22 research outputs found

    Adoption of Insulin Pumps and Continuous Glucose Monitors: Patient Perceptions of Utility and Usability

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    This thesis aims to capture patient perceptions of adoption and use of insulin pumps (IP) and continuous glucose monitors (CGM). The first two phases were dedicated to identify barriers and benefits of adoption of IP and CGM respectively. Four themes were identified in the insulin pump study: 1. the lack of value add to management, 2. the psychosocial impact, 3. requirement of a support structure during adoption, 4. need for behavioural readjustment for success. In the CGM phase, three themes were identified: 1. frustrations, 2. data promotes and proactivity, 3. cost/benefit analysis as a substantial barrier to adoption.In the third phase, a usability study of the five insulin pumps on the North American market was conducted. Ultimately, the Tandem pump caused the fewest use errors that could result in significant safety risk. Based on the results, recommendations to manufacturers and for tailoring diabetes training protocols were made.M.H.Sc

    Adoption of Insulin Pumps and Continuous Glucose Monitors: Patient Perceptions of Utility and Usability

    No full text
    This thesis aims to capture patient perceptions of adoption and use of insulin pumps (IP) and continuous glucose monitors (CGM). The first two phases were dedicated to identify barriers and benefits of adoption of IP and CGM respectively. Four themes were identified in the insulin pump study: 1. the lack of value add to management, 2. the psychosocial impact, 3. requirement of a support structure during adoption, 4. need for behavioural readjustment for success. In the CGM phase, three themes were identified: 1. frustrations, 2. data promotes and proactivity, 3. cost/benefit analysis as a substantial barrier to adoption.In the third phase, a usability study of the five insulin pumps on the North American market was conducted. Ultimately, the Tandem pump caused the fewest use errors that could result in significant safety risk. Based on the results, recommendations to manufacturers and for tailoring diabetes training protocols were made.M.H.Sc

    Bilateral and unilateral arm training improve motor function through differing neuroplastic mechanisms: a single-blinded randomized controlled trial

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    BACKGROUND AND PURPOSE: This randomized controlled trial tests the efficacy of bilateral arm training with rhythmic auditory cueing (BATRAC) versus dose-matched therapeutic exercises (DMTEs) on upper-extremity (UE) function in stroke survivors and uses functional magnetic resonance imaging (fMRI) to examine effects on cortical reorganization. METHODS: A total of 111 adults with chronic UE paresis were randomized to 6 weeks (3×/week) of BATRAC or DMTE. Primary end points of UE assessments of Fugl-Meyer UE Test (FM) and modified Wolf Motor Function Test Time (WT) were performed 6 weeks prior to and at baseline, after training, and 4 months later. Pretraining and posttraining, fMRI for UE movement was evaluated in 17 BATRAC and 21 DMTE participants. RESULTS: The improvements in UE function (BATRAC: FM Δ = 1.1 + 0.5, P = .03; WT Δ = -2.6 + 0.8, P < .00; DMTE: FM Δ = 1.9 + 0.4, P < .00; WT Δ = -1.6 + 0.7; P = .04) were comparable between groups and retained after 4 months. Satisfaction was higher after BATRAC than DMTE (P = .003). BATRAC led to significantly higher increase in activation in ipsilesional precentral, anterior cingulate and postcentral gyri, and supplementary motor area and contralesional superior frontal gyrus (P < .05). Activation change in the latter was correlated with improvement in the WMFT (P = .01). CONCLUSIONS: BATRAC is not superior to DMTE, but both rehabilitation programs durably improve motor function for individuals with chronic UE hemiparesis and with varied deficit severity. Adaptations in brain activation are greater after BATRAC than DMTE, suggesting that given similar benefits to motor function, these therapies operate through different mechanisms

    Preparation of self-healing acrylic latex coatings using novel oil-filled ethyl cellulose microcapsules

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    Novel oil-filled microcapsules were prepared by introducing a phase separation method using ethyl cellulose as a shell-forming containing rapeseed oil. The prepared oil-filled microcapsules were evaluated by optical microscopy, scanning electron microscopy and particle size analysis. Results showed that spherical microcapsules with a diameter of 10 to 45 μm and a rough porous shell were obtained. Carboxylated styrene/butadiene copolymer latex films containing various levels of these microcapsules were subjected to various levels of pre-elongation and their tensile properties were examined. The addition of oil-filled microcapsules resulted in a significant improvement in the modulus, strain-to-break, and toughness of the films. The self-healing mechanism of latex films was examined through the colorimetric measurements of the release of dye-containing following the pre-elongation of the samples. These measurements confirmed that pre-elongation of samples resulted in the release of oil within the latex films, hence plasticizing the surrounding polymeric network and partly restoring the mechanical properties of the pre-elongated films

    Differential regulatory roles of crustacean predators in a sub-Arctic, soft-sediment system

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    The role of predation in structuring soft-sediment communities varies as a function of the number and composition of predators that co-occur in a given habitat. In Bonne Bay, Newfoundland, contrasting abundances or predators in different areas of the bay may contribute to different regulatory roles of predators on infauna. To test this hypothesis, results from a field exclusion experiment were compared with 5 laboratory experiments that measured the individual effects of the main crustacean predators of the bay: snow crab, rock crab, and toad crab. In the field experiment, the exclusion of predators generated clear differences in infaunal composition, and 2 species (the polychaete Pholoe tecta and the clam Macoma calcarea) dominated exclusion treatments. Predator exclusion also resulted in a significant increase in density, but only a modest increase in infaunal diversity. In the laboratory, fresh, undisturbed sediment cores were paired with similar cores, protected by mesh and exposed to each crab species in order to test for their potential effects on infaunal communities. Results indicate that snow crab and rock crab have clear effects on species composition and, as was the case with the field experiment, the infaunal species P. tecta and M calcarea dominated exclusion treatments for both predatory crabs. These predators also reduced total infaunal density, but only rock crab significantly reduced species richness. In contrast, toad crab effects were not significant. Given that snow crab and rock crab are both targeted by commercial fisheries in Atlantic Canada, our results suggest that crab fishery removal may have multiple indirect effects on infaunal communities.PT: J; CR: AGARDY T, 2000, ICES J MAR SCI, V57, P761 AMBROSE WG, 1984, MAR ECOL-PROG SER, V17, P109 ARMONIES W, 1992, MAR ECOL-PROG SER, V83, P197 BARBEAU MA, 1994, J EXP MAR BIOL ECOL, V180, P103 BARBEAU MA, 1994, J EXP MAR BIOL ECOL, V182, P27 BEAL BF, 2001, J EXP MAR BIOL ECOL, V264, P133 BLACKBURN TH, 1996, MAR ECOL-PROG SER, V141, P283 BRETHES JCF, 1984, CRUSTACEANA, V47, P235 BUNDY A, 2001, CAN J FISH AQUAT SCI, V58, P1153 COLBOURNE EB, 2002, 0234 NAFO SCR COMEAU M, 1998, CAN J FISH AQUAT SCI, V55, P262 COMMITO JA, 1985, MAR ECOL-PROG SER, V26, P289 COMMITO JA, 1995, ECOL MONOGR, V65, P1 DAVIS JLD, 2003, J EXP MAR BIOL ECOL, V293, P23 DRUMMONDDAVIS NC, 1982, CAN J FISH AQUAT SCI, V39, P636 DUTIL JD, 1997, J EXP MAR BIOL ECOL, V212, P81 ELNER RW, 1979, J FISH RES BOARD CAN, V36, P537 ENNIS GP, 1990, CAN J FISH AQUAT SCI, V47, P2242 FAUCHALD K, 1979, OCEANOGR MAR BIOL AN, V17, P193 FAUCHALD P, 2002, MAR ECOL-PROG SER, V231, P279 FERNANDES TF, 1999, J EXP MAR BIOL ECOL, V241, P137 FINELLI CM, 2000, ECOLOGY, V81, P784 FOLK RL, 1980, PETROLOGY SEDIMENTAR GABRIEL KR, 1971, BIOMETRIKA, V58, P453 GILBERT D, 1993, CAN DATA REP HYDROGR, V122, P1 GILBET D, 1996, CAN DATA REP HYDROGR, V143, P1 GREEN RH, 1979, SAMPLING DESIGN STAT GUNTHER CP, 1992, NETH J SEA RES, V30, P45 HALL SJ, 1990, AM NAT, V136, P657 HILBORN R, 1997, MONOGRAPHS POPULATIO, V28 HINES AH, 1990, MAR ECOL-PROG SER, V67, P105 HOOPER RG, 1986, CRUSTACEANA, V50, P257 HUDON C, 1989, MAR ECOL-PROG SER, V52, P155 HULBERG LW, 1980, CAN J FISH AQUAT SCI, V37, P1130 KNEIB RT, 1991, AM ZOOL, V31, P874 LEFEBVRE L, 1991, CAN J FISH AQUAT SCI, V48, P1167 LENIHAN HS, 2001, MARINE COMMUNITY ECO, P253 LOVRICH GA, 1997, J EXP MAR BIOL ECOL, V211, P225 MALLET P, 1996, 9698 DFO MOODY KE, 1993, J EXP MAR BIOL ECOL, V168, P111 NADEAU M, 1998, J SHELLFISH RES, V17, P905 NORKKO A, 2001, MAR ECOL-PROG SER, V212, P131 OLAFSSON EB, 1994, OCEANOGR MAR BIOL, V32, P65 ORENSANZ JML, 1998, REV FISH BIOL FISHER, V8, P117 PACE ML, 2001, SCALING RELATIONS EX, P157 PALOMO G, 2003, J EXP MAR BIOL ECOL, V290, P211 PAUL AJ, 2001, P CRAB 2001 S AL SEA PETERSON CH, 1979, ECOLOGICAL PROCESSES, P233 POSEY MH, 1991, ECOLOGY, V72, P2155 QUIJON PA, IN PRESS OECOLOGIA RAMEY PA, 2003, MAR ECOL-PROG SER, V262, P215 REAL LA, 1979, ECOLOGY, V60, P481 ROBICHAUD DA, 1991, FISH B-NOAA, V89, P669 ROUSE GW, 2001, POLYCHAETES SAINTEMARIE B, 1995, CAN J FISH AQUAT SCI, V52, P903 SAINTEMARIE B, 1997, CAN J FISH AQUAT SCI, V54, P496 SALIERNO JD, 2003, J EXP MAR BIOL ECOL, V287, P249 SCARRATT DJ, 1972, J FISH RES BOARD CAN, V29, P161 SCHNEIDER DC, 1997, J EXP MAR BIOL ECOL, V216, P129 SEITZ RD, 2001, ECOLOGY, V82, P2435 SEITZ RD, 2001, ICES J MAR SCI, V58, P689 SIH A, 1998, TRENDS ECOL EVOL, V13, P350 SOKAL RR, 1994, BIOMETRY PRINCIPLES SQUIRES HJ, 1996, CAN MANUSCR FISH AQU, V2359 SQUIRES HJ, 2003, J NORTHW ATL FISH SC, V32, P2738 STEELE MA, 1996, J EXP MAR BIOL ECOL, V198, P249 STEHLIK LL, 1993, J CRUSTACEAN BIOL, V13, P723 STEPHEN DW, 1986, FORAGING THEORY STEWARTOATEN A, 2001, ECOL MONOGR, V71, P305 THOMPSON RJ, 1989, P INT S KING TANN CR, P283 THRUSH SE, 1999, AUST J ECOL, V24, P344 THRUSH SF, 1986, MAR ECOL-PROG SER, V30, P221 TREMBLAY MJ, 1994, CAN TECH REP FISH AQ, V2021 TRUEBLOOD DD, 1994, LIMNOL OCEANOGR, V39, P1440 UNDERWOOD AJ, 1996, 34 IOC UNESCO WEISSBERGER EJ, 1999, OECOLOGIA, V119, P461 WIECZOREK SK, 1995, J CRUSTACEAN BIOL, V15, P236 WILSON WH, 1986, MAR ECOL-PROG SER, V32, P35 WILSON WH, 1991, ANNU REV ECOL SYST, V21, P221 WORM B, 2003, ECOLOGY, V84, P162 YAMADA SB, 1996, J EXP MAR BIOL ECOL, V204, P59 ZAJAC RN, 1998, HYDROBIOLOGIA, V375, P227; NR: 82; TC: 4; J9: MAR ECOL-PROGR SER; PG: 13; GA: 899ZSSource type: Electronic(1

    Interdisciplinary Research in Rehabilitation and Traumatic Brain Injury : New Theoretical and Clinical Perspectives

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    Message from the Scientific Directors ; Introduction ; SECTION ONE : Moderate to severe traumatic brain injury PART I : Current state of knowledge - 1. Visual information processing in adults with traumatic brain injury, by Julie Lachapelle, Alain Ptito and Michelle McKerral. 2. The long-term impact of traumatic brain injury on the family, by Hélène Lefebvre, Diane Pelchat, Isabelle Gélinas, Bernard Michallet and Marie-Josée Levert ; PART II : Intervention - 1. Psychoanalytic psychotherapy following traumatic brain injury: A clinical case, by Jean R. Gagnon. 2. Traumatic brain injury and psychoactive substance abuse, by Monique Désilets, Hélène Lefebvre and Pauline Morissette. 3. Benign paroxysmal positional vertigo and traumatic brain injury: Specific evaluation and treatment, by Alain Godbout ; PART III : Contemporary perspectives - 1. The need for clinical practice guidelines in cognitive rehabilitation by Claude Paquette. 2. Clinicians, managers, and researchers: Joining forces to measure quality in rehabilitation services by Bonnie Swaine, Carolina Bottari, François Crépeau, Louise Demers, Monique Désilets, Elisabeth Dutil and Felicia Guarna. SECTION TWO Mild traumatic brain injury ; PART I : Current state of knowledge - 1. Identifying the sequelae of mild traumatic brain injury in children by Isabelle Gagnon, Robert Forget, Bonnie Swaine and Debbie Friedman. 2. Premorbidity and mild traumatic brain injury in adults, by Pierre Nolin, Johanne Bernier, Jennifer Mawn, Nathalie Boutin and Myriam Lanctôt.PART II : Intervention - 1. Intervention based on the multifactorial nature of MTBI, by Fanny Guérin, Aysha Dominique, Geneviève Léveillée, Stephan Kennepohl, Wormser Honoré, Nicole Brière and Michelle McKerral ; 2. Psychological intervention after mild traumatic brain injury: The use of resilience as a conceptual framework, by Frédéric Banville and Laurence Majaron ; Acknowledgements ; List of Institutions ; List of AbbreviationsThe aim of the Centre of Interdisciplinary Research in Rehabilitation of the Greater Montreal (CRIR) is to develop and refine, through its research activities, the scientific basis and knowledge required to guide effective and efficient rehabilitation interventions. The inverse is equally true, since, from issues encountered in the rehabilitation institutions, clinical practice guides the direction of scientific activities. Other goals of the CRIR are to strengthen partnerships between the universities and the clinical community, to build a succession of future researchers through the graduate study programs and scientific activities it organizes, and to develop a research culture in the rehabilitation institutions. When the first volume of the Publications du CRIR was launched just over a year ago, the Publishing Committee made a commitment to publish a second volume on the theme of traumatic brain injury (TBI). This issue currently provides very fertile ground for research and reflection among the members of our research centre. Moreover, we must not forget that this type of trauma causes high morbidity in Canada and Quebec. Progress in advanced medical technologies and the speed of emergency response have raised the life expectancies of these individuals, and have clearly made a significant impact on them and their families in the short, medium and long term. One year later, this second volume is an indicator of our efforts to respond, as well as possible, to the needs of those affected by TBI and their families. This volume is intended to disseminate the research and clinical studies on TBI that have been conducted under the auspices of the CRIR. Throughout the writing of this book, our hope was that it would bring together the interests of the diverse health care professional in the rehabilitation community, including the researchers and their students, all those who care for individuals who have sustained a TBI, the managers of the rehabilitation institutions, and the trauma victims themselves, along with their families.The publication of this book was supported by a grant from the Comité directeur de la recherche en traumatologie (Association des établissements de réadaptation en déficience physique du Québec, Association québécoise d’établissements de santé et de services sociaux, Société de l’assurance automobile du Québec — AERDPQ-AQESSS-SAAQ

    Recherche interdisciplinaire en réadaptation et traumatisme craniocérébral : Nouvelles perspectives théoriques et cliniques

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    Mot de la direction scientifique ; Introduction ; SECTION UN : Le TCC modéré à sévère PARTIE I : État des connaissances - 1. Étude du traitement de l’information visuelle chez l’adulte ayant subi un TCC par Julie Lachapelle, Alain Ptito et Michelle McKerral. 2. L’impact à long terme du TCC sur les proches, par Hélène Lefebvre, Diane Pelchat, Isabelle Gélinas, Bernard Michallet, et Marie-Josée Levert ; PARTIE II : Intervention - 1. La psychothérapie psychanalytique à la suite d’un TCC : présentation d’un cas clinique, par Jean R. Gagnon. 2. Le TCC et l’abus de substances psychoactives, par Monique Désilets, Hélène Lefebvre et Pauline Morissette. 3. Vertige paroxystique positionnel bénin et TCC : évaluation et traitement spécifiques, par Alain Godbout ; PARTIE III : Perspectives contemporaines - 1. Pour un guide pratique clinique en réadaptation cognitive par Claude Paquette. 2. Les intervenants, les gestionnaires et les chercheurs : ensemble pour une mesure de la qualité des soins et services en réadaptation, par Bonnie R. Swaine, Carolina Bottari, François Crépeau, Louise Demers, Monique Désilets, Elisabeth Dutil et Felicia Guarna. SECTION DEUX : Le TCC léger PARTIE I : État des connaissances - 1. Identification de séquelles à la suite d’un TCCL chez l’enfant par Isabelle Gagnon, Robert Forget, Bonnie R. Swaine et Debbie Friedman. 2. Prémorbidité et TCCL chez l’adulte par Pierre Nolin, Johanne Bernier, Jennifer Mawn, Nathalie Boutin, Myriam Lanctôt ; PARTIE II : Intervention - 1. Intervenir sur la nature multifactorielle du TCCL par Fanny Guérin, Aysha Dominique, Geneviève Léveillée, Stephan Kennepohl, Wormser Honoré, Nicole Brière et Michelle McKerral 2. Intervention psychologique de réadaptation après un TCCL : une approche utilisant la résilience en tant que cadre conceptuel, par Frédéric Banville et Laurence Majaron ; Remerciements ; Coordonnées des établissements ; GlossaireLe Centre de recherche interdisciplinaire en réadaptation du Montréal métropolitain (CRIR) a pour objectif de développer et de préciser par la recherche, qu’elle soit de nature fondamentale ou appliquée, qu’elle se situe dans un paradigme positiviste ou constructiviste, les bases scientifiques et les connaissances nécessaires pour guider des interventions de réadaptation efficaces et efficientes. L’inverse est également vrai puisque les pratiques cliniques orientent, à travers les questions qui se posent au sein des programmes et des équipes, les activités scientifiques et de recherche. Le CRIR a également pour objectif de renforcer le partenariat entre les universités et les milieux cliniques, de former par les programmes d’études supérieures et par les activités scientifiques qu’il organise, la relève des futurs chercheurs et le développement d’une culture de recherche dans les établissements de réadaptation. Lors du lancement du premier volume des Publications du CRIR, il y a un peu plus d’un an, le comité des publications a pris l’engagement d’en publier un second sur le thème des traumatismes craniocérébraux (TCC). Cette problématique constitue un terrain de recherche et de réflexion actuellement très fertile pour les membres de notre centre de recherche. De plus, il ne faut pas oublier que ces traumatismes constituent une source importante de morbidité au Canada et au Québec. L’avancement des technologies médicales de pointe et la rapidité avec laquelle les soins d’urgence sont dispensés augmentent l’espérance de vie de ces personnes, ce qui produit évidemment un impact considérable sur la personne et ses proches à court, moyen et long terme. Un an plus tard, ce second volume est un indicateur de nos activités visant à répondre le plus adéquatement possible aux besoins des personnes ayant subi un TCC et de leur entourage. Ce volume vise à faire connaître les recherches et réflexions cliniques concernant les TCC menées dans le contexte des activités du CRIR. Tout au long de son élaboration, notre souhait était qu’il rejoigne les intérêts des divers acteurs de la réadaptation, qu’il s’agisse des chercheurs et de leurs étudiants, des intervenants auprès des personnes ayant subi un TCC, des gestionnaires des établissements de réadaptation ou des personnes traumatisées elles-mêmes et leurs proches

    Development of surface replacement prostheses for the proximal interphalangeal and metacarpo phalangeal joints

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    There were two main aims of the project. A surface replacement prosthesis was previously designed at the University of Durham for the metacarpo-phalangeal joint (MCPJ). Tools were required to assess the joint prosthesis pre-operatively and postoperatively. The areas of assessment which the author was involved in were joint stiffness and a self-assessment questionnaire. The Durham arthrograph had previously been used for many clinical trials to assess joint stiffness objectively. However, the computer system was not portable. Hence a new computer system was developed, in Lab VIEW, for a lap-top computer. Ten normal individuals were assessed to validate the system. A questionnaire was also developed for patients to self-assess the performance of their joints. The questionnaire assessed parameters such as range of movement, hand strength, stiffness and pain on visual analogue scales. The difficulty in performing activities of daily living were assessed on simple descriptive scales. The second part of the project was to develop a surface replacement prosthesis for the proximal interphalangeal joint (PIPJ). Since there was inadequate information in the literature on the architecture of the PEPJ bearing surfaces and phalangeal bone shafts, a detailed study was performed on the bones from 83 PIPJs. Proximal and middle phalangeal bones were dissected, modelled in bone cement, sectioned and shadowgraphed. The shadowgraphs were measured and models of the proximal phalangeal heads were produced. These models were then used to design four PIPJ surface replacement prostheses over a range of sizes which covered 97.6% of the sample population of PIPJs. It was proposed that the MCPJ and PIPJ prostheses would be made entirely from cross-linked polyethylene (XLPE). Hence wear tests on pin-on-plate apparatuses were carried out to investigate the wear characteristics of XLPE-on-XLPE compared with other biomaterial combinations. The wear of XLPE-on-XLPE was comparable with UHMWPE-on-stainless steel. XLPE-on-stainless steel wore 10 times faster than XLPE-on-XLPE, and UHMWPE-on-UHMWPE wore 100 times faster than XLPE-on- XLPE. Hence it was concluded that all XLPE joint prostheses were feasible as far as the wear considerations were concerned
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