6,444 research outputs found

    Joseph Bimeler book order to Peter Kaufmann, February 14, 1845

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    Order of two dozen German A.B.C. books (primers) by J.M. Bimeler (by Lewis F. Birk) from Peter Kaufmann. Led by Joseph Bimeler (sometimes spelled Bäumeler) in 1817, a group of Lutheran separatists left Germany and eventually established the small community of Zoar in Tuscarawas County, Ohio. The group formed the Society of Separatists of Zoar, in which each person donated his or her property to the community as a whole, and in exchange for their work, the society would provide for them. After decades of economic prosperity, the unity of the village declined, and by 1898 the Zoarites disbanded the society. Peter Kaufmann was a German immigrant and intellectual. He arrived first in Philadelphia, Pennsylvania, in 1820; in 1826 he became professor of languages at the Harmony Society town of Economy, Pennsylvania. In 1827, Kaufmann led the establishment of Teutonia, a utopian community in Columbiana County, Ohio, and published its weekly titled "Teutonia: The Herald of a Better Time." Following this he moved to Canton, Ohio, where he became translator and editor of "Der Vaterlandsfreund und Geist der Zeit" under Solomon Sala. Additionally, Kaufmann wrote a number of books on education, as well as a German almanac. He was also an influential Democrat, counting President Van Buren among his friends, and knew Ralph Waldo Emerson

    Composting of aged reed bed biosolids for beneficial reuse: a case study in New Jersey, USA

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    Reed beds with Phragmites australis (common reed) have been utilized to decrease the water, nutrient and volatile solids content of sewage sludge. An efficient disposal/reuse option was sought for reed bed biosolids accumulated over a 15 year period at a wastewater treatment facility in New Jersey, USA. The study facility had 14 reed beds, each with 1000 wet tons capacity, which were full, and so the solids needed to be removed. Because P. australis is considered an invasive species in New Jersey and several other states in the United States, disposal or reuse of solids containing this plant is regulated. Composting was examined as a potential treatment for destroying the plant’s reproductive rhizomes. The high temperatures achieved during composting were also tested to determine if regulatory criteria for pathogen reduction could be met, making the composted product suitable for unrestricted land application. Preliminary studies indicated the sludge had stabilized to the point where self-heating did not occur. Among the carbon amendments tested in the laboratory to stimulate compositing activity, Phragmites above ground biomass was determined to be most suitable. In a field test, Phragmites above ground biomass was mixed with reed bed biosolids at a 1:2 (w/w) ratio. The temperatures achieved resulted in complete mortality of Phragmites rhizomes. In laboratory tests, rhizomes placed in a drying oven at 50ºC for 24 hours, or 55ºC for 12 hours, showed 100% plant mortality. However, under field conditions pile temperatures could not be maintained long enough for the sludge to meet the USEPA 503 biosolids time-temperature pathogen rule requirements for unrestricted land application, even though sample fecal coliform counts did meet regulatory limits.Peer reviewed

    Anti-factor H autoantibodies block C-terminal recognition function of factor H in hemolytic uremic syndrome

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    The atypical form of the kidney disease hemolytic uremic syndrome (aHUS) is associated with defective complement regulation. In addition to mutations in complement regulators, factor H (FH)specific autoantibodies have been reported for aHUS patients. The aim of the present study was to understand the role of these autoantibodies in aHUS. First, the binding sites of FH autoantibodies from 5 unrelated aHUS patients were mapped using recombinant FH fragments and competitor antibodies. For all 5 autoantibodies, the binding site was localized to the FH C-terminus. In a functional assay, isolated patient IgG inhibited FH binding to C3b. In addition, autoantibody positive patients' plasma caused enhanced hemolysis of sheep erythrocytes, which was reversed by adding FH in excess. These results suggest that aHUS associated FH autoantibodies mimic the effect of C-terminal FH mutations, as they inhibit the regulatory function of FH at cell surfaces by blocking its C-terminal recognition region

    Development of liver size and perfusion after reduced-size liver transplantation in children

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    The technique of segmental liver transplantation (s-LTx) provides a method to overcome the shortage of suitable livers for small recipients. Patient survival rates are parallel to those obtained with whole liver transplantation (w-LTx), For long-term rehabilitation, adaptive liver growth and adequate perfusion is crucial; however, morphometric and hemodynamic parameters in growing children with s-LTx are not available. Seventeen children who received a s-LTx and 25 with a w-LTx who had follow-up evaluation 1 and 2 yr after LTx were studied. Mean age at time of transplantation was 4.3 +/-3.5 yr for s-LTx and 10.3 +/-6.0 yr for w-LTx, mean height 98 +/- 21 cm and 122 +/- 30 cm respectively. At follow-up evaluation mean values for liver enzymes, bilirubin and prothrombin time were in the normal ranges for both groups. Liver dimensions were measured by gray scale ultrasound, and hemodynamic parameters by Doppler sonography in the portal vein and hepatic artery using an Acuson 128 machine. Maximal (V-max), minimal (V-min) and time-average velocity (TAV) were measured and the resistive index (RI) calculated. We found that 1 and 2 yr after LTx liver dimensions were at a mean in the upper normal range of healthy controls. Spleen size was above the normal range and did not show any tendency towards regression. Mean V-max in the hepatic artery in s-LTx and w-LTx was 48 cm/sec vs. 28 cm/sec after 1 yr and 30 cm/sec vs. 35 cm/sec after 2 yr, the RI 0.66 vs. 0.55 and 0.59 vs. 0.73, respectively (p for all parameters >0.05), Maximal portal vein flow was 25 cm/sec in s-LTx vs. 29 cm/sec in w-LTx. Blood flow calculated by vessel diameter and TAV showed no statistical difference between both groups. In conclusion, liver size after s-LTx and w-LTx was increased to the upper normal range, and portal vein blood flow velocities were within the normal range. V-max in the hepatic artery was reduced in s-LTx; however, the reduction was to the same extent as in w-LTx. In the view of long-term functional adaptation, s-LTx is not inferior to w-LTx

    Development of liver size and perfusion after reduced-size liver transplantation in children

    No full text
    The technique of segmental liver transplantation (s-LTx) provides a method to overcome the shortage of suitable livers for small recipients. Patient survival rates are parallel to those obtained with whole liver transplantation (w-LTx), For long-term rehabilitation, adaptive liver growth and adequate perfusion is crucial; however, morphometric and hemodynamic parameters in growing children with s-LTx are not available. Seventeen children who received a s-LTx and 25 with a w-LTx who had follow-up evaluation 1 and 2 yr after LTx were studied. Mean age at time of transplantation was 4.3 +/-3.5 yr for s-LTx and 10.3 +/-6.0 yr for w-LTx, mean height 98 +/- 21 cm and 122 +/- 30 cm respectively. At follow-up evaluation mean values for liver enzymes, bilirubin and prothrombin time were in the normal ranges for both groups. Liver dimensions were measured by gray scale ultrasound, and hemodynamic parameters by Doppler sonography in the portal vein and hepatic artery using an Acuson 128 machine. Maximal (V-max), minimal (V-min) and time-average velocity (TAV) were measured and the resistive index (RI) calculated. We found that 1 and 2 yr after LTx liver dimensions were at a mean in the upper normal range of healthy controls. Spleen size was above the normal range and did not show any tendency towards regression. Mean V-max in the hepatic artery in s-LTx and w-LTx was 48 cm/sec vs. 28 cm/sec after 1 yr and 30 cm/sec vs. 35 cm/sec after 2 yr, the RI 0.66 vs. 0.55 and 0.59 vs. 0.73, respectively (p for all parameters >0.05), Maximal portal vein flow was 25 cm/sec in s-LTx vs. 29 cm/sec in w-LTx. Blood flow calculated by vessel diameter and TAV showed no statistical difference between both groups. In conclusion, liver size after s-LTx and w-LTx was increased to the upper normal range, and portal vein blood flow velocities were within the normal range. V-max in the hepatic artery was reduced in s-LTx; however, the reduction was to the same extent as in w-LTx. In the view of long-term functional adaptation, s-LTx is not inferior to w-LTx

    Zechariah 9-14 as the substructure of 1 Peter’s eschatological program

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    The principal aim of this study is to discern what has shaped the author of 1 Peter to regard Christian suffering as a necessary (1.6) and to-be-expected (4.12) component of faithful allegiance to Jesus Christ. Most research regarding suffering in 1 Peter has limited the scope of inquiry to two particular aspects—its cause and nature, and the strategies that the author of 1 Peter employs in order to enable his addressees to respond in faithfulness. There remains, however, the need for a comprehensive explanation for the source that has generated 1 Peter’s theology of Christian suffering. If Jesus truly is the Christ, God’s chosen redemptive agent who has come to restore God’s people, then how can it be that Christian suffering is a necessary part of discipleship after his coming, death and resurrection? What led the author of 1 Peter to such a startling conclusion, which seems to runs against the grain of the eschatological hopes and expectations of Jewish restoration ideology? This thesis analyzes the appropriation of shepherd and fiery trials imagery, and argues that the author of 1 Peter is dependent upon Zechariah 9-14 for his theology of Christian suffering. Said in another way, the eschatological program of Zechariah 9-14, read through the lens of the Gospel, functions as the substructure for 1 Peter’s eschatology and thus its theology of Christian suffering. In support of this hypothesis, this study highlights the fact that Zechariah 9- 14 was available and appropriated in early Christianity, in particular in the Passion Narrative tradition; that the shepherd imagery of 1 Pet 2.25 is best understood within the milieu of the Passion Narrative tradition, and that it alludes to the eschatological program of Zechariah 9-14; that the fiery trials imagery found in 1 Peter 1.6-7 and 1 Pet 4.12 is distinct from that which we find in Greco-Roman and OT wisdom sources, and that it shares exclusive parallels with some unique features of the eschatological program of Zechariah 9-14; that Zechariah 9-14 offers a more satisfying explanation for the modification of Isa 11.2 in 1 Pet 4.14, the transition from 4.12-19 to 5.1-4, why Peter has oriented his letter with the term διασπορά, and why he has described his addresses as οἶκος τοῦ θεοῦ; and finally that 1 Peter contains an implicit foundational narrative that shares distinct parallels with the eschatological program of Zechariah 9-14. We can conclude that 1 Peter offers a unique vista into the way in which at least one early Christian witness came to understand and to communicate the fact that Christian suffering was a necessary feature of faithful allegiance to Jesus Christ

    A conversation with Thomas Sowell

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    In this episode, host Peter Krogh sits down with Thomas Sowell, the prominent black economist and social commentator. Born in North Carolina, Sowell grew up in Harlem. He received a bachelor's degree from Harvard, a master's degree from Columbia and a PhD from the University of Chicago. In 1980, he became the Rose and Milton Friedman Senior Fellow at Stanford University's Hoover Institution. A prolific author, Sowell frequently provoked controversy with his commentary on race and ethnic conflict. In this interview, Dr. Sowell discusses his latest book, The Economics and Politics of Race: An International Perspective, which examines how different races and ethnicities fare in different societies.Host Peter Krogh sits down with economist and social commentator Thomas Sowell to discuss Sowell's latest book The Economics and Politics of Race
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