44,923 research outputs found

    Grau & Müller, Wallendorf i. Th.

    No full text
    GRAU & MÜLLER, WALLENDORF I. TH. Grau & Müller, Wallendorf i. Th. ( -

    Edict, Daß aus Sr. Königlichen Majestät Lande Kein Getreyde nach Sachsen verführet werden soll : De dato Berlin, den 21. Julii 1719.

    No full text
    Vorlageform des Erscheinungsvermerks: Magdeburg, Druckts Johann Daniel Müller, Königl. Preuß. privil. Buchdrucker

    Patent, Daß Die auf Magdeburg gehende Heer-Strasse Von denen Fuhr-Leuthen, Gutschern und Kärnern nicht umfahren werden soll : Sub dato Berlin, den 10. Februarii 1724. / [Fr. Wilhelm]

    No full text
    Autopsie nach Ex. der ULB Sachsen-AnhaltVorlageform des Erscheinungsvermerks: Magdeburg, Gedruckt bey Johann Daniel Müller, Königl. Preuß. privil. Buchdrucker

    Goethes "Faust" / von Joachim Müller

    No full text
    GOETHES "FAUST" / VON JOACHIM MÜLLER Goethes "Faust" / von Joachim Müller (1) Cover (1) Titelseite (2) Inhaltsverzeichnis (3) I. Methodische Grundlagen (4) II. Die Faustdichtung (10) III. Schriftentum (66

    IN03148 Devanagala Rock Inscription of Parākramabāhu I - Müller (1883)

    No full text
    IN03148 Devanagala Rock Inscription of Parākramabāhu I - Transcript and Translation Source: Müller, Edward. (1883). Ancient Inscriptions in Ceylon. London: Trubner & Co., pp. 60, 87, 120, no. 135

    Müller glia activation in response to inherited retinal degeneration is highly varied and disease-specific

    No full text
    Despite different aetiologies, most inherited retinal disorders culminate in photoreceptor loss, which induces concomitant changes in the neural retina, one of the most striking being reactive gliosis by Müller cells. It is typically assumed that photoreceptor loss leads to an upregulation of glial fibrilliary acidic protein (Gfap) and other intermediate filament proteins, together with other gliosis-related changes, including loss of integrity of the outer limiting membrane (OLM) and deposition of proteoglycans. However, this is based on a mix of both injury-induced and genetic causes of photoreceptor loss. There are very few longitudinal studies of gliosis in the retina and none comparing these changes across models over time. Here, we present a comprehensive spatiotemporal assessment of features of gliosis in the degenerating murine retina that involves Müller glia. Specifically, we assessed Gfap, vimentin and chondroitin sulphate proteoglycan (CSPG) levels and outer limiting membrane (OLM) integrity over time in four murine models of inherited photoreceptor degeneration that encompass a range of disease severities (Crb1rd8/rd8, Prph2+/Δ307, Rho-/-, Pde6brd1/rd1). These features underwent very different changes, depending upon the disease-causing mutation, and that these changes are not correlated with disease severity. Intermediate filament expression did indeed increase with disease progression in Crb1rd8/rd8 and Prph2+/Δ307, but decreased in the Prph2+/Δ307 and Pde6brd1/rd1 models. CSPG deposition usually, but not always, followed the trends in intermediate filament expression. The OLM adherens junctions underwent significant remodelling in all models, but with differences in the composition of the resulting junctions; in Rho-/- mice, the adherens junctions maintained the typical rod-Müller glia interactions, while in the Pde6brd1/rd1 model they formed predominantly between Müller cells in late stage of degeneration. Together, these results show that gliosis and its associated processes are variable and disease-dependent

    Gebirgsansicht vom Piz Vizzan bei Andeer : vom Piz d'Emet - Gelbhorn

    No full text
    gezeich. d. 22. August 1873 von [Johann] Müller-Wegmann"Lith. F.Lips, Berne. Jmpr.mec."Unten links: Jahrbuch des S.A.C. Bd. I
    corecore