2,442 research outputs found
Southern Thailand: from conflict to negotiations?
No full textSummary: In this Analysis, University of Leeds professor Duncan McCargo argues that the recent Malaysian-backed Southern Thai peace initiative has now run into some serious problems. He argues that despite its various shortcomings the initiative is still worthy of support, since it has gained far more traction that any previous attempts to address the decade-long insurgency. Thailand needs to maintain focus on the southern conflict despite its current preoccupation with a national-level political crisis that threatens to topple the government of Yingluck Shinawatra.
Key findings
The conflict in Southern Thailand is one of Asia’s most serious insurgencies, with over 6,000 dead over the last 10 years.
The Malaysian government sponsored negotiations represents the best hope for reaching a political settlement and bringing peace to the region.
However, both sides need to show greater commitment to the negotiations, introducing new structures and procedures
Preservation assessment of the collections at the Oregon State Library, Salem, Oregon: October 6, 7 & 8, 2009
No full textReport -- Appendix A. Documentation Images -- Appendix B. Resources -- Appendix C. Recommended Books, Collection Policy Resources, Organizations for Reference & Vendors for Supplies -- Appendix D. Cost Estimates.prepared by Lisa Duncan, Art Conservator, LLC.Title from PDF title page (viewed on February 8, 2023).This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Includes bibliographical references.Mode of access: Internet from the Oregon Government Publications Collection.Text in English
Douglas and Duncan Wain
No full textPhotograph - Douglas and Duncan Wain with their mother in front of a house, Athabasca, Albert
SDF and GABA interact to regulate axophilic migration of GnRH neurons
No full textStromal derived growth factor (SDF-1) and gamma-aminobutyric acid (GABA) are two extracellular cues that regulate the rate of neuronal migration during development and may act synergistically. The molecular mechanisms of this interaction are still unclear. Gonadotropin releasing hormone-1 (GnRH) neurons are essential for vertebrate reproduction. During development, these neurons emerge from the nasal placode and migrate through the cribriform plate into the brain. Both SDF-1 and GABA have been shown to regulate the rate of GnRH neuronal migration by accelerating and slowing migration, respectively. As such, this system was used to explore the mechanism by which these molecules act to produce coordinated cell movement during development. In the present study, GABA and SDF-1 are shown to exert opposite effects on the speed of cell movement by activating depolarizing or hyperpolarizing signaling pathways, GABA via changes in chloride and SDF-1 via changes in potassium. GABA and SDF-1 were also found to act synergistically to promote linear rather than random movement. The simultaneous activation of these signaling pathways, therefore, results in tight control of cellular speed and improved directionality along the migratory pathway of GnRH neurons
Semiometrics: producing a compositional view of influence
No full textHigh-impact academic papers are not necessarily the most cited. For example, Einstein's 'Special Relativity' paper from 1905 received (and continues to receive) fewer citations from other papers than his 'Brownian Motion" paper of the same year, despite the former radically changing the course of an entire scientific discipline to a much greater extent. Similarly, 'impact' metrics using citation count alone are, it is argued, not adequate for determining the scientific influence of papers, authors or small groups of authors. Although valid, they remain controversial when used to determine influence of larger groups or journals. While the term 'impact' has become closely linked to a journal's citation-based Journal Impact Factor score, this thesis uses the term 'influence' to describe the wider effectiveness of research, combining citation and metadata analysis to allow richer calculations to be performed over large-scale document networks. As a result, more qualitative influence ratings can be determined and a broader outlook on scientific disciplines can be produced. These ratings are best applied using an ontology-based data source, allowing more efficient inference than under a traditional RDBMS system, and allowing easier integration between heterogeneous data sources. These metrics, termed 'Semantic Bibliometrics' or 'Semiometrics', can be applied at a variety of levels of granularity, allowing a compositional framework for impact and influence analysis. This thesis describes the process of data preparation, systems architecture, metric value and data integration for such a system, introducing novel approaches at all four stages, thereby creating a working semiometrics system for determining influence at different semantic levels of granularity
The Campbells: lordship, literature and liminality
No full textThe Campbells have the potential to offer much to the theme of literature and borders, given that the kindred’s astonishing political success in the late medieval and early modern period depended heavily upon the ability to negotiate multiple frontiers: between Highlands and Lowlands; between Gaelic Scotland and Ireland, and, especially after the Reformation, with England and the matter of Britain. This paper will explore the literary dimension to Campbell expansionism, from the Book of the Dean of Lismore in the earlier sixteenth century, to poetry addressed to dukes of Argyll in the earlier eighteenth century. Particular attention will be paid to the literary proclivities of the household of the Campbells of Glenorchy on either side of what appears to be a major watershed in 1550; and to the agenda of the Campbell protégé John Carswell, first post-Reformation bishop of the Isles, and author of the first printed book in Gaelic in either Scotland or Ireland, Foirm na n-Urrnuidheadh (‘The Form of Prayers’), published at Edinburgh in 1567
Semiometrics: Applying Ontologies across Large-Scale Digital Libraries
No full textAs large-scale digital libraries become more available and complete, not to mention more numerous, it is clear there is a need for services that can draw together and perform inference calculations on the metadata produced. However, the traditional Relational Database Management System (RDBMS) model, while efficiently constructed and optimised for many business structures, does not necessarily cope well with issues of concurrent data updates and retrieval at the scale of hundreds of thousands of papers. At the same time the growth of RDF and the increasing interest in Semantic Web technologies perhaps begins to present a viable alternative at a scalable, practical level. This paper considers a specific application of large-scale metadata analysis and conducts scalability tests using real-world data. It concludes that RDF technologies are both a scalable and performance-realistic alternative to traditional RDBMS approaches. It also shows that for relationship-based queries on large-scale metadata stores, RDF technologies can significantly out-perform traditional RDBMS approaches by allowing both retrieval and updating of data in a timely manner
Molecular mapping of the human major histocompatibility complex
No full text1. Pulsed field gel electrophoresis (PFGE) and cosmid walking have been used to establish a molecular map of the human major histocompatibility complex (MHC). Single copy hybridisation probes were isolated from clusters of cosmid clones, one containing the C2, factor B, C4 and 21-hydroxylase genes, and the other containing the genes for tumour necrosis factors (TNF) a and B. These probes and HLA class I and class II gene probes were hybridised to Southern blots of genomic DNA which had been digested with infrequently cutting restriction endonucleases and separated by PFGE. The data obtained allowed the construction of a long range genomic restriction map, indicating the MHC spans 3800 kb. This map orients the complement gene cluster with respect to DRA, the C2 gene being telomeric to the 21-hydroxylase B gene. In addition, the positions of the TNF genes were defined. The DRA and 21-hydroxylase B genes are separated by no greater than 390 kb, while the distance between the C2 and TNFA genes is 325 kb. The HLA-B locus lies about 250-300kb telomeric of the TNFB gene.2. The long range DNA organisation of the class II and class III regions in eight HLA homozygous cell lines has been analysed using PFGE. Comparison of the size of the BssHII restriction fragment observed for these cell lines and five individuals possessing one to three C4 genes, shows that the organisation of the C4 genes on each chromosome can be deduced from a single PFGE experiment. Outside of the C4 and 21-OHase loci the class III region shows a highly invariant structure, with no detectable differences in the amount of DNA present. Moreover the class III region is rich in CpG-islands, one of which has been characterised, and contains at least thirteen new genes. However, in the class II region, two differences between common haplotypes have been found. The DRw52-related haplotypes have the same DNA organisation. DR2 haplotypes possess 20-30 kb more DNA in the DRB region. DRw53 haplotypes have 100-130 kb more DNA than DRw52-related haplotypes in the region containing the DRB and DQA genes
Musical tributes to LUCIANO BERIO and LOU HARRISON new works by RICHARD LAVENDA and ANTHONY BRANDT Tuesday, October 28, 2003 8:00 p.m. Lillian H. Duncan Recital Hall
No full textPresented by SyzygyProgram: Korot / Luciano Berio (1925-2003) -- Yunggamurra / Betty Beath (b.1932) -- The Loneliness of A Lover's Arms / Christine McCombe (b. 1967) -- Dream With Me / Leonard Bernstein (1918-1990) -- Joy / Ricky Ian Gordon (b. 1956) -- Flight of Fancy / Richard Lavenda (b.1955) -- Round Top Trio / Anthony Brandt (b.1961) -- Concerto for Violin with Percussion Orchestra / Lou Harrison (1917-2003)
DEBORAH DUNHAM Double Bass DOCTORAL CHAMBER MUSIC RECITAL Thursday, September 28, 2006 8:00 p.m. Lillian H. Duncan Recital Hall
No full textProgram: L'enfants Prodigues: Azael's Aria / Claude Debussy (1862-1918) -- Weihnachts-Oratorium: Schliesse, mein Herze / Johann Sebastian Bach (1685-1750) -- Morning Star: This is not a song / Ricky Ian Gordon (b. 1956) -- I Capuleti e I Montecchi: O! Quante Volte / Vincenzo Bellini -- Kennst du das Land / Hugo Wolf (1860-1903) -- Faust: Salut, demeure chaste et pure / Charles Gounod (1818-1893).This recital is given in partial fulfillment of the requirements for Doctor of Musical Arts degree
- …
