1,354,279 research outputs found

    A rare aggravation of severe mucositis post chemotherapy in a child with acute lymphoblastic leukemia

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    Oral mucositis is a debilitating manifestation in children undergoing chemotherapy and radiotherapy. Children with mucositis should be properly managed in order to prevent further exacerbation and adverse complications. We hereby present the first report of a severe chemotherapy-induced mucositis, plausibly aggravated by improper dental hygiene leading to shedding of the ventral part of the tongue in a child with pre-B acute lymphoblastic leukemia (ALL). The patient steadily and gradually recovered her oral maneuvers and ability to speak several months later. Her tongue underwent hypertrophy as a compensatory mechanism. We recommend that critical and regular assessment of the oral mucosa and proper dental care and oral hygiene be emphasized in all pediatric patients receiving chemotherapy. Families of affected children need to be educated about the benefits and modes of optimal oral hygiene for their children and the need to seek immediate care for mouth pain and or lesions. Optimal treatment for mucositis needs to be instituted without delay in this high risk pediatric population. Such a preventive and therapeutic approach may prevent associated life threatening oral and systemic complications, promote rapid and complete mucosal healing, alleviate pain and improve quality of life in children with cancer. © 2013 Inati A et al

    Inati vocabulary

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    This Inati vocabulary was written by Delia Panden, a native speaker of Inati who is also fluent in Kinaray-a, Tagalog, and English. The vocabulary was intended for use as an elementary school primer. Her husband, Carlito Panden, is a pastor at the Hamtic Bible Believing Church in Poblacion 4, Hamtic municipality, Antique province, Panay island, Philippines. The handwritten manuscript consists of 13 pages, and was photographed by Andrew Hsiu in September 2013. Transcription is highly inconsistent. Preliminary gloss translations from Kinaray-a to English, which are not entirely complete, have been kindly assisted by Josemari “Joma” Cordova of Vongchavalitkul University. Photographs of Delia Pandan's manuscripts that I took in September 2013 have also been uploaded

    Inati vocabulary

    No full text
    This Inati vocabulary was written by Delia Panden, a native speaker of Inati who is also fluent in Kinaray-a, Tagalog, and English. The vocabulary was intended for use as an elementary school primer. Her husband, Carlito Panden, is a pastor at the Hamtic Bible Believing Church in Poblacion 4, Hamtic municipality, Antique province, Panay island, Philippines. The handwritten manuscript consists of 13 pages, and was photographed by Andrew Hsiu in September 2013. Transcription is highly inconsistent. Preliminary gloss translations from Kinaray-a to English, which are not entirely complete, have been kindly assisted by Josemari “Joma” Cordova of Vongchavalitkul University. Photographs of Delia Pandan's manuscripts that I took in September 2013 have also been uploaded

    The role of liver iron in hepatitis C antiviral treatment

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    [No abstract available]Alexander J, 2007, LIVER INT, V27, P268, DOI 10.1111-j.1478-3231.2007.01449.x; Ancel D, 2009, EUR J GASTROEN HEPAT, V21, P726, DOI 10.1097-MEG.0b013e3283097699; Fujita N, 2007, J GASTROEN HEPATOL, V22, P1886, DOI 10.1111-j.1440-1746.2006.04759.x; HIRST C, 2002, COCHRANE DB SYST REV, V1, P3146; Inati A, 2005, BRIT J HAEMATOL, V130, P644, DOI 10.1111-j.1365-2141.2005.05645.x; Taher AT, 2009, ANN HEMATOL, V88, P1033, DOI 10.1007-s00277-009-0713-y11

    Iron in sickle-cell disease: What have we learned over the years?

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    Over the last four decades, monumental advances have been made in the understanding, assessment, and management of transfusion-dependent patients, which have translated into significant improvements in patient morbidity and mortality. Important lessons have been learned from extensive clinical experience of iron management in the thalassemias, but greater knowledge of key differences in the sickle-cell disease (SCD) population may impact on our approach to patient assessment and management. The unique pathophysiology of SCD is reflected in a distinct pattern of iron loading with minimal organ-specific injury. 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    Sickle cell disease: New insights into pathophysiology and treatment

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    [No abstract available]Adams RJ, 1998, NEW ENGL J MED, V339, P5, DOI 10.1056-NEJM199807023390102; Anthi A, 2007, AM J RESP CRIT CARE, V175, P1272, DOI 10.1164-rccm.200610-1498OC; Ballas SK, 2005, HEMATOL ONCOL CLIN N, V19, P785, DOI 10.1016-j.hoc.2005.07.008; Ballas Samir K, 2007, Hematology Am Soc Hematol Educ Program, P97; Bernaudin F, 2007, BLOOD, V110, P2749, DOI 10.1182-blood-2007-03-079665; Boyd JH, 2006, BLOOD, V108, P2923, DOI 10.1182-blood-2006-01-011072; Boyd JH, 2007, HAEMATOL-HEMATOL J, V92, P1115, DOI 10.3324-haematol.11213; Burnett AL, 2006, UROLOGY, V67, P1043, DOI 10.1016-j.urology.2005.11.045; CAO A, 1987, Blood Reviews, V1, P169, DOI 10.1016-0268-960X(87)90032-4; CHARACHE S, 1992, BLOOD, V79, P2555; CHARACHE S, 1995, NEW ENGL J MED, V332, P1317, DOI 10.1056-NEJM199505183322001; Chiang EY, 2005, HEMATOL ONCOL CLIN N, V19, P771, DOI 10.1016-j.hoc.2005.08.002; Cokic VP, 2003, J CLIN INVEST, V111, P231, DOI 10.1172-JCI200316672; DeSimone J, 2002, BLOOD, V99, P3905, DOI 10.1182-blood.V99.11.3905; Finnegan EM, 2007, AM J PHYSIOL-HEART C, V293, pH1038, DOI 10.1152-ajpheart.01054.2006; FRENETTE PS, 2007, CLIN INVESTIGATOR, V117, P850; Givens M, 2007, J EMERG MED, V32, P239, DOI 10.1016-j.jemermed.2006.07.022; Gladwin MT, 2003, CIRCULATION, V107, P271, DOI 10.1161-01.CIR.0000044943.12533.A8; Gladwin MT, 2004, NEW ENGL J MED, V350, P886, DOI 10.1056-NEJMoa035477; Gulbis B, 2005, BLOOD, V105, P2685, DOI 10.1182-blood-2004-07-2704; Halasa NB, 2007, CLIN INFECT DIS, V44, P1428, DOI 10.1086-516781; Hankins JS, 2005, BLOOD, V106, P2269, DOI 10.1182-Blood-2004-12-4973; Hankins JS, 2008, PEDIATR BLOOD CANCER, V50, P293, DOI 10.1002-pbc.21271; Haque AK, 2002, HUM PATHOL, V33, P1037, DOI 10.1053-hupa.2002.128059; Hoppe C, 2007, STROKE, V38, P2241, DOI 10.1161-STROKEAHA.107.483115; Inati A, 2007, INT J LAB HEMATOL, V29, P399, DOI 10.1111-j.1751-553X.2007.00964.x; INATI A, 2006, CLIN LAB HAEMATOL, V28, P2172; INGRAM VM, 1957, NATURE, V180, P326, DOI 10.1038-180326a0; Iyamu EW, 2005, BRIT J HAEMATOL, V131, P389, DOI 10.1111-j.1365-2141.2005.05772.x; KATO GJ, 2007, EHA; Kinney TR, 1999, BLOOD, V94, P1550; Kuypers Frans A, 2007, Hematology Am Soc Hematol Educ Program, P68; Loscalzo J, 2001, CIRC RES, V88, P756, DOI 10.1161-hh0801.089861; Machado RF, 2005, BRIT J HAEMATOL, V130, P445, DOI 10.1111-j.1365-2141.2005.05625.x; Miller ST, 2000, NEW ENGL J MED, V342, P83, DOI 10.1056-NEJM200001133420203; Miller ST, 2001, J PEDIATR-US, V139, P385, DOI 10.1067-mpd.2001.117580; Morris CR, 2005, JAMA-J AM MED ASSOC, V294, P81, DOI 10.1001-jama.294.1.81; Nolan VG, 2005, BLOOD, V106, P3264, DOI 10.1182-blood-2005-04-1594; Ohene-Frempong K, 1998, BLOOD, V91, P288; Panepinto JA, 2007, BRIT J HAEMATOL, V137, P479, DOI 10.1111-j.1365-2141.2007.06592.x; PAULING L, 1949, SCIENCE, V110, P543, DOI 10.1126-science.110.2865.543; PERRINE RP, 1978, ANN INTERN MED, V88, P1; PLATT OS, 1994, NEW ENGL J MED, V330, P1639, DOI 10.1056-NEJM199406093302303; PLATT OS, 1984, J CLIN INVEST, V74, P652, DOI 10.1172-JCI111464; Quinn CT, 2004, BLOOD, V103, P4023, DOI 10.1182-blood-2003-11-3758; Reiter CD, 2002, NAT MED, V8, P1383, DOI 10.1038-nm799; Saleh AW, 1999, ACTA HAEMATOL-BASEL, V102, P31, DOI 10.1159-000040964; Serjeant G R, 1995, Curr Opin Hematol, V2, P103; Steinberg MH, 1999, NEW ENGL J MED, V340, P1021; Steinberg MH, 2003, JAMA-J AM MED ASSOC, V289, P1645, DOI 10.1001-jama.289.13.1645; Stuart MJ, 2004, LANCET, V364, P1343, DOI 10.1016-S0140-6736(04)17192-4; Styles LA, 2000, BLOOD, V96, P3276; Tamouza R, 2007, HUM IMMUNOL, V68, P849, DOI 10.1016-j.humimm.2007.08.260; Telen Marilyn J, 2007, Hematology Am Soc Hematol Educ Program, P84; TELFER P, HAEMATOLOGICA, V92, P905; Vichinsky E, 2001, SEMIN HEMATOL, V38, P1, DOI 10.1016-S0037-1963(01)90053-8; Vichinsky EP, 1997, BLOOD, V89, P1787; Vichinsky EP, 2000, NEW ENGL J MED, V342, P1855, DOI 10.1056-NEJM200006223422502; Weinberg RS, 2005, BLOOD, V105, P1807, DOI 10.1182-blood-2004-02-0454; Zimmerman SA, 2007, BLOOD, V110, P1043, DOI 10.1182-blood-2006-11-05789346

    Inati (Hamtic) audio word list

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    <p>In September 2013, I recorded 2 dialects of Inati in the Philippines.</p> <ul> <li>An Ati settlement in Jordan, Guimaras. Turnoff to the right as one is approaching the Sibunag municipality gate from the harbor.</li> <li>Poblacion 4, Hamtic, Antique, Panay Island</li> </ul> <p>In Jordan, Guimaras, my informants reported that they had relatives in Barotac Viejo, Iloilo. The villagers are impoverished, and reported often skipping meals. Villagers there also make some woven handicrafts (basketry, etc.) for a living.<br> <br> In Hamtic, my Ati Informants were Delia Panden and Carlito Panden of Poblacion 4, Hamtic, Antique.<br> <br> Carlito Panden is a pastor at a local Protestant church that is very close to the town center, while Delia Panden is an elementary school teacher. They speak Inati, Kinaray-a, Tagalog, and English. Their church gets some funding from churches in South Korea too.<br> <br> The Panden couple also expressed interest in publishing their Inati vocabulary notes as a book.<br> <br> Carlito Panden also brought me to Tina Victory Church, which was located in Barangay Tina.<br> <br> Tina Victory Church<br> Agape Christian International Ministries, Inc.<br> In partnership with Book Sung Church, Daegu, Korea<br> Barangay Tina, Hamtic, Antique, Philippines</p>https://sites.google.com/site/msealangs/austronesian/inat

    Sickle cell disease: New insights into pathophysiology and treatment

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    Beta-thalassemia intermedia: an overview

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    Thalassemias are inherited anemias characterized by decreased or absent globin chain synthesis and by ineffective erythropoesis. They are classified according to the defective globin chain and to the clinical severity. Beta-thalassemias, which are prevalent in the Mediterranean region, have decreased or absent beta-globin chain synthesis whereas, in alpha-thalassemias, the alpha-chain is affected. Thalassemia major is a severe, transfusion-dependent anemia with significant morbidity and mortality. Thalassemia intermedia are a genetic variant of the beta-thalassemias, which incorporates a less severe anemia than thalassemia major with inefficient erythropoiesis as well as peripheral hemolysis. Leg ulcers, pulmonary arterial hypertension, extramedullary hematopoiesis, and thrombotic events are some of the complications that thalassemia intermedia patients face

    Inati (Guimaras) audio word list

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    <p>In September 2013, I recorded 2 dialects of Inati in the Philippines.</p> <ul> <li>An Ati settlement in Jordan, Guimaras. Turnoff to the right as one is approaching the Sibunag municipality gate from the harbor.</li> <li>Poblacion 4, Hamtic, Antique, Panay Island</li> </ul> <p>In Jordan, Guimaras, my informants reported that they had relatives in Barotac Viejo, Iloilo. The villagers are impoverished, and reported often skipping meals. Villagers there also make some woven handicrafts (basketry, etc.) for a living.</p>https://sites.google.com/site/msealangs/austronesian/inat
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