14 research outputs found
Effective Foreign Aid, Economic Integration and Subsidiarity: Lessons from Europe
No full textThe paper shows that the question that is relevant for the debate on the efficacy of development assistance is not so much as an issue of how much, but rather for what. In view of the growing awareness of ODA’s inefficiency in achieving intended aims, this paper proposes an alternative approach to development assistance policies – economic integration and subsidiarity provides the conditions necessary for ODA to produce higher rates of economic growth on a sustainable basis. Europe is an excellent case in point, in this context. Europe has in the last decades experienced a number of success stories in moving out of poverty and onto sustainable economic growth. The secret of success has been the push towards economic integration, and the adoption of economic reforms at the local, national, and regional level conducive to economic growth. The recipient countries of development assistance have much to learn from the European experience.foreign aid, economic integration, subsidiarity
sj-pdf-3-tmj-10.1177_03008916231157837 – Supplemental material for Breast implant associated anaplastic large cell lymphoma: Evidence for an efficient diagnostic workup
No full textSupplemental material, sj-pdf-3-tmj-10.1177_03008916231157837 for Breast implant associated anaplastic large cell lymphoma: Evidence for an efficient diagnostic workup by Laura Vittoria, Laura Sala, Valeria Summo, Iolanda Capone, Elena Conca, Martina Toma, Joseph Ottolenghi, Francesca Testa, Umberto Cortinovis, Biagio Paolini, Antonello Cabras, Antonella Aiello and Fabio Bozzi in Tumori Journal</p
sj-pdf-5-tmj-10.1177_03008916231157837 – Supplemental material for Breast implant associated anaplastic large cell lymphoma: Evidence for an efficient diagnostic workup
No full textSupplemental material, sj-pdf-5-tmj-10.1177_03008916231157837 for Breast implant associated anaplastic large cell lymphoma: Evidence for an efficient diagnostic workup by Laura Vittoria, Laura Sala, Valeria Summo, Iolanda Capone, Elena Conca, Martina Toma, Joseph Ottolenghi, Francesca Testa, Umberto Cortinovis, Biagio Paolini, Antonello Cabras, Antonella Aiello and Fabio Bozzi in Tumori Journal</p
sj-pdf-4-tmj-10.1177_03008916231157837 – Supplemental material for Breast implant associated anaplastic large cell lymphoma: Evidence for an efficient diagnostic workup
No full textSupplemental material, sj-pdf-4-tmj-10.1177_03008916231157837 for Breast implant associated anaplastic large cell lymphoma: Evidence for an efficient diagnostic workup by Laura Vittoria, Laura Sala, Valeria Summo, Iolanda Capone, Elena Conca, Martina Toma, Joseph Ottolenghi, Francesca Testa, Umberto Cortinovis, Biagio Paolini, Antonello Cabras, Antonella Aiello and Fabio Bozzi in Tumori Journal</p
sj-pdf-1-tmj-10.1177_03008916231157837 – Supplemental material for Breast implant associated anaplastic large cell lymphoma: Evidence for an efficient diagnostic workup
No full textSupplemental material, sj-pdf-1-tmj-10.1177_03008916231157837 for Breast implant associated anaplastic large cell lymphoma: Evidence for an efficient diagnostic workup by Laura Vittoria, Laura Sala, Valeria Summo, Iolanda Capone, Elena Conca, Martina Toma, Joseph Ottolenghi, Francesca Testa, Umberto Cortinovis, Biagio Paolini, Antonello Cabras, Antonella Aiello and Fabio Bozzi in Tumori Journal</p
sj-pdf-2-tmj-10.1177_03008916231157837 – Supplemental material for Breast implant associated anaplastic large cell lymphoma: Evidence for an efficient diagnostic workup
No full textSupplemental material, sj-pdf-2-tmj-10.1177_03008916231157837 for Breast implant associated anaplastic large cell lymphoma: Evidence for an efficient diagnostic workup by Laura Vittoria, Laura Sala, Valeria Summo, Iolanda Capone, Elena Conca, Martina Toma, Joseph Ottolenghi, Francesca Testa, Umberto Cortinovis, Biagio Paolini, Antonello Cabras, Antonella Aiello and Fabio Bozzi in Tumori Journal</p
sj-pdf-6-tmj-10.1177_03008916231157837 – Supplemental material for Breast implant associated anaplastic large cell lymphoma: Evidence for an efficient diagnostic workup
No full textSupplemental material, sj-pdf-6-tmj-10.1177_03008916231157837 for Breast implant associated anaplastic large cell lymphoma: Evidence for an efficient diagnostic workup by Laura Vittoria, Laura Sala, Valeria Summo, Iolanda Capone, Elena Conca, Martina Toma, Joseph Ottolenghi, Francesca Testa, Umberto Cortinovis, Biagio Paolini, Antonello Cabras, Antonella Aiello and Fabio Bozzi in Tumori Journal</p
Image_1_Management of BRCA Tumour Testing in an Integrated Molecular Tumour Board Multidisciplinary Model.pdf
No full textTumour testing of the BRCA1/2 genes is routinely performed in patients with different cancer histological subtypes. To accurately identify patients with tumour-detected germline pathogenic variants (PVs) is a relevant issue currently under investigation. This study aims at evaluating the performance of the tumour-to-germline diagnostic flowchart model defined at our Institutional Molecular Tumour Board (MTB). Results from tumour BRCA sequencing of 641 consecutive unselected cancer patients were discussed during weekly MTB meetings with the early involvement of clinical geneticists for appropriate referral to genetic counselling. The overall tumour detection rate of BRCA1/2 PVs was 8.7% (56/641), ranging from 24.4% (31/127) in high-grade ovarian cancer to 3.9% (12/304) in tumours not associated with germline BRCA1/2 PVs. Thirty-seven patients with PVs (66%) were evaluated by a clinical geneticist, and in 24 of them (64.9%), germline testing confirmed the presence of the PV in blood. Nine of these patients (37.5%) were not eligible for germline testing according to the criteria in use at our institution. Cascade testing was subsequently performed on 18 relatives. The tumour-to-germline diagnostic pipeline, developed in the framework of our institutional MTB, compared with guideline-based germline testing following genetic counselling, proved to be effective in identifying a higher number of germline BRCA PVs carriers.</p
Table_1_Management of BRCA Tumour Testing in an Integrated Molecular Tumour Board Multidisciplinary Model.xlsx
No full textTumour testing of the BRCA1/2 genes is routinely performed in patients with different cancer histological subtypes. To accurately identify patients with tumour-detected germline pathogenic variants (PVs) is a relevant issue currently under investigation. This study aims at evaluating the performance of the tumour-to-germline diagnostic flowchart model defined at our Institutional Molecular Tumour Board (MTB). Results from tumour BRCA sequencing of 641 consecutive unselected cancer patients were discussed during weekly MTB meetings with the early involvement of clinical geneticists for appropriate referral to genetic counselling. The overall tumour detection rate of BRCA1/2 PVs was 8.7% (56/641), ranging from 24.4% (31/127) in high-grade ovarian cancer to 3.9% (12/304) in tumours not associated with germline BRCA1/2 PVs. Thirty-seven patients with PVs (66%) were evaluated by a clinical geneticist, and in 24 of them (64.9%), germline testing confirmed the presence of the PV in blood. Nine of these patients (37.5%) were not eligible for germline testing according to the criteria in use at our institution. Cascade testing was subsequently performed on 18 relatives. The tumour-to-germline diagnostic pipeline, developed in the framework of our institutional MTB, compared with guideline-based germline testing following genetic counselling, proved to be effective in identifying a higher number of germline BRCA PVs carriers.</p
Table_2_Management of BRCA Tumour Testing in an Integrated Molecular Tumour Board Multidisciplinary Model.xlsx
No full textTumour testing of the BRCA1/2 genes is routinely performed in patients with different cancer histological subtypes. To accurately identify patients with tumour-detected germline pathogenic variants (PVs) is a relevant issue currently under investigation. This study aims at evaluating the performance of the tumour-to-germline diagnostic flowchart model defined at our Institutional Molecular Tumour Board (MTB). Results from tumour BRCA sequencing of 641 consecutive unselected cancer patients were discussed during weekly MTB meetings with the early involvement of clinical geneticists for appropriate referral to genetic counselling. The overall tumour detection rate of BRCA1/2 PVs was 8.7% (56/641), ranging from 24.4% (31/127) in high-grade ovarian cancer to 3.9% (12/304) in tumours not associated with germline BRCA1/2 PVs. Thirty-seven patients with PVs (66%) were evaluated by a clinical geneticist, and in 24 of them (64.9%), germline testing confirmed the presence of the PV in blood. Nine of these patients (37.5%) were not eligible for germline testing according to the criteria in use at our institution. Cascade testing was subsequently performed on 18 relatives. The tumour-to-germline diagnostic pipeline, developed in the framework of our institutional MTB, compared with guideline-based germline testing following genetic counselling, proved to be effective in identifying a higher number of germline BRCA PVs carriers.</p
