1,836 research outputs found
Medical utilization and cost of women with stress urinary incontinence in outpatient clinics
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A ganglion cyst of posterior cruciate ligment detected by ultrasonographic examination: a case report.
No full textEstimation of expected utility gained from the helmet law in Taiwan by quality adjusted survival time.
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Additional role of nicotinic acid hydroxylase for the transformation of 3-succinoyl-pyridine by Pseudomonas sp. JY-Q
No full textApplied Environmental Microbiology, 87, e02740-20Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY. The final version is available through the publisher’s platform.Nicotine and nicotinic acid (NA) are both considered to be representatives of N-heterocyclic aromatic compounds, and their degradation pathways have been revealed in Pseudomonas species. However, the cooccurrence of these two pathways has only been observed in Pseudomonas sp. strain JY-Q. The nicotine pyrrolidine catabolism pathway of strain JY-Q consists of the functional modules Nic1, Spm, and Nic2. The module enzyme, 3-succinoylpyridine monooxygenase (Spm), catalyzes transformation of 3-succinoyl-pyridine (SP) to 6-hydroxy-3-succinoyl-pyridine (HSP). There exist two homologous but not identical Spm enzymes (namely, Spm1 and Spm2) in JY-Q. However, when spm1 and spm2 were both in-frame deleted, the mutant still grew well in basic salt medium (BSM) supplemented with nicotine as the sole carbon/nitrogen nutrition, suggesting that there exists an alternative pathway responsible for SP catabolism in JY-Q. NicAB, an enzyme accounting for NA hydroxylation, contains reorganized domains similar to those of Spm. When the JY-Q_nicAB gene (nicAB in strain JY-Q) was introduced into another Pseudomonas strain, one that is unable to degrade NA, the resultant recombinant strain exhibited the ability to transform SP to HSP, but without the ability to metabolize NA. Here, we conclude that NicAB in strain JY-Q exhibits an additional role in SP transformation. The other genes in the NA cluster, NicXDFE (Nic2 homolog), then also exhibit a role in subsequent HSP metabolism for energy yield. This finding also suggests that the cooccurrence of nicotine and NA degradation genes in strain JY-Q represents an advantage for JY-Q, making it more effective and flexible for the degradation of nicotine.China Postdoctoral Science Foundationhttps://login.libproxy.rpi.edu/login?url=https://doi.org/10.1128/AEM.02740-2
Late dialysis rate for coronary artery grafting patients with moderate-to-severe renal impairment: somparison between off-pump and conventional methods
No full textExpression of Cyr61(CCN1) in human oral squamous cell carcinoma: an independent marker for poor prognosis.
No full textNumerical investigation on the aeroelastic instability of a complete aircraft model
No full textA nonlinear aeroelastic analysis system has been developed using the coupled numerical techniques of computational fluid dynamics (CFD) and computational structural dynamics (CSD) in the present study and the analysis system has been applied to an actual aircraft design procedure to examine aeroelastic stabilities. An aerodynamic analysis is performed using the transonic small disturbance (TSD) theory for computational efficiency and the results are compared with experimental data. An aeroelastic analysis in the time domain is performed to obtain the flutter boundaries of the aircraft model. Finally, the various effects of launchers and control surfaces are investigated
Cost-utility analysis of outpatient exercise training after coronary artery bypass grafting
No full textCANONICAL ABERRATION THEORY FOR CALCULATING HIGHER-ORDER CHROMATIC ABERRATIONS
No full textCanonical aberration theory has been developed in previous papers by the author. In the present study, the canonical aberration theory has been used to deal with first- and third-order chromatic aberrations (including position and momentum aberrations at an arbitrary observation plane) for rotationally symmetrical optical systems. All first- and third-order chromatic aberrations have been expressed in canonical matrix representations, which are general in nature and appropriate for computer calculations.Physics, AppliedSCI(E)3ARTICLE41962-19676
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