvalho, S. (2014). BEfree: contextualização e desenvolvimento de um programa de intervenção em grupo para a Ingestão Alimentar Compulsiva e Obesidade. Revista Factores de Risco, 34(9), 94-100. http://www.spc.pt/spc/default.aspx?redir=http://www.spc.pt/SPC/AreaCientifica/publicacoes/rfr/rfr.asp
From mathematics and education, to mathematics education
No full textThis chapter takes a historical view of the development of mathematics education, from its initial status as a business mostly managed by mathematicians to the birth of mathematics education as a scientific field of research. The role of mathematical communication is analyzed through the growth of journals and research conferences. Actions of internationalization and cooperation in facing instructional and educational problems are illustrated with reference to the journal L’Enseignement Mathématique and to ICMI. Curricular and methodological reforms in the 20th century which generated changes in school mathematics are considered. Starting from the acknowledgement that research in mathematics education demands more than the traditional focus on discussing curricular options at distinct grade levels, we identified several specialized clusters, debating specific issues related to mathematics education at an international level. We grouped the clusters into three main areas: relationships with psychology, the study of social, cultural and political dimensions, and the relevance of a theory for mathematics education
Bifunctional viscous nanovesicles co-loaded with resveratrol and gallic acid for skin protection against microbial and oxidative injuries
No full textThis work was partially supported by grants B102014-52872-R (Ministerio de Economia y Competitividad, Spain), which included FEDER funds, and 2014-SGR-938 (Generalitat de Catalunya, Spain).Vitonyte, J., Manca, M.L., Caddeo, C., Valenti, D., Peris, J.E., Usach, I., Nacher, A., Matos, M., Gutiérrez, G., Orrù, G., Fernàndez-Busquets, X., Fadda, A.M., Manconi, M
Hypertrophic cardiomyopathy in a dog: a systematic diagnostic approach
No full textA seven-year-old female neutered Parson Russel Terrier was referred for syncopal episodes. An electrocardiogram revealed paroxysmal atrial flutter followed by periods of sinus arrest, suggesting sick sinus syndrome. Echocardiography phenotype) with no signs of fixed or dynamic left ventricular outflow tract obstruction. Blood pressure, abdominal ultrasound, serum total thyroxin and thyroidstimulating hormone, and insulin-like growth factor-1 were all within normal limits. Cardiac troponin I was elevated (1.7 ng/mL, ref 7/mm2) associated with myocyte necrosis, but no evidence of myocyte vacuolisation or infiltrative myocardial disorders. These findings were compatible with myocardial ischaemic injury or acute lymphocytic myocarditis. Molecular analysis of canine cardiotropic viruses were negative. The dog developed refractory congestive heart failure and was euthanised 16 months later. Cardiac post-mortem examination revealed cardiomyocyte hypertrophy and disarray with diffuse interstitial and patchy replacement fibrosis, and small vessel disease, confirming HCM. We described a systemic diagnostic approach to an HCM phenotype in a dog, where a diagnosis of HCM was reached by excluding HCM phenocopies. 2023 The Author(s). Published by Elsevier B.V
Mappings between Banach spaces that preserve convergence of series
No full textWe know that a numerical series is absolutely convergent, if, and only if, it is unconditionally convergent. Dvoretzky and Rogers proved in 1950 that in any infinite dimensional Banach space there are unconditionally convergent series not absolutely convergent. This result was the origin of the development of the study of the linear mappings between Banach spaces sending unconditionally summable sequences into absolutely summable sequences (the Theory of absolutely Summing Mappings). The Nonlinear Theory started with Pietsch in 1983, when he presented a few results for scalar multilinear mappings and homogeneous polynomials defined on Banach spaces. In 1989 this author started the study of absolutely summing holomorphic mappings between Banach spaces. In a minicourse, thaught in 1997 at a Seminário Brasileiro de Análise, this author presented several results dated of 1996 and 1997 on nonlinear absolutely summing mappings (not necessarily holomorphic mappings) between Banach spaces. This course included an interesting characterization of regularly summing mappings f between Banach spaces, that is those mappings such that is absolutely summable whenever is absolutely summable. This result, applied in a convenient setting, implied a nice characterization result for nonlinear absolutely summing mappings, bearing striking similarities to the correspond result for linear absolutely summing mappings. These and other results, as well as historical references, can be found in M. C. Matos, Math. Nachr. 258, 71-89 (2003). In this work we introduce and develop the concept of uniformly regularly summing mappings between Banach spaces, allowing an interesting characterization of the uniformly absolutely summing mappings between Banach spaces, thus extending previous results on nolinear absolutely summing mappings. We also state a relation between uniform regularity and the Lipschitz property for mappings between Banach spaces
Biomimetic amorphous titania nanoparticles as ultrasound responding agents to improve cavitation and ros production for sonodynamic therapy
No full textConventional therapies to treat cancer often exhibit low specificity, reducing the efficiency of the treatment and promoting strong side effects. To overcome these drawbacks, new ways to fight cancer cells have been developed so far focusing on nanosystems. Different action mechanisms to fight cancer cells have been explored using nanomaterials, being their remote activation one of the most promising. Photo-and sonodynamic therapies are relatively new approaches that emerged following this idea. These therapies are based on the ability of specific agents to generate highly cytotoxic reactive oxygen species (ROS) by external stimulation with light or ultrasounds (US), respectively. Crystalline (TiO2) and amorphous titania (a-TiO2) nanoparticles (NPs) present a set of very interesting characteristics, such as their photo-reactivity, photo stability, and effective bactericidal properties. Their production is inexpensive and easily scalable; they are reusable and demonstrated already to be nontoxic. Therefore, these NPs have been increasingly studied as promising photo-or sonosensitizers to be applied in photodynamic/sonodynamic therapies in the future. However, they suffer from poor colloidal stability in aqueous and biological relevant media. Therefore, various organic and polymer-based coatings have been proposed. In this work, the role of a-TiO2 based NPs synthesized through a novel, room-temperature, base-catalyzed, sol-gel protocol in the generation of ROS and as an enhancer of acoustic inertial cavitation was evaluated under ultrasound irradiation. A novel biomimetic coating based on double lipidic bilayer, self-assembled on the a-TiO2-propylamine NPs, is proposed to better stabilize them in water media. The obtained results show that the biomimetic a-TiO2-propylamine NPs are promising candidates to be US responding agents, since an improvement of the cavitation effect occurs in presence of the developed NPs. Further studies will show their efficacy against cancer cells
Air-water flow features in skimming flow over steeply sloping stepped spillways
No full textSkimming flow over a stepped spillway is characterized by strong self-aeration downstream of the point of inception of air entrainment. In order to have a better understanding of the overall phenomenon of air entrainment and flow bulking, the main features of the self-aerated flow need to be evaluated. An experimental study has been carried out in a large-scale stepped chute assembled at the National Laboratory of Civil, Lisbon, in order to collect new air concentration data in skimming flows. In the present paper it is shown that some existing analytical models for predicting the air concentration distribution, as well as the development of the mean air concentration down the chute, compare fairly well with the experimental dat
LUP904787 Supplemental Material - Supplemental material for Angiotensin II receptor agonist antibodies are associated with microvascular damage in lupus nephritis
No full textSupplemental material, LUP904787 Supplemental Material for Angiotensin II receptor agonist antibodies are associated with microvascular damage in lupus nephritis by J M Mejia-Vilet, Y J López-Hernández, J I Santander-Vélez, M Trujeque-Matos, C Cruz, C A Carranza de la Torre, V Espinosa-Cruz, R Espinosa-González, N O Uribe-Uribe and L E Morales-Buenrostro in Lupus</p
The truth of personal names
No full textPortuguese-speakers, when asked about their personal names, often respond with a notion of the
‘truth of’ their names. Basing itself on ethnographic data collected by the author in Macao (southern
China), Bahia (Brazil), and Portugal, the article interprets this notion of truth as a form of ontological
weighing that postulates the unitariness of the person by reference to a subjection to a bureaucratic
order and to a cultural and linguistic universe associated to it
Valorisation of Salicornia ramosissima biowaste by a green approach – An optimizing study using response surface methodology
No full textThe purpose of this study was to optimize the extraction of antioxidants from Salicornia ramosissima by-product through Response Surface Methodology (RSM). The impacts of time (10–60 min) and temperature (40–80 °C) in total phenolic content (TPC) and antioxidant/antiradical activity were assessed. The optimal extract was attained at the binomial 80 °C/10 min and characterized regarding phenolic composition, pigments quantification, radicals quenching capacity, anti-acetylcholinesterase (AChE) activity, and cell viability effects. The optimal extract was characterized by low carotenoids content (8.15 μg/g on dry weight (dw)) and high amounts of hydroxycinnamic acid derivatives (23.12 mg/g dw). A remarkable scavenging efficiency was observed, particularly for HOCl (IC50 = 27.61 μg/mL) and ONOO− (IC50 = 47.32 μg/mL). No adverse effects were detected on HaCaT and HFF-1 viability up to 1000 μg/mL. Additionally, the neuroprotective properties of the optimal extract were demonstrated by AChE inhibition (32.34% at 1000 μg/mL). This study encourages the sustainable recovery of antioxidants from the undervalued biowaste of S. ramosissima as a new raw material for different industries
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