2,095 research outputs found
Optimization of the solubilization and renaturation of fish growth hormone produced by Escherichia coli.
No full textEscherichia coli-produced fish growth hormone as a feed additive to enhance the growth of juvenile black seabream (Acanthopagrus schlegeli).
No full textNon-alloy Mg anode for Ni-MH batteries: Multiple approaches towards a stable cycling performance
No full textMg attracts much research interest as anode material for Ni-MH batteries thanks to its lightweight, cost-effectiveness and high theoretical capacity (2200 mA h g−1). However, its practical application is tremendously challenged by the poor hydrogen sorption kinetics, passivation from aggressive aqueous electrolytes, and insulating nature of MgH2. Mg-based alloys exhibit enhanced hydrogen sorption kinetics and electrical conductivity, but significant amount of costly transition metal elements are required. In this work, we have, for the first time, utilized non-alloyed but catalyzed Mg as anode for Ni-MH batteries. 5 mol.% TiF3 was added to nanosized Mg for accelerating the hydrogen sorption kinetics. Several strategies for preventing the problematic passivation of Mg have been studied, including protective encapsulation of the electrode and utilizing room-temperature/high-temperature ionic liquids and an alkaline polymer membrane as working electrolyte. Promising electrochemical performance has been achieved in this Mg–TiF3 composite anode based Ni-MH batteries with room for further improvements.</p
Assessing risk of self-harm in acute paediatric settings: A multicentre exploratory evaluation of the CYP-MH SAPhE instrument
Full text linkOBJECTIVE: To psychometrically assess the Children and Young People-Mental Health Self-harm Assessment in Paediatric healthcare Environments (CYP-MH SAPhE) instrument for the identification of immediate risk of self-harm in CYP, aged 10-19 years, in acute paediatric wards or emergency departments., DESIGN: The CYP-MH SAPhE Instrument was developed through a robust scoping review and Delphi consensus with 30 clinicians/topic experts. To evaluate the psychometric properties, a multicentre exploratory study was conducted., SETTING: Three acute hospitals in the UK., PARTICIPANTS: 163 CYP presenting at acute hospital settings with primary mental health (cases) or physical health (non-cases) conditions., PRIMARY AND SECONDARY OUTCOME MEASURES: Psychometric properties of the CYP-MH SAPhE instrument were evaluated through Principle Axis Factoring (PAF) with Oblimin (Kaiser normalisation) alongside measures of internal consistency (Cronbach's alpha), convergent, discriminant and face validity., RESULTS: PAF of the dichotomous items (n=9) loaded onto three factors (1) behaviours and intentions; (2) suicidality and (3) self-harm. Factors 1 (Cronbach's alpha=0.960) and 3 (Cronbach's alpha=1) had high internal consistency. There was: good level of agreement between raters (kappa=0.65); a moderately positive correlation between the CYP-MH SAPhE instrument and the Columbia-Suicide Severity Rating Scale; and discrimination between cases and non-cases across the three factors (factor 1: m=88 vs 70; factor 2: m=102 vs 70; factor 3: m=104 vs 68). Assessment of face validity resulted in six items being removed, culminating in an eight question, rapid assessment instrument., CONCLUSIONS: The results support the CYP-MH SAPhE Tool as a potentially reliable and valid instrument to identify immediate risk of self-harm in CYP presenting to acute paediatric healthcare environments, which is a burgeoning and significant global health issue. Copyright © Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.https://dx.doi.org/10.1136/bmjopen-2020-04376
The times; or, the age of ruin. A poem. [electronic resource] : By the author of "A poetical and complimentary epistle to R. Brothers the prophet, and N. B. Halhed, Esq;" &c.
No full textPublication date from MH-H.Electronic reproduction.English Short Title Catalog,Reproduction of original from Harvard University Houghton Library
[The] lady's watch. [electronic resource] : By the author of The prude.
No full textVerse - "A fair one sought the silent poplar shade".'The prude, a tale.' was first published in Dublin in 1722.MH-H copy may be cropped at head, affecting first word of titleFoxon,Electronic reproduction.English Short Title Catalog,Reproduction of original from Harvard University Houghton Library
Between Mother and Son: Preparation of the assambly MH+-
No full textEl presente informe recopila los detalles y el proceso creativo de la obra de danza MH+-, donde se reunieron los saberes académicos en términos prácticos, teóricos y experienciales, apropiados por el estudiante y autor de la obra en mención y este texto, Ricardo Nieto Ortíz. En esta obra se tomó como inspiración temática la relación personal de dicho estudiante y su madre, desde el momento en que este se identificó frente a ella como un hombre homosexual. El proceso de creación se llevó a cabo a través de un laboratorio de investigación creación con seis intérpretes creadores, incluido Ricardo Nieto, durante seis meses, con cuatro etapas de desarrollo utilizando herramientas como la improvisación, la creación de personajes y la ejercitación de los imaginarios que nutren los procesos creativos de los intérpretes.This report compiles the details and the creative process of the dance work MH+-, where the academic knowledge in practical, theoretical and experiential terms was gathered, appropriated by the student and author of the work in question and this text, Ricardo Nieto Ortiz. In this work, the personal relationship of this student and his mother was taken as thematic inspiration, from the moment he identified himself in front of her as a homosexual man. The creation process was carried out through a creation research laboratory with six creative interpreters, including Ricardo Nieto, for six months, with four stages of development using tools such as improvisation, the creation of characters and the exercise of the imaginaries that nourish the creative processes of the performers
Systematic reviews with language restrictions and no author contact have lower overall credibility: a methodology study
No full textZhen Wang,1–3 Juan P Brito,4 Apostolos Tsapas,5 Marcio L Griebeler,4 Fares Alahdab,1,3 Mohammad Hassan Murad,1,3,61Robert D and Patricia E Kern Center for the Science of Health Care Delivery, 2Division of Health Care Policy and Research, Department of Health Sciences Research, 3Knowledge and Evaluation Research Unit, 4Division of Endocrinology, Diabetes, Metabolism, and Nutrition, Mayo Clinic, Rochester, MN, USA; 5Aristotle University of Thessaloniki, Thessaloniki, Greece; 6Division of Preventive, Occupational and Aerospace Medicine, Mayo Clinic, Rochester, MN, USABackground: High-quality systematic reviews (SRs) require rigorous approaches to identify, appraise, select, and synthesize research evidence relevant to a specific question. In this study, we evaluated the association between two steps in the conduct of an SR – restricting the search to English, and author contact for missing data – and the overall credibility of a SR.Methods: All SRs cited by the Endocrine Society's Clinical Practice Guidelines published from October 2006 through January 2012 were included. The main outcome was the overall A Measurement Tool to Assess Systematic Reviews (AMSTAR) score, as a surrogate of SR credibility. Nonparametric Kruskal–Wallis tests and multivariable linear regression models were used to investigate the association between language restriction, author contact for missing data, and the overall AMSTAR score.Results: In all, 69 SRs were included in the analysis. Only 31 SRs (45%) reported searching non-English literature, with an average AMSTAR score of 7.90 (standard deviation [SD] =1.64). SRs that reported language restriction received significantly lower AMSTAR scores (mean =5.25, SD =2.32) (P<0.001). Only 30 SRs (43%) reported contacting authors for missing data, and these received, on average, 2.59 more AMSTAR points (SD =1.95) than those who did not (P<0.001). In multivariable analyses, AMSTAR score was significantly correlated with language restriction (beta =-1.31, 95% confidence interval [CI]: -2.62, -0.01, P=0.05) and author contact for missing data (beta =2.16, 95% CI: 0.91, 3.41, P=0.001). However, after adjusting for compliance with reporting guidelines, language restriction was no longer significantly associated with the AMSTAR score.Conclusion: Fewer than half of the SRs conducted to support the clinical practice guidelines we examined reported contacting study authors or searched non–English literature. SRs that did not conduct these two steps had lower quality scores, suggesting the importance of these two steps for overall SR credibility.Keywords: evidence-based medicine, research design, validity, quality of evidenc
Strategies for implementing group mental health interventions in a VA community living center [online ahead of print]
No full textObjectives: Group mental health interventions are difficult to implement into rehabilitation facilities, but no one has studied the specific barriers. This mixed-methods project systematically examined the implementation of a mental health (MH) group intervention in a VA community living center (CLC) for residents on subacute rehabilitation units, using the Promoting Action on Research Implementation in Health Services (PARIHS) implementation framework.Methods: We implemented a group MH intervention, tracking team referrals, attendance rates, and reasons for declining to participate. We conducted qualitative interviews with attendees.Results: Individual barriers to attendance included acute illness (n = 67, 20%), attitudes toward MH (n = 50; 15%), and perceived busyness (n = 19; 6%). Facility barriers included competing appointments (n = 69; 21%). Interviews demonstrated challenges to implementation, including stigma toward mental health (Theme: Challenges and Supports to Implementation). Attendees found the group relatable, and noted that both positive and negative group dynamics contributed to their experience (Themes: Content Relevance and Group Dynamics).Conclusions: The results provide insight into implementing a group MH treatment into the CLC setting, with implications for the MH care of older adults residing in CLCs.Clinical Implications: 1) Group leaders should consider matching attendees for ability levels (physical or cognitive). 2) At the facility level, leaders may take steps to address stigma toward MH by adopting approaches (e.g., music) or framing MH issues (e.g., use of language) in a way that is approachable. 3) Modifiable barriers at the individual and facility level could be addressed to encourage ease of implementation
Flight testing Flow Diverting Devices on an OH-58A+ for applications to an MH-6 Helicopter
Full text linkThis study investigates the use of Flow Diverting Devices to reduce passenger fatigue and parasite drag (specifically equivalent flat plate drag) for the 160*\u27* Special Operations Aviation Regiment MH-6 Helicopters. Due to cost, scheduling, and airworthiness release (AWR\u27s) issues this manuscript focuses on the actual flight test data of a similar helicopter, the OH-58A+. The flight-testing investigated the level flight performance, and handling qualities with doors removed, with and without the Flow Diverters installed. Consideration was also given in the design to discover ways of minimizing the airflow on the external passengers (amount of deflection), changes in noise level, and to the reduction in the field of view measured from the Design Eye Position. The baseline aircraft (with doors removed) was tested against 3 different types of Flow Diverting Devices (6 inch Sawtooth, 6 inch Flat Plate with Vortex Generators installed, and 8 inch Flat Plate with Vortex Generators installed).
It was determined that the airflow can be deflected away from the passengers a maximum of 16 inches with no adverse impact on handling qualities. This is important for several reasons:
1. Possible increase in performance.
2. Passenger comfort.
3. Mission envelope expansion.
This mission envelope expansion would include the ability to fly in colder temperatures, feasible to fly in precipitation, as well as possibly having the ability to maintain faster enroute speeds without causing undue fatigue on the passengers. This deflection was achieved with an average increase of 4.0 square feet of equivalent flat plate drag. This is much less than the effect flat plate drag on the MH-6 due to passengers and equipment installed for the mission. Additionally, during the flight testing it was noted that there were no detectable changes to the handling qualities or the noise level inside the test aircraft.
Hence, the author concluded that the 8 inch Flat Plate, with Vortex Generators, Flow Diverting Device will successfully divert the airflow around the upper body of the external passengers thus reducing passenger fatigue and increasing their safety during flight. It is reasonable to assume that the MH-6 helicopter will realize a performance enhancement during flight in high drag configurations (with external passengers). Additionally, it is also possible that the MH-6 in the baseline configuration (doors off, external passenger system installed) could realize a slight performance increase.
The author made the following recommendations;
1. Develop a set of flow diverters specifically for the MH-6.
a. 8 Flat Plate with Vortex Generators.
b. The angle should be between 40° and 50°.
c. The Flow Diverter should be capable of 2 positions, full open (maximum deflection) and fully closed (no Deflection). However, if there is a performance increase with the flow diverters installed over the baseline MH-6 there would be little reason to use the fully closed position.
2. Conduct Flight Tests with an MH-6 in its typical mission configuration.
a. These tests should include flights with and without external ballast.
b. At least two of the flight tests should be with an FTE as an external passenger. For a qualitative comparison evaluation one flight test should be with no deflection and the other with maximum deflection.
3. Recommend that all doors are removed at all times with Flow Diverters installed.
4. Recommend the use of the Smoke Generator System with a greater volume of smoke. This can be done by either a specialized smoke canister or with a portable smoke generator
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