3,501 research outputs found

    sj-pdf-1-ang-10.1177_00033197211059693 – Supplemental Material for Dose-Response Association Between Bilirubin and Cardiovascular Disease: A Systematic Review and Meta-analysis

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    Supplemental Material, sj-pdf-1-ang-10.1177_00033197211059693 for Dose-Response Association Between Bilirubin and Cardiovascular Disease: A Systematic Review and Meta-analysis by Lei Zuo, Jun Huang, Hongyue Zhang, Bing Huang, Xiaoyi Wu, Li Chen, Sujian Xia, Xiaomei Dong and Guang Hao in Angiology</p

    sj-pdf-1-ang-10.1177_00033197221094409 – Supplemental Material for Association of Controlling Nutritional Status Score With Adverse Outcomes in Patients With Coronary Artery Disease: A Systematic Review and Meta-Analysis

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    Supplemental Material, sj-pdf-1-ang-10.1177_00033197221094409 for Association of Controlling Nutritional Status Score With Adverse Outcomes in Patients With Coronary Artery Disease: A Systematic Review and Meta-Analysis by Lijun Huang, Renliang He, Xiajun Sun, Jing Lv, and Shaoxi Chen in Angiology</p

    Angiotensin II induces soluble fms-Like tyrosine kinase-1 release via calcineurin signaling pathway in pregnancy

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    Maternal endothelial dysfunction in preeclampsia is associated with increased soluble fms-like tyrosine kinase-1 (sFlt-1), a circulating antagonist of vascular endothelial growth factor and placental growth factor. Angiotensin II (Ang II) is a potent vasoconstrictor that increases concomitant with sFlt-1 during pregnancy. Therefore, we speculated that Ang II may promote the expression of sFlt-1 in pregnancy. Here we report that infusion of Ang II significantly increases circulating levels of sFlt-1 in pregnant mice, thereby demonstrating that Ang II is a regulator of sFlt-1 secretion in vivo. Furthermore, Ang II stimulated sFlt-1 production in a dose- and time-dependent manner from human villous explants and cultured trophoblasts but not from endothelial cells, suggesting that trophoblasts are the primary source of sFlt-1 during pregnancy. As expected, Ang II-induced sFlt-1 secretion resulted in the inhibition of endothelial cell migration and in vitro tube formation. In vitro and in vivo studies with losartan, small interfering RNA specific for calcineurin and FK506 demonstrated that Ang II-mediated sFlt-1 release was via Ang II type 1 receptor activation and calcineurin signaling, respectively. These findings reveal a previously unrecognized regulatory role for Ang II on sFlt-1 expression in murine and human pregnancy and suggest that elevated sFlt-1 levels in preeclampsia may be caused by a dysregulation of the local renin/angiotensin system

    Inhomogeneous graph trend filtering via a l<sub>2,0</sub>-norm cardinality penalty

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    We study estimation of piecewise smooth signals over a graph. We propose a l2,0-norm penalized Graph Trend Filtering (GTF) model to estimate piecewise smooth graph signals that exhibit inhomogeneous levels of smoothness across the nodes. We prove that the proposed GTF model is simultaneously a k-means clustering on the signal over the nodes and a minimum graph cut on the edges of the graph, where the clustering and the cut share the same assignment matrix. We propose two methods to solve the proposed GTF model: a spectral decomposition method and a method based on simulated annealing. In the experiment on synthetic and real-world datasets, we show that the proposed GTF model has a better performances compared with existing approaches on the tasks of denoising, support recovery and semi-supervised classification. We also show that the proposed GTF model can be solved more efficiently than existing models for the dataset with a large edge set.</p

    Inhomogeneous graph trend filtering via A ℓ2,0-norm cardinality penalty

    No full text
    We study estimation of piecewise smooth signals over a graph. We propose a ℓ2,0-norm penalized Graph Trend Filtering (GTF) model to estimate piecewise smooth graph signals that exhibit inhomogeneous levels of smoothness across the nodes. We prove that the proposed GTF model is simultaneously a k-means clustering on the signal over the nodes and a minimum graph cut on the edges of the graph, where the clustering and the cut share the same assignment matrix. We propose two methods to solve the proposed GTF model: a spectral decomposition method and a method based on simulated annealing. In the experiment on synthetic and real-world datasets, we show that the proposed GTF model has a better performances compared with existing approaches on the tasks of denoising, support recovery and semi-supervised classification. We also show that the proposed GTF model can be solved more efficiently than existing models for the dataset with a large edge set

    sj-pdf-1-ang-10.1177_00033197221091315 – Supplemental Material for Relation Between New York Heart Association Functional Class and Remnant Cholesterol, and Non-high Density Lipoprotein Cholesterol in Coronary Heart Disease Patients With Type 2 Diabetes Mellitus

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    Supplemental Material, sj-pdf-1-ang-10.1177_00033197221091315 for Relation Between New York Heart Association Functional Class and Remnant Cholesterol, and Non-high Density Lipoprotein Cholesterol in Coronary Heart Disease Patients With Type 2 Diabetes Mellitus by Qi Cheng, Zhu Li, Xu Wang, Shuo Wang, Yijia Liu, Mengnan Huang, Yue Li, Xiaoxue Xue, Huaien Bu, Rongrong Yang, Yilan Xu, Lin Li, Shan Gao, Yanchao Zheng and Chunquan Yu in Angiology</p

    Inhomogeneous graph trend filtering via a l2,0 cardinality penalty

    No full text
    We study estimation of piecewise smooth signals over a graph. We propose a ℓ2,0-norm penalized Graph Trend Filtering (GTF) model to estimate piecewise smooth graph signals that exhibit inhomogeneous levels of smoothness across the nodes. We prove that the proposed GTF model is simultaneously a k-means clustering on the signal over the nodes and a minimum graph cut on the edges of the graph, where the clustering and the cut share the same assignment matrix. We propose two methods to solve the proposed GTF model: a spectral decomposition method and a method based on simulated annealing. In the experiment on synthetic and real-world datasets, we show that the proposed GTF model has a better performances compared with existing approaches on the tasks of denoising, support recovery and semi-supervised classification. We also show that the proposed GTF model can be solved more efficiently than existing models for the dataset with a large edge set

    Supplemental Material - China’s Low-Productivity Innovation Drive: Evidence From Patents

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    Supplemental Material for China’s Low-Productivity Innovation Drive: Evidence From Patents by Yuen Yuen Ang, Nan Jia, Yang Bo, and Kenneth Huang in Comparative Political Studies.</p

    Ang 1–7 decreased Ang II-stimulated ER stress.

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    <p>Representative blots and relative expression of ER stress proteins, phosphorylated eIF2α and ATF6 in (A) HUVECs and (C) in mouse aortas exposed to Ang II (0.5 μM, 24 hours) and co-treated with Ang 1–7 (1μM) and A779 (10 μM). (B) The mRNA expression of ER stress genes, CHOP, Grp78 and ATF4 in Ang II-treated HUVECs with or without Ang 1–7 and A779. Data are mean ± S.E.M (n = 5). <sup>*</sup>p<0.05 vs control; #p<0.05 vs Ang II, † p<0.05 vs Ang 1–7+Ang II.</p

    Li Ang, La femme du boucher, traduit par Alain Peyraube et Hua-Fang Vizcarra. 1992 Huang Fan, Le goût amer de la charité, traduit par Pierre Charau et Mathilde Chou. 1992

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    Curien Annie. Li Ang, La femme du boucher, traduit par Alain Peyraube et Hua-Fang Vizcarra. 1992 Huang Fan, Le goût amer de la charité, traduit par Pierre Charau et Mathilde Chou. 1992. In: Études chinoises, vol. 12, n°1, Printemps 1993. p. 214
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