52,923 research outputs found
Tissue-specific expression and chromosome assignment of genes specifying two isoforms of subunit VIIa of human cytochrome c oxidase
No full textSubunit VIIa of mammalian cytochrome c oxidase (COX; EC 1.9.3.1) exists in at least two isoforms, one present in all tissue types ('liver' isoform; COX VIIa-L) and the other specific for cardiac and skeletal muscle (COX VIIa-M). We have isolated a full-length cDNA encoding human COX VIIa-M. The deduced polypeptide represents the human ortholog of COX VIIa-M, as it shares 78% identity with bovine COX VIIa-M, but only 63% identity with human COX VIIa-L. Northern-blot analysis of primate tissues demonstrated that COXVIIa-M mRNA is present only in muscle tissues; in contrast, the COXVIIa-L mRNA is present in both muscle and nonmuscle tissues. Southern-blot hybridization of human-rodent cell hybrid genomic DNA indicates that the COXVHa-M gene maps to a single locus on chromosome 19, designated COX7AM. In contrast, COXVIIa-L cDNA probes hybridized to fragments from two COX7AL loci, on chromosomes 4 and 14. © 1992
Comments on "Maximum mechanical efficiency infinitely variable transmissions"
No full textComments on "Maximum mechanical efficiency infinitely variable transmissions", H. S. Yan and L. C. Hsieh. Mechanism and Machine Theory, Vol. 29, No. 5, pp. 777-784 (1994
Effect of Prostaglandin E1 Analogue, Alprostadil, against the Hepatic Ischemia-Reperfusion Injury in Rats.
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Molecular cloning and sequence analysis of stearoyl-CoA desaturase in milkfish, Chanos chanos
No full textFatty acid desaturation and stearoyl-CoA desaturase expression in the hepatic microsomes of Milkfish, Chanos chanos, under cold shock
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