1,720,996 research outputs found
Evidence for 15 genetically determined electrophoretic variants of transcobalamin II in rabbit serum.
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Rapid selection of phge-resistant mutants of Streptococcus thermophilus by immunoselection and cell sorting
No full textA new electrophoretic variant of vitamin D binding protein (post-albumin) in cattle serum
No full textRapid selection of phge-resistant mutants of Streptococcus thermophilus by immunoselection and cell sorting
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Simultaneous identification of antibodies to brucella abortus and Staphylococcus aureus in milk samples by flow cytometry
No full textExperimental phage therapy against Staphylococcus aureus in mice.
No full textThe present study describes a bacteriophage (M-Sa) active against Staphylococcus aureus, including methicillin-resistant staphylococcal strains. When inoculated into mice simultaneously with S. aureus A170 (10(8) CFU/mouse), phage (10(9) PFU) rescued 97% of the mice; when applied to nonlethal (5 X 10(6) CFU/mouse) 10-day infections, the phage also fully cleared the bacteria. The phage M-Sa, delivered inside macrophages by S. aureus, kills the intracellular staphylococci in vivo and in vitro. The phage can also prevent abscess formation and reduce the bacterial load and weight of abscesses. These results suggest a potential use of the phage for the control of both local and systemic human S. aureus infections
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