3,448 research outputs found
Observation of hc radiative decay hc › ??' and evidence for hc › ??
No full textKolcu, Onur Buğra (Arel Author) --- Makale 69 yazarlıdır.A search for radiative decays of the P-wave spin singlet charmonium resonance hc is performed based on 4.48 × 108 ? events collected with the BESIII detector operating at the BEPCII storage ring. Events of the reaction channels hc › ??' and ?? are observed with a statistical significance of 8.4? and 4.0?, respectively, for the first time. The branching fractions of hc › ??' and hc › ?? are measured to be B(hc › ??' ) = (1.52±0.27±0.29)×10-3 and B(hc › ??) = (4.7±1.5±1.4)×10-4 , respectively, where the first errors are statistical and the second are systematic uncertainties
The Director of Financial Enquiries A Study of the Treasury Career of R. G. Hawtrey, 1919-1939.
No full textThe Director of Financial Enquiries. A Study of the Treasury Career of R. G. Hawtrey, 1919-39.
In 1904 Ralph George Hawtrey, a Cambridge Mathematics graduate, entered the Treasury as Second Class Clerk. Apart from one year of secondment he was to remain employed by the Treasury until 1947. His career progress was modest. He never achieved a position of high administrative responsibility. Only in 1919, at the age of forty, did he achieve the grade of Assistant Secretary. In this position, as Director of Financial Enquiries within the Finance Division of the Treasury, he had no administrative responsibility, but was required to prepare reports on matters of his own choosing or as directed by his Treasury superiors. In his remaining 28 years at the Treasury he made no further career progress. As such, his was an unremarkable career.
His career was only remarkable because, after entering the Treasury, he took up an interest in the subject of Economics – he became a self-taught economist. Having developed his economic understanding through his experiences within the Treasury, it owed little to any previously existing ‘school’. Thus, in 1913, in his first book Good and Bad Trade, he was able to produce the first complete monetary explanation of the trade cycle. His standing as an economist rose even as his civil service career halted. In 1919 he produced a book Currency and Credit which became a standard university text on monetary economics for over a decade. He was appointed visiting Professor of Economics at Harvard for 1928-9, was elected to a fellowship of the British Academy in 1935, appointed Professor of International Economics at the Royal Institute of International Affairs in 1947, knighted (for ‘services to Economics’) in 1956, and elected to an Honorary Fellowship of Trinity College, Cambridge in 1959. As an economist of standing he used his position in the Treasury to criticise the policy-making authorities.
The Financial Enquiries Branch, for which Hawtrey was responsible, has commonly been described as a ‘backwater’ – removed from centre of economic decision-making. Likewise, within studies of the Treasury, there has been a tendency to deprecate Hawtrey as a figure of fun; partly on account of personal inefficiencies and eccentricities, and partly on account of a certain ‘unworldliness’, with his views being tied too closely to his economic theory and divorced from the traditional culture within which the Treasury and the Bank of England had been accustomed to operate.
This thesis will examine the way in which, as an economist, Hawtrey used his position within the Treasury to criticise, and attempt to change, policy. It will concentrate on his differences with the advice of other economists and his differences with the policies of the Treasury and the Bank of England.
The findings of this study are that while much of the criticism of Hawtrey’s career may be true, there were times when Hawtrey was both persuasive and influential. Much of his influence stemmed from his relationship with senior members of the Treasury administration, and whilst there were times when senior staff respected his judgement, there were times when his views ran contrary to the ethos of the Treasury and were ignored. However, even when he was ignored, as he often was, Hawtrey’s criticisms drew attention to the wider implications of policy in such a way that he can be seen as acting as the Treasury’s ‘conscience’. As such, his influence was often not directly on policy but, more subtly, upon the way in which the Treasury’s perception of its responsibilities changed
Photocurrent noise in multi-quantum-well infrared photodetectors
No full textWe report on photocurrent noise in AlGaAs/GaAs quantum-well infrared photodetectors having nominally the same design, except the number of wells N. The power spectral density does not scale as the inverse of the number of wells N in the presence of infrared radiation. These features can be understood by taking into account the nonlinearity arising at high infrared power as a consequence of the nonuniform potential distribution through the quantum-well structure
Effect of alanine substitution with each HC-84 contact residue on HCVpp entry, interaction with CD81, and HC-84 HMAb binding to “epitope-II".
No full text<p>(<b>A</b>) Wt and H77c HCVpp mutants, each bearing a single alanine substitution at a contact residue of HC-84 HMAbs, were produced, normalized by p24 as described in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1002653#s4" target="_blank">Materials and Methods</a>, and employed to infect Huh7.5 cells. Virus entry was assessed by measuring luciferase activity on day 3 p.i. Results are shown as luciferase activity signals in infected cells, relative to signals from cells infected with vectors alone. Data are shown as the mean of three experiments ±SD, with each performed in triplicates. The inset shows incorporation of E1E2 glycoproteins into wt and mutant HCVpp that were partially purified by pelleting virus through a 20% sucrose cushion and followed by Western blot analysis. E2 in the majority of HCVpp mutants and wt were probed with HMAb HC-33.1, and in W420A HCVpp and wt, were re-probed with MAb 6/82a <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1002653#ppat.1002653-Flint1" target="_blank">[29]</a>. E1 was probed with HMAb H-111, an antibody to a linear E1 epitope <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1002653#ppat.1002653-Keck7" target="_blank">[49]</a>. HIV p24 was probed with an anti-HIV p24 antibody as a loading control. The images are composites. (<b>B</b>) Effect of each HC-84 contact residue on E2 binding to CD81. HC-84 epitope- related E2 mutant proteins were expressed in 293 T cells and captured in microtiter plates by GNA. Individual protein expression was normalized by binding of CBH-17, an HCV E2 HMAb to a linear epitope <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1002653#ppat.1002653-Hadlock1" target="_blank">[18]</a>. The wells were then incubated with CD81-LEL at 20 µg/ml. Detection of CD81-LEL captured by wt or mutated E2 was measured with anti-CD81 and shown as percent CD81 binding relative to wt. Data are derived from triplicate wells and shown as the mean of two experiments ± SD. (<b>C</b>) HC-84 HMAb binding to epitope-II by ELISA. Biotinylated-epitope II, aa434–446, was captured by streptavidin in microtiter wells. The wells were then incubated with each HC-84 HMAb at 10 µg/ml, serum (1∶100 dilution) from the individual whose B cells were employed to isolate the HC-84 antibodies, and a normal human serum (1∶100 dilution), as a negative control. Specific binding was detected by anti-human IgG-labeled horseradish peroxidase. (<b>D</b>) Peptide (epitope-II) inhibition of HC-84 antibody binding to E2. Recombinant H77C E1E2 lysate was captured by GNA in microtiter wells. The wells were then incubated with selected HC-84 HMAbs and two controls, HC-11 and R04 that were pre-incubated with epitope-II (labeled as peptide) at indicated concentrations. Binding was detected after anti-human IgG-labeled horseradish peroxidase. For C and D, the <i>y</i>-axis shows the mean optical density values for triplicate wells, the mean of two experiments ±SD.</p
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Hydrologic Data and Evaluation for Model Validation Wells, MV-1, MV-2, and MV-3 near the Project Shoal Area
No full textIn 2006, a drilling campaign was conducted at the Project Shoal Area (PSA) to provide information for model validation, emplace long-term monitoring wells, and develop baseline geochemistry for long term hydrologic monitoring. Water levels were monitored in the vicinity of the drilling, in the existing wells HC-1 and HC-6, as well as in the newly drilled wells, MV-1, MV-2 and MV-3 and their associated piezometers. Periodic water level measurements were also made in existing wells HC-2, HC-3, HC-4, HC-5 and HC-7. A lithium bromide chemical tracer was added to drilling fluids during the installation of the monitoring and validation (MV) wells and piezometers. The zones of interest were the fractured, jointed and faulted horizons within a granitic body. These horizons generally have moderate hydraulic conductivities. As a result, the wells and their shallower piezometers required strenuous purging and development to remove introduced drilling fluids as evidenced by bromide concentrations. After airlift and surging well development procedures, the wells were pumped continuously until the bromide concentration was less then 1 milligram per liter (mg/L). Water quality samples were collected after the well development was completed. Tritium scans were preformed before other analyses to ensure the absence of high levels of radioactivity. Tritium levels were less than 2,000 pico-curies per liter. Samples were also analyzed for carbon-14 and iodine-129, stable isotopes of oxygen and hydrogen, as well as major cations and anions. Aquifer tests were performed in each MV well after the bromide concentration fell below acceptable levels. Water level data from the aquifer tests were used to compute aquifer hydraulic conductivity and transmissivit
Late Gothic architecture in South West England : four major centres of building activity at Wells, Bristol, Sherbourne and Bath
No full textBy 1360 the Perpendicular style was established as the successor to Decorated
architecture. During the subsequent one hundred and eighty years, until the Reformation,
major building work was carried out at four great churches in the south west of England.
The complete reconstructions of St Mary Redcliffe, Sherborne Abbey and Bath Abbey, and
considerable work to the precinct at Wells Cathedral during this period, form the basis for
this thesis. Through a study of each of these major centres, the issues of workshop identity
and stylistic trendsetters are considered.
It is shown how the interpretation of documentary evidence has impeded an
understanding of these buildings, which can be revealed by an analysis of the fabric. Based
primarily on a methodology of buildings archaeology and assessment of moulding profiles,
traditional assumptions concerning the chronology and patronage are challenged.
The new chronology for works at Sherborne Abbey, and the redating of the
commencement of Bath Abbey further our understanding of the nature of masons'
workshops, patronage and stylistic development within a regional context. Introspection in
masons' workshops during the 15th century, and retrospection in later design in the region,
demonstrates a reliance on the innovations of the 14th century, and the significance of the
parish church tradition in the region, respectively. The thesis concludes with a discussion on
the influence of major church workshops on domestic architecture, and the impact of the
dissemination of the lodges in the early 16th century
Impacts on groundwater quality from abandoned hydrocarbon wells - final report
No full textThis report details a reconnaissance investigation carried out between 2016 and 2018 from a British
Geological Survey (BGS)–Environment Agency (EA) collaboration on the impacts of abandoned
hydrocarbon (HC) wells on groundwater quality in England. The investigation involved collation of a
database of HC wells that were identified from records provided by DECC (Department of Energy &
Climate Change; now BEIS: Business, Energy & Industrial Strategy) as being abandoned (as opposed
to operational or unspecified), categorising according to factors such as oil or gas designation, depth of
HC resource, time since abandonment, productive life, absence of active wells nearby, and occurrence
and type of overlying aquifer(s). From this categorisation, a subset of 27 sites were shortlisted for further
investigation and fact sheets were produced for each outlining regional geology, hydrogeology and
potential groundwater monitoring points in the area. Using these factsheets, four study areas were
assessed as being most suitable for further field investigation. These comprised two gas fields: Nooks
Farm (Staffordshire), and Ashdown (Sussex), and two oil fields: Hemswell (Lincolnshire) and Lomer
(Hampshire).
Groundwater sampling campaigns were conducted in 2016–2017 in the four study areas, with potential
sampling points identified within a 5 km buffer zone around (downstream of) the HC well or HC field.
In several areas, the number of sampling points was very limited as locations of HC wells do not
necessarily have any relationship with locations of overlying aquifers. In others, large numbers of sites
were deemed unsuitable for sampling, for reasons including disuse, decommissioning, safety or lack of
access. This made representative sampling of groundwater a severe challenge. Suitable sites from the
four study areas were sampled twice during the project, with a total of 48 groundwater samples being
collected over the two campaigns.
Results from both sampling rounds have shown that the presence of hydrocarbons in the groundwater
is limited. In the first sampling round, a maximum dissolved methane (CH4) concentration of 407 μg/L
was recorded. However, this relatively high value was not repeated when the site was visited during the
second round of groundwater sampling. The value was below the threshold required for δ13CCH4 isotopic
analysis. Some groundwater samples showed detectable quantities of organic compounds including
VOCs (volatile organic compounds) and PAHs (polycyclic aromatic hydrocarbons) as well as
pesticides, herbicides, fungicides, surfactants, analgesics and veterinary compounds. These were,
however, almost invariably present in low concentrations, none could be linked unequivocally to the
presence of abandoned HC wells and many were clearly due to other anthropogenic activities.
As a result of the difficulties finding representative and suitable groundwater sampling sites, a further
reconnaissance was undertaken in May 2017 to identify potential alternative gas and oil fields. This
confirmed further the difficulties in finding suitable areas for investigating groundwater quality and
further groundwater sampling was therefore not attempted. An alternative approach was used to
investigate two abandoned HC well areas: Ashdown, one of the original study areas, and a new location
at Bolney (also Sussex). A soil gas survey was completed at each of these locations in order to
investigate whether soil gas proximal to the former well location contained any evidence of HC leakage.
Due to poor ground conditions at the time of sampling, the results are ambiguous, but do show elevated
concentrations of both CO2 and CH4. Further work in dry ground conditions would be required to say
with certainty that these concentrations are linked directly to the presence of the gas wells
Financial analysis and evaluation of company HC Betons Ltd
No full textDiplomdarba nosaukums: Uzņēmuma SIA HC Betons finanšu analīze un novērtējums
Diplomdarba mērķis ir uz finanšu analīzes pamata izvērtēt uzņēmuma SIA HC Betons esošo finansiālo situāciju un izstrādāt priekšlikumus finansiālā stāvokļa uzlabošanai.
Teorētiskajā daļā apskatīti finanšu analīzes teorētiskie aspekti. Praktiskajā daļā autore veica uzņēmuma SIA HC Betons finanšu analīzi par 2009., 2010., un 2011.gadu. Analītiskajā daļā autore salīdzina rādītājus ar konkurējošo uzņēmumu SIA Cemex.
Autore secinājusi, ka uzņēmumam ir finansiālas grūtības, bet pēc autores domām, uzņēmums tuvāko gadu laikā nebankrotēs.
Diplomdarba apjoms ir 78 lapaspuses, tas sastāv no 3 daļām, 12 tabulām, 5 attēliem un 12 pielikumiem.
Atslēgvārdi: analīze, likviditāte, bankrots, koeficienti.Diploma thesis: Financial Analysis and Evaluation of Company HC Betons Ltd.
The aim of the diploma paper is to evaluate company’s HC Betons Ltd current financial situation based on financial analysis and make suggestions for improvement of the financial position.
Theoretical aspects of financial analysis are discussed in the theoretical part of the paper. In the practical part author has performed company’s HC Betons Ltd financial analysis of the years 2009, 2010 and 2011. In the analytical part author compares ratios of a competing company Cemex Ltd.
The author concludes that the company is in financial difficulties, but according to the author’s thoughts, the company will not bankrupt in the coming years.
The volume of the diploma paper is 78 pages; it consists of 3 parts, 12 tables, 5 images and 12 appendices.
Keywords: analysis, liquidity, bankruptcy, ratios
Metabolic profiling and population screening of analgesic usage in nuclear magnetic resonance spectroscopy-based large-scale epidemiologic studies
No full textThe application of a 1H nuclear magnetic resonance (NMR) spectroscopy-based screening method for determining the use of two widely available analgesics (acetaminophen and ibuprofen) in epidemiologic studies has been investigated. We used samples and data from the cross-sectional INTERMAP Study involving participants from Japan (n = 1145), China (n = 839), U.K. (n = 501), and the U.S. (n = 2195). An orthogonal projection to latent structures discriminant analysis (OPLS-DA) algorithm with an incorporated Monte Carlo resampling function was applied to the NMR data set to determine which spectra contained analgesic metabolites. OPLS-DA preprocessing parameters (normalization, bin width, scaling, and input parameters) were assessed systematically to identify an optimal acetaminophen prediction model. Subsets of INTERMAP spectra were examined to verify and validate the presence/absence of acetaminophen/ibuprofen based on known chemical shift and coupling patterns. The optimized and validated acetaminophen model correctly predicted 98.2%, and the ibuprofen model correctly predicted 99.0% of the urine specimens containing these drug metabolites. The acetaminophen and ibuprofen models were subsequently used to predict the presence/absence of these drug metabolites for the remaining INTERMAP specimens. The acetaminophen model identified 415 out of 8436 spectra as containing acetaminophen metabolite signals while the ibuprofen model identified 245 out of 8604 spectra as containing ibuprofen metabolite signals from the global data set after excluding samples used to construct the prediction models. The NMR-based metabolic screening strategy provides a new objective approach for evaluation of self-reported medication data and is extendable to other aspects of population xenometabolome profiling
Magnetic proximity-enhanced Curie temperature of Cr-doped Bi2Se3 thin films
No full textBeam time awarded on ID32 at the ESRF (Proposal No. HC-1282) and on I10 at the Diamond Light Source (Proposal No. SI-10207) are acknowledged. T.H. acknowledges the John Fell Oxford University Press (OUP) Research Fund. A.A.B. was supported by Diamond Light Source and together with L.J.C.M. by EPSRC through Doctoral Training Awards.We report a study on the transition temperature TC of Cr-doped topological insulator thin films, where an increase in the ferromagnetic onset can provide a pathway towards low-power spintronics in the future. Arrott plots, measured by surface-sensitive x-ray magnetic circular dichroism at the Cr L2,3 edge as a function of field at various low temperatures, give a TC ≈ 7K for the pristine surface. This is comparable to the bulk value of the film, which means that there is no indication that the spontaneous magnetization is different near the surface. Evaporation of a thin layer of Co onto the pristine surface of the in-situ cleaved sample increases the ordering temperature near the surface to ∼19K, while in the bulk it rises to ∼10K. X-ray absorption spectroscopy shows that Cr enters the Bi2Se3 host matrix in a divalent state, and is unchanged by the Co deposition. These results demonstrate a straightforward procedure to increase the transition temperature of doped topological insulators.Peer reviewe
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