1,720,965 research outputs found
Linfoma mammario maschile:difficoltà diagnostiche . case report
No full textLinfoma mammario maschile:difficoltà diagnostiche . case repor
planning chirurgico della paziente affetta da eteroplasia mammaria: utilizzo della FDG PET/TC
No full textplanning chirurgico della paziente affetta da eteroplasia mammaria: utilizzo della FDG PET/T
carcinoma della mammella maschile: definizione di un protocollo terapeutico
No full textcarcinoma della mammella maschile: definizione di un protocollo terapeutic
identificazione del linfonodo sentinella: efficacia e sicurezza del verde di indocianina comparato al radiocolle
No full textidentificazione del linfonodo sentinella: efficacia e sicurezza del verde di indocianina comparato al radiocoll
Breast cancer and gastrointestinal metastasis. A case report and review of the literature
No full textIntroduction: Invasive lobular cancer (ILC) is the second most common type of a heterogeneous group of different histological types of invasive breast carcinoma. Breast cancer can metastatize anywhere, the most common sites are bones, liver, lungs and brain. Gastrointestinal tract (GI) metastases observed in autopsy studies account for about 6% to 18% of the overall metastases from breast cancer. Objective: We describe a 54-year old woman with recurrent ILC in the contralateral breast. She underwent right mastectomy 16 years before. After symptomatic presentation a duodenal invasion was found and subjected to diagnostic scrutiny (FDG PET/CT, diagnostic CT, MR, EGDS). In particular, we analyse if FDG PET/CT is enough accurate in the restaging of the patient. A review of our database and of the literature of similar cases were made. Results: In this patient CT and RM were suspicious for a slow developing process of the duodenum but FDG PET/CT did not show pathological uptake in the affected duodenal tract. A highly intense focus was described in a cervical lymph node, that there isn't metastatic lesion, whereas the recurrent breast lesion had only slight increased glycolytic activity. CONCLUSION: Metastatic lobular carcinoma of the breast is a rare entity with a heterogeneous range of clinical presentations. Detection of eventual gastrointestinal metastases are complicated to assess. ILC has various scale of glycolytic activity both in the primary lesion as well in the metastatic foci. When the level of suspicion is high and there is no uptake of FDG, further investigations are necessary
Breast cancer and neoadjuvant chemotherapy: indications for and limits of breast-conserving surgery
No full textAIM: The aim of our study was to determine how many and what subtypes of breast cancer could be treated with breast-conserving surgery after NACT. Another outcome was to determine the applicability of MD Anderson Cancer Center nomogram to predict it. MATERIAL OF STUDY: We reviewed the histological examinations of 86 performed mastectomies according to the indications to BCS after NACT. For 73 cases, collected all the necessary data, we could use the nomogram available on the MDACC website to calculate the probability of BCS and pCR. RESULTS: In our experience the BCS rate would increase by 34,1%, from 3,7% to 3.,8%. Patients with Triple Negative and HER2+, ER- more than ER+, show higher rates of pCR and BCS. The MDACC nomogram predicts accurately the probability of pCR and BCS after NACT in HER2 negative cancers but not in HER2 positive ones treated with Trastuzumab. This suggests that a specific nomogram for HER2 positive carcinomas has to be developed. CONCLUSION: BCS after NACT is feasible and safe in terms of LRR, DFS and OS, if patients are properly studied and selected. Indication to BCS after NACT needs of a multidisciplinary assessment considering clinical staging, biological characteristics, the radiological response pattern and the expected concordance between imaging and histology
Male breast MRI: a review of different pathological conditions
No full text: The male breast is predisposed to be affected by many of the same pathological processes as the female breast is. The diagnosis of male breast pathologies is generally achievable when clinical evaluation is combined with standard breast imaging methods such as mammography and ultrasound. Magnetic resonance imaging is also a valuable tool in diagnosing the main pathologies affecting the male breast, especially for evaluating pre- and post-surgical treatments and follow-up. However, although this technique has been sufficiently regulated and adopted by many breast radiologists for female breast imaging, its application in the diagnosis of male breast pathologies remains limited to a few specialized centers. This article, based on a retrospective analysis of the experience of the University of Verona, explores various aspects of male breast diseases, including benign conditions such as gynecomastia and breast implant ruptures in transgender women as well as malignant entities such as male breast cancer. Emphasis is placed on the distinctive morphological features, enhancement patterns and kinetics observed in male breast lesions on dynamic contrast-enhanced MRI. This article provides a comprehensive overview of the application of MRI in male breast disease assessment, highlighting the potential role of MRI as a complementary tool to traditional breast imaging techniques
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