2,780 research outputs found
Magnesium bromide promoted Barbier-type intramolecular cyclization of halo-substituted acetals, ketals, and orthoesters
No full textPolymeric micelles and the Dy-166/Ho-166 generator: A study of the loading mechanism of Dy/Dy-166 and Ho-166 into PCL-b-PEO polymeric micelles for imaging and cancer treatment
No full textA radioisotope used in radionuclide therapy is Holmium-166 (Ho-166). The treatment effectiveness of Ho-166 could be improved by the use of a so called in vivo Dysprosium-166(Dy-166)/Ho-166 generator. The application of this generator is hindered by an effect called internal conversion (IC). This affect can arise after the decay of Dy-166 to Ho-166, which can cause separation of Ho-166 from its carrier.Polymeric micelles might form a solution in the application of the Dy-166/Ho-166 generator in radionuclide therapy. The main goal of this thesis was to investigate and understand the loading mechanism of metallic species and polymeric micelles with a focus on the loading of Dy/Dy-166 and Ho-166. It was found that it was not effective to load metallic species (Dy/Dy-166) as free ions or as solid precipitates. Loading metallic species as aqueous hydroxides showed to be crucial for achieving a good loading and high stability. The second goal was to study if polymeric micelles were able to retain Ho-166 inside their core under the effects of internal conversion. No additional losses of Ho-166 were found when Dy/Dy-166 and Ho-166 were loaded into the micelles. It was concluded that the PCL-PEO micelles prevented the loss of Ho-166 under internal conversion effects.Applied Science
The importance of an accurate CH4 vibrational partition function in full dimensionality calculations of the H+CH4 -> H2+CH3 reaction
No full textBowman JM, Wang DY, Huang XC, Huarte-Larranaga F, Manthe U. The importance of an accurate CH4 vibrational partition function in full dimensionality calculations of the H+CH4 -> H2+CH3 reaction. JOURNAL OF CHEMICAL PHYSICS. 2001;114(21):9683-9684
Study on Superdeformed Bands of Dy-152 and Its Neighboring Nuclei
No full textDy-152 is the first observed superdeformed nucleus, whose band structure reflects the typical distribution of high j low Omega orbitals of superdeformed nuclei in A similar to 150 mass region. The particle-number conserving treatment of the cranked shell model with monopole and quadrupole paring interactions is adopted to investigate the observed six superdeformed bands in Dy-152. The pi[523]7/2 orbital is emphasized for the first time to interpret the microscopic structure of band 2 and 3 of Dy-152. A new comprehension is proposed on the basis of ever existing experimental and theoretical results, and the reliability is illustrated by several superdeformed bands of neighboring nuclei.Physics, Fluids & PlasmasSCI(E)EI中国科学引文数据库(CSCD)05408-4111
beta-delayed proton decays and spin assignments for Tb-140, Dy-141 and Dy-143
No full textThe proton-rich isotopes Tb-140 and Dy-141 were produced via the fusion evaporation reaction Ca-40+ Cd-106. Their beta-delayed proton decays were studied by p-gamma coincidence in combination with a He-jet tape transport system, and half-lives, proton energy spectra, gamma-transitions following the proton emission, as well as beta-delayed proton branching ratios to the low-lying states in the grand-daughter nuclei were determined. Comparing the experimental data with statistical model calculations, the ground-state spins of Tb-140 and Dy-141 were found to be consistent with 7 and 9/2, respectively. The configuration-constrained nuclear potential energy surfaces (NPES) of Tb-140 and Dy-141 were calculated using the Woods-Saxon-Strutinsky method, which suggest the ground-state spins and parities of Tb-140 and Dy-141 to be 7(+) and 9/2(-), respectively. In addition, the configuration-constrained NPES of Dy-143 were calculated, which predict a 1/2(+) ground state and a 11/2(-) isomer with excitation energy of 198 keV. These findings are consistent with our previous experimental data on Dy-143 reported in Eur. Phys. J. A 16, 347 (2003).Physics, NuclearPhysics, Particles & FieldsSCI(E)3ARTICLE137-402
YC-1 inhibits HIF-1expression in prostate cancer cells: contribution of Akt/NFB signaling to HIF- accumulation during hypoxia.
No full textCHM-1, a novel synthetic quinolone with potent and selective antimitotic antitumor activity against human hepatocellular carcinoma in vitro and in vivo.
No full textMoscatilin Repressed Lipopolysaccaride-Induced HIF-1alpha accumulation and NF-kappaB Activation in Murine RAW264.7 Cells.
No full textExpression of inhibitory natural killer receptors on tumor-infiltrating CD 8 T lymphocyte lineage in human endometrial carcinoma.
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