6,575 research outputs found
Preserving the promise : improving the culture of biotech investment /
No full text"Preserving the Promise: Improving the Culture of Biotech Investment critically examines why most biotech startups fail, as they emerge from universities into an ecosystem that inhibits rather than encourages innovation. This 'Valley of Death' squanders our public investments in medical research and with them, the promise of longer and healthier lives. The authors explicate the Translation Gap faced by early stage biotech companies, the result of problematic technology transfer and investment practices, and provide specific prescriptions for improving translation of important discoveries into safe and effective therapies. In Preserving the Promise, Dessain and Fishman build on their collective experience as company founders, healthcare investor (Fishman) and physician/scientist (Dessain). The book offers a forward-looking, critical analysis of 'conventional wisdom' that encumbers commercialization practices. It exposes the self-defeating habits of drug development in the Valley of Death, that waste money and extinguish innovative technologies through distorted financial incentives. Explains why translation of biotech discovery into medicine succeeds so infrequently that it's been dubbed the Valley of Death. Uncovers specific decision-making strategies that more effectively align incentives, improving clinical and financial outcomes for investors, inventor/entrepreneurs, and patients. Examines the critical, early stages of commercialization, where technology transfer offices and Angels act as gatekeepers to development, and where tension between short-term financial and long-term clinical aspirations sinks important technologies. Deconstructs the forces driving biotech, recasts them in a proven conceptual framework, and offers practical guidance for making the system better."--Provided by publisher.Includes bibliographical references and index.Online resource; title from e-book title screen (EbscoHost platform, viewed February 23, 2017)."Preserving the Promise: Improving the Culture of Biotech Investment critically examines why most biotech startups fail, as they emerge from universities into an ecosystem that inhibits rather than encourages innovation. This 'Valley of Death' squanders our public investments in medical research and with them, the promise of longer and healthier lives. The authors explicate the Translation Gap faced by early stage biotech companies, the result of problematic technology transfer and investment practices, and provide specific prescriptions for improving translation of important discoveries into safe and effective therapies. In Preserving the Promise, Dessain and Fishman build on their collective experience as company founders, healthcare investor (Fishman) and physician/scientist (Dessain). The book offers a forward-looking, critical analysis of 'conventional wisdom' that encumbers commercialization practices. It exposes the self-defeating habits of drug development in the Valley of Death, that waste money and extinguish innovative technologies through distorted financial incentives. Explains why translation of biotech discovery into medicine succeeds so infrequently that it's been dubbed the Valley of Death. Uncovers specific decision-making strategies that more effectively align incentives, improving clinical and financial outcomes for investors, inventor/entrepreneurs, and patients. Examines the critical, early stages of commercialization, where technology transfer offices and Angels act as gatekeepers to development, and where tension between short-term financial and long-term clinical aspirations sinks important technologies. Deconstructs the forces driving biotech, recasts them in a proven conceptual framework, and offers practical guidance for making the system better."--Provided by publisher.Innovation Meets the Translation Gap. Stop the Madness and Cure Something ; Into the Valley of Death ; Clinical Promise [not]= Investment Practice ; Velcade, a Biotech Success Story ; Biotechnology and the Future of Pharma ; Why Pharma Should Care About the Valley of Death ; Porter's Five Forces and the Market for Angel Capital ; Out of the Frying Pan: The Fire's Not So Great Either ; Getting to Australia -- Translation Gap 1: Universities Don't Make What Companies Need. When Is an Experiment Ready for the Valley of Death? ; Unintended Consequences of Applying for a Patent ; What if It Doesn't Actually Work? ; Building a Better Mousetrap -- Translation Gap 2: Good Innovation Is Not Always a Good Investment. Due Diligence and Angel Incentives ; What Is Value? ; Angels at the Crux of Invention ; Investment: A Nuanced Decision ; Ready for a Long-Term Relationship With a Science Experiment? ; Investing in Hockey Sticks ; Harps for Angels ; Connecting Innovation to Investment -- Translation Gap 3: Technology Transfer Wastes Money and Innovation. Mitigating Supplier Power ; Preventing Speeding by Closing the Road ; Breaking Old Habits -- Epilogue: Why We Do This.Elsevie
STRATEGIES FOR THE PRESERVATION OF ELECTRONIC RECORDS IN UNIVERSITY LIBRARIES IN NIGERIA
No full textPage 1. 5th of October, 2018 ICERI2018 Local Organising Committee ABSTRACT ACCEPTANCE LETTER This is a confirmation that the abstract entitled: “STRATEGIES FOR THE PRESERVATION OF ELECTRONIC RECORDS IN UNIVERSITY LIBRARIES IN NIGERIA” Author(s): Promise Ilo, Michael Fagbohun, Jerome Idiegbeyan-Ose, Ugwunwa Esse, Nwanne Nwokeoma, Ifeakachuku Osinulu, Olajumoke Olawoyin, Oyeronke Adebayo has been accepted as ORAL presentation at ICERI2018. Name of event: ICERI2018 (11th annual International Conference of Education, Research and Innovation) Dates: 12th-14th of November, 2018 Place: Seville (Spain) Organising entity: IATED IATED Academy. email: [email protected] – Tel.: (+34) 96 344 62 37 – Fax: (+34) 96 206 59 18 iated.or
Incorporating the core international labour standards on freedom of association and collective bargaining into Vietnam's legal system
No full textThis thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.This Dissertation evaluates the potential opportunities, challenges and outcomes attendant on Vietnam’s modernisation effort through the incorporation of International Labour Organisation (ILO) Core International Labour Standards (CILS) on freedom of association and collective bargaining into Vietnam law. The Dissertation shows that although Vietnam is likely to benefit from incorporating the CILS on freedom of association and collective bargaining into its legal system, its constitutional value system is not currently consistent with those of particular ILO CILS. It offers recommendations on pre- substantive and procedural measures necessary to ensure the successful reception of ILO CILS on freedom of association and collective bargaining into Vietnam legal practice.I wish to convey my sincere thanks to the Vietnamese Government for awarding me the 322 Project Scholarships and the British Government for granting me the Overseas Research Students Awards (ORSAS) that made this research financially possible
Managing Stress Among Librarians in Selected University Libraries in Ogun State Nigeria
No full textAbstract
Stress is evident in every workplace, irrespective of type or location. This study revealed that librarians experience stress in federal, state and private universities. However, there are variations in the levels of stress experienced by librarians from private, state and federal universities. According to the findings, there is no significance difference in the causes of stress among the various kinds of libraries studied. The causes are rather evident in physical, environmental, organizational, cultural, and managerial factors. There is high prevalence of stress among women of child bearing age as a result of the interface between home and the workplace. The study equally revealed that job stress has significant effects on effectiveness of librarians in university libraries, resulting in low productivity and output. The negative implications of work stress are recognized as a challenge to both employers and employees. It was also vividly revealed in the study that librarians manage stress through social withdrawal, emotional regulation and wishful thinking. The study therefore recommends positive attitude, ergonomics, self development, cultivating stress-free environment as relevant strategies for coping with stress. It also enjoins the Library and University Management to make provision for constant skill development of librarians, provision of recreational facilities as well as acquisition of necessary facilities among others. The work concludes that since proper management of stress can help harness the best from librarians, it behooves the Management to ensure that the best is put in place so that stress can be reduced to the barest minimum in university libraries
Disciplinary Privilege and the Promise of Decampment: A Response to James Thuo Gathii's “The Promise of International Law: A Third World View”
No full textThis address were delivered at the 114th Annual Meeting of the American Society of International Law, in which the author served as Annual Grotius Lecture Discussant, responding to James Thuo Gathii’s Grotius Lecture: ‘The Promise of International Law: A Third World View’ (available at https://ssrn.com/abstract=3635509). They address what Third World approaches to international law (TWAIL), and the structural racism of the discipline of international law that TWAIL scholarship makes apparent, demand of scholars proceeding from other epistemic locations
Running and Maintaining an ICT-Based Library in a Developing Economy: The Covenant University Experience
No full textInformation and Communication Technology has revolutionized library and Information sen,ices delivery across the globe. The paper examines the Covenant University experience as a model to encourage libraries in developing economies that leveraging with international standards and benchmarks as well as best practices is possible. The superiority of ICT-based library over its manual counterpart is highlighted. This includes: easy integration of various activities, increase in the range of services offered, provision (~f round-the-clock access to
users, etc. The paper discusses inhibiting factors to running a hi-tech library in
Africa and draws heavily from the Covenant University context to underscore basic
infrastructures, skills, values and technological capabilities that are irreducible
imperatives and prerequisites for efficient as well as effective running and
maintenance of an ICT-based library. It concludes by admonishing that African
libraries must not be left behind in this era of flat world and universal as 11·ell as
unfettered access to global information. The panacea to intellectual inequity and
lopsidedness between the developed and developing world is the application of ICT
in information management and dissemination
Libraries and Librarians in the 21st Century: A new perspective
No full textThe 21st century has indeed witnessed a new dimension in the area of library
practice. This paper discusses libraries and librarians in this century. It portrays
vividly the traditional libraries which were devoid of any form of ICT, as well as the
librarians who lacked skills necessary for enhancing library services. The paper
also presents the 2 rr century libraries as those characterized by the use of ICT in the
acquisition, processing, preservation and accessibility of materials. It highlights the
new roles of the present day librarians who have eventually become image makers,
facilitators, intrusion server managers, online cataloguers, system analysts, web
designers etc. The paper recommends the need for the 2 r century librarians to
train and retrain themselves while parent institutions should ensure that librarians
are sponsored to both local and international conferences. Professional
Associations are also urged to organize seminars/workshops for librarians at
subsidized rates. The paper finally concludes that as libraries continue to change;
librarians should strive to acquire necessary skills which will position them to .fit in
and perform maximally in the present day libraries and those of the.futur
Cataloguing and Classification in an ICT Age: Matters Arising
No full textThe paper discusses the current trends in cataloguing and classification of library
materials in the information and communication technology era. There is
outstanding evidence that ICT has improved cataloguing activities, but has at the
same time given rise to some issues of concern to the library, librarian and the
users. These identified issues include threat to the position of the cataloguer,
requisite skills, infrastructure, training, software etc. Suggestions given on how to
derive maximum benefits include capacity building through self-development,
review of curriculum, constant power supply and regular user bibliographic
instruction
Acquisition,Preservation and Accessibility of Indigenous Knowledge in Academic Libraries in Nigeria: The Place of ICT
No full textNigerians interact well with their natural environment, culminating in the
accumulation of diverse experiences. These experiences result in a body of
indigenous knowledge which though unique to a given society or culture,
forms part of the information needed by researchers. In spite of the place of
indigenous knowledge in enriching academic libraries, its documentation
and preservation for posterity have hitherto posed tremendous challenges.
However, the emergence of information and communication technology
(JCT) has provided opportunities for librarians to interact with their host
and other communities in a bid to document various indigenous information
that may be of use to the library.
This paper discusses various indigenous knowledge practices in Nigeria
·,such as language, medicine, agriculture, family, marriage and highlights
the benefits of indigenous knowledge which include contributions to
community development, exchange of cultural information, recognition of
indigenous community in the global setting, etc. The paper also discuss
various ICT facilities required in documentation and preservation of
indigenous knowledge like recorder, photographic camera, video camera,
tapes, films, CDs, computer etc. Problems hindering the use of ICT which
are discussed include lack of fund, power failure and attitude of indigenous
communities and distortion of information among others. For the purpose
of improvement, the paper recommends collaboration with multinational
organizations and donor agencies for the purpose of fund generation,
librarians ' skill acquisition, respect of indigenous copyright issues, and
persuading the custodians of indigenous information on the need to release
informatio
Resource Sharing in Academic Libraries in Nigeria: A Digital Imperative
No full textThis paper exwnined the past e./forts made by Nigerian libraries towards
sharing of resources and enum.erated the benefits accruing from such
ventures. It also identified the necessary conditions for digital resource
sharing such as fund, c01nputers, internet availability, constant power
supply, standard and up-to-date union catalogue, and proper
maintenance skills among others. 111e poor state of these conditions in
Nigeria were highlighted and the recommendations include generation of
fund for digital facilities, review of library school curriculum, staff
training, and acquisition of computer skills and maintenance of ·
standard
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