3,367 research outputs found
Employer and labour provider perspectives on Eastern European migration to the UK
No full textIn a relatively short space of time Eastern Europe has become one of the principal source regions of migrants to the UK and citizens from these states now constitute some of the largest foreign-born populations in the country. This paper focuses on these trends from the perspective of UK employers and labour providers. Three main topics are covered; 1. The function served by East European migrant labour in the UK labour market and how this has changed over time. 2. Employers’ motivations for engaging with East European migrant labour. 3. The migration channels that shape how East European labour is sourced by UK employers. The findings demonstrate how the perspectives and practices of employers and recruiters can play an important role in influencing how East European labour migration flows to the UK are represented and produced
Drug diffusion, integration, and stability of nanoengineered drug-releasing implants in bone ex-vivo
No full textAbstract not availableShafiur Rahman, Karan Gulati, Masakazu Kogawa, Gerald J. Atkins, Peter Pivonka, David M. Findlay and Dusan Losi
Drug-releasing nano-engineered titanium implants: therapeutic efficacy in 3D cell culture model, controlled release and stability
No full textAbstract not availableKaran Gulati, Masakazu Kogawa, Matthew Prideaux, David M. Findlay, Gerald J. Atkins, Dusan Losi
Calcitonin
No full textEndocrinology: Adult and Pediatric,Volume 1David M. Findlay, Patrick M. Sexton, and T. John Marti
First Australian report of vitamin D-dependent rickets type I
No full textNobuaki Ito, Alexia S Peña, Shiree Perano, Gerald J Atkins, David M Findlay, Jennifer J Coupe
Relationship between serum RANKL and RANKL in bone
No full textIt is now well accepted that the molecule receptor activator of NFκB ligand (RANKL) and osteoprotegerin play key roles in regulating physiological and pathological bone turnover. There are a large number of published reports of circulating RANKL levels in both health and pathology. However, interpretation of these data has been elusive, and the relationship between circulating RANKL and RANKL levels in bone is still not clear. This review explores this subject, documenting the possible origins of circulating RANKL and suggesting additional information that is required before serum RANKL levels can provide useful diagnostic or research information.D. M. Findlay, G. J. Atkin
Antiviral potential of cathelicidins
No full textThe global burden of morbidity and mortality arising from viral infections is high; however, the development of effective therapeutics has been slow. As our understanding of innate immunity has expanded over recent years, knowledge of natural host defenses against viral infections has started to offer potential for novel therapeutic strategies. An area of current research interest is in understanding the roles played by naturally occurring cationic host defense peptides, such as the cathelicidins, in these innate antiviral host defenses across different species. This research also has the potential to inform the design of novel synthetic antiviral peptide analogs and/or provide rationale for therapies aimed at boosting the natural production of these peptides. In this review, we will discuss our knowledge of the antiviral activities of cathelicidins, an important family of cationic host defense peptides, and consider the implications for novel antiviral therapeutic approaches
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