603 research outputs found
Onychomycosis
No full textSeebacher C, Brasch J, Abeck D, et al. Onychomycosis. Mycoses . 2007;50(4):321-327.The guideline on onychomycosis, as passed by the responsible German medical societies, is presented in the present study
Onychomykose
No full textSeebacher C, Brasch J, Abeck D, et al. Onychomycosis. Journal der Deutschen Dermatologischen Gesellschaft (JDDG). 2007;5(1):61-66.Dt. Version erschienen u.d.T.: Onychomykose ([https://doi.org/10.1111/j.1610-0387.2007.06134_supp.x]( https://doi.org/10.1111/j.1610-0387.2007.06134_supp.x)
Tinea capitis: ringworm of the scalp
No full textSeebacher C, Abeck D, Brasch J, et al. Tinea capitis: ringworm of the scalp. Mycoses . 2007;50(3):218-226.The guideline tinea capitis, as passed by three German medical societies, is presented in the present study
Tinea Capitis
No full textSeebacher C, Abeck D, Brasch J, et al. Tinea Capitis. Journal der Deutschen Dermatologischen Gesellschaft (JDDG). 2006;4(12):1085-1091
Candidose der Haut
No full textSeebacher C, Abeck D, Brasch J, et al. Candidose der Haut. Journal der Deutschen Dermatologischen Gesellschaft (JDDG). 2006;4(7):591-596
Dermatomycoses and inflammation : the adaptive balance between growth, damage, and survival
No full textDermatomycosis is characterized by both superficial and subcutaneous infections of keratinous tissues and mucous membranes caused by a variety of fungal agents, the two most common classes being dermatophytes and yeasts. Overall, the stepwise process of host infection is similar among the main dermatomycotic species; however, the species-specific ability to elicit a host reaction upon infection is distinct. Yeasts such as Candida albicans elicit a relatively low level of host tissue damage and inflammation during pathogenic infection, while dermatophytes may induce a higher level of tissue damage and inflammatory reaction. Both pathogens can, however, manipulate the host's immune response, ensuring survival and prolonging chronic infection. One common element of most dermatomycotic infections is the disease burden caused by inflammation and associated signs and symptoms, such as erythema, burning and pruritus. There is a strong clinical rationale for the addition of a topical corticosteroid agent to an effective antimycotic therapy, especially in patients who present with inflammatory dermatomycoses (e.g., tinea inguinalis). In this review, we aim to compare the pathogenesis of common dermatomycotic species, including Candida yeasts (Candida albicans), dermatophytes (Trichophyton, Epidermophyton or Microsporum species), and other pathogenic yeasts (Malassezia), with a special focus on unique species-specific aspects of the respective infection processes, the interaction between essential aspects of pathogenic infection, the different roles of the host inflammatory response, and the clinical consequences of the infection-related tissue damage and inflammation. We hope that a broader understanding of the various mechanisms of dermatomycoses may contribute to more effective management of affected patients
Trade Credit and Personalismo in Latin America
No full textPersonalismo is a behavioral norm which is generally accepted as an important Latin American Cultural trait.11John P. Gillian, “The Middle Segments and Their Values” in Latin American Pollitics. ed. Robert D. Tomasek (Garden City: Doubleday and Company, 1996), pp. 23–40. It has been discussed as having a primary influence on the political and business systems of this area. Its influence on a business system and trade credit is the concern of this article.Parts of a diagnostic research study on the operational problems of the trade credit system in El Salvador22John J. Brasch, A Descriptive Analysis of the Trade System of El Salvador, Doctoral Dissertation (St. Louis, Graduate School of Business Administration—Washington University), 1970. serve as the primary basis for the discussion that follows. The relevant findings of this El Salvador study with respect to personalismo were subsequently confirmed through lengthy interviews in Mexico, Guatemala, Costa Rica, and Honduras, thus warranting in subsequent comments, guarded generalization for all of Latin America.© 1973 JIBS. Journal of International Business Studies (1973) 4, 31–41
Corrigendum: Guideline: vulvovaginal candidosis (AWMF 015/072), S2k (excluding chronic mucocutaneous candidosis) (vol 58, pg 1, 2015)
No full textMendling W, Brasch J, Cornely OA, et al. Corrigendum: Guideline: vulvovaginal candidosis (AWMF 015/072), S2k (excluding chronic mucocutaneous candidosis) (vol 58, pg 1, 2015). Mycoses . 2015;58(5):324
Polysensitization and increased susceptibility in contact allergy: a review
No full textGenetic factors presumably play a role in contact allergy (CA). There is, however, a lack of conclusive evidence from clinical studies. This may be on account of the strongly competing or modifying impact of exogenous factors, namely the potency of allergens and the intensity of exposure, and the fact that - in principle - everybody can be sensitized. Regarding phenotype, in contrast, polysensitization (PS) seems to indicate a subset of individuals at greater risk. In human sensitization experiments with dinitrochlorobenzene, induction was facilitated in PS, and elicitation enhanced. Recent clinical epidemiological data, taking confounders for PS, such as age, sex, and other skin diseases into account, demonstrated the following: (i) PS was the greatest risk factor to be sensitized to a number of (even weak) index allergens, indicating higher susceptibility on the level of induction; (ii) patch test reactions in PS patients were generally stronger indicating higher susceptibility on the level of elicitation. These findings are complemented by reports on polymorphisms of TNF-alpha and IL-16 in PS patients. Future studies on the genetics of CA should be performed in subgroups with PS, focussing on polymorphisms relevant for CA-specific and nonspecific (inflammatory) processes
Reproducibility of irritant patch test reactions to sodium lauryl sulfate in a double-blind placebo-controlled randomized study using clinical scoring - Results from a study group of the German Contact Dermatitis Research Group (Deutsche Kontaktallergie-Gruppe, DKG)
No full textBrasch J, Becker D, Effendy I. Reproducibility of irritant patch test reactions to sodium lauryl sulfate in a double-blind placebo-controlled randomized study using clinical scoring - Results from a study group of the German Contact Dermatitis Research Group (Deutsche Kontaktallergie-Gruppe, DKG). Contact Dermatitis . 1999;41(3):150-155.Reading of doubtful patch test reactions can be improved by comparing them to defined negative, allergic and irritant controls. For the latter, an irritant patch test is needed that gives sufficiently reproducible results. In our double-blind, placebo-controlled. randomized study, we have analysed the synchronous reproducibility of patch tests with 0%, 0.0625%, 0.125%, 0.25%, 0.5% and 1.0% sodium lauryl sulfate (SLS). Tests and readings were done according to ESCD guidelines. 139 patients (75 women, 64 men) 18 to 77 years old were tested. The % of positive patients as well as the % of reproducible positive reactions increased with rising concentrations of SLS to a maximum of approximately 90% and 85%, respectively with 1 % SLS. Time courses of reactions were also related to the concentration of SLS: with 1 % SLS, plateau-type time courses were most common (65%), followed by decrescendo- (23%) and crescendo-type reactions (12%). With 1% SLS, very similar mild to moderate reactions were obtained on days 2 and 3. The reaction threshold and reproducibility of tests were not related to age and sex of patients or to their own assessment of skin irritability. We conclude that 1% SLS is appropriate for an irritant patch test that gives sufficiently reproducible results
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