111 research outputs found
Fig. 6 in Armochaetoglasins A-I: Cytochalasan alkaloids from fermentation broth of Chaetomium globosum TW1-1 by feeding L-tyrosine
No full textFig. 6. Experimental ECD spectra (in MeOH) of compounds 1–5 and 7–9.Published as part of <i>Gao, Weixi, Sun, Weiguang, Li, Fengli, Chai, Chenwei, He, Yan, Wang, Jianping, Xue, Yongbo, Chen, Chunmei, Zhu, Hucheng, Hu, Zhengxi & Zhang, Yonghui, 2018, Armochaetoglasins A-I: Cytochalasan alkaloids from fermentation broth of Chaetomium globosum TW1-1 by feeding L-tyrosine, pp. 106-115 in Phytochemistry 156</i> on page 112, DOI: 10.1016/j.phytochem.2018.09.004, <a href="http://zenodo.org/record/10484462">http://zenodo.org/record/10484462</a>
後漢光武帝と儒教的讖緯―莽新末後漢初の政治情勢から―
No full textAlong with development of the study of the Confucian classics (jingxue 經學) during the Han Period, there also appeared a related strain of mystic doctrine (chenwei 讖緯), related to the power of the emperors. The research to date on the use of chenwei-related works has indicated the possibility that although the writings on divination (tuchen 圖讖) done at the time of the enthronement of Later Han Emperor Guangwu (Guangwudi 光武帝; r. 25–57 CE) had no ideational connection to either Confucius or the Confucian classics, by the time of the fengshan 封禪 festivals of heaven and earth at Mt. Taishan 泰山, such prophetic writing was being influenced by Confucian ideas. The present article follows this research in considering exactly how Emperor Guangwu came to deal with chenwei works in connection with Confucian thought.
To begin with, despite the fact that the theory that Confucius had written chenwei books to testify to the establishment and continued existence of the Han dynasty (Kong Qiu Mijing 孔丘秘經 Theory) had already appeared during the last years of the Xin Dynasty, the influence of Confucian chenwei thought was no widespread; and even after the uprising and enthronement of Emperor Guangwu, little interest was directed at the connection of chenwei to Confucianism. Rather, it was a time when the Emperor regarded chenwei as being effective in more concrete matters connected to rural life, the conquest of Hebei, etc.
It was not until around the 6th year of Jianwu Era (30 CE) that Gongsun Shu 公孫述, the independent warlord of the Sichuan region, began operations to incite people by spreading the word of Confucian chenwei throughout Zhongyuan 中原. Meanwhile, beginning in the previous year, Emperor Guangwu had initiated various programs aimed at stabilizing the social crisis and chaos in the midst of military conflict through the introduction of Confucian ideas. Both movements were attempts to appeal to, agitate among and win the hearts of the people of Zhongyuan, who were by no means steadfast in loyalty to the Emperor Guangwu’s regime, by appealing to them, even if symbolically, with the then widely shared authority, i.e. Confucian ideas.
The author concludes that the preconditions for these efforts, i.e. the penetration of Confucianism into Chinese society, led to the utilization of Confucian chenwei by Emperor Guangwu, through the political tensions at the beginning of the Later Han Period
Emperor Guangwu and Mystic Confucian Doctorine as Seen from the Political Situation of the Late Xin–Early Later Han Dynasty Eras
No full textAlong with development of the study of the Confucian classics (jingxue 經學) during the Han Period, there also appeared a related strain of mystic doctrine (chenwei 讖緯), related to the power of the emperors. The research to date on the use of chenwei-related works has indicated the possibility that although the writings on divination (tuchen 圖讖) done at the time of the enthronement of Later Han Emperor Guangwu (Guangwudi 光武帝; r. 25–57 CE) had no ideational connection to either Confucius or the Confucian classics, by the time of the fengshan 封禪 festivals of heaven and earth at Mt. Taishan 泰山, such prophetic writing was being influenced by Confucian ideas. The present article follows this research in considering exactly how Emperor Guangwu came to deal with chenwei works in connection with Confucian thought.
To begin with, despite the fact that the theory that Confucius had written chenwei books to testify to the establishment and continued existence of the Han dynasty (Kong Qiu Mijing 孔丘秘經 Theory) had already appeared during the last years of the Xin Dynasty, the influence of Confucian chenwei thought was no widespread; and even after the uprising and enthronement of Emperor Guangwu, little interest was directed at the connection of chenwei to Confucianism. Rather, it was a time when the Emperor regarded chenwei as being effective in more concrete matters connected to rural life, the conquest of Hebei, etc.
It was not until around the 6th year of Jianwu Era (30 CE) that Gongsun Shu 公孫述, the independent warlord of the Sichuan region, began operations to incite people by spreading the word of Confucian chenwei throughout Zhongyuan 中原. Meanwhile, beginning in the previous year, Emperor Guangwu had initiated various programs aimed at stabilizing the social crisis and chaos in the midst of military conflict through the introduction of Confucian ideas. Both movements were attempts to appeal to, agitate among and win the hearts of the people of Zhongyuan, who were by no means steadfast in loyalty to the Emperor Guangwu’s regime, by appealing to them, even if symbolically, with the then widely shared authority, i.e. Confucian ideas.
The author concludes that the preconditions for these efforts, i.e. the penetration of Confucianism into Chinese society, led to the utilization of Confucian chenwei by Emperor Guangwu, through the political tensions at the beginning of the Later Han Period.journal articl
GE-mini: a mobile APP for large-scale gene expression visualization
No full textThe Cancer Genome Atlas (TCGA) and Genotype-Tissue Expression (GTEx) projects produced large-scale RNA sequencing data, which provides an opportunity for performing integrated expression analysis for all genes across tens of thousands of tumor and normal tissue specimens. Rapid access to and easy visualization of such valuable data could facilitate research in a wide biological area. Here, we present the GE-mini APP for smart phones, a mobile visualization tool for integrated gene expression data based on both TCGA and GTEx. This gene-centric expression viewer provides a convenient method for displaying expression profiles of all available tumor and tissue types, while allowing drilling down to detailed views for specific tissue types.National Natural Science Foundation of China [31530036, 81573022]; Key Technologies RD Program [2016YFC0900100]SCI(E)ARTICLE6941-9433
Integrating Customized Geographical Data Into Google Earth
No full textThe objective of this project is to develop an interactive WebGIS for North Atlantic scholars by providing geographic data services of converting, downloading, sharing, visualizing and analyzing data. A Web-based application system is produced to allow the North Atlantic scholars to upload their customized geographic data (in shapefile or CSV file format) through a simple web surface. Uploaded data will be converted into KML as well as shapefiles or CSV files, and the users will be able to download these files and then visualize their data in Google Earth. Various languages and programmes were used in this project, including Oracle RDBMS, SQL, Perl, HTML and KML. The Web-based tool provides users with limited GIS knowledge the ability to use geobrowsers to analyze customized geodata from different formats
Masculinity, Sociosexual Hierarchy, and the Lives of Gay, Bisexual, Queer (GBQ+) Community in Singapore
No full textSexuelle Orientierung und geschlechtsspezifische Normen sind eng miteinander verwoben und werden von kulturellen, sozialen und politischen Strukturen beeinflusst. Diese prägen die soziosexuellen Hierarchien,
die der Einzelne auf der Grundlage seiner sexuellen und geschlechtlichen Identität von klein auf erfährt, und wirken sich auf die Ergebnisse des Einzelnen in unterschiedlichen kulturellen Kontexten aus. Singapur stellt einen einzigartigen Fall dar, in dem euroamerikanische Ansätze mit seinen asiatischen kulturellen Wurzeln zusammenfließen. Ausgehend von dem Singapurer Fall adressiert diese Studie die bestehende Lücke im Verständnis darüber, wie soziosexuelle Hierarchien die Erfahrungen von schwulen, bisexuellen und queeren (GBQ+) Männern beeinflussen. In dieser umfassenden Studie über die gelebten Erfahrungen von GBQ+-Männern in Singapur, wurden die Interviews von neun Personen systematisch analysiert, um zu verstehen, wie die soziosexuelle Hierarchie in Singapur eschlechtsspezifische Normen beeinflusst und sich auf ihr Leben auswirkt. Ausgehend von der Theorie der prekären Männlichkeit deuten die Ergebnisse darauf hin, dass Männer aus dem gesamten Spektrum der sexuellen Orientierung GBQ+-Männer mit dem Ziel schikanieren, in der soziosexuellen Hierarchie aufzusteigen. Internalisierten Männlichkeitserwartungen führen bei GBQ+ Männern zu Scham und Selbstkontrolle, was sich auf ihre psychische Gesundheit auswirkt. Über die Selbstkontrolle hinaus betreiben GBQ+ Männer auch Community Policing, um andere GBQ+ Männer zu bestrafen, die die Männlichkeitsstandards nicht erfüllen. Trotz der Stigmatisierung widersetzten sich einige GBQ+ Community-Mitglieder der soziosexuellen Hierarchie, um ihr authentisches Selbst zu leben, was ihnen ein Gefühl der Authentizität vermittelte.Schlagworte: Geschlechtsspezifische Normen, soziosexuelle Hierarchie, Theorie der Prekären Männlichkeit, schwule
bisexuelle und queere MännerSexual orientation and gendered norms are deeply intertwined and influenced by cultural, social, and political structures – these shape the sociosexual hierarchies that one experiences based on their sexual and gender identities from an early age, and impact individuals’ outcomes in different cultural contexts. Singapore presents a unique case where it combines Euroamerican approaches with its Asian cultural roots. In Singapore, there remains a gap in the understanding of how sociosexual hierarchies influence the experience of gay, bisexual, and queer (GBQ+) men in Singapore. Derived from a broader study investigating the lived experiences of GBQ+ men, this study thematically analysed the interviews of nine GBQ+ men to understand how Singapore’s sociosexual hierarchy influences gendered norms and impacts their lives. Drawing from the lens of the Precarious Manhood theory, the findings suggest that men across the sexual orientation spectrum victimise GBQ+ men with the goal of climbing up the sociosexual hierarchy. Expectations of masculinity created internalised shame and self-policing for GBQ+ men, impacting their mental health outcomes. Beyond the self, GBQ+ men also engage in community policing to punish other GBQ+ men who fail to meet masculinity standards. Despite the stigma, some GBQ+ community members resisted the sociosexual hierarchy to live their authentic selves, which allowed them a sense of authenticity. With a better appreciation of the processes of the sociosexual hierarchy, we recommend adopting strategies that conscientiously promote inclusivity for GBQ+ men in Singapore, and challenge masculinity norms through interventions that reach men across the sexuality spectrum.Keywords: Gendered norms, sociosexual hierarchy, Precarious Manhood Theory, gay bisexual and queer men, Singapor
EchoArtLink:Enhancing Social Connectedness Between Parents and Children Living Apart Through Digital Sound Visualization
No full textMore and more family members experience geographic separation over long distances due to global migration and the pursuit of better education and work opportunities. Maintaining social connectedness between children and parents who live apart becomes a critical challenge. This study introduces EchoArtLink, a system that collects sound data and transforms them into digital art displayed on family picture frames. This design leverages sound visualization technology to enhance social connectedness among family members living apart. This system offers two methods of sound visualization: visualizing activities recognized from sounds (Method activities) and visualizing the sound features directly without recognizing activities (Method features). This study conducted a mixed-methods experiment involving 10 participants and their geographically separated parents to explore how two visualization methods affect social connectedness differently between parents and children living apart. The results revealed that the participants gained higher levels of connectedness after experiencing both visualization methods. This study contributes to the field of social connectedness by offering a novel system and valuable insights into the role of sound visualization in long-distance family communication.</p
Exploring constraints on dialogic interaction in immersive environments arising from COVID-19 protocols
No full textThe open access publication is available at: https://ieeexplore.ieee.org/document/9815922This paper describes an independent research study undertaken by a high school student under the mentorship of a Research Scientist at the National Institute of Education, Singapore. It explores how dialogic interactions on a given Mathematical topic, decimals, can be constrained in the remote learning platform Zoom. This research utilises Laurillard’s Conversational Framework for a small-scale intervention of two virtual learning sessions in Minecraft Education Edition, focusing on the decimal learning for primary school students. The study found that the overlapping of the immersive learning environment and remote learning platform engenders miscommunications, disorientation, and cognitive dissonance amongst both the teacher and the student, prolonging the discursive and adaptive phases in the dialogic interactions
Recent trends in electronic skin for transdermal drug delivery
No full textThis paper presents an in-depth discussion of the development of electronic skin (e-skin) devices for transdermal drug delivery (TDD) for skin health management. E-skin devices, grounded in flexible conductive polymers, demonstrate immense potential as a versatile platform for TDD due to the adaptable properties factors. The integration of sensors and electronic components into e-skin devices seamlessly allows for real-time monitoring of skin health parameters, such as temperature, hydration, and pH levels. Additionally, e-skin devices can also realize the prospect of targeted and controlled drug delivery through the utilization of iontophoresis. This paper explores the current state-of-the-art in e-skin technology, emphasizing its applications in TDD and skin disease management. Furthermore, the paper outlines the prospective directions and prevailing challenges in this rapidly evolving domain
Effect of tool Inclination Angle on the Elastic Deformation of Thin-walled Parts in Multi-axis Ball-end Milling
No full textAbstractThin-walled freeform surface parts are widely used in many fields, such as aerospace, automotive, etc. However, it is difficult to produce high quality thin-walled freeform parts in Numerical Controlled(NC) machining due to bending and twisting deformations induced by cutting forces. To overcome this problem, key issues are focused on twofold. First, the relationship between the milling force and the tool inclination angle in ball-end milling was established by using the theoretical and experimental methods. Second, the influence of tool inclination angle on the elastic deformation of thin-walled parts was analyzed by the finite element method. Finally, verification experiment was carried out in a 4-axis CNC machine tool, and the deformation values of the stainless steel test workpieces were measured by a coordinate measurement machine(CMM). The results show that when the tool inclination angles are 15° or 45°, both the milling force and the deformation of the test workpieces are the smallest
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