15,071 research outputs found

    Table1_Bu-Fei-Huo-Xue capsule alleviates bleomycin-induced pulmonary fibrosis in mice through modulating gut microbiota.DOCX

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    Introduction: Bu-Fei-Huo-Xue capsule (BFHX) has been used to treat pulmonary fibrosis (PF) in clinic. However, the mechanism of Bu-Fei-Huo-Xue capsule on pulmonary fibrosis remains unclear. Recent studies have shown that the changes in gut microbiota were closely related to the progression of pulmonary fibrosis. Modulating gut microbiota provides new thoughts in the treatment of pulmonary fibrosis.Methods: In this study,a mouse model of pulmonary fibrosis was induced using bleomycin (BLM) and treated with Bu-Fei-Huo-Xue capsule. We firstly evaluated the therapeutic effects of Bu-Fei-Huo-Xue capsule on pulmonary fibrosis model mice. Besides,the anti-inflammatory and anti- oxidative effects of Bu-Fei-Huo-Xue capsule were evaluated. Furthermore, 16S rRNA sequencing was used to observe the changes in gut microbiota in pulmonary fibrosis model mice after Bu-Fei-Huo-Xue capsule treatment.Results: Our results showed that Bu-Fei-Huo-Xue capsule significantly reduced the collagen deposition in pulmonary fibrosis model mice. Bu-Fei-Huo-Xue capsule treatment also reduced the levels and mRNA expression of pro-inflammatory cytokines and inhibited the oxidative stress in lung. 16S rRNA sequencing showed that Bu-Fei-Huo-Xue capsule affected the diversity of gut microbiota and the relative abundances of gut microbiota such as Lactobacillus, Lachnospiraceae_NK4A136_group, and Romboutsia.Conclusion: Our study demonstrated the therapeutic effects of Bu-Fei-Huo-Xue capsule on pulmonary fibrosis. The mechanisms of Bu-Fei-Huo-Xue capsule on pulmonary fibrosis may be associated with regulating gut microbiota.</p

    A unified stochastic particle method based on the Bhatnagar-Gross-Krook model for polyatomic gases and its combination with DSMC

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    Simulating hypersonic flow around a space vehicle is challenging because of the multiscale and nonequilibrium nature inherent in these flows. To effectively deal with such flows, a novel particle particle hybrid scheme combining the stochastic particle Bhatnagar-Gross-Krook (BGK) method with Direct Simulation Monte Carlo (DSMC) was developed recently, but only for monatomic gases [Fei et. al., J. Comput. Phys. 2021]. Here this work is extended to the particle-particle hybrid method for polyatomic gases. In the near continuum regime, employing the Ellipsoidal Statistical BGK model proposed by Y. Dauvois, et. al. [Eur. J. Mech. B Fluids, 2021] with discrete levels of vibrational energy, the stochastic particle BGK method is first established following the idea of the unified stochastic particle BGK (USPBGK) scheme. In the fluid limit, it has been proven to be of second order temporal and spatial accuracy. Then, the USPBGK scheme with rotational and vibrational energies is combined with DSMC to construct a hybrid method for polyatomic gases. The present hybrid scheme is validated with numerical tests of homogenous relaxation, 1D shock structure and 2D hypersonic flows past a wedge and a cylinder. Compared to traditional stochastic particle methods, the proposed hybrid method can achieve higher accuracy at a much lower computational cost. Therefore, it is a more efficient tool to study multiscale hypersonic flows

    Coordination in a single-retailer two-supplier supply chain under random demand and random supply with disruption

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    This paper studies the coordination issue of a supply chain consisting of one retailer and two suppliers, a main supplier and a backup supplier. The main supplier’s yield is subject to disruption and the retailer faces a random demand. We determine the retailer’s optimal ordering policy and the main supplier’s production quantity that maximize expected profit of the centralized supply chain. We also analyze the decentralized scenario, and a combination of overproduction risk sharing and buy-back contracts with a side payment from/to the backup supplier is provided to coordinate the supply chain. Numerical examples are given to gain some qualitative insights.Fei Hu, Cheng-Chew Lim, Zudi Lu, and Xiaochen Su

    sj-docx-1-cnr-10.1177_10547738211060937 – Supplemental material for Relationship Between Physical Fitness, Anthropometric Measurement, and Bone Health in Adult Men

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    Supplemental material, sj-docx-1-cnr-10.1177_10547738211060937 for Relationship Between Physical Fitness, Anthropometric Measurement, and Bone Health in Adult Men by Xiaoguang Zhao and Fei Hu in Clinical Nursing Research</p

    External Diaphragmatic Pacing Combined with Hu Xi Jian Fei Gong inthe Treatment of Pulmonary Dysfunction after Stroke

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    Objective To investigate the clinical effect of external diaphragmatic pacing(EDP) combined with Hu Xi Jian Fei Gong in the treatment of pulmonary dysfunction in stroke patients. Methods From July 2020 to July 2022, 162 stroke patients in Shanghai Tongren Hospital and Yueyang Hospital of Integrated Traditional Chinese and Western Medicine were randomly divided into a control group and an observation group, with 81 patients in each group.Both group received conventional rehabilitation and EDP, and the observation group additionally received Hu Xi Jian Fei Gong.Forced vital capacity(FVC), forced expiratory volume in 1 second(FEV1), peak expiratory flow(PEF), diaphragmatic mobility, end-expiratory diaphragmatic thickness, and end-inspiratory diaphragmatic thickness were compared between the two groups before treatment and after 4 weeks of treatment.The activity of daily living(ADL) of 72 patients admitted to Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine were compared before treatment, after 4 weeks of treatment and 12 weeks after the end of treatment. Results After treatment, FVC, FEV1, PEF, end-expiratory diaphragmatic thickness and end-inspiratory diaphragmatic thickness in the two groups were higher than those before treatment(P<0.05), and the observation group was higher than the control group(P<0.05).After 4 weeks of treatment and 12 weeks after the end of treatment, the ADL scores of 72 patients were higher than those before treatment(P<0.05), and the observation group was higher than the control group(P<0.05). Conclusion EDP combined with Hu Xi Jian Fei Gong training can better improve the pulmonary function of patients after stroke

    Fei-yen wai-zhuan the true era of its birth and investigation of its author

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    Fei-yen wai-zhuan 飛燕外傳 (The Unofficial Biography of [Zhao] Fei-yen) is one of the classical-language fictions in traditional China, describing the famous romance between Emperor Cheng-di 成帝 and Zhao Fei-yen 趙飛燕 sisters in the Former Han Dynasty. The author is attributed with Ling Xüan 伶玄, who definitely had confessed that he was living with the Former Han Dynasty in his brief autobiography. However, it was too suspicious to believe, from the beginning of its appearance in the Southern Song Dynasty, scholars have been puzzled to determine the true era of its birth. Through their discussions, now it is widely accepted that Fei-yen wai-zhuan was born during the Six Dynasties, not in the Tang Dynasty, though it is still lacking in conclusive evidence. But some insist that it could be compared with the great masterpieces of Tang-tales, like Ying-ying zhuan 鶯鶯傳, Li Wa zhuan 李娃傳, Huo Xiao-yü zhuan 霍小玉傳, which belonged to the Tang Dynasty. Then should we say that Fei-yen wai-zhuan was a premature masterpiece? It still remains a great mystery to all, including its author Ling Xüan himself. This study, paying attention to the text itself, proves this tale should belong to the Tang Dynasty. Its main keywords are two, Zhen-la 眞臘 and Qi-chu Ling-hua jing 七出菱花鏡 (Water-chestnut flower shaped bronze mirror, circled by seven petals). The former, used first in the historical records in China was in the Sui Dynasty Da-ye 大業 12years(616), and the latter one likely appeared after reign of Empress Wu(690--705). These facts simply tell us Fei-yen wai-zhuan was born in the Tang Dynasty. The true author of this tale is Niu Seng-ru 牛僧孺, a famous prime minister of late Tang and was also a well-known writer of Tang-tales, who authored Xüan-guai lu 玄怪錄. We could know the close affinities between Fei-yen wai-zhuan and Xüan-guai lu. As a drafted scholar-official, all of Niu's life had been under the strife in bureaucracy with the factional parties at that time. Once the opposition party blamed Niu for violating his majesty, to write the tale Zhou Qin xing-ji 周秦行記 named Niu Seng-ru. Though its writer was anonymous, Niu was nearly accused of injury to the majesy (Lèse majesté). I contend Niu decided to write Fei-yen wai-zhuan under a pseudonym to make counterattack against a recreant writer in the same manner and to regain true pride for himself

    Atympanophrys Tian & Hu 1983

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    III. Genus Atympanophrys Tian & Hu, 1983 Suggested common name: Hidden-tympanum horned toads (in English) / &Lmidot;HDzfl (in Chinese) Four species: Atympanophrys shapingensis (Liu, 1950) (type species); Atympanophrys gigantica (Liu, Hu & Yang, 1960); Atympanophrys nankiangensis (Liu & Hu, 1966); Atympanophrys wawuensis (Fei, Jiang & Zheng, 2001).Published as part of Qi, Shuo, Lyu, Zhi-Tong, Wang, Jian, Mo, Yun-Ming, Zeng, Zhao-Chi, Zeng, Yang-Jin, Dai, Ke-Yuan, Li, Yuan-Qiu, Grismer, L. Lee & Wang, Ying-Yong, 2021, Three new species of the genus Boulenophrys (Anura, Megophryidae) from southern China, pp. 401-438 in Zootaxa 5072 (5) on page 430, DOI: 10.11646/zootaxa.5072.5.1, http://zenodo.org/record/574897

    Petrocosmea dejiangensis (Gesneriaceae), a new species from Guizhou, China

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    Xu, Jian, Li, Sa, Tang, Sheng-Hu, Ren, Qi-Fei (2022): Petrocosmea dejiangensis (Gesneriaceae), a new species from Guizhou, China. Phytotaxa 539 (1): 17-23, DOI: 10.11646/phytotaxa.539.1.2, URL: http://dx.doi.org/10.11646/phytotaxa.539.1.

    Cynanchum neoleucanthum subsp. elongatum Zhang & Onjalalaina & Liao & Hu 2023, comb. nov.

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    &lt;p&gt; &lt;i&gt;Cynanchum neoleucanthum&lt;/i&gt; subsp. &lt;i&gt;elongatum&lt;/i&gt; (Liede) Cai F. Zhang, G.W. Hu &amp; Q.F. Wang, &lt;i&gt;comb. nov.&lt;/i&gt;&lt;/p&gt; &lt;p&gt; &lt;b&gt;Basionym:&lt;/b&gt; &lt;i&gt;Cynanchum leucanthum&lt;/i&gt; subsp. &lt;i&gt;elongatum&lt;/i&gt; Liede (1993: 445).&lt;/p&gt; &lt;p&gt; TYPE:&mdash; MADAGASCAR. Antsiranana, Massif de Marivorahona au Sud-Ouest de Manambato (haute Mahavavy du Nord, district d&rsquo;Ambilob&eacute;), 1750 m, 18&ndash;26 Mar. 1951 (fl.), &lt;i&gt;H. Humbert &amp; R. Capuron&lt;/i&gt; 25670 (holotype, P [P00057353]; isotypes, P [P00442682, P00057354]).&lt;/p&gt;Published as part of &lt;i&gt;Zhang, Cai-Fei, Onjalalaina, Uy. E., Liao, Miao &amp; Hu, Guang-Wan, 2023, Cynanchum neoleucanthum (Apocynaceae), a replacement name for the later illegitimate homonym Cynanchum leucanthum (K. Schum.) K. Schum, pp. 297-298 in Phytotaxa 597 (4)&lt;/i&gt; on page 298, DOI: 10.11646/phytotaxa.597.4.5, &lt;a href="http://zenodo.org/record/7958710"&gt;http://zenodo.org/record/7958710&lt;/a&gt

    FIGURE 2 in Petrocosmea dejiangensis (Gesneriaceae), a new species from Guizhou, China

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    FIGURE 2. Petrocosmea martini (H.Lév.) H.Lév. A habitat B flowering plant C petioles, rhizome, and fibrous roots D adaxial surface of leaf blade E abaxial surface of leaf blade F cyme and bract (inset) G flower in front view H flower in side view I flower in top view J opened corolla, showing stamens and spots K stamens L pistil and stigma (inset). (Photographs by Sheng-Hu Tang).Published as part of Xu, Jian, Li, Sa, Tang, Sheng-Hu & Ren, Qi-Fei, 2022, Petrocosmea dejiangensis (Gesneriaceae), a new species from Guizhou, China, pp. 17-23 in Phytotaxa 539 (1) on page 20, DOI: 10.11646/phytotaxa.539.1.2, http://zenodo.org/record/634589
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