1,721,223 research outputs found
Sarcopenia and muscular modifications in disabling pathologies of the elderly from the physical and rehabilitation medicine: point of view
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Voltage stability constrained OPF market models considering N-1 contingency criteria
No full textThis paper proposes two novel techniques for including contingencies in OPF-based electricity market computations and for the estimation
of a “system-wide” available transfer capability (SATC). The OPF problem formulation includes voltage stability constraints and a loading
parameter in order to ensure a proper stability margin for the market solution. Two methods are proposed. The first technique is an iterative
approach and computes an SATC value based on an N − 1 contingency criterion for an initial optimal operating condition, to then solve an
OPF problem for the worst contingency case; this process is repeated until the changes in the SATC values are below a minimum threshold.
The second approach solves a reduced number of OPF problems associated with contingency cases according to a ranking based on a power
transfer sensitivity analysis of the transmission lines. Both methods are tested on a 6-bus system and on a realistic 129-bus Italian network
model considering supply and demand side bidding. Local marginal prices and nodal congestion prices resulting from the proposed solutions
as well as comparisons with results obtained by means of a standard OPF technique are also presented and discussed
Steam power plant repowering to provide black-start ancillary service and speed up power system restoration
No full textThe potential impact of new effervescent alendronate formulation on compliance and persistence in osteoporosis treatment.
No full textOsteoporotic fractures are a public health problem and their incidence and subsequent economic and social costs are expected to rise in the next future. Different drugs have been developed to reduce osteoporosis and the risk of osteoporotic fractures, and among them, antiresorptive agents, and in particular oral alendronate, are the most widely utilized. However, one of the most common problems with antiresorptive drugs is poor adherence to treatment, which is associated with a high fracture incidence and with an increase in hospitalization costs. One of the main reasons of poor adherence to these treatments is the occurrence of adverse events, mainly at gastrointestinal (GI) level, including dyspepsia, dysphagia, and esophageal ulcers. In light of these considerations the aim of this paper is to perform a literature review to show the pathophysiologic bases of GI alendronate-induced adverse events and how new bisphosphonate formulations like effervescent alendronate can improve compliance and persistence to treatment and decrease the fracture rate incidence in osteoporotic patient
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