1,721,066 research outputs found
Unfolding pathway of apomyoglobin. Simultaneous characterization of acidic conformational states by frequency domain fluorometry
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High-performance liquid chromatographic purification of sodium bis(2-ethyl-1-hexyl)sulphosuccinate from commercial preparations containing near-UV absorbing and fluorescent impurities
No full textStructural and dynamical properties of the folded state of apomyoglobin under denaturing conditions
No full textFluorescence Lifetime Distribution of Intrinsic and Extrinsic Chromophores in Proteins and Model Compounds
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Tryptophanyl contributions to apomyoglobin fluorescence resolved by site-directed mutagenesis
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Amyloid toxicity and platelet-activating factor signaling.
No full textAmyloidosis is the accumulation of insoluble proteinaceous aggregates in vivo and is implicated in many neurodegenerative diseases, including Alzheimer's, Huntington's, and Parkinson's diseases. This article briefly reviews the current knowledge of amyloid aggregate toxicity and inflammatory signaling in the nervous system. In particular, we focus our attention on the role of platelet-activating factor (PAF) as mediator of amyloid cytotoxicit
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