1,847 research outputs found
Filmske adaptacije nekaterih avstralskih romanov
No full textOsrednja tema pričujočega diplomskega dela je prenos štirih avstralskih romanov na filmska platna, oziroma njihove adaptacije. Natančneje gre za naslednje romane: Piknik pri Hanging Rocku, pisateljice Joan Lindsay, V središču viharja, Nobelovega nagrajenca Patricka Whita, Oscar in Lucinda, dvakratnega Bookerjevega nagrajenca Petra Careyja ter Moja sijajna kariera pisateljice Miles Franklin. V procesu snemanja filma po knjižni predlogi lahko med njima nastane precej razlik. Nekateri deli romana (npr. vsebina in liki) so v filmu spremenjeni, okrnjeni ali dodani. Diplomsko delo pobližje predstavi avstralsko književnost ter film, naredi kratek pregled tipologij adaptacij, ključni del pa predstavlja analiza romanov in njihovih filmskih adaptacij. Ugotovljene razlike in podobnosti ne vplivajo na kakovost filmske priredbe in dokaj zvesto podajajo vsebino romana v filmski obliki.The central subject of the present thesis is the adaptation of four australian novels into film. Specifically it is about following novels: Picnic at Hanging Rock, of australian author Joan Lindsay, The eye of the storm of Nobel laureate Patrick White and Oscar and Lucinda of Peter Carey, who has won the Booker prize twice and My brilliant career written by Miles Franklin. During the process of making a film based on a novel, many changes appear. Parts of the novel like characters and subplots, are sometimes changed, subtracted or added. The thesis in more details discusses australian literature and film, typologies of adaptations, the key part in thesis discusses analysis of novels and their movie adaptations. The established differences and similarities do not affect the quality of the adaptation and the film relatively faithfully transfers the story in a different form
Polemon neuwiedi Jan 1858
No full textPolemon neuwiedi (Jan, 1858) MATERIAL EXAMINED. — No available specimen. DISTRIBUTION. — In Togo, this species has been mentioned from "Klien Popo", now Aneho, by Sternfeld (1908a-b, 1909) and Loveridge (1944: 173). Werner (1898; as Miodon gabonensis) mentioned from Togo a specimen of Polemon gabonensis (Duméril, 1858). The current distribution of this species extends from eastern Nigeria to Congo (Chippaux 2006). It is hence likely that Werner's specimen should be referred to Polemon neuwiedi, although another taxon of the same genus cannot be ruled out. This confusion may also apply to the Togolese record of Polemon collaris (Peters, 1881) in Werner (1898). This author was merely followed by Sternfeld (1908b, 1909) but Loveridge (1944) doubted about the occurrence of this latter species in Togo. Prosymna gregerti Mocquard, 1906 (Fig. 7) MATERIAL EXAMINED. — 1 specimen (MNHN 2006.2190), Mango. MORPHOLOGY. — TL 273 mm; 15 MSR, smooth; 151 Ven smooth; 35 Sc; anal single; 5 supralabials; 7 infralabials; 1 preocular; 2 postocular; temporal scale formula 1 + 2 + 3. DISTRIBUTION. — This species inhabits Sudan savannahs (ER I). Previously it had been described from Togo (Mango) by Sternfeld (1908b) as Prosymna meleagris var. collaris Sternfeld, 1908. This form was subsequently synonymized with Prosymna meleagris (Reinhardt, 1843) by Loveridge (1958). Trape & Mané (2006b) revalidated Prosymna gregerti Mocquard, 1906 as a valid taxon. This species was mentioned fom northern Togo by Villiers (1951) and Villiers & Condamin (2005).Published as part of Segniagbeto, Gabriel Hoinsoude, Trape, Jean François, David, Patrick, Ohler, Annemarie, Dubois, Alain & Glitho, Isabelle Adolé, 2011, The snake fauna of Togo: systematics, distribution and biogeography, with remarks on selected taxonomic problems, pp. 325-360 in Zoosystema 33 (3) on page 345, DOI: 10.5252/z2011n3a4, http://zenodo.org/record/454701
Why is unemployment so high in Bulgaria?
No full textThe author seeks to determine the main factors behind poor labor market outcomes in Bulgaria. Unemployment in Bulgaria is high and of long duration. The accumulation of the unemployment stock has been caused by relatively high inflows into unemployment coupled with limited outflows. These features of the Bulgarian labor market are typical of other transition economies in Central Europe and exploring their sources is of broad interest. The author focuses on determinants of and constraints to job creation. He uses data on job creation and job destruction from a survey of employment in all registered firms. He finds that the source of large inflows into unemployment is intensive enterprise restructuring associated with a high pace of job reallocation. However, job creation falls short of job destruction. Three main factors account for the limited job creation and hiring, and thus for low outflows from unemployment: a) The unfriendly business environment, reflected by a low rate of new firm formation, and a relatively small, small and medium enterprise sector. b) Labor market rigidities, including excessive hiring and firing costs. c) Skill and spatial mismatches brought about by enterprise restructuring, as well as low skills and marginalization of the long-term unemployed who cannot successfully compete for new jobs. The author recommends a three pronged strategy to improve labor market performance: (1) removing bureaucratic constraints to entry and expansion of firms; (2) enhancing labor market flexibility through lowering hiring and firing costs; and (3) improving the educational system so as to equip workers with broad and portable skills.Environmental Economics&Policies,Labor Policies,Labor Markets,Public Health Promotion,Health Monitoring&Evaluation,Environmental Economics&Policies,Labor Markets,Health Monitoring&Evaluation,Labor Standards,Banks&Banking Reform
Antithrombotic therapy and assessment for bleeding diathesis in elective gastrointestinal endoscopy - Expert Opinion Statement on behalf of the Swiss Society of Gastroenterology.
No full textTheoretical criminology, 1992
No full textThis thesis examines the criminological frames of reference as extracted from the scholarly literature on crime causation. First, a cursory review of the theoretical criminological literature from Jan. 1, 1970 to Jan. 1, 1990 disclosed seven major crime causations: (1) Classical criminology (2) Positive School (3) Biological factors (4) Personality and psychological factors (5) Socio-economic factors (6) Sociological factors (7) Specific type of crime theory I then selected and analyzed representative theories, theorists, and research studies from each of these seven categories
Retinal arteriolar and venular diameters are widened in patients with schizophrenia
No full textDr Liu reports grants from the National Key R&D Program of China(2018YFC1314600), outside the submitted work. This work was supported by the Czech Health Research Council, Ministryof Health of the Czech Republic (Grant Project No. NV16-27243A).Sery, O (corresponding author), Masaryk Univ, Dept Biochem, Lab Neurobiol & Mol Psychiat, Fac Sci, Brno, Czech Republic ; Acad Sci Czech Republ, Inst Anim Physiol & Genet, Lab Neurobiol & Pathol Physiol, Prague, Czech Republic.
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La mémoire dans deux romans de Patrick Modiano : Une étude comparative
No full textThis essay examines how the concepts of memory and oblivion are manifested and expressed in two novels written by the french author and Nobel laureate Patrick Modiano. These novels are Chien de printemps (1993) and Dans le café de la jeunesse perdue (2007). For Modiano, the concepts of memory and oblivion are central to his literary production. The memory and oblivion are central to the creation and the maintaining of our human identity, our history. The memory is also a function of the language. Without a language, there will be no memory. Thus the formation of the language is important for the memory creation of the small child. The study will be based upon the theoretical work done by the french sociologist Maurice Halbwachs, followed by studies by the german egyptologist Jan Assmann and also by the german professor of literature Aleida Assmann. We will utilise the four-dimensional memory typology defined and developed by Jan and Aleida Assmann. It distinguishes the memory into four dimensions; the individual, collective, cultural and national memory. Our main goal is thus to examine and identify how the memory and the oblivion are handled, manifested and expressed in the two chosen novels
Cycling on the Verge? Exploring the Place of Utility Cycling in Contemporary New Zealand Transport Policy
No full textEfforts to increase cycling as a mode of transport (utility cycling) occur at central, regional and local levels of government through a range of supportive strategies, research, and guidelines. Despite these efforts, utility cycling levels in New Zealand have remained persistently low. This thesis examines the apparent disparity between policy intent and policy result, using a discourse analytical approach. It examines how cycling is positioned in contemporary New Zealand transport policy documents, and explores whose priorities are shaping transport policy with what implications for utility cycling.
This study uses a critical discourse analysis (CDA) approach to analyse the land transport documents from across the institutions of government. The CDA approach, grounded in the work of van Dijk and Fairclough, draws on ideas from the interpretive tradition of discourse analysis, inspired by Foucault’s concepts of knowledge and power. This approach reveals the position of utility cycling by exposing the framing, dominant discourses, and discursive strategies that privilege certain transport objectives and activities over others.
The findings show transport is promoted almost exclusively by central government as an activity to facilitate economic growth and efficiency, despite its potential (and actual) impacts on health and well-being, social justice, and environmental sustainability. The discursive practices of the government privilege private motor vehicle use, helping to both legitimate and maintain that privilege at all levels of government, while positioning utility cycling as a marginalised mode of transport.
This thesis contributes to scholarship on utility cycling and land transport policy in New Zealand by identifying how the discursive strategies of government control the position of utility cycling in New Zealand. This study underscores the need for a central government-led, long-term strategic vision for a genuinely integrated, multi-modal transport system, in order for the benefits of utility cycling to be fully maximised
GENE THERAPY FOR NEOPLASTIC DISEASES
No full textIntroduction / Brian E. Huber -- Pt. I. The beginning: strategy and ethics -- Gene therapy strategies for treating neoplastic disease / Brian E. Huber -- The impact of gene therapy on medicine and society / William N. Kelley -- General discussion 1 / Chair: Brian E. Huber -- Pt. II. Gene transfer technology I - - Cationic liposomes for direct gene transfer in therapy of cancer and other diseases / Hassan Farhood, Xiang Gao, Kyonghee Son, Ya- Yun Yang, John S. Lazo, Leaf Huang, James Barsoum, Remo Bottega, and Richard M. Epand -- High-efficiency gene transfer mediated by adenovirus-polylysine-DNA complexes / David T. Curiel -- Pt. III. Gene transfer technology II -- The retroviral vector: replication cycle and safety considerations for retrovirus-mediated gene therapy / Kathleen Boris-Lawrie and Howard M. Temin -- Retroviral vectors for use in human gene therapy for cancer, Gaucher disease, and arthritis / Pauld. Robbins, Hideaki Tahara, Gunhild Mueller, Greg Hung, Alfred Bahnson, Laurence Zitvogel, Joanna Galea-Lauri, Toya Ohashi, Ken Patrene, Sallie S. Boggs, Christoptier H. Evans, John A. Barranger, and Michael T. Lotze -- Adenovirus-mediated in vivo gene transfer / Steven L. Brody and Ronald G. Crystal -- Pt. IV. Engineering drug sensitivity and drug resistance: implications in cancer therapy -- Virus-directed enzyme/prodrug therapy (VDEPT): selectively engineering drug sensitivity into tumors / Brian E. Huber, Cynthia A. Richards, and Elizabeth A. Austin -- Therapeutic strategies using c-erbB-2 promoter-controlled drug activation / Karol Sikora, Jonathan Harris, Helen Hurst, and Nick Lemoine -- Gene transfer of drug resistance genes: implications for cancer therapy / Michael M. Gottesman, Ursula A. Germann, Ivan Aksentijevich, Yoshikazu Sugimoto, Carol O. Cardarelli, and Ira Pastan -- General discussion 2 / Chair: Brian E. Huber -- Pt. V. Immunomodulation through gene therapy: implications for neoplastic disease -- Direct gene transfer for me understanding and treatment of human Disease / Gregory E. Plautz, Elizabeth G. Nabel, Bernard Fox, Zhi- Yong Yang, Michele Jaffe, David Gordon, Alfred Chang, and Gary J. Nabel -- Monoclonal antibody gene transfer: implications for tumor- specific cell-mediated cytotoxicity / F. James Primus, Margaret D. Finch, Scott A. Wetzel, Ann Maria Masci, Jeffrey Schlom, and S. V. S. Kashmiri -- Retrovirus-mediated gene transfer of the human y- IFN gene: a therapy for cancer / Brad Howard, Michelle Burrascano, Tammy McCallister, Kim Chong, Ramarao Gangavalli, Liv Severinsson, Douglas J. Jolly, Timothy Darrow, Carol Vervaert, Zeinhab Abdel- Wahab, Hilliard F. Siegler, and Jack R. Barber -- The use of gene- modified tumor-infiltrating lymphocytes for cancer therapy / Patrick Hwu and Steven A. Rosenberg -- General discussion 3 / Chair: Gary J. Nabel -- Pt. VI. Implications of gene therapy in bone marrow transplantation and hematopoietic cells -- Gene marking and autologous bone marrow transplantation / Malcolm K. Brenner, Donna R. Rill, Robert C. Moen, Robert A. Krance, Helen E. Heslop, Joseph Mirro, Jr., W. French Anderson, and James N. Ihle -- Gene transfer into hematopoietic cells: implications for cancer therapy / Cynthia E. Dunbar, David M. Bodine, Brian Sorrentino, Robert Donahue, Kevin McDonagh, Michele Cottler-Fox, Joyce O'shaughnessy, Kenneth Cowan, Charles Carter, Sandra Doren, Aliza Cassell, and Arthur W. Nienhuis -- General discussion 4 / Chair: Malcolm K. Brenner -- Pt. VII. Other implications of gene therapy cancer treatment -- Development of antisense therapeutics: implications for cancer gene therapy / John F. Milligan, Robert J. Jones, Brian C. Froehler, and Mark D. Matteucci -- H-ras ribozyme-mediated alteration of the human melanoma phenotype / Yukinori Ohta, Takeshi Tone, Toshiya Shitara, Tadao Funato, Lu Jiao, Brandon I. Kashfian, Emmy Yoshida, Mark Horng, Patricia Tsai, Karen Lauterbach, Mohammed Kashani-Sabet, Viva Ann Florenes, Oystein Fodstad, and Kevin J. Scanlon -- Gene therapy and endothelial cell targeting for cancer / Robert R. Evans, Thierry P. Calmels, Bruce R. Pitt, Margaret A. Brookens, Candace S. Johnson, Ruth A. Modzelewski, and John S. Lazo -- Mechanisms of action of the p53 tumor suppressor and prospects for cancer gene therapy by reconstitution of p53 function / Klaus Roemer and Theodore Friedmann -- Pt. VIII. Practical development of gene therapy programs -- Designing clinical trials of somatic gene therapy / Fred D. Ledley. -- Human gene therapy: suggestions for avoiding liability / Julie Gage Palmer -- Transduction, expression, and secretion of human glucocerebrosidase by murine myoblasts / Vijaya Bansal, Patricia Mowery-Rushton, Lorrie Lucht, Juan Li, Alfred Bahnson, Simon C. Watkins, and John A. Barranger -- Poster papers -- Double-stranded phosphorothioate oligonucleotide modulation of gene expression / K.C. Ess, J.J. Hutton, and B.J. Aronow -- Engineered MHC class I Antigens as allogenizing molecules: potential for tumor immunotherapy / Krishn a V. Kesari and Jan Geliebter -- High-titer retroviral vectors for efficient transduction of functional genes into murine hematopoietic stem cells / Robert G. Hawley -- Receptor-mediated gene transfer into hepatic cells using asialogiycoprotein-labeled liposomes / K. Koike, T. Hara, Y. Aramaki, S. Takada, and S. Tsuchiya -- Mechanisms of tumor regression of INF gene-transduced meth: a cells transplanted in mice / Yoshikazu Koshita, Yoshinori Itoh, Shigeyuki Fujii, Hiroshi Neda, Minoru Takahashi, Naoki Watanabe, Yutaka Kohgo, and Yoshiro Niitsu -- Successful transfection of biotinylated B-galactosidase gene conjugated with transferrin into leukemia cells and interleukin-2-stimulated lymphocytes via transferrin receptor / H. Neda, M. Takahashi, Y. Itoh, Y. Koshita, T. Matsuyama, N. Watanabe, Y. Kohgo, and Y. Niitsu -- Subject index -- Index of contributor
Vibriosis in bivalves: Review of recent molecular, biochemical, and physiological studies
No full textThe emergence of new vibriosis in the European Atlantic coasts has been associated with mass mortalities of molluscs causing important economic losses. For example, Vibrio carchariae, a bacteria already isolated from shark, has been associated with a severe Haliotis epizooty in hatchery. In oysters, Crassostrea gigas, a strain closely related to Vibrio splendidus is suspected to be associated with summer mortalities. Some other pathogenic vibrios have been also isolated a few years ago: Vibrio tapetis which provokes the Brown Ring Disease in the Manila clams Ruditapes philippinarum; Vibrio splendidus which induces conchyoline deposit in Pecten maximus; and also Vibrio pectenicida which causes larval scallop mortalities in hatchery. The list is not exhaustive. Several tools have been developed to detect these pathogenic vibrios. They include serological procedures using polyclonal and monoclonal antibodies and ELISA tests, biochemical criteria and molecular methods based on the 16S or 23S rRNA nucleic acid probes hybridization. Molecular identification of V. tapetis and V. pectenicida has been recently done by dot blot hybridation using specific 16S rDNA probes and a SSP-PCR protocol method has allowed V. tapetis detection in individual diseased and asymptomatic clams. This last method suggests a potential utilization in commercial hatcheries to confirm V. tapetis free water and clams. If the virulence factors of fish pathogenic vibrios have been yet identified, little knowledge exist in mollusc pathogenic vibrios. Bivalve pathogenic vibrios are host specific, excepted V. splendidus which presents various variants depending on the host species. In this last vibrio, V. splendidus, some common mechanism mediated by molecular factors could be suspected. The interactions of the vibrios with the clam's tissus or hemocytes have been used to developed in vitro biotests to evaluate their pathogenicity. Accordind to these tests, in V. tapetis, adherence and hemocyte lysis factors have been yet identified. With this test, a toxin from Vibrio pectenicida, responsible of hemocyte lysis, was partially purified. It was a small molecule (< 3Kdal), no-proteinic different to cilio-static toxin described by Nottage and Birkbeck. This molecule is probably common at different pathogenic vibrios. In bacteria, virulence factors are generally carried by plasmids. Two or three plasmids have been yet detected in V. tapetis, but the role of these plamids in pathogenicity is still not demonstrated. In conclusion, studies of these interaction models, vibrio-bivalve, allow to develop original comparative researchs, in particular characterisation of adherence factors and toxins in vibrios but also characterisation of the immune defence mechanisms against vibrios, in particular identification of anti-bacterial substances.TR: CS0117498 'Disney's Coronado Springs Resort, January 21-25, 2001, Lake Buena Vista, Florida.'/ 'The international trienniel conference & exposition of National Shellfisheries Association, American Fisheries Society Fish Culture Section, World Aquaculture Society'--Cover./ Includes author and subject indexes
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