6,397 research outputs found
Lysophosphatidic acid (LPA) inhibits serum starvation induced-autophagy of PC-3 human prostate cancer cell-line.
Membrane recruitment of Aut7p in the autophagy and cytoplasm to vacuole targeting pathways requires Aut1p, Aut2p, and the autophagy conjugation complex.
Identification of icp11, the most highly expressed gene of shirmp white spot syndrme virus
The itinerary of a vesicle component, Aut7p/Cvt5p, terminates in the yeast vacuole via the autophagy/Cvt pathways.
Light bullets in the spatiotemporal nonlinear Schrodinger equation with a variable negative diffraction coefficient
We report approximate analytical solutions to the (3+1)-dimensional spatiotemporal nonlinear Schrodinger equation, with the uniform self-focusing nonlinearity and a variable negative radial diffraction coefficient, in the form of three-dimensional solitons. The model may be realized in artificial optical media, such as left-handed materials and photonic crystals, with the anomalous sign of the group-velocity dispersion (GVD). The same setting may be realized through the interplay of the self-defocusing nonlinearity, normal GVD, and positive variable diffraction. The Hartree approximation is utilized to achieve a suitable separation of variables in the model. Then, an inverse procedure is introduced, with the aim to select a suitable profile of the modulated diffraction coefficient supporting desirable soliton solutions (such as dromions, single-and multilayer rings, and multisoliton clusters). The validity of the analytical approximation and stability of the solutions is tested by means of direct simulations
Lysophosphatidic acid inhibits serum deprivation-induced autophagy in human prostate cancer PC-3 cells
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