1,219 research outputs found

    Understanding student responses to gender-based violence on campus: negotiation, reinscription and resistance

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    This chapter presents findings from the ‘Stand Together’ action research project at the University of Lincoln (UOL), one of the first bystander intervention (BI) programmes designed to challenge gender-based violence (GBV) in a UK university. The research accompanying this project investigated student attitudes to GBV and the potential of prevention education. The focus of this chapter is on two sites which emerged in student accounts as key spaces where acts of GBV occur, as well as where sexist and heteronormative gender norms are re-inscribed, negotiated and resisted - social media and the night-time economy (NTE)

    FIGURE 3 in Rediscovery of Impatiens parvifolia and reinstatement of I. omissa (Balsaminaceae) in India

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    FIGURE 3. Impatiens omissa: A-B. Inflorescence, C. Lateral sepals, D–E. Lower sepal, F. Dorsal petal, G–H. Lateral united petal, I. Pistil and stamen, J. Fruit, K. Seeds.Published as part of Anirudhan, Anitha Melesuparambil, Mani, Bince, Gnanasekaran, Gunadayalan & Thomas, Sinjumol, 2023, Rediscovery of Impatiens parvifolia and reinstatement of I. omissa (Balsaminaceae) in India, pp. 269-277 in Phytotaxa 589 (3) on page 273, DOI: 10.11646/phytotaxa.589.3.5, http://zenodo.org/record/777699

    FIGURE 5 in Rediscovery of Impatiens parvifolia and reinstatement of I. omissa (Balsaminaceae) in India

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    FIGURE 5. Impatiens parvifolia: A–B. Inflorescence, C. Lateral sepals, D–E. Lower sepal, F. Dorsal petal, G–H. Lateral united petal, I. Pistil and stamen, J. Fruit, K. Seeds.Published as part of Anirudhan, Anitha Melesuparambil, Mani, Bince, Gnanasekaran, Gunadayalan & Thomas, Sinjumol, 2023, Rediscovery of Impatiens parvifolia and reinstatement of I. omissa (Balsaminaceae) in India, pp. 269-277 in Phytotaxa 589 (3) on page 275, DOI: 10.11646/phytotaxa.589.3.5, http://zenodo.org/record/777699

    sj-docx-1-dst-10.1177_19322968221103561 – Supplemental material for Explainable Machine Learning for Real-Time Hypoglycemia and Hyperglycemia Prediction and Personalized Control Recommendations

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    Supplemental material, sj-docx-1-dst-10.1177_19322968221103561 for Explainable Machine Learning for Real-Time Hypoglycemia and Hyperglycemia Prediction and Personalized Control Recommendations by Christopher Duckworth, Matthew J. Guy, Anitha Kumaran, Aisling Ann O’Kane, Amid Ayobi, Adriane Chapman, Paul Marshall and Michael Boniface in Journal of Diabetes Science and Technology</p

    Symposium #26

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    Opening Remarks: Edward C. Halperin, M.D., M.A. They just changed the recommendations for screening mammography... again. Now what should I do?: Anitha Srinivasan Dad, your toenails are disgusting. Are you going to do something? The management of onychomycosis: Michael J. Trepal Panel Discussion: Moderated by Edward C. Halperin, M.D., M.A. One doctor says take a proton pump inhibitor for my gastric reflux. Then I read that these drugs increase the risk of dementia. Should I take them or not?: by Mill Etienne, M.D., M.P.H., FAAN, FAES; Edward Lebovics, M.D. Doctors are always taking a family history as part of their routine medical history and physical. What do they actually do with that information? What kind of records should a family retain about their medical history?: by Lori Solomon, M.D., M.P.H. Q & A: Hosted by Alan Kadish, M.D..https://touroscholar.touro.edu/ninety_minutes/1003/thumbnail.jp

    Nanocapsules with stimuli-responsive moieties for controlled release employing light and enzymatic triggers

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    The development of stimuli-responsive nanomaterials, that possess tailored functional properties for the release of specific compounds, is of particular interest. To this extent, controlling the release of molecules at the desired target is an important parameter to regulate chemical and/or biological reactions at a more profound level in a wide variety of applications. In the present work, we report on the development of dual-responsive thiourethane-urethane nanocapsules synthesizedviaan interfacial polymerization reaction executed at the droplet interface using the inverse miniemulsion technique. Evidenceviamorphological and controlled release investigations indicate that our nanocapsules are able to encapsulate hydrophilic compounds with high efficiency in their aqueous core and allow for its selective release upon exposure to UV light and the enzyme esterase. Moreover, we demonstrate the efficient encapsulation of the fragrance molecule geranyl acetate and the anticancer drug doxorubicin. For the latter, we demonstrate its apoptotic effect after being released in MCF 7 breast cancer cells. Overall, these nanocapsules can be used for a wide variety of applications where a selective release of the payload is desired.S. S. is an SB PhD Fellow at the FWO (Research Foundation Flanders). S. K. P. acknowledges BOF funding from Hasselt University. This work is supported by Hasselt University and the Research Foundation Flanders (FWO Vlaanderen; Hercules project AUHL/15/2 - GOH3816N). The authors are thankful to Prof. M. Van Bael for access to the DLS device.Pramanik, SK; Ethirajan, A (corresponding author), Hasselt Univ, Inst Mat Res IMO, Wetenschapspk 1 & Agoralaan D, B-3590 Diepenbeek, Belgium; IMEC, Associated Lab IMOMEC, Wetenschapspk 1, B-3590 Diepenbeek, Belgium; CSIR Cent Salt & Marine Chem Res Inst, Bhavnagar 364002, Gujarat, India. [email protected]; [email protected]

    PEGylating poly(p-phenylene vinylene)-based bioimaging nanoprobes

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    Hypothesis: Conjugated polymer nanoparticles (CNPs) have attracted considerable attention within bioimaging due to their excellent optical properties and biocompatibility. However, unspecific adsorption of proteins hampers their effective use as advanced bioimaging probes. Controlled methodologies made possible tailor-made functional poly(p-phenylene vinylene), enabling one-pot synthesis of CNPs containing functional surface groups. Hence, it should be feasible to PEGylate these CNPs to tune the uptake by cell lines representative for the brain without imparting their optical properties. Experiments: CNPs consisting of the statistical copolymer 2-(50-methoxycarbonylpentyloxy)-5-methoxy-1,4-phenylenevinylene and poly(2-methoxy-5-(30,70-dimethoxyoctyloxy)-1,4-phenylenevinylene) were fabricated by miniemulsion solvent evaporation technique. Surface carboxylic acid groups were used to covalently attach amine-terminated polyethylene glycol (PEG) of different molecular weights. We investigated the effect of grafting CNPs with PEG chains on their intrinsic optical properties, protein adsorption behavior and uptake by representative brain cell lines. Findings: PEGylation did not affect the optical properties and biocompatibility of our CNPs. Moreover, a significant decrease in protein corona formation and unspecific uptake in central nervous system cell lines, depending on PEG chain length, was observed. This is the first report indicating that PEGylation does not affect the CNPs role as excellent bioimaging tools and can be adapted to tune biological interactions with brain cells. (C) 2020 Elsevier Inc. All rights reserved.Support for confocal microscopy was given by Prof. dr. Marcel Ameloot and Dr. Hannelore Bove. Cells were kindly provided by Prof. dr. Annelies Bronckaers, Dr. Jo Mailleux and dra. Jasmine Vanmol. Technical support was given by Huguette Penxten, Christel Bocken and Erik Royackers. Dr. Neomy Zaquen is acknowledged for the synthesis of the conjugated polymers. MP is grateful for funding from the IWT (Agentschap voor Innovatie door Wetenschap en Technologie). SS is an SB PhD Fellow at the Research Foundation Flanders (FWO). The work was funded by the Belgian Charcot Foundation. TJ is grateful for funding from the FWO in the form of an Odysseus grant. This work was supported by Hasselt University and the Research Foundation Flanders (FWO Vlaanderen; Hercules project AUHL/15/2 -GOH3816N). Additional support from BELSPO in the form of the interuniversity attraction pole (IAP) program P7/05: Functional Supramolecular Systems is kindly acknowledged. We further acknowledge the Hercules Foundation for the project (LC-MS@UHasselt: Linear Trap QuadrupoleOrbitrap mass spectrometer.Ethirajan, A (corresponding author), Hasselt Univ, Inst Mat Res, Wetenschapspk 1, B-3590 Diepenbeek, Belgium. [email protected]
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