145 research outputs found
sj-docx-1-tdo-10.1177_00494755211049031 - Supplemental material for Intestinal Spirochaetosis-A case series from the developing world
No full textSupplemental material, sj-docx-1-tdo-10.1177_00494755211049031 for Intestinal Spirochaetosis-A case series from the developing world by Zain Majid, Ghazi Abrar, Hina Ismail, Muhammad Danish, Muhammad Mubarak and Nasir Luck in Tropical Doctor</p
sj-docx-2-tdo-10.1177_00494755211049031 - Supplemental material for Intestinal Spirochaetosis-A case series from the developing world
No full textSupplemental material, sj-docx-2-tdo-10.1177_00494755211049031 for Intestinal Spirochaetosis-A case series from the developing world by Zain Majid, Ghazi Abrar, Hina Ismail, Muhammad Danish, Muhammad Mubarak and Nasir Luck in Tropical Doctor</p
Hina Hanta: The Circle of Metacognition
No full textThe articles of this dissertation combine to make an autobiographical written study, a Scholarly Personal Narrative of life writing. The work culminates with a research study by way of a Talking Circle among a group of scholarly elders who gathered to share guidance for Indigenous scholars navigating colonial structures in our sites of knowledge production. Utilizing a Mixed-Methods approach, this sharing was transcribed, coded, and examined via Western thematic analysis. Through stories, casting an international light, analyses reveal a work of written guidance not only for Indigenous scholars, but also for education stakeholders, for those claiming diversity, equity, and inclusion, and for sites of knowledge production globally. The author walks alongside the memories in her mind. Through becoming a mother, she discovers a path of healing located in the philosophy her grandmother taught her as a child: Hina Hanta, a path of stories that tell who we are. Hina Hanta is her paradigm and Talking Circles hearken back to ancient times when stories were shared through Indigenous ways of being, since time immemorial (Wilson, 2008). Sharing circles, Talking Circles, are about providing experiences based on ancient ceremonial practices.Educational Leadership and Policy StudiesDoctor of Philosophy (PhD
Lunch & Keynote Speaker
No full textHina Shamsi is the Director of the ACLU’s National Security Project, which is dedicated to ensuring that U.S. national security policies and practices are consistent with the Constitution, civil liberties, and human rights. She has litigated cases upholding the freedoms of speech and association, and challenging targeted killing, torture, unlawful detention, and post-9/11 discrimination against racial and religious minorities. Her work includes a focus on the intersection of national security and counterterrorism policies with international human rights and humanitarian law. She previously worked as a Staff Attorney in the National Security Project and was the Acting Director of Human Rights First\u27s Law & Security Program. She also served as Senior Advisor to the U.N. Special Rapporteur on Extrajudicial Executions. Hina appears regularly in the media and has been quoted as a national security expert by numerous outlets including The New York Times, The Washington Post, The Associated Press, and Reuters, and has appeared on MSNBC, Fox News, CNN, NPR, ABC News, and the BBC. She is the author and coauthor of publications on targeted killing, torture, and extraordinary rendition, and has monitored and reported on the military commissions at Guantánamo Bay. She is also a lecturer-in-law at Columbia Law School, where she teaches a course in international human rights
A relevance theoretic approach to the particle 'hina' in Koine Greek
No full textThis thesis uses insights from a modern theory of communication, Relevance Theory, to examine the function of certain particles - in particular the conjunction hina - in Koine Greek. This particle has been regarded from the time of Classical Greek as an introducer of purpose clauses and so has been thought to have the lexical meaning of ‘in order that.’ More recently, however, scholars have recognised that in the New Testament at least, no more than 60% of the uses of hina merit such a translation, with a considerable number of independent clauses being introduced by this particle also. Apart from the New Testament it is the case that pagan writers of Koine used this particle to introduce a wider range of clauses than merely those with a telic relationship to the main clause of the sentence. This is particularly noticeable in the Discourses of Epictetus, a philosopher who taught in the latter half of the first century of the Christian era. In addition, Dionysius of Halicarnassus, a notable critic of literary style and the historian Polybius, both writing within the Koine period used hina to introduce indirect commands and noun clauses as well as purpose clauses. The frequency of such uses (approximately 10% of all the instances of this particle) in their writings is considerably less than that of Epictetus, but those uses are nevertheless present in their works. Since iota-nu-alpha was used for this wider range of clauses by pagan, non-Jewish authors, some of whom spoke Greek as their first language, it seems extremely implausible to attribute such use to the incompetence of the implied authors of the New Testament, or ‘Semitic interference’. Since the many instances of non-telic hina in the New Testament are identified with reference to the context in which they occur, the telic instances should also be deduced from such context. I claim that the function of this particle is not to introduce a purpose clause nor does it have a fixed lexical meaning of ‘in order that’, but rather that it alerts the reader to expect an interpretation of the thought of the speaker or implied author. Of course in many instances a clause introduced by hina will be a purpose clause, but this is inferred from context rather than solely from the presence of this particle. This thesis proposes a unified account of the function of hina which fits the developing pattern of the language and relates it to the particle 'hina', and provides a theoretical basis for its use as an indicator of speaker or subject’s thought, thus enabling a reader to re-examine biblical texts whose interpretation has been problematic to date.EThOS - Electronic Theses Online ServiceGBUnited Kingdo
A Relevance Theoretic approach to the particle 'hina' in Koine Greek
No full textThis thesis uses insights from a modern theory of communication, Relevance Theory, to
examine the function of certain particles - in particular the conjunction hina - in Koine
Greek. This particle has been regarded from the time of Classical Greek as an introducer
of purpose clauses and so has been thought to have the lexical meaning of ‘in order that.’
More recently, however, scholars have recognised that in the New Testament at least, no
more than 60% of the uses of hina merit such a translation, with a considerable number
of independent clauses being introduced by this particle also. Apart from the New
Testament it is the case that pagan writers of Koine used this particle to introduce a
wider range of clauses than merely those with a telic relationship to the main clause of
the sentence. This is particularly noticeable in the Discourses of Epictetus, a philosopher
who taught in the latter half of the first century of the Christian era. In addition,
Dionysius of Halicarnassus, a notable critic of literary style and the historian Polybius,
both writing within the Koine period used hina to introduce indirect commands and noun
clauses as well as purpose clauses. The frequency of such uses (approximately 10% of
all the instances of this particle) in their writings is considerably less than that of
Epictetus, but those uses are nevertheless present in their works. Since iota-nu-alpha was used for
this wider range of clauses by pagan, non-Jewish authors, some of whom spoke Greek as
their first language, it seems extremely implausible to attribute such use to the
incompetence of the implied authors of the New Testament, or ‘Semitic interference’.
Since the many instances of non-telic hina in the New Testament are identified with
reference to the context in which they occur, the telic instances should also be deduced
from such context. I claim that the function of this particle is not to introduce a purpose
clause nor does it have a fixed lexical meaning of ‘in order that’, but rather that it alerts
the reader to expect an interpretation of the thought of the speaker or implied author. Of
course in many instances a clause introduced by hina will be a purpose clause, but this is
inferred from context rather than solely from the presence of this particle. This thesis
proposes a unified account of the function of hina which fits the developing pattern of the
language and relates it to the particle o(/ti, and provides a theoretical basis for its use as
an indicator of speaker or subject’s thought, thus enabling a reader to re-examine biblical
texts whose interpretation has been problematic to date
Hina Jilani on her Satyagraha for Women’s Rights in Pakistan
No full text This piece is based on a conversation the author had with lawyer and human rights activist from Pakistan, Hina Jilani, in May 2016. It captures Jilani’s account of the ‘Satyagraha’ she has waged in her lifetime for the rights of women in her country; and as she narrates her story, she interweaves it with the ‘Satyagraha’ that shaped the women’s movement in Pakistan. One can read here about Jilani’s struggle for truth, for a human rights consciousness in a political climate of military regime; and how she challenged courts in the country to step outside the realm of conventional law and extend justice to women and girls. And in the process, learn that her struggle for truth has been intertwined with that of the women’s movement in the country. </jats:p
Interview with … : Dipo Faloyin, author of Africa Is Not A Country
No full textIn a departure from our usual format, the Editorial Collective is publishing an interview with Dipo Faloyin – author of Africa Is Not A Country: Breaking stereotypes of modern Africa (Faloyin, 2022) – alongside the Spotlight On … article by Hina Robinson on the importance of using Faloyin’s book in the geography classroom (see pages 29–32)
A neuron-glial model of exosomal release in the onset and progression of Alzheimer's disease
No full textExosomes are nano-sized extracellular vesicles that perform a variety of biological functions linked to the pathogenesis of various neurodegenerative disorders. In Alzheimer's disease (AD), for examples, exosomes are responsible for the release of Aβ oligomers, and their extracellular accumulation, although the underpinning molecular machinery remains elusive. We propose a novel model for Alzheimer's Aβ accumulation based on Ca2+-dependent exosome release from astrocytes. Moreover, we exploit our model to assess how temperature dependence of exosome release could interact with Aβ neurotoxicity. We predict that voltage-gated Ca2+ channels (VGCCs) along with the transient-receptor potential M8 (TRPM8) channel are crucial molecular components in Alzheimer's progression
Experimental and analytical tools for rapid development of digital imaging-based elasto-tomography technology
No full textBreast cancer is the second most common cancer in the world and has the highest cancer mortality rate in women. Presently, 1 of every 4 women carry an increased risk of breast cancer, of which, 6% are below the minimum screening age of 45. Early detection via regular screening not only reduces mortality rates, but also decreases overall treatment expenditure. X-ray mammography is the clinical standard breast cancer screening technique. However, due to significant limitations, such as unacceptable rates of false positive and false negative results, exposure to ionizing radiation, and discomfort and pain due to the compression of the breast it is not recommended for women under 45 years of age. These women also often have denser breast tissues, which further reduce mammography efficacy and diagnostic capability.
Digital imaged elasto-tomography (DIET) has been developed to overcome some of the limitations of current techniques and mammography in particular. The digital imaged elasto-tomography (DIET) concept is based on non-invasive, pain-free, vibration based analysis of local tissue stiffness, a form of elastographic reconstruction from actuation motion. This technique enables early detection of breast cancer, as it is not restricted in the ages of women who could utilize it for screening. Thus, combined with effective treatment, it could reduce mortality, particularly for younger women. More specifically, recent analysis showing annual mammography down to 40 years of age would save many more lives than current screening, indicating a system like DIET, safely offering screening to any age, could significantly improve breast cancer mortality. DIET is a novel method and technology, but is not yet at a stage suitable for a large randomised clinical trial. However, its development could be significantly enhanced by a series of tools to improve the speed and repeatability of DIET technology development. Currently, DIET is developed primary by executing pilot clinical testing of human volunteers. This experimental approach is slow, not repeatable as technology progresses and thus not necessarily optima, as well as placing a burden on diagnosed volunteer patients. In particular, repeating trials is not possible, limiting the ability to accurately assess technological changes.
The productivity of DIET technology development could thus be enhanced in three main areas: a) development of realistic and accurate tissue mimicking breast phantoms; b) validation of the surface measurement algorithms to quantify their error and thus to quantify the limits of diagnostic algorithms; and c) development of finite element models to accurately mimic breast phantoms to avoid repeated phantom experiments. The first would allow repeatable phantom trials in lieu of relying on volunteers. The second would enable more accurate assessment of errors and their impact on surface motion diagnostics. Equally, it would also allow assessment of whether improvements in sensing or actuation would make a clinical differences. The final, third element would further improve productivity by replacing phantom tests with models to generate “data”. The overall outcome is significantly enhanced development pathways.
In this thesis, mechanical properties of three different materials; agar, gelatine, and silicone used to emulate the mechanical behavior of real breast tissue are measured to assess their suitability for use in phantoms in systems assessing tissue mechanics for diagnostics. The stiffness ratio of adipose to tumor between the phantom materials and real human tissues were compared. Hyperelastic parameters of Neo-Hookean, Mooney Rivil, and Ogden models were obtained for the selected silicone material due to its appropriate mechanical properties, reliability, and repeatability. Finally, silicone based three homogenous phantoms of selected material were fabricated with different sizes of tumor.
Finite element models of breast shaped phantoms were developed using ABAQUS software. The geometry of the model was constructed with the same dimensions from fabricated phantoms. The mechanical properties were modeled by using the Neo-Hookean hyperelastic material model. Results showed good to strong correlation ranging from 0.7 to 1.0 in all cases with over 90% having a value over 0.9.Overall, the comparison of the DIET experimental data and the FE model data showed good agreement.
A single point laser Doppler vibrometer was used to validate the optical flow motion measuring algorithm used in DIET experimental data. Results show excellent validation with errors less than 6 % for healthy phantom, and errors less than 8 % for 10 mm and 20 mm inclusions. Overall results show the optical flow algorithm is validated with relatively small errors compared to a gold-standard, non-contact laser measurement.
Finally, because of the validation effectiveness and accuracy of finite element modeling compared to DIET experimental data. Six new phantoms were modeled with different tumor positions. This analysis assess the impact of tumor position on diagnosis of breast cancer using surface motions and basic elastography assumptions, which should further impact and encourage the development of DIET.
Overall, all 3 goals are accomplished. The results of this thesis provide means to dramatically speed up development of the DIET system. More generally, they provide significant results to enable elastographic technology development
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