1,721,603 research outputs found
Il complesso cammino delle agroenergie verso la sostenibilità. Quale ruolo per le comunità energetiche rinnovabili?
Full text linkL’articolo cerca di definire il ruolo che le agroenergie rivestono nella strategia energetica dell’Unione europea – così come delineata nel Green Deal e aggiornata nel contesto del Piano
RePowerEU – e, a cascata, nell’ordinamento giuridico italiano, sottolineando l’esigenza di assicurarne la sostenibilità, chiave di lettura per ricostruire il delicato rapporto tra attività di produzione agricola e attività di produzione energetica. Le misure gradualmente adottate a livello europeo e nazionale per avanzare nel complesso cammino verso la sostenibilità
delle agroenergie dimostrano l’acquisita consapevolezza dell’urgenza di investire non solo sulla sostenibilità ambientale, bensì anche su quella economica e sociale e, in particolare, sulla sostenibilità (sociale) alimentare delle agroenergie. In questa prospettiva, un significativo
contributo sembra pervenire dalle comunità energetiche rinnovabili (CER), modelli organizzativi innovativi che offrono interessanti opportunità anche per l’imprenditore agricolo. In particolare, analizzando il ruolo che l’impresa agricola può svolgere all’interno di una CER e, parallelamente, il contributo che queste strutture possono apportare al processo di affermazione della sostenibilità delle agroenergie, emergono chiaramente le potenzialità
delle comunità agroenergetiche per il processo di transizione energetica ed ecologica in atto
"Trattamento della sindrome compressiva recidivante del nervo mediano al polso mediante wrapping con vena autologa"
No full textTrattamento della sindrome compressiva recidivante del nervo mediano al polso mediante wrapping con vena autolog
The role of menin inhibitors in acute myeloid leukemia
No full textPurpose of reviewAcute myeloid leukemia (AML) characterized by NPM1 mutations or KMT2A rearrangements depends on abnormal epigenetic programs mediated by menin, a critical scaffold protein for sustaining the expression of oncogenic HOX/MEIS1 genes. Therefore, menin inhibitors have become a promising class of AML treatments.Recent findingsEarly-phase trials have shown that agents such as revumenib, ziftomenib, bleximenib, and enzomenib are active, particularly in relapsed/refractory disease, with 23-48% of patients achieving composite complete remission. However, the durability of single-agent treatment remains limited, and resistance mechanisms, such as MEN1 mutations or transcriptional reprogramming, have been identified. Consequently, combination approaches involving venetoclax, hypomethylating agents, or chemotherapy are being investigated to improve response depth and duration. Recent SAVE, KOMET-007, and cAMeLot-2 trials have demonstrated high overall response rates (68%-100%) and encouraging MRD-negative complete remissions when combining menin inhibitors with venetoclax-based regimens. This has been observed even in patients who have previously received venetoclax. Combinations with intensive chemotherapy (e.g., 7 + 3) in the frontline setting have also yielded high CRc rates (up to 94% in NPM1-mutated AML) without exacerbating toxicity.SummaryThese findings justify the integration of menin inhibitors into the AML therapeutic landscape, and support ongoing randomized trials to confirm their benefit in both frontline and relapse or refractory settings
Clinical differences between treated and not treated hypogonadal men; results from the SIAMO-NOI Study. Rastrelli G., Balercia G., Calogero A., Isidori A., et al. 38° Congresso Nazionale SIE, Taormina, 27-30 Maggio 2015, P019
No full textCluster dynamical mean-field methods for d-wave superconductors: Role of geometry
No full textWe compare the accuracy of two cluster extensions of dynamical mean-field theory in describing d-wave superconductors, using as a reference model a saddle-point t-J model which can be solved exactly in the thermodynamic limit and at the same time reasonably describes the properties of high-temperature superconductors. The two methods are cellular dynamical mean-field theory, which is based on a real-space perspective, and dynamical cluster approximation, which enforces a momentum-space picture by imposing periodic boundary conditions on the cluster, as opposed to the open boundary conditions of the first method. We consider the scaling of the methods for large cluster size, but we also focus on the behavior for small clusters, such as those accessible by means of present techniques, with particular emphasis on the geometrical structure, which is definitely a relevant issue in small clusters. RI Capone, Massimo/A-7762-200
Rotationally invariant slave bosons for strongly correlated superconductors
No full textWe extend the rotationally invariant formulation of the slave-boson method to superconducting states. This generalization, building on the recent work by Lechermann et al. [Phys. Rev. B 76, 155102 (2007)], allows to study superconductivity in strongly correlated systems. We apply the formalism to a specific case of strongly correlated superconductivity, as that found in a multiorbital Hubbard model for alkali-doped fullerides, where the superconducting pairing has phonic origin, yet it has been shown to be favored by strong correlation owing to the symmetry of the interaction. The method allows to treat on the same footing the strong correlation effects and the interorbital interactions driving superconductivity, and to capture the physics of strongly correlated superconductivity, in which the proximity to a Mott transition favors the superconducting phenomenon. RI Capone, Massimo/A-7762-200
Vibrazioni meccaniche nel trattamento delle lesioni dei nervi periferici: risultati definitivi nel trattamento delle lesioni postraumatiche del plesso brachiale e delle lesioni radicolari
No full textVibrazioni meccaniche nel trattamento delle lesioni dei nervi periferici: risultati definitivi nel trattamento delle lesioni postraumatiche del plesso brachiale e delle lesioni radicolar
A reduction paradigm for output regulation
No full textThe goal of this paper is to provide a reduction paradigm for the design of output regulators which can be of interest for nonlinear as well as linear uncertain systems. The main motivation of the work is to provide a systematic design tool to deal with non-minimum-phase uncertain systems for which conventional high-gain stabilization paradigms are not effective. The contribution of the work is two-fold. First this work extends the nonlinear framework proposed in Marconi et al. (Systems & Control Letters 53 2004) to the case in which the so-called 'immersion into a linear system' does not hold. Furthermore, in the case the uncertain controlled dynamics are linear, we show how the proposed framework leads to a number of systematic design tools of interest in the case of non-minimum-phase linear systems affected by severe uncertainties
An extension of a lemma of Dayawansa and its application in the design of extended observers for nonlinear systems
No full textIn this paper we show how, by extending a classical Lemma due to Dayawansa, it is possible to enhance the theory of robust extended observers so as to cover a wide class of nonlinear systems, namely those systems whose normal form is characterized by “time-dependent gains” in the “string of integrators between input and output”. Such class includes helicopters, quadrotors, robot arms and electric drives
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